Oncology Clinical Trials in San Diego, CA

As of July 2026, 107 paid clinical trials are recruiting for Oncology in San Diego, California. Oncology trials evaluate immunotherapies, targeted therapies, antibody-drug conjugates, and combination regimens across solid tumors and blood cancers — from early-phase first-in-human studies to phase 3 registration trials. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 17, 2026.

Filter results

Filter results

State

City

Facility

Recruitment status

Phase

Study type

Intervention

Condition

Sex

Age

Healthy volunteers only

108 clinical trials for Oncology

·Clear filters·↓ Download CSV

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

for Lung Non-Small Cell Carcinoma

Sites in San Diego, La Jolla +638 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04267848·Phase 3·Recruiting·Listed Feb 2020

Apply to this trial

Mobile Health for Adherence in Breast Cancer Patients

for Anatomic Stage IV Breast Cancer AJCC v8

Sites in San Diego, San Marcos +457 more locations

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06112613·Recruiting·Listed Nov 2023

Apply to this trial

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

for Advanced Malignant Solid Neoplasm

Sites in San Diego, La Jolla +428 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: All ages

Code: NCT05564377·Phase 2·Recruiting·Listed Oct 2022

Apply to this trial

E-Mindfulness Approaches for Living After Breast Cancer

for Breast Cancer

Sites in San Diego, San Marcos +355 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18 - 50

Code: NCT06748222·Phase 3·Recruiting·Listed Dec 2024

Apply to this trial

Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

for Biochemically Recurrent Prostate Carcinoma

Drug: Apalutamide

Sites in San Diego, La Jolla +276 more locations

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: Male·Age: 18+

Code: NCT04423211·Phase 3·Recruiting·Listed Jun 2020

Apply to this trial

Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial

for Metastatic Renal Cell Carcinoma

Sites in San Diego, La Jolla +278 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05327686·Phase 2·Recruiting·Listed Apr 2022

Apply to this trial

Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer

for Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8

Sites in San Diego, La Jolla +144 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT06532279·Phase 2·Recruiting·Listed Aug 2024

Apply to this trial

Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)

for Malignant Female Reproductive System Neoplasm

Sites in San Diego, La Jolla +175 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06126276·Phase 2·Recruiting·Listed Nov 2023

Apply to this trial

Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain

for Anatomic Stage IV Breast Cancer AJCC v8

Sites in San Diego, La Jolla +255 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT06500455·Phase 3·Recruiting·Listed Jul 2024

Apply to this trial

Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

for B Acute Lymphoblastic Leukemia

Sites in San Diego, Orange +186 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 365 Days - 25

Code: NCT03959085·Phase 3·Recruiting·Listed May 2019

Apply to this trial

A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

for Hematologic Malignancies

Sites in San Diego, La Jolla +111 more locations

Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All·Age: All ages

Code: NCT01351545·Recruiting·Listed May 2011

Apply to this trial

A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

for Acute Myeloid Leukemia

Sites in San Diego, Orange +169 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT04293562·Phase 3·Recruiting·Listed Mar 2020

Apply to this trial

The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

for Acute Lymphoblastic Leukemia

Sites in San Diego, Orange +154 more locations

Sponsor: PedAL BCU, LLC

Sex: All·Age: Up to 22

Code: NCT04726241·Phase 1, Phase 2·Recruiting·Listed Jan 2021

Apply to this trial

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

for Ganglioneuroblastoma, Nodular

Sites in San Diego, Orange +151 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 30

Code: NCT06172296·Phase 3·Recruiting·Listed Dec 2023

Apply to this trial

A Study of Tarlatamab for People With Prostate Cancer

for Metastatic Prostate Cancer

Drug: Tarlatamab

Sites in San Diego, San Francisco +8 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Male·Age: 18+

Code: NCT07111507·Phase 2·Recruiting·Listed Aug 2025

Apply to this trial

Colonoscopy vs Stool Testing for Older Adults With Colon Polyps

for Colorectal Polyp

Sites in San Diego, Walnut Creek +14 more locations

Sponsor: Dartmouth-Hitchcock Medical Center

Sex: All·Age: 65 - 82

Code: NCT05612347·Recruiting·Listed Nov 2022

Apply to this trial

Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors

for Neuroblastoma

Sites in San Diego, Oakland +19 more locations

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: Up to 30

Code: NCT06541262·Phase 1, Phase 2·Recruiting·Listed Aug 2024

Apply to this trial

Phase 3 Study of Teclistamab in Combination With Lenalidomide and Teclistamab Alone Versus Lenalidomide Alone in Participants With Newly Diagnosed Multiple Myeloma as Maintenance Therapy Following Autologous Stem Cell Transplantation

for Multiple Myeloma

Drug: Teclistamab

Sites in San Diego, Los Angeles +39 more locations

Sponsor: European Myeloma Network B.V.

Sex: All·Age: 18+

Code: NCT05243797·Phase 3·Recruiting·Listed Feb 2022

Apply to this trial

Naxitamab Added to Induction for Newly Diagnosed High-Risk Neuroblastoma

for Neuroblastoma

Sites in San Diego, Oakland +17 more locations

Sponsor: Giselle Sholler

Sex: All·Age: 12 Months - 21

Code: NCT05489887·Phase 2·Recruiting·Listed Aug 2022

Apply to this trial

Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial

for Anatomic Stage IV Breast Cancer AJCC v8

Sites in San Diego, La Jolla +56 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT06500481·Phase 3·Recruiting·Listed Jul 2024

Apply to this trial

Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer

for Fallopian Tube Endometrioid Adenocarcinoma

Drug: Bevacizumab

Sites in San Diego, La Jolla +643 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT06580314·Phase 3·Recruiting·Listed Aug 2024

Apply to this trial

Studying the Safety and Determining the Optimal Dose of Novobiocin in Patients With Tumors That Have Alterations in DNA Repair Genes

for Metastatic Malignant Solid Neoplasm

Sites in San Diego, La Jolla +16 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05687110·Phase 1·Recruiting·Listed Jan 2023

Apply to this trial

Testing the Combination of the Anti-cancer Drugs ZEN003694 (ZEN-3694) and Talazoparib in Patients With Advanced Solid Tumors, The ComBET Trial

for Advanced Malignant Solid Neoplasm

Sites in San Diego, La Jolla +21 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05327010·Phase 2·Recruiting·Listed Apr 2022

Apply to this trial

Project: Every Child for Younger Patients With Cancer

for Adrenal Gland Pheochromocytoma

Sites in San Diego, Orange +231 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 25

Code: NCT02402244·Recruiting·Listed Mar 2015

Apply to this trial

Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021)

for Recurrent World Health Organization (WHO) Grade II Glioma

Drug: Trametinib

Sites in San Diego, Los Angeles +13 more locations

Sponsor: University of California, San Francisco

Sex: All·Age: 1 - 25

Code: NCT04485559·Phase 1·Recruiting·Listed Jul 2020

Apply to this trial

Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

for Metastatic Malignant Neoplasm in the Lung

Sites in San Diego, Orange +209 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 50

Code: NCT05235165·Phase 3·Recruiting·Listed Feb 2022

Apply to this trial

Adding Dasatinib Or Venetoclax To Improve Responses In Children With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (ALL) Or Lymphoma (T-LLY) Or Mixed Phenotype Acute Leukemia (MPAL)

for T-cell Acute Lymphoblastic Leukemia

Drug: Venetoclax

Sites in San Diego +3 more locations

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 1 - 18

Code: NCT06390319·Phase 2·Recruiting·Listed Apr 2024

Apply to this trial

Identification of Necessary Information for Treatment Induction in Newly Diagnosed Acute Lymphoblastic Leukemia/Lymphoma

for Acute Lymphoblastic Leukemia

Sites in San Diego +4 more locations

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 1 - 18

Code: NCT06289673·Phase 4·Recruiting·Listed Mar 2024

Apply to this trial

Conventionally Fractionated vs. Hypofractionated Comprehensive Nodal Irradiation for Breast Cancer Using Pencil Beam Scanning Proton Therapy

for Breast Cancer

Sites in San Diego +8 more locations

Sponsor: Proton Collaborative Group

Sex: Female·Age: 19+

Code: NCT05856773·Phase 3·Recruiting·Listed May 2023

Apply to this trial

Early Detection of Advanced Adenomas and Colorectal Cancer

for Colorectal Cancer

Sites in San Diego & Monrovia

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06342440·Recruiting·Listed Apr 2024

Apply to this trial

International Registry for Men With Advanced Prostate Cancer (IRONMAN)

for Prostate Cancer

Sites in San Diego +34 more locations

Sponsor: Prostate Cancer Clinical Trials Consortium

Sex: Male·Age: 21+

Code: NCT03151629·Recruiting·Listed May 2017

Apply to this trial

Improving Survival for Metastatic Lobular Breast Cancer (PLUMB Registry)

for Metastatic Breast Cancer

Sites in San Diego, San Francisco +2 more locations

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT05964504·Recruiting·Listed Jul 2023

Apply to this trial

Personalized Antibody-Drug Conjugate Therapy Based on RNA and Protein Testing for the Treatment of Advanced or Metastatic Solid Tumors (The ADC MATCH Screening and Treatment Trial)

for Advanced Malignant Solid Neoplasm

Sites in San Diego, La Jolla +25 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06311214·Phase 2·Recruiting·Listed Mar 2024

Apply to this trial

Pediatric Precision Laboratory Advanced Neuroblastoma Therapy

for Neuroblastoma

Sites in San Diego, Oakland +18 more locations

Sponsor: Giselle Sholler

Sex: All·Age: Up to 22

Code: NCT02559778·Phase 2·Recruiting·Listed Sep 2015

Apply to this trial

Registry Study for Radiation Therapy Outcomes

for Neoplasms

Sites in San Diego +28 more locations

Sponsor: Proton Collaborative Group

Sex: All·Age: All ages

Code: NCT01255748·Recruiting·Listed Dec 2010

Apply to this trial

UCSD Image-Guided Cognitive-Sparing Radiosurgery for Brain Metastases

for Brain Metastases, Adult

1 location in San Diego

Sponsor: Jona Hattangadi-Gluth

Sex: All·Age: 18+

Code: NCT04343157·Phase 2·Recruiting·Listed Apr 2020

Apply to this trial

Longitudinal Prospective Study of Neurocognition & Neuroimaging in Primary BT Patients

for Primary Brain Tumor

1 location in San Diego

Sponsor: Jona Hattangadi-Gluth

Sex: All·Age: 18 - 99

Code: NCT05576103·Recruiting·Listed Oct 2022

Apply to this trial

Study of Revumenib, Azacitidine, and Venetoclax in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

for Refractory Acute Myeloid Leukemia

Drug: Venetoclax

Sites in San Diego +9 more locations

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 1 - 30

Code: NCT06177067·Phase 1·Recruiting·Listed Dec 2023

Apply to this trial

Surveillance Colonoscopy in Older Adults: The SurvOlderAdults Study

for Colorectal Cancer

Sites in San Diego & West Los Angeles

Sponsor: VA Office of Research and Development

Sex: All·Age: 75+

Code: NCT05994482·Recruiting·Listed Aug 2023

Apply to this trial

Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer

for Hematopoietic and Lymphatic System Neoplasm

Sites in San Diego, La Jolla +178 more locations

Sponsor: Children's Oncology Group

Sex: Female·Age: Up to 39

Code: NCT06513962·Phase 3·Recruiting·Listed Jul 2024

Apply to this trial

Conditions in Oncology (San Diego, CA)

Solid tumor· 20 Non-small cell lung cancer (NSCLC)· 12 Breast cancer· 10 Metastatic breast cancer· 9 Colorectal cancer· 8 Cancer (any)· 8 Prostate cancer· 7 Esophageal cancer· 6 Kidney cancer· 6 Ovarian cancer· 6 Pancreatic cancer· 5 Endometrial cancer· 5 Neuroblastoma· 5 Gastric cancer· 4 Metastatic prostate cancer· 4 Bladder cancer· 4 Cervical cancer· 4 Acute myeloid leukemia (AML)· 4 Leukemia (other)· 4 Fallopian tube cancer· 3 Glioma· 3 Acute lymphoblastic leukemia· 3 Hematologic malignancy· 3 Melanoma· 3 Head and neck cancer· 3 Osteosarcoma· 3 Pediatric cancer· 3 Triple-negative breast cancer· 2 Lung cancer· 2 Liver cancer· 2 Chronic lymphocytic leukemia (CLL)· 2 Myelodysplastic syndromes (MDS)· 2 Myelofibrosis· 2 Non-Hodgkin lymphoma· 2 Diffuse large B-cell lymphoma (DLBCL)· 2 Small lymphocytic lymphoma· 2 HER2-negative breast cancer· 1 Small cell lung cancer· 1 Metastatic colorectal cancer· 1 Colon cancer· 1 Rectal cancer· 1 Gastroesophageal junction cancer· 1 Biliary tract cancer· 1 Uterine cancer· 1 Glioblastoma· 1 Brain cancer· 1 Multiple myeloma· 1 Myeloproliferative neoplasm· 1 Hodgkin lymphoma· 1 Skin cancer· 1 Thyroid cancer· 1 Sarcoma· 1 Ewing sarcoma· 1 Rhabdomyosarcoma· 1 Mesothelioma· 1