Paid Clinical Trials in South Dakota

South Dakota has 310 paid clinical trials enrolling now across cities including Sioux Falls, Rapid City and Pierre. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in South Dakota include National Cancer Institute (NCI), AstraZeneca and Children's Oncology Group, running studies across oncology, cardiology, neurology, and more. The most actively recruiting conditions are Heart Failure, Breast Cancer, Ovarian Cancer, Endometrial Cancer — browse the full list or use the filters to match your diagnosis. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .

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Newly added in South Dakota

Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.

294 clinical trials

A Phase 2, Randomized, Placebo Controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL 3007 in Combination With Syfovre/Pegcetacoplan (APL-2) in Patients Diagnosed With Geographic Atrophy Secondary to Age Related Macular Degeneratio

for Geographic Atrophy Secondary to Age-related Macular Degeneration
Sites in Sioux Falls +77 more locations
Sponsor: Apellis Pharmaceuticals, Inc.
Sex: All·Age: 60+
Code: NCT07215390·Phase 2·Recruiting·Listed Oct 2025

Common conditions studied in South Dakota

  • Heart Failure (12 active studies)
  • Breast Cancer (11 active studies)
  • Ovarian Cancer (9 active studies)
  • Endometrial Cancer (8 active studies)
  • Stage IV Lung Cancer AJCC v8 (7 active studies)
  • Malignant Solid Neoplasm (5 active studies)

Leading research sponsors in South Dakota

  • National Cancer Institute (NCI)
  • AstraZeneca
  • Children's Oncology Group
  • Alliance for Clinical Trials in Oncology
  • Merck Sharp & Dohme LLC

Frequently asked questions

How many paid clinical trials are currently recruiting in South Dakota?

There are approximately 310 recruiting clinical trials in South Dakota listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.

Do clinical trials in South Dakota pay participants?

Most recruiting trials in South Dakota compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.

Who can participate in a clinical trial in South Dakota?

Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.

What conditions are most commonly studied in South Dakota?

The most common conditions under active study in South Dakota include Heart Failure (12), Breast Cancer (11), Ovarian Cancer (9), Endometrial Cancer (8), among many others. Browse the list above to explore every recruiting trial.

Are there clinical trials for healthy volunteers in South Dakota?

Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in South Dakota on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.

How do I enroll in a clinical trial in South Dakota?

Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.

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Related healthcare resources in South Dakota

Trials by condition in South Dakota