Paid Clinical Trials in Rapid City, SD

As of July 2026, 61 paid clinical trials are recruiting in Rapid City, South Dakota. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 31, 2026.

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56 clinical trials

Lakota Family Acceptance Project

for LGBTQ

Sites in Rapid City & Pine Ridge

Sponsor: University of Michigan

Sex: All·Age: 13+·Accepts healthy volunteers

Code: NCT07326748·Recruiting·Listed Jan 2026

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Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)

for Recurrent Lung Non-Small Cell Carcinoma

Drug: Cemiplimab

Sites in Rapid City, Sioux Falls +379 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06616584·Phase 2, Phase 3·Recruiting·Listed Sep 2024

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Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

for Breast Carcinoma

Sites in Rapid City +463 more locations

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT06418204·Recruiting·Listed May 2024

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A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

for Advanced Pancreatic Carcinoma

Sites in Rapid City, Sioux Falls +107 more locations

Sponsor: Sameek Roychowdhury

Sex: All·Age: 18+

Code: NCT06906562·Phase 2·Recruiting·Listed Apr 2025

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Together Overcoming Diabetes - Great Plains

for Diabetes

1 location in Rapid City

Sponsor: Johns Hopkins Bloomberg School of Public Health

Sex: All·Age: 10+

Code: NCT06770673·Recruiting·Listed Jan 2025

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Healing Within: Mindfulness Smoking Cessation Intervention

for Smoking Cessation

1 location in Rapid City

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT07013968·Recruiting·Listed Jun 2025

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Atezolizumab in Combination With a Multi-Kinase Inhibitor for the Treatment of Unresectable, Locally Advanced, or Metastatic Liver Cancer

for Locally Advanced Hepatocellular Carcinoma

Drug: Atezolizumab

Sites in Rapid City +11 more locations

Sponsor: Academic and Community Cancer Research United

Sex: All·Age: 18+

Code: NCT05168163·Phase 2·Recruiting·Listed Dec 2021

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Smoking Cessation Intervention for American Indian Women Experiencing Intimate Partner Violence

for Smoking Cessation

1 location in Rapid City

Sponsor: Black Hills Center for American Indian Health

Sex: Female·Age: 18+

Code: NCT06357767·Recruiting·Listed Apr 2024

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A Study of Efficacy and Safety of Depemokimab Compared With Placebo in Adults and Adolescents With at Risk Type 2 Asthma

for Asthma

Drug: Depemokimab

Sites in Rapid City +7 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 12+

Code: NCT07456033·Phase 3·Recruiting·Listed Mar 2026

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A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease

for Chronic Obstructive Pulmonary Disease (COPD)

Sites in Rapid City +75 more locations

Sponsor: AstraZeneca

Sex: All·Age: 40+

Code: NCT07082738·Phase 2·Recruiting·Listed Jul 2025

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A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event

for Cardiovascular Disease

Sites in Rapid City +295 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07000357·Phase 3·Recruiting·Listed Jun 2025

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A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00007)

for Chronic Obstructive Pulmonary Disease (COPD)

Sites in Rapid City +61 more locations

Sponsor: AstraZeneca

Sex: All·Age: 40 - 80

Code: NCT06878261·Phase 3·Recruiting·Listed Mar 2025

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Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

for Heart Failure and Impaired Kidney Function

Drug: Dapagliflozin

Sites in Rapid City +112 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT06307652·Phase 3·Recruiting·Listed Mar 2024

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A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease

for COPD (Chronic Obstructive Pulmonary Disease)

Sites in Rapid City, Sioux Falls +133 more locations

Sponsor: AstraZeneca

Sex: All·Age: 40 - 80

Code: NCT06283966·Phase 3·Recruiting·Listed Feb 2024

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Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACS

for Acute Coronary Syndrome

Sites in Rapid City +147 more locations

Sponsor: DalCor Pharmaceuticals

Sex: All·Age: 45+

Code: NCT05918861·Phase 3·Recruiting·Listed Jun 2023

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