A Study of PHN-012 in Patients With Advanced Solid Tumors
for Colon Cancer
Sites in San Diego, Los Angeles +9 more locations
Sponsor: Pheon Therapeutics
Sex: All·Age: 18+
Code: NCT07127874·Phase 1·Recruiting·Listed Aug 2025
Solid tumor Clinical Trials in San Diego, CA
As of August 2026, 19 paid clinical trials are recruiting for Solid tumor in San Diego, California. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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19 clinical trials for Solid tumor
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Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors
for Solid Tumor, Adult
Sites in San Diego, Duarte +17 more locations
Sponsor: TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)
Sex: All·Age: 18+
Code: NCT06625775·Phase 1·Recruiting·Listed Oct 2024
BBO-11818 in Adult Subjects With KRAS Mutant Cancer
for Non-Small Cell Lung Cancer
Sites in San Diego, Los Angeles +14 more locations
Sponsor: TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)
Sex: All·Age: 18+
Code: NCT06917079·Phase 1·Recruiting·Listed Apr 2025
Phase 1/2 Study of PYX-201 in Combination With Pembrolizumab in Advanced Solid Tumors
for Advanced Solid Tumors
Sites in San Diego, Santa Monica +9 more locations
Sponsor: Pyxis Oncology, Inc
Sex: All·Age: 18+
Code: NCT06795412·Phase 1, Phase 2·Recruiting·Listed Jan 2025
A Phase 1/2 Study to Investigate CRB-701 in Solid Tumors
for Solid Tumor, Adult
Sites in San Diego, Duarte +8 more locations
Sponsor: Corbus Pharmaceuticals Inc.
Sex: All·Age: 18+
Code: NCT06265727·Phase 1, Phase 2·Recruiting·Listed Feb 2024
First-in-Human Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, as a Single Agent in Patients With Advanced Solid Tumors and in Combination With Endocrine Therapy +/- a CDK4/6 or CDK4 Inhibitor in Patients With Advanced Solid Tumors or Advanced Breast Cancer
for PIK3CA Mutation
Sites in San Diego +22 more locations
Sponsor: Relay Therapeutics, Inc.
Sex: All·Age: 18+
Code: NCT05216432·Phase 1·Recruiting·Listed Jan 2022
Study of Orally Administered MOMA-341 in Participants With Advanced or Metastatic Solid Tumors
for Advanced Solid Tumor
Sites in San Diego +7 more locations
Sponsor: MOMA Therapeutics
Sex: All·Age: 18+
Code: NCT06974110·Phase 1·Recruiting·Listed May 2025
ACE2016 in Adult Subjects With Locally Advanced or Metastatic Solid Tumors Expressing Epidermal Growth Factor Receptor (EGFR)
for Locally Advanced Solid Tumor
Sites in San Diego +3 more locations
Sponsor: Acepodia Biotech, Inc.
Sex: All·Age: 18+
Code: NCT06415487·Phase 1·Recruiting·Listed May 2024
A Beta-only IL-2 ImmunoTherapY Study
for Advanced Solid Tumor
Sites in San Diego, Santa Monica +3 more locations
Sponsor: Medicenna Therapeutics, Inc.
Sex: All·Age: 18+
Code: NCT05086692·Phase 1, Phase 2·Recruiting·Listed Oct 2021
Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial
for Advanced Malignant Solid Neoplasm
Sites in San Diego, La Jolla +429 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: All ages
Code: NCT05564377·Phase 2·Recruiting·Listed Oct 2022
Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer
for Hematopoietic and Lymphatic System Neoplasm
Sites in San Diego, La Jolla +189 more locations
Sponsor: Children's Oncology Group
Sex: Female·Age: Up to 39
Code: NCT06513962·Phase 3·Recruiting·Listed Jul 2024
Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain
for Anatomic Stage IV Breast Cancer AJCC v8
Sites in San Diego, La Jolla +255 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT06500455·Phase 3·Recruiting·Listed Jul 2024
Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)
for Malignant Female Reproductive System Neoplasm
Sites in San Diego, La Jolla +176 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06126276·Phase 2·Recruiting·Listed Nov 2023
Project: Every Child for Younger Patients With Cancer
for Adrenal Gland Pheochromocytoma
Sites in San Diego, Orange +225 more locations
Sponsor: Children's Oncology Group
Sex: All·Age: Up to 25
Code: NCT02402244·Recruiting·Listed Mar 2015
Testing the Combination of the Anti-cancer Drugs ZEN003694 (ZEN-3694) and Talazoparib in Patients With Advanced Solid Tumors, The ComBET Trial
for Advanced Malignant Solid Neoplasm
Sites in San Diego, La Jolla +20 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT05327010·Phase 2·Recruiting·Listed Apr 2022
Studying the Safety and Determining the Optimal Dose of Novobiocin in Patients With Tumors That Have Alterations in DNA Repair Genes
for Metastatic Malignant Solid Neoplasm
Sites in San Diego, La Jolla +16 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT05687110·Phase 1·Recruiting·Listed Jan 2023
Personalized Antibody-Drug Conjugate Therapy Based on RNA and Protein Testing for the Treatment of Advanced or Metastatic Solid Tumors (The ADC MATCH Screening and Treatment Trial)
for Advanced Malignant Solid Neoplasm
Sites in San Diego, La Jolla +25 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06311214·Phase 2·Recruiting·Listed Mar 2024
A Culturally-Tailored Mobile Health and Social Media Physical Activity Intervention for Improving Physical Activity in Hispanic or Latino/Latina Adolescent and Young Adult Childhood Cancer Survivors, Walking Juntos Study
for Hematopoietic and Lymphatic System Neoplasm
Sites in San Diego, Long Beach +74 more locations
Sponsor: Children's Oncology Group
Sex: All·Age: 15 - 20
Code: NCT06410209·Phase 2·Recruiting·Listed May 2024
A Phase 1 Study of AB521 Monotherapy and Combination Therapies in Renal Cell Carcinoma and Other Solid Tumors
for Clear Cell Renal Cell Carcinoma
Sites in San Diego, Santa Monica +18 more locations
Sponsor: Arcus Biosciences, Inc.
Sex: All·Age: 18+
Code: NCT05536141·Phase 1·Recruiting·Listed Sep 2022
Top Research Study Locations in San Diego
Researchers run research studies in San Diego, CA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of California, San Diego | Femoral Fracture, Hiv, Nephrolithiasis | 41 |
| University of California San Diego | Anorexia Nervosa, Dementia, Vascular, Diabetes | 40 |
| Rady Children's Hospital | Neuroblastoma, Acute Lymphoblastic Leukemia, Angelman Syndrome | 33 |
| VA San Diego Healthcare System, San Diego, CA | Stress Disorders, Post-Traumatic, Alcohol Use Disorder, Bipolar Disorder | 33 |
| Rady Children's Hospital - San Diego | Malignant Solid Neoplasm, Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia | 30 |
| UC San Diego Medical Center - Hillcrest | Metastatic Malignant Solid Neoplasm, Advanced Malignant Solid Neoplasm, Anatomic Stage IV Breast Cancer AJCC v8 | 21 |
| San Diego State University | Depression, Diabetes Mellitus, Type 2, Obesity | 20 |
| Kaiser Permanente-San Diego Zion | Breast Cancer, Adenocarcinoma of the Colon, Adenocarcinoma of the Rectum | 18 |
| Rady Children's Hospital San Diego | Acute Lymphoblastic Leukemia (ALL), Acute Myelogenous Leukemia (AML or ANLL), Autoimmune Diseases | 15 |
| Naval Medical Center San Diego | Attention Concentration Difficulty, Attention Impaired, Autism | 11 |
| Sharp Mary Birch Hospital for Women & Newborns | Infant, Newborn, Infant, Small for Gestational Age, Respiratory Distress Syndrome (Neonatal) | 11 |
| Artemis Institute for Clinical Research | Alcohol Use Disorder, Chronic Pain, Obesity | 10 |
| Scripps Health | Atrial Fibrillation, Biliary Tract Cancer, Bone Marrow Transplant Complications | 9 |
| UC San Diego | Anxiety Disorders, Bone Tumor, Breast Cancer | 9 |
| Acclaim Clinical Research | Acute Migraine, Atherosclerotic Cardiovascular Disease, COVID-19 SARS-CoV-2 Infection | 8 |
| GSK Investigational Site | Non-alcoholic Fatty Liver Disease, HIV Infections, Hypereosinophilic Syndrome | 7 |
| Medical Associates Research Group, Inc. | Crohn Disease, Colitis, Ulcerative, Liver Fibrosis | 7 |
| Sharp Memorial Hospital | Acral Lentiginous Melanoma, Acral Melanoma, Advanced Malignant Solid Neoplasm | 7 |
| University of California - San Diego | Delivery Complication, Hernia, Diaphragmatic, Hernia, Hiatal | 7 |
| VA San Diego Healthcare System | Depression, Anxiety Sensitivity, C. Diff Infection | 7 |
| West Dermatology Research Center | Laxity; Skin, Wrinkle, Facial Laxity | 7 |
| Kaiser Permanente-San Diego Mission | Adenocarcinoma of the Colon, Adenocarcinoma of the Rectum, Anatomic Stage IV Breast Cancer AJCC v8 | 6 |
| Naval Medical Center -San Diego | Adrenal Gland Pheochromocytoma, B Acute Lymphoblastic Leukemia, B Lymphoblastic Lymphoma | 6 |
| Neurocrine Clinical Site | Major Depressive Disorder, Schizophrenia, Bipolar Disorder | 6 |
| UCSD | Atrial Fibrillation (AF), Down Syndrome, Fetal Aneuploidy | 5 |
Active & Upcoming Studies in San Diego (2026)
Recruiting trials in San Diego grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (151 active studies)
Neurology & pain (50 active studies)
- Mantram Repetition Versus Health Education for Veterans With PTSD and Chronic Pain · VA Office of Research and Development
- Durability of Yoga for Veterans With Low Back Pain · VA Office of Research and Development
Mental health & behavior (46 active studies)
- Optimizing CBSST With Executive Function Training for Schizophrenia (R33) · University of California, San Diego
- Supported Online Self-Help for Veterans With Depression in Primary Care · University of California, Los Angeles
Diabetes & metabolic (46 active studies)
- A Study of Orforglipron (LY3502970) Compared With Dulaglutide in Pediatric Participants With Type 2 Diabetes · Phase 3 · Eli Lilly and Company
- A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide · Phase 3 · Novo Nordisk A/S
Cardiovascular (39 active studies)
- A Prospective, Randomized Multicenter Clinical Trial of the TricValve® Transcatheter Bicaval Valve System in Subjects With Severe Tricuspid Regurgitation. · P+F Products + Features USA Inc.
- Atrial Fibrillation Among Patients With Hematologic Malignancies on Tyrosine Kinase Inhibitor Therapy · Tina Baykaner
Pediatric (21 active studies)
- Pressure Targeting During High Flow Therapy in Premature Infants · Phase 2 · University of Texas at Austin
- Supraglottic Airway for Resuscitation Trial · Children's Hospital of Philadelphia
HIV / STI (13 active studies)
- A Study to Evaluate the Safety and Antiviral Activity of Two Human Monoclonal Antibodies (VRC07-523LS and PGT121.414.LS) During Analytic Treatment Interruption in Participants Living With HIV Who Initiated ART During Acute/Early HIV-1 Infection · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
- A Study to Investigate Cabotegravir Ultra Long-Acting (CAB ULA) Plus Rilpivirine Ultra Long-Acting (RPV ULA) in Adults and Adolescents With HIV Who Are Virologically Suppressed · Phase 3 · ViiV Healthcare
Vaccines (9 active studies)
- Phase 1/2 Study of Respiratory Syncytial Virus and Human Metapneumovirus (RSV+HMPV) Vaccine Candidate in Adults 60 Years of Age and Older · Phase 1, Phase 2 · Sanofi
- A Study on the Safety and Immune Response of Investigational mRNA Seasonal Flu/COVID-19 Combination Vaccine in Adults · Phase 1 · GlaxoSmithKline
Eye & vision (1 active study)
- The Myelin Disorders Biorepository Project · Children's Hospital of Philadelphia
Common conditions studied in San Diego
- Obesity (16 active studies)
- Heart Failure (13 active studies)
- Depression (12 active studies)
- Breast Cancer (10 active studies)
- Major Depressive Disorder (10 active studies)
- Schizophrenia (10 active studies)
Leading research sponsors in San Diego
- University of California, San Diego
- VA Office of Research and Development
- San Diego State University
- National Cancer Institute (NCI)
- Pfizer
Frequently asked questions
How many paid clinical trials are currently recruiting in San Diego?
There are approximately 758 recruiting clinical trials in San Diego, California listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in San Diego pay participants?
Most recruiting trials in San Diego compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in San Diego?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in San Diego?
The most common conditions under active study in San Diego include Obesity (16), Heart Failure (13), Depression (12), Breast Cancer (10), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in San Diego?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in San Diego on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in San Diego?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in San Diego?
Recruiting research sites in San Diego include University of California, San Diego, University of California San Diego, Rady Children's Hospital, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in San Diego right now?
The largest active categories in San Diego are Cancer & tumors (151), Neurology & pain (50), Mental health & behavior (46). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
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