Oncology Clinical Trials in San Diego, CA
As of September 2026, 106 paid clinical trials are recruiting for Oncology in San Diego, California. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in San Diego
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
107 clinical trials for Oncology
·Clear filters·Symbiotic-GU-06: A Study to Learn About PF-08634404 Alone or In Combination With Enfortumab Vedotin in Urothelial Cancer
Symbiotic-GU-08: A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer
A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.
Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer
A Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2
Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL
Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.
Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer
A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.
Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread
A Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression
Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)
A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)
Study of Rondecabtagene Autoleucel in Aggressive Large B-Cell Lymphoma
Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1
Study of Navtemadlin add-on to Ruxolitinib in JAK Inhibitor-Naïve Patients With Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib
Prospective Study to Assess a Diagnostic Aid for Cancer
Study to Assess the Efficacy and Safety of Rina-S in Participants With Non-small Cell Lung Cancer
Open-Label Phase 1/2 Study of NEO-811 in Subjects With Locally Advanced or Metastatic Non-Resectable Clear Cell Renal Cell Carcinoma
A Study to Evaluate the Effect of GDC-4198 Alone and in Combination With Giredestrant Versus Abemaciclib and Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive (ER+), Human Epidermal Growth Factor Receptor-Negative (HER2-) Breast Cancer
A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors
Pembrolizumab With or Without Maintenance Sacituzumab Tirumotecan (Sac-TMT; MK-2870) in Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) [MK-2870-023]
A Phase 2 Study to Evaluate the Effects of ASP5541 in Participants With Prostate Cancer
Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors
A Study of PHN-012 in Patients With Advanced Solid Tumors
Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors
BBO-11818 in Adult Subjects With KRAS Mutant Cancer
Phase 1/2 Study of PYX-201 in Combination With Pembrolizumab in Advanced Solid Tumors
Evexomostat Plus PI3K or AKT Inhibitor and Fulvestrant in Patients With a PI3K Alteration and HR+/Her2- Breast Cancer
A Phase 1/2 Study to Investigate CRB-701 in Solid Tumors
First-in-Human Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, as a Single Agent in Patients With Advanced Solid Tumors and in Combination With Endocrine Therapy +/- a CDK4/6 or CDK4 Inhibitor in Patients With Advanced Solid Tumors or Advanced Breast Cancer
A Study of STRO-004 in Adults With Refractory/Recurrent Metastatic Cancer
A Study of Rebecsinib for Patients With Relapsed/Refractory Secondary Acute Myeloid Leukemia or High Risk Myelofibrosis
A Feasibility Study to Evaluate the Safety of the TheraSphere Glioblastoma (GBM) Device in Patients With Recurrent GBM
Efficacy and Safety of the CG-100 Intraluminal Bypass Device
Study of Orally Administered MOMA-341 in Participants With Advanced or Metastatic Solid Tumors
ACE2016 in Adult Subjects With Locally Advanced or Metastatic Solid Tumors Expressing Epidermal Growth Factor Receptor (EGFR)
Pan-tumor MRD Study
ExoLuminate Study for Early Detection of Pancreatic Cancer
A Beta-only IL-2 ImmunoTherapY Study
Top Research Study Locations in San Diego
Researchers run research studies in San Diego, CA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of California San Diego | Anorexia Nervosa, Dementia, Vascular, Diabetes | 40 |
| University of California, San Diego | Femoral Fracture, Hiv, Nephrolithiasis | 40 |
| Rady Children's Hospital | Neuroblastoma, Acute Lymphoblastic Leukemia, Angelman Syndrome | 33 |
| VA San Diego Healthcare System, San Diego, CA | Stress Disorders, Post-Traumatic, Alcohol Use Disorder, Bipolar Disorder | 33 |
| Rady Children's Hospital - San Diego | Malignant Solid Neoplasm, Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia | 30 |
| San Diego State University | Depression, Diabetes Mellitus, Type 2, Obesity | 21 |
| UC San Diego Medical Center - Hillcrest | Metastatic Malignant Solid Neoplasm, Advanced Malignant Solid Neoplasm, Anatomic Stage IV Breast Cancer AJCC v8 | 21 |
| Kaiser Permanente-San Diego Zion | Breast Cancer, Adenocarcinoma of the Colon, Adenocarcinoma of the Rectum | 18 |
| Rady Children's Hospital San Diego | Acute Lymphoblastic Leukemia (ALL), Acute Myelogenous Leukemia (AML or ANLL), Autoimmune Diseases | 15 |
| Naval Medical Center San Diego | Attention Concentration Difficulty, Attention Impaired, Autism | 11 |
| Sharp Mary Birch Hospital for Women & Newborns | Infant, Newborn, Infant, Small for Gestational Age, Respiratory Distress Syndrome (Neonatal) | 11 |
| Artemis Institute for Clinical Research | Alcohol Use Disorder, Chronic Pain, Obesity | 10 |
| Scripps Health | Atrial Fibrillation, Biliary Tract Cancer, Bone Marrow Transplant Complications | 9 |
| UC San Diego | Anxiety Disorders, Bone Tumor, Breast Cancer | 9 |
| Acclaim Clinical Research | Acute Migraine, Atherosclerotic Cardiovascular Disease, COVID-19 SARS-CoV-2 Infection | 8 |
| GSK Investigational Site | Non-alcoholic Fatty Liver Disease, HIV Infections, Hypereosinophilic Syndrome | 7 |
| Medical Associates Research Group, Inc. | Crohn Disease, Colitis, Ulcerative, Liver Fibrosis | 7 |
| Sharp Memorial Hospital | Acral Lentiginous Melanoma, Acral Melanoma, Advanced Malignant Solid Neoplasm | 7 |
| University of California - San Diego | Delivery Complication, Hernia, Diaphragmatic, Hernia, Hiatal | 7 |
| VA San Diego Healthcare System | Depression, Anxiety Sensitivity, C. Diff Infection | 7 |
| West Dermatology Research Center | Laxity; Skin, Wrinkle, Facial Laxity | 7 |
| Kaiser Permanente-San Diego Mission | Adenocarcinoma of the Colon, Adenocarcinoma of the Rectum, Anatomic Stage IV Breast Cancer AJCC v8 | 6 |
| Naval Medical Center -San Diego | Adrenal Gland Pheochromocytoma, B Acute Lymphoblastic Leukemia, B Lymphoblastic Lymphoma | 6 |
| Neurocrine Clinical Site | Major Depressive Disorder, Schizophrenia, Bipolar Disorder | 6 |
| UC San Diego Health | Anxiety, Atrial Fibrillation (AF), Body Awareness | 6 |
Active & Upcoming Studies in San Diego (2026)
Recruiting trials in San Diego grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (151 active studies)
Neurology & pain (50 active studies)
- Mantram Repetition Versus Health Education for Veterans With PTSD and Chronic Pain · VA Office of Research and Development
- Durability of Yoga for Veterans With Low Back Pain · VA Office of Research and Development
Mental health & behavior (46 active studies)
- Optimizing CBSST With Executive Function Training for Schizophrenia (R33) · University of California, San Diego
- Supported Online Self-Help for Veterans With Depression in Primary Care · University of California, Los Angeles
Diabetes & metabolic (44 active studies)
- A Study of Orforglipron (LY3502970) Compared With Dulaglutide in Pediatric Participants With Type 2 Diabetes · Phase 3 · Eli Lilly and Company
- A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide · Phase 3 · Novo Nordisk A/S
Cardiovascular (39 active studies)
- A Prospective, Randomized Multicenter Clinical Trial of the TricValve® Transcatheter Bicaval Valve System in Subjects With Severe Tricuspid Regurgitation. · P+F Products + Features USA Inc.
- Atrial Fibrillation Among Patients With Hematologic Malignancies on Tyrosine Kinase Inhibitor Therapy · Tina Baykaner
Pediatric (21 active studies)
- Pressure Targeting During High Flow Therapy in Premature Infants · Phase 2 · University of Texas at Austin
- Supraglottic Airway for Resuscitation Trial · Children's Hospital of Philadelphia
HIV / STI (13 active studies)
- A Study to Evaluate the Safety and Antiviral Activity of Two Human Monoclonal Antibodies (VRC07-523LS and PGT121.414.LS) During Analytic Treatment Interruption in Participants Living With HIV Who Initiated ART During Acute/Early HIV-1 Infection · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
- A Study to Investigate Cabotegravir Ultra Long-Acting (CAB ULA) Plus Rilpivirine Ultra Long-Acting (RPV ULA) in Adults and Adolescents With HIV Who Are Virologically Suppressed · Phase 3 · ViiV Healthcare
Vaccines (9 active studies)
- Phase 1/2 Study of Respiratory Syncytial Virus and Human Metapneumovirus (RSV+HMPV) Vaccine Candidate in Adults 60 Years of Age and Older · Phase 1, Phase 2 · Sanofi
- A Study on the Safety and Immune Response of Investigational mRNA Seasonal Flu/COVID-19 Combination Vaccine in Adults · Phase 1 · GlaxoSmithKline
Eye & vision (1 active study)
- The Myelin Disorders Biorepository Project · Children's Hospital of Philadelphia
Common conditions studied in San Diego
- Obesity (15 active studies)
- Heart Failure (13 active studies)
- Depression (11 active studies)
- Breast Cancer (10 active studies)
- Major Depressive Disorder (10 active studies)
- Schizophrenia (10 active studies)
Leading research sponsors in San Diego
- University of California, San Diego
- VA Office of Research and Development
- San Diego State University
- National Cancer Institute (NCI)
- Pfizer
Frequently asked questions
How many paid clinical trials are currently recruiting in San Diego?
There are approximately 752 recruiting clinical trials in San Diego, California listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in San Diego pay participants?
Most recruiting trials in San Diego compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in San Diego?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in San Diego?
The most common conditions under active study in San Diego include Obesity (15), Heart Failure (13), Depression (11), Breast Cancer (10), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in San Diego?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in San Diego on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in San Diego?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in San Diego?
Recruiting research sites in San Diego include University of California San Diego, University of California, San Diego, Rady Children's Hospital, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in San Diego right now?
The largest active categories in San Diego are Cancer & tumors (151), Neurology & pain (50), Mental health & behavior (46). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.