An Observational Study of Patients With Dermatologic Disease
for Vitiligo
Sites in Philadelphia +2 more locations
Sponsor: Target PharmaSolutions, Inc.
Sex: All·Age: All ages
Code: NCT07748169·Recruiting·Listed Aug 5, 2026
Clinical Trials at University of Pennsylvania
As of August 2026, 305 paid clinical trials are recruiting at University of Pennsylvania, located at Perelman School of Medicine at the University of Pennsylvania, 3400 Civic Center Blvd, Philadelphia, PA 19104, phone (215) 898-8001 in Philadelphia, Pennsylvania. Active studies at this site cover conditions such as Breast Cancer, Heart Failure and Ovarian Cancer. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Philadelphia
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
Intervention to Improve Parent Communication About Sexuality
for HIV/STI Incidence
1 location in Philadelphia
Sponsor: University of Pennsylvania
Sex: All·Age: 12 - 100·Accepts healthy volunteers
Code: NCT07672067·Recruiting·Listed Jun 26, 2026
Reward Sensitivity Digital Intervention for Suicide Risk
for Suicidal Ideation
1 location in Philadelphia
Sponsor: University of Pennsylvania
Sex: All·Age: 13 - 17
Code: NCT07661901·Recruiting·Listed Jun 22, 2026
308 clinical trials at University of Pennsylvania
·Clear filters·Parasternal Extravascular ICD System Pivotal Clinical Investigation (ALARION EV) Study
for Ventricular Arrythmia
Sites in Philadelphia, Hershey +25 more locations
Sponsor: AtaCor Medical, Inc.
Sex: All·Age: 18+
Code: NCT07324031·Recruiting·Listed Jan 2026
A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer
for CRC (Colorectal Cancer)
Drug: Bevacizumab
Sites in Philadelphia, Doylestown +69 more locations
Sponsor: Incyte Corporation
Sex: All·Age: 18+
Code: NCT07284849·Phase 3·Recruiting·Listed Dec 2025
A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma
for Multiple Myeloma
Sites in Philadelphia +29 more locations
Sponsor: Janssen Research & Development, LLC
Sex: All·Age: 18+
Code: NCT07266441·Phase 2·Recruiting·Listed Dec 2025
A Study to Find Out if BI 764198 Helps Adults and Adolescents With a Kidney Condition Called Focal Segmental Glomerulosclerosis (FSGS)
for Focal Segmental Glomerulosclerosis
Sites in Philadelphia, Exton +69 more locations
Sponsor: Boehringer Ingelheim
Sex: All·Age: 12+
Code: NCT07220083·Phase 3·Recruiting·Listed Oct 2025
OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events
for Cardiovascular Disease
Drug: Olpasiran
Sites in Philadelphia, Pottstown +197 more locations
Sponsor: Amgen
Sex: All·Age: 50 - 105
Code: NCT07136012·Phase 3·Recruiting·Listed Aug 2025
A Study of Icotrokinra in Participants With Moderately to Severely Active Crohn's Disease
for Crohn Disease
Sites in Philadelphia, Hershey +52 more locations
Sponsor: Janssen Research & Development, LLC
Sex: All·Age: 18+
Code: NCT07196722·Phase 2, Phase 3·Recruiting·Listed Sep 2025
A Protocol of Icotrokinra Therapy in Adult and Adolescent Participants With Moderately to Severely Active Ulcerative Colitis
for Colitis, Ulcerative
Sites in Philadelphia, Hershey +48 more locations
Sponsor: Janssen Research & Development, LLC
Sex: All·Age: 12+
Code: NCT07196748·Phase 3·Recruiting·Listed Sep 2025
Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)
for Solid Tumors
Sites in Philadelphia, Pittsburgh +40 more locations
Sponsor: Merck Sharp & Dohme LLC
Sex: All·Age: 18+
Code: NCT03486873·Phase 3·Recruiting·Listed Apr 2018
Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML
for Acute Myeloid Leukemia (AML)
Sites in Philadelphia +41 more locations
Sponsor: Kura Oncology, Inc.
Sex: All·Age: 18+
Code: NCT07007312·Phase 3·Recruiting·Listed Jun 2025
A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.
for Epithelial Ovarian Cancer
Sites in Philadelphia, Bethlehem +64 more locations
Sponsor: AbbVie
Sex: Female·Age: 18+
Code: NCT06890338·Phase 2·Recruiting·Listed Mar 2025
A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures
for Primary Generalized Tonic-Clonic Seizures
Drug: XEN1101
Sites in Philadelphia, Pittsburgh +46 more locations
Sponsor: Xenon Pharmaceuticals Inc.
Sex: All·Age: 12+
Code: NCT05667142·Phase 3·Recruiting·Listed Dec 2022
Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms
for Depressive Disorder, Major
Drug: Seltorexant
Sites in Philadelphia +41 more locations
Sponsor: Janssen Research & Development, LLC
Sex: All·Age: 18 - 74
Code: NCT06559306·Phase 3·Recruiting·Listed Aug 2024
Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled Study
for Moderate Aortic Valve Stenosis
Drug: Ataciguat
Sites in Philadelphia, Lancaster +67 more locations
Sponsor: Kardigan, Inc.
Sex: All·Age: 50+
Code: NCT07001800·Phase 2, Phase 3·Recruiting·Listed Jun 2025
Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine Tumors
for Pancreatic Neuroendocrine Tumor (pNET)
Sites in Philadelphia, Pittsburgh +38 more locations
Sponsor: Exelixis
Sex: All·Age: 18+
Code: NCT06943755·Phase 2, Phase 3·Recruiting·Listed Apr 2025
A Study to Evaluate Avacopan in Participants With ANCA-associated Vasculitis
for Antineutrophil Cytoplasmic Antibody-associated Vasculitis
Drug: Avacopan
Sites in Philadelphia, Pittsburgh +56 more locations
Sponsor: Amgen
Sex: All·Age: 18 - 100
Code: NCT06072482·Phase 4·Recruiting·Listed Oct 2023
ANCHOR Study: A Study to Assess the Safety and Efficacy of ABBV-CLS-628 in Adult Participants With Autosomal Dominant Polycystic Kidney Disease (ADPKD)
for Autosomal Dominant Polycystic Kidney Disease
Sites in Philadelphia, Bethlehem +35 more locations
Sponsor: Calico Life Sciences LLC
Sex: All·Age: 18 - 55
Code: NCT06902558·Phase 2·Recruiting·Listed Mar 2025
A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease
for Moderately to Severely Active Crohns Disease
Drug: Afimkibart
Sites in Philadelphia +58 more locations
Sponsor: Hoffmann-La Roche
Sex: All·Age: 16 - 80
Code: NCT06819891·Phase 3·Recruiting·Listed Feb 2025
Shield Post-Approval Study Protocol
for Colo-rectal Cancer
Sites in Philadelphia, Pottstown +56 more locations
Sponsor: Guardant Health, Inc.
Sex: All·Age: 45 - 81·Accepts healthy volunteers
Code: NCT06880055·Recruiting·Listed Mar 2025
A Long-term Study for Participants Previously Treated With Ciltacabtagene Autoleucel
for Multiple Myeloma
Sites in Philadelphia, Pittsburgh +26 more locations
Sponsor: Janssen Research & Development, LLC
Sex: All·Age: 18+
Code: NCT05201781·Phase 4·Recruiting·Listed Jan 2022
FORAGER-1: A Study of LOXO-435 (LY3866288) in Participants With Cancer With a Change in a Gene Called FGFR3
for Urinary Bladder Neoplasms
Sites in Philadelphia, Lancaster +39 more locations
Sponsor: Eli Lilly and Company
Sex: All·Age: 18+
Code: NCT05614739·Phase 1·Recruiting·Listed Nov 2022
Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease
for Crohn's Disease
Sites in Philadelphia +55 more locations
Sponsor: AbbVie
Sex: All·Age: 18 - 75
Code: NCT06548542·Phase 2·Recruiting·Listed Aug 2024
RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses
for Adjustment Disorder
Sites in Philadelphia +29 more locations
Sponsor: Reunion Neuroscience Inc
Sex: All·Age: 18 - 80
Code: NCT07002034·Phase 2·Recruiting·Listed Jun 2025
A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression
for Treatment Resistant Depression
Sites in Philadelphia, Moosic +51 more locations
Sponsor: LivaNova
Sex: All·Age: 18+
Code: NCT03887715·Recruiting·Listed Mar 2019
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
for Heart Failure
Sites in Philadelphia, Hershey +55 more locations
Sponsor: Abbott Medical Devices
Sex: All·Age: 18+
Code: NCT06526195·Recruiting·Listed Jul 2024
A Longitudinal Multi-Omic Biomarker Profiling Study of Patients With Head & Neck Squamous Cell Carcinoma (HNSCC)
for Head and Neck Squamous Cell Carcinoma
Sites in Philadelphia, York +27 more locations
Sponsor: Tempus AI
Sex: All·Age: 18+
Code: NCT06163534·Recruiting·Listed Dec 2023
DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
for Pulmonary Hypertension Due to Lung Diseases and Hypoxia
Sites in Philadelphia, Bethlehem +64 more locations
Sponsor: United Therapeutics
Sex: All·Age: 18+
Code: NCT06388421·Recruiting·Listed Apr 2024
A Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy
for Focal Epilepsy
Drug: BHV-7000
Sites in Philadelphia, Pittsburgh +46 more locations
Sponsor: Biohaven Therapeutics Ltd.
Sex: All·Age: 18 - 75
Code: NCT06132893·Phase 2, Phase 3·Recruiting·Listed Nov 2023
The GORE VBX FORWARD Clinical Study: A Comparison of the GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis to Bare Metal Stenting for Patients With Complex Iliac Occlusive Disease
for Aortoiliac Occlusive Disease
Sites in Philadelphia +22 more locations
Sponsor: W.L.Gore & Associates
Sex: All·Age: 18+
Code: NCT05811364·Recruiting·Listed Apr 2023
A Study of Tacrolimus/Methotrexate/Ruxolitinib Versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in Non-Myeloablative/Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell Transplantation (BMT CTN 2203)
for Graft-versus-host Disease (GVHD)
Drug: Ruxolitinib
Sites in Philadelphia +29 more locations
Sponsor: Incyte Corporation
Sex: All·Age: 18+
Code: NCT06615050·Phase 3·Recruiting·Listed Sep 2024
Phase 2 Study to Evaluate Safety and Efficacy of Cretostimogene Grenadenorepvec in High-Risk NMIBC
for High-Risk Non-Muscle-Invasive Bladder Cancer
Sites in Philadelphia, Bala-Cynwyd +59 more locations
Sponsor: CG Oncology, Inc.
Sex: All·Age: 18+
Code: NCT06567743·Phase 2·Recruiting·Listed Aug 2024
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
for Functional Mitral Regurgitation
Sites in Philadelphia, Wynnewood +49 more locations
Sponsor: Cardiac Dimensions, Inc.
Sex: All·Age: 18+
Code: NCT03142152·Recruiting·Listed May 2017
PROMISE III: Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening Ischemia
for Critical Limb Ischemia
Sites in Philadelphia +7 more locations
Sponsor: LimFlow, Inc.
Sex: All·Age: 18 - 95
Code: NCT05313165·Recruiting·Listed Apr 2022
A Study of the Efficacy and Safety of DMX-200 in Patients With FSGS Who Are Receiving an ARB
for FSGS
Sites in Philadelphia +19 more locations
Sponsor: Dimerix Bioscience Pty Ltd
Sex: All·Age: 12 - 80
Code: NCT05183646·Phase 3·Recruiting·Listed Jan 2022
Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve System (FASTR-II) (IDE-G210258)
for Acute Decompensated Heart Failure
Sites in Philadelphia +36 more locations
Sponsor: Reprieve Cardiovascular, Inc
Sex: All·Age: 22+
Code: NCT06898515·Phase 3·Recruiting·Listed Mar 2025
CATALINA-2: A Clinical Study of TORL-1-23 in Platinum-resistant Ovarian Cancer.
for Epithelial Ovarian Cancer
Sites in Philadelphia, Doylestown +24 more locations
Sponsor: TORL Biotherapeutics, LLC
Sex: Female·Age: 18+
Code: NCT06690775·Phase 2·Recruiting·Listed Nov 2024
ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
for Bladder Carcinoma
Sites in Philadelphia, York +25 more locations
Sponsor: Guardant Health, Inc.
Sex: All·Age: 18+
Code: NCT05059444·Recruiting·Listed Sep 2021
A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)
for Treatment Resistant Depression
Sites in Philadelphia, Moosic +32 more locations
Sponsor: atai Therapeutics, Inc.
Sex: All·Age: 18 - 65
Code: NCT06524830·Phase 2·Recruiting·Listed Jul 2024
Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Esophagus
for Esophageal Stricture
Sites in Philadelphia, Pittsburgh +32 more locations
Sponsor: GIE Medical
Sex: All·Age: 22+
Code: NCT05561114·Phase 3·Recruiting·Listed Sep 2022
Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Bowel
for Bowel
Sites in Philadelphia, Pittsburgh +31 more locations
Sponsor: GIE Medical
Sex: All·Age: 22+
Code: NCT05561127·Phase 3·Recruiting·Listed Sep 2022
CAR-T Long Term Follow Up (LTFU) Study
for Long Term Safety of Patients Receiving CAR-T in an Eligible Clinical Trial or Managed Access Program
Sites in Philadelphia +40 more locations
Sponsor: Novartis Pharmaceuticals
Sex: All·Age: 0 - 100
Code: NCT02445222·Phase 3·Recruiting·Listed May 2015
Common conditions studied in Philadelphia
- Breast Cancer (35 active studies)
- Cancer (24 active studies)
- Heart Failure (21 active studies)
- Ovarian Cancer (21 active studies)
- Prostate Cancer (21 active studies)
- Advanced Solid Tumor (18 active studies)
Leading research sponsors in Philadelphia
- University of Pennsylvania
- Abramson Cancer Center at Penn Medicine
- Children's Hospital of Philadelphia
- Thomas Jefferson University
- National Cancer Institute (NCI)
Frequently asked questions
How many paid clinical trials are currently recruiting in Philadelphia?
There are approximately 1,975 recruiting clinical trials in Philadelphia, Pennsylvania listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Philadelphia pay participants?
Most recruiting trials in Philadelphia compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Philadelphia?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Philadelphia?
The most common conditions under active study in Philadelphia include Breast Cancer (35), Cancer (24), Heart Failure (21), Ovarian Cancer (21), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Philadelphia?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Philadelphia on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Philadelphia?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Philadelphia?
Recruiting research sites in Philadelphia include University of Pennsylvania, Children's Hospital of Philadelphia, Thomas Jefferson University Hospital, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Philadelphia right now?
The largest active categories in Philadelphia are Cancer & tumors (555), Neurology & pain (111), Cardiovascular (107). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
What is the address of University of Pennsylvania?
University of Pennsylvania is located at Perelman School of Medicine at the University of Pennsylvania, 3400 Civic Center Blvd, Philadelphia, PA 19104. Use the Google Maps link in the intro above to get directions.
How do I contact University of Pennsylvania?
You can reach University of Pennsylvania by phone at (215) 898-8001. For questions about a specific trial, use the study coordinator contact listed on the individual study record — click any trial title above to open it.
Browse more clinical trials
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