Paid Clinical Trials in South Carolina

South Carolina has 1,277 paid clinical trials enrolling now across cities including Charleston, Greenville and Columbia. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 16, 2026.

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1,277 clinical trials

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Trial Investigating Visugromab in Combination With Immunochemotherapy in 1L Treatment of Participants With Metastatic NSCLC

for Metastatic Non-Squamous Non-Small Cell Lung Cancer

6 locations incl. Birmingham

Sponsor: CatalYm GmbH

Sex: All·Age: 18+

Code: NCT07098988·Phase 2·Recruiting

Apply to this trial

WRAP North America

for Venous Stenosis

11 locations incl. Dothan

Sponsor: Merit Medical Systems, Inc.

Sex: All·Age: 18+

Code: NCT06807099·Recruiting

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A Phase IIb Ensifentrine-glycopyrrolate Fixed-dose Combination Dose Ranging Study in Subjects With COPD

for Chronic Obstructive Pulmonary Disease

57 locations incl. Dothan

Sponsor: Verona Pharma, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA

Sex: All·Age: 40 - 80

Code: NCT07016412·Phase 2·Recruiting

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A Study to Learn About Medicine Called Ritlecitinib in Children Aged Between 6 to 12 Years With Severe Alopecia Areata

for Severe Alopecia Areata

Drug: Ritlecitinib

29 locations incl. Encinitas

Sponsor: Pfizer

Sex: All·Age: 6 - 11

Code: NCT07029711·Phase 3·Recruiting

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A Clinical Study of MK-8527 to Prevent Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8527-011)

for Human Immunodeficiency Virus (HIV)

23 locations incl. Birmingham

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 16+·Accepts healthy volunteers

Code: NCT07044297·Phase 3·Recruiting

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A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PEAK

for Macular Edema Secondary to Inflammation

55 locations incl. Phoenix

Sponsor: Kodiak Sciences Inc

Sex: All·Age: 18+

Code: NCT06990399·Phase 3·Recruiting

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Efficacy and Safety of 186 mcg of OPN-375 Nasal Spray Twice a Day (BID) in Adolescents With Chronic Rhinosinusitis Without Nasal Polyps

for Chronic Rhinosinusitis Without Nasal Polyps

21 locations incl. Gilbert

Sponsor: Optinose US Inc.

Sex: All·Age: 12 - 17

Code: NCT06850805·Phase 3·Recruiting

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A Study to Learn More About How Risankizumab Works in Young Participants With Ulcerative Colitis

for Ulcerative Colitis

Drug: Risankizumab

11 locations incl. Phoenix

Sponsor: AbbVie

Sex: All·Age: 2 - 17

Code: NCT07071519·Phase 3·Recruiting

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Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

for Atherosclerotic Cardiovascular Disease

139 locations incl. Daphne

Sponsor: Amgen

Sex: All·Age: 45 - 99

Code: NCT07037433·Phase 3·Recruiting

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Safety and Efficacy of VDPHL01 in Females With Androgenetic Alopecia (AGA)

for Androgenetic Alopecia (AGA)

71 locations incl. Birmingham

Sponsor: Veradermics, Inc.

Sex: Female·Age: 18 - 65

Code: NCT07146022·Phase 3·Recruiting

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A Study of the Medicine Called Abrocitinib in Children 6 to Less Than 12 Years of Age With Moderate-to-Severe Eczema

for Eczema

10 locations incl. Birmingham

Sponsor: Pfizer

Sex: All·Age: 6 - 11

Code: NCT06807268·Phase 3·Recruiting

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Monitoring & Mitigation of Neurologic Injuries to Optimize Resilience After Repetitive Head Impacts

for Head Injuries

3 locations incl. Amherst

Sponsor: University of Rochester

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06810193·Enrolling By Invitation

Efficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis.

for Relapsing Multiple Sclerosis

Drug: Remibrutinib

38 locations incl. Scottsdale

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 40 - 70

Code: NCT06846281·Phase 3·Recruiting

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Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention

for Percutaneous Coronary Intervention

Drug: Inclisiran

102 locations incl. Alexander City

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT06909565·Phase 4·Recruiting

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EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

for Diabetes Mellitus, Type 2

Drug: Empagliflozin

216 locations incl. Anniston

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT07064473·Phase 3·Recruiting

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Single Intravitreal (IVT) Injection of 4D-150 in Patients With Macular Neovascularization Secondary to Age-Related Macular Degeneration

for Neovascular Age-Related Macular Degeneration (nAMD)

54 locations incl. Scottsdale

Sponsor: 4D Molecular Therapeutics

Sex: All·Age: 50+

Code: NCT07064759·Phase 3·Recruiting

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DB-1311 in Combination With BNT327 or DB-1305 in Advanced/Metastatic Solid Tumors

for Solid Tumors

15 locations incl. Los Angeles

Sponsor: DualityBio Inc.

Sex: All·Age: 18+

Code: NCT06953089·Phase 2·Recruiting

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Testing the Addition of an Anti-Cancer Drug, Gemcitabine, to Usual Treatment (BCG Alone) in People Whose Non-Muscle Invasive Bladder Cancer (NMIBC) Came Back After Prior BCG Therapy

for Recurrent Non-Muscle Invasive Bladder Carcinoma

56 locations incl. Birmingham

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT07000084·Phase 3·Recruiting

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A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PINNACLE

for Macular Edema Secondary to Inflammation

55 locations incl. Phoenix

Sponsor: Kodiak Sciences Inc

Sex: All·Age: 18+

Code: NCT06996080·Phase 3·Recruiting

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Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve System (FASTR-II) (IDE-G210258)

for Acute Decompensated Heart Failure

37 locations incl. Irvine

Sponsor: Reprieve Cardiovascular, Inc

Sex: All·Age: 22+

Code: NCT06898515·Phase 3·Recruiting

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Real-world Experience Using Nemolizumab in the Treatment of Moderate-to-Severe Atopic Dermatitis in Adolescents & Adults

for Atopic Dermatitis

Drug: Nemolizumab

59 locations incl. Birmingham

Sponsor: Galderma R&D

Sex: All·Age: 12+

Code: NCT06988605·Recruiting

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A Study to Evaluate the SENSE Device's Ability to Detect TBI

for Traumatic Brain Injury

6 locations incl. Gainesville

Sponsor: Sense Diagnostics, LLC

Sex: All·Age: 22+·Accepts healthy volunteers

Code: NCT06828107·Recruiting

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A Study to Evaluate Efficacy of Remibrutinib Compared to Dupilumab at Early Timepoints in Adults With Chronic Spontaneous Urticaria Inadequately Controlled by Second Generation H1-antihistamines

for Chronic Spontaneous Urticaria (CSU)

Drug: Remibrutinib

128 locations incl. Birmingham

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06868212·Phase 3·Recruiting

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A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1)

for Alzheimer Disease

Drug: KarXT

40 locations incl. Scottsdale

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 55 - 90

Code: NCT07011732·Phase 3·Recruiting

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ELEVATE-HFpEF Clinical Study

for Heart Failure With Preserved Ejection Fraction (HFpEF)

25 locations incl. Phoenix

Sponsor: Medtronic Cardiac Rhythm and Heart Failure

Sex: All·Age: 40+

Code: NCT06678841·Recruiting

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AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.

for Refractory Rheumatoid Arthritis (RA)

Drug: Rituximab

31 locations incl. Tuscaloosa

Sponsor: Artiva Biotherapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06991114·Phase 2·Recruiting

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AFO Prescription to Optimize Post-Stroke Function

for Ankle Foot Orthosis (AFO)

4 locations incl. Downey

Sponsor: University of Texas at Austin

Sex: All·Age: 18+

Code: NCT06692686·Recruiting

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An Open-label Study of JSB462 (Luxdegalutamide) in Combination With Abiraterone in Adult Male Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)

for Metastatic Hormone-sensitive Prostate Cancer

Drug: JSB462

21 locations incl. La Jolla

Sponsor: Novartis Pharmaceuticals

Sex: Male·Age: 18+

Code: NCT06991556·Phase 2·Recruiting

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Nonhealing Diabetic Foot Ulcers Treated With Standard of Care (SOC) Alone or Standard of Care and Amnion-Intermediate-Chorion (AIC)

for Diabetic Foot Ulcer

8 locations incl. Santa Rosa

Sponsor: Cellution Biologics

Sex: All·Age: 18+

Code: NCT07014176·Phase 4·Recruiting

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TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

for Transthyretin Amyloidosis With Cardiomyopathy

Drug: Nucresiran

39 locations incl. La Jolla

Sponsor: Alnylam Pharmaceuticals

Sex: All·Age: 18 - 85

Code: NCT07052903·Phase 3·Recruiting

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Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies

for Alzheimers Disease

68 locations incl. Birmingham

Sponsor: Hoffmann-La Roche

Sex: All·Age: 50 - 90

Code: NCT07177352·Phase 3·Recruiting

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Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC

for Prostate Cancer

25 locations incl. Palo Alto

Sponsor: Novartis Pharmaceuticals

Sex: Male·Age: 18 - 100

Code: NCT06855277·Phase 3·Recruiting

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Longitudinal Screening for Financial Hardship to Improve Outcomes in Patients With Advanced Cancer

for Advanced Cancer

6 locations incl. Phoenix

Sponsor: Alliance Foundation Trials, LLC.

Sex: All·Age: 21+

Code: NCT06963723·Recruiting

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Neuromodulation + Prolonged Exposure Therapy: Evaluation of a Technology-Enhanced, Integrated Treatment for Pain and PTSD

for Chronic Pain

2 locations incl. Charleston

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: 21+

Code: NCT07116109·Recruiting

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A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

for Breast Neoplasms

53 locations incl. Gilbert

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06966700·Phase 3·Recruiting

Apply to this trial

E-Mindfulness Approaches for Living After Breast Cancer

for Breast Cancer

332 locations incl. Phoenix

Sponsor: NRG Oncology

Sex: All·Age: 18 - 50

Code: NCT06748222·Phase 3·Recruiting

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Efficacy and Safety of TYRA-300 in Participants With FGFR3 Altered Low Grade, Intermediate Risk Non-Muscle Invasive Bladder Cancer

for Low-grade NMIBC

28 locations incl. Homewood

Sponsor: Tyra Biosciences, Inc

Sex: All·Age: 18+

Code: NCT06995677·Phase 2·Recruiting

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Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled Study

for Moderate Aortic Valve Stenosis

Drug: Ataciguat

66 locations incl. Birmingham

Sponsor: Kardigan, Inc.

Sex: All·Age: 50+

Code: NCT07001800·Phase 2, Phase 3·Recruiting

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A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease

for Chronic Obstructive Pulmonary Disease (COPD)

Drug: AZD6793

86 locations incl. Birmingham

Sponsor: AstraZeneca

Sex: All·Age: 40+

Code: NCT07082738·Phase 2·Recruiting

Apply to this trial

Fueling Strong Hearts for a Strong South Carolina

for Stroke

1 location in Florence

Sponsor: Clemson University

Sex: All·Age: 45 - 80

Code: NCT07140952·Recruiting

Apply to this trial