Paid Clinical Trials in South Carolina

South Carolina has 1,217 paid clinical trials enrolling now across cities including Charleston, Greenville and Columbia. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 14, 2026.

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1,101 clinical trials

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A Clinical Study of Novel Pneumococcal Vaccine V118C in Children (V118C-002)

for Pneumococcal Infection

Sites in Greenville, Spartanburg +12 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 2 Months - 15 Months·Accepts healthy volunteers

Code: NCT07300267·Phase 1·Recruiting·Listed Dec 2025

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A Study to Evaluate TAR-210 Versus Intravesical Chemotherapy Treatment in Participants With High Risk Non-Muscle-Invasive Bladder Cancer

for Non-Muscle Invasive Bladder Neoplasms

Sites in Myrtle Beach +23 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06919965·Phase 3·Recruiting·Listed Apr 2025

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A Phase 2/3 Study of Osivelotor in Adult and Adolescent Participants With SCD

for Sickle Cell Disease

Sites in Greenville, Greer +33 more locations

Sponsor: Pfizer

Sex: All·Age: 12+

Code: NCT05431088·Phase 2, Phase 3·Recruiting·Listed Jun 2022

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A Study Observing Everyday Effectiveness and Safety of the Drug Elafibranor in Participants With Primary Biliary Cholangitis Who Are Receiving Ongoing Treatment

for Primary Biliary Cholangitis

Drug: Elafibranor

Sites in Charleston +18 more locations

Sponsor: Ipsen

Sex: All·Age: All ages

Code: NCT06447168·Recruiting·Listed Jun 2024

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A Study of Dupilumab in Small Children With an Allergic Condition of the Esophagus (Food Pipe): Eosinophilic Esophagitis

for Eosinophilic Esophagitis (EoE)

Drug: Dupilumab

Sites in Charleston +12 more locations

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 6 Months - 6

Code: NCT07112378·Phase 3·Recruiting·Listed Aug 2025

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A Study to Learn More About How Risankizumab Works in Young Participants With Ulcerative Colitis

for Ulcerative Colitis

Drug: Risankizumab

Sites in Greenville +11 more locations

Sponsor: AbbVie

Sex: All·Age: 2 - 17

Code: NCT07071519·Phase 3·Recruiting·Listed Jul 2025

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The Golazo® Peripheral Atherectomy System for a Safe and Effective Atherectomy (GREAT Trial)

for Peripheral Arterial Disease

Sites in Spartanburg +16 more locations

Sponsor: Nipro Vascular Innovations Americas, Inc

Sex: All·Age: 18+

Code: NCT06321575·Recruiting·Listed Mar 2024

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Sacral Neuromodulation for Male Overactive Bladder (MOAB)

for Overactive Bladder

Sites in North Charleston +19 more locations

Sponsor: Axonics, Inc.

Sex: Male·Age: 18+

Code: NCT06511141·Recruiting·Listed Jul 2024

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A Study to Test Whether Nerandomilast Can Help Slow Down Changes in the Lung in People With a Family History of Pulmonary Fibrosis

for Familial Pulmonary Fibrosis

Drug: Nerandomilast

Sites in Charleston +12 more locations

Sponsor: Boehringer Ingelheim

Sex: All·Age: 40+

Code: NCT07201922·Phase 3·Recruiting·Listed Oct 2025

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A Study of Zasocitinib in Adults With Nonsegmental Vitiligo

for Nonsegmental Vitiligo

Drug: Zasocitinib

Sites in Charleston +20 more locations

Sponsor: Takeda

Sex: All·Age: 18 - 75

Code: NCT07108283·Phase 2·Recruiting·Listed Aug 2025

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A Study of JNJ-88549968 for the Treatment of Calreticulin (CALR)-Mutated Myeloproliferative Neoplasms

for Neoplasms

Sites in Greenville +14 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06150157·Phase 1·Recruiting·Listed Nov 2023

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Safety, Pharmacokinetics, and Efficacy of AI-081, a Bispecific Antibody for PD-1 And VEGF in Advanced Solid Tumors

for Advanced Solid Tumor

Drug: AI-081

Sites in Greenville +20 more locations

Sponsor: OncoC4, Inc.

Sex: All·Age: 18+

Code: NCT06635785·Phase 1, Phase 2·Recruiting·Listed Oct 2024

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Study of HLD-0915 (JNJ-101556143) in Patients With Metastatic Prostate Cancer

for Metastatic Prostate Cancer

Sites in Myrtle Beach +16 more locations

Sponsor: Janssen Research & Development, LLC

Sex: Male·Age: 18+

Code: NCT06800313·Phase 1, Phase 2·Recruiting·Listed Jan 2025

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Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)

for Treatment Resistant Depression

Sites in Charleston +24 more locations

Sponsor: Abbott Medical Devices

Sex: All·Age: 22 - 70

Code: NCT06423430·Recruiting·Listed May 2024

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Total Shoulder Arthroplasty Multi-Center Registry

for Shoulder Arthroplasty

Sites in Greenville +15 more locations

Sponsor: Arthrex, Inc.

Sex: All·Age: 18 - 100

Code: NCT03511586·Recruiting·Listed Apr 2018

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A Study of FG-3246 in Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC)

for Metastatic Castration-Resistant Prostate Cancer

Sites in Myrtle Beach +22 more locations

Sponsor: Kyntra Bio

Sex: Male·Age: 18+

Code: NCT06842498·Phase 2·Recruiting·Listed Feb 2025

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A Study of Orelabrutinib in Patients With Primary Progressive Multiple Sclerosis

for Multiple Sclerosis (MS) Primary Progressive

Sites in Greenville +15 more locations

Sponsor: Zenas BioPharma (USA), LLC

Sex: All·Age: 18 - 60

Code: NCT07067463·Phase 3·Recruiting·Listed Jul 2025

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A Study of the Medicine Called Abrocitinib in Children 6 to Less Than 12 Years of Age With Moderate-to-Severe Eczema

for Eczema

Sites in Charleston, Greenville +11 more locations

Sponsor: Pfizer

Sex: All·Age: 6 - 11

Code: NCT06807268·Phase 3·Recruiting·Listed Feb 2025

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A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction

for Left Ventricular Systolic Dysfunction

Drug: Finerenone

Sites in North Charleston +21 more locations

Sponsor: Bayer

Sex: All·Age: Up to 18

Code: NCT07192952·Phase 3·Recruiting·Listed Sep 2025

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Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in Participants With Generalized Myasthenia Gravis (MyClad)

for Generalized Myasthenia Gravis

Sites in Charleston +18 more locations

Sponsor: Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany

Sex: All·Age: 18+

Code: NCT06463587·Phase 3·Recruiting·Listed Jun 2024

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Evaluation of Treatment Satisfaction and KarXT Utilization Registry (RESKU)

for Schizophrenia

Drug: KarXT

Sites in Fort Mill +16 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07101094·Recruiting·Listed Aug 2025

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The ArtixASCEND Study

for Acute Lower Limb Arterial Occlusion

Sites in Spartanburg, Myrtle Beach +18 more locations

Sponsor: Inari Medical

Sex: All·Age: 18+

Code: NCT07135895·Recruiting·Listed Aug 2025

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RevCore for In Stent Thrombosis

for In-stent Thrombosis

Sites in Spartanburg +15 more locations

Sponsor: Inari Medical

Sex: All·Age: 18+

Code: NCT06394739·Recruiting·Listed May 2024

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RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus

for Systemic Lupus Erythematosus

Sites in Charleston +17 more locations

Sponsor: Cabaletta Bio

Sex: All·Age: 18 - 65

Code: NCT06121297·Phase 1, Phase 2·Recruiting·Listed Nov 2023

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Pivotal Study of the Velocity™ pAVF System

for Chronic Kidney Disease

Sites in Orangeburg +12 more locations

Sponsor: Venova Medical

Sex: All·Age: 18 - 80

Code: NCT07153939·Recruiting·Listed Sep 2025

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A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease

for Anemia, Sickle Cell

Sites in Greenville +17 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06481306·Phase 1, Phase 2·Recruiting·Listed Jul 2024

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A Study of an MMSET Inhibitor in Patients With Relapsed and Refractory Multiple Myeloma

for Multiple Myeloma

Sites in Charleston +16 more locations

Sponsor: K36 Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05651932·Phase 1·Recruiting·Listed Dec 2022

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A Long-term Follow-up Study in Patients Who Received BEAM-101

for Hemoglobinopathy

Sites in Charleston +16 more locations

Sponsor: Beam Therapeutics Inc.

Sex: All·Age: 14 - 37

Code: NCT07373639·Recruiting·Listed Jan 2026

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A Phase 2 Study to Evaluate the Effects of ASP5541 in Participants With Prostate Cancer

for Prostate Cancer

Sites in Myrtle Beach +11 more locations

Sponsor: Astellas Pharma Global Development, Inc.

Sex: Male·Age: 18+

Code: NCT07005154·Phase 2·Recruiting·Listed Jun 2025

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A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension

for Uncontrolled Hypertension

Sites in Charleston +23 more locations

Sponsor: Retension Pharmaceuticals. Inc.

Sex: All·Age: 18 - 70

Code: NCT07142356·Phase 2·Recruiting·Listed Aug 2025

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A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors

for Metastatic Solid Tumor

Sites in Greenville +17 more locations

Sponsor: Coherus Oncology, Inc.

Sex: All·Age: 18+

Code: NCT06657144·Phase 1·Recruiting·Listed Oct 2024

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Efficacy and Safety of Zanidatamab With Standard-of-care Therapy Against Standard-of-care Therapy for Advanced HER2-positive Biliary Tract Cancer

for Biliary Tract Cancer

Sites in Greenville +12 more locations

Sponsor: Jazz Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06282575·Phase 3·Recruiting·Listed Feb 2024

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Study of ORIC-114 in Patients With Advanced Solid Tumors Harboring an EGFR or HER2 Alteration

for Solid Tumors

Sites in Spartanburg +16 more locations

Sponsor: ORIC Pharmaceuticals

Sex: All·Age: 18+

Code: NCT05315700·Phase 1, Phase 2·Recruiting·Listed Apr 2022

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A Phase 2 Study of LTI-03 in Patients With Idiopathic Pulmonary Fibrosis

for Idiopathic Pulmonary Fibrosis (IPF)

Sites in Charleston +18 more locations

Sponsor: Rein Therapeutics

Sex: All·Age: 40+

Code: NCT06968845·Phase 2·Recruiting·Listed May 2025

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Study to Evaluate ARINA-1 in the Prevention of Bronchiolitis Obliterans Progression in Participants With Bilateral Lung Transplant

for Pre-Bronchiolitis Obliterans Syndrome

Sites in Charleston +19 more locations

Sponsor: Renovion, Inc.

Sex: All·Age: 18 - 75

Code: NCT05654922·Phase 3·Recruiting·Listed Dec 2022

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A Study of Suvorexant (MK-4305) for the Treatment of Insomnia Disorder in Participants With Opioid Use Disorder (MK-4305-098)

for Insomnia

Sites in Charleston +12 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18 - 70

Code: NCT06655883·Phase 3·Recruiting·Listed Oct 2024

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Post Approval Study of Liposorber LA-15 System for the Treatment of Focal Segmental Glomerulosclerosis in Children

for Focal Segmental Glomerulosclerosis

Sites in Charleston +9 more locations

Sponsor: Kaneka Medical America LLC

Sex: All·Age: Up to 21

Code: NCT02235857·Recruiting·Listed Sep 2014

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The Efficacy and Safety of Rilzabrutinib in Participants Aged 10 to 65 Years With Sickle-cell Disease

for Sickle Cell Disease

Sites in Greenville +15 more locations

Sponsor: Sanofi

Sex: All·Age: 10 - 65

Code: NCT06975865·Phase 3·Recruiting·Listed May 2025

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A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction

for Left Ventricular Systolic Dysfunction

Drug: Finerenone

Sites in North Charleston +21 more locations

Sponsor: Bayer

Sex: All·Age: 6 Months - 17

Code: NCT07188805·Phase 3·Recruiting·Listed Sep 2025

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A Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis or Crohn's Disease

for Ulcerative Colitis

Sites in North Charleston +5 more locations

Sponsor: Takeda

Sex: All·Age: 2 - 17

Code: NCT06100289·Phase 3·Recruiting·Listed Oct 2023

Apply to this trial