Paid Clinical Trials in South Carolina

South Carolina has 1,226 paid clinical trials enrolling now across cities including Charleston, Greenville and Columbia. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 31, 2026.

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1,109 clinical trials

AMAZE 1: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Lose Weight

for Obesity

Drug: NNC0487-0111

Sites in Charleston, North Charleston +20 more locations

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07339423·Phase 3·Recruiting·Listed Jan 2026

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A Trial of TAK-861 for the Treatment of Narcolepsy With Cataplexy

for Narcolepsy Type 1 (NT1)

Sites in Columbia +10 more locations

Sponsor: Takeda

Sex: All·Age: 16 - 70

Code: NCT07363720·Phase 3·Recruiting·Listed Jan 2026

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Lot-to-lot Consistency Study of a 21-valent Pneumococcal Conjugate Vaccine in Healthy Infants From 2 Months of Age

for Pneumococcal Immunization

Sites in Charleston, Spartanburg +11 more locations

Sponsor: Sanofi

Sex: All·Age: 42 Days - 89 Days·Accepts healthy volunteers

Code: NCT07348692·Phase 3·Recruiting·Listed Jan 2026

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A Study to Investigate GB-0895 Adjunctive Therapy in Adults and Adolescents With Severe Uncontrolled Asthma (SOLAIRIA-2)

for Severe Asthma

Drug: GB-0895

Sites in Rock Hill +16 more locations

Sponsor: Generate Biomedicines

Sex: All·Age: 12 - 80

Code: NCT07359846·Phase 3·Recruiting·Listed Jan 2026

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Pivotal Study of the SUpira System in Patients Undergoing High-Risk Percutaneous COronaRy InTervention (HRPCI)

for Coronary Artery Disease

Sites in Columbia +18 more locations

Sponsor: Supira Medical

Sex: All·Age: 18 - 90

Code: NCT07296744·Recruiting·Listed Dec 2025

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Horizon 360 Protocol for the Treatment of Paroxysmal Atrial Fibrillation With the Sphere-360™ Catheter and Affera™ Mapping and Ablation System (Horizon 360)

for Paroxysmal AF

Sites in Charleston +23 more locations

Sponsor: Medtronic Cardiac Ablation Solutions

Sex: All·Age: 18 - 80

Code: NCT07308847·Recruiting·Listed Dec 2025

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AURN001 Efficacy in Participants With Corneal Edema Secondary to Corneal Endothelial Dysfunction

for Corneal Edema

Sites in Ladson +11 more locations

Sponsor: Aurion Biotech

Sex: All·Age: 18+

Code: NCT07368959·Phase 3·Recruiting·Listed Jan 2026

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A Study to Compare the Efficacy and Safety of BMS-986353 (Zolacabtagene- Autoleucel / Zola-cel), CD19-CAR T Cells, Versus Standard of Care in Participants With Active Systemic Sclerosis

for Systemic Sclerosis

Drug: BMS-986353

Sites in Charleston +16 more locations

Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All·Age: 16+

Code: NCT07335562·Phase 3·Recruiting·Listed Jan 2026

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A Study of Orelabrutinib in Patients With Secondary Progressive Multiple Sclerosis

for Secondary Progressive Multiple Sclerosis

Sites in Greenville +17 more locations

Sponsor: Zenas BioPharma (USA), LLC

Sex: All·Age: 18 - 60

Code: NCT07299019·Phase 3·Recruiting·Listed Dec 2025

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Open-Label Phase 1/2 Study of NEO-811 in Subjects With Locally Advanced or Metastatic Non-Resectable Clear Cell Renal Cell Carcinoma

for Clear Cell Renal Cell Carcinoma

Sites in Myrtle Beach +10 more locations

Sponsor: Neomorph, Inc

Sex: All·Age: 18+

Code: NCT07300241·Phase 1·Recruiting·Listed Dec 2025

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A Study to Evaluate the Safety, Tolerability, and Efficacy of Pumitamig Alone or in Combination With Ipilimumab or Cabozantinib in Participants With Advanced Renal Cell Carcinoma (RCC) (ROSETTA RCC-208)

for Advanced Renal Cell Carcinoma (RCC)

Drug: Cabozantinib

Sites in Charleston, Myrtle Beach +15 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07293351·Phase 1, Phase 2·Recruiting·Listed Dec 2025

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Efficacy and Safety of Ribupatide in Participants Living With Obesity or Overweight With Weight-Related Comorbidities Who Do Not Have Diabetes

for Obesity

Sites in Mauldin +23 more locations

Sponsor: Kailera

Sex: All·Age: 18+

Code: NCT07284875·Phase 3·Recruiting·Listed Dec 2025

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A Long-Term Study of Zasocitinib in Children and Teenagers With Plaque Psoriasis

for Plaque Psoriasis

Drug: Zasocitinib

Sites in Charleston +10 more locations

Sponsor: Takeda

Sex: All·Age: 4 - 17

Code: NCT07250802·Phase 3·Recruiting·Listed Nov 2025

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A Study of Praliciguat in Participants With Focal Segmental Glomerulosclerosis (FSGS)

for Focal Segmental Glomerulosclerosis

Sites in Goose Creek +21 more locations

Sponsor: Akebia Therapeutics

Sex: All·Age: 18+

Code: NCT07268638·Phase 2·Recruiting·Listed Dec 2025

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A Clinical Study of Novel Pneumococcal Vaccine V118C in Children (V118C-002)

for Pneumococcal Infection

Sites in Greenville, Spartanburg +12 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 2 Months - 15 Months·Accepts healthy volunteers

Code: NCT07300267·Phase 1·Recruiting·Listed Dec 2025

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Phase III Study to Assess the Safety and Efficacy of SL1002 for Osteoarthritis Knee Pain

for Osteoarthritis Knee Pain

Sites in Charleston, Greenville +19 more locations

Sponsor: Saol Therapeutics Inc

Sex: All·Age: 40+

Code: NCT07226258·Phase 3·Recruiting·Listed Nov 2025

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A Study of Brenipatide in Adults Who Quit Smoking Cigarettes and Want to Avoid Relapse

for Smoking

Drug: Brenipatide

Sites in North Charleston +14 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 75

Code: NCT07223840·Phase 2·Recruiting·Listed Nov 2025

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A Long-term Follow-up Study in Patients Who Received BEAM-101

for Hemoglobinopathy

Sites in Charleston +16 more locations

Sponsor: Beam Therapeutics Inc.

Sex: All·Age: 14 - 37

Code: NCT07373639·Recruiting·Listed Jan 2026

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Evaluation of Efficacy, Safety, and Tolerability of Povetacicept in Participants With Primary Membranous Nephropathy (pMN)

for Primary Membranous Nephropathy

Sites in Greenville, Spartanburg +20 more locations

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 18 - 75

Code: NCT07204275·Phase 2, Phase 3·Recruiting·Listed Oct 2025

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Study of AGN-151607-DP to Assess Adverse Events and Change in Disease Activity in Adult Participants Undergoing Open Abdominal Ventral Hernia Repair

for Ventral Hernia

Sites in Greenville +10 more locations

Sponsor: AbbVie

Sex: All·Age: 18 - 80

Code: NCT07226791·Phase 2·Recruiting·Listed Nov 2025

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FebriDx® Pediatric Validation Study

for Acute Respiratory Infections (ARIs)

Sites in Charleston, Greenville +8 more locations

Sponsor: Lumos Diagnostics

Sex: All·Age: 2 - 11

Code: NCT07211997·Recruiting·Listed Oct 2025

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A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction

for Left Ventricular Systolic Dysfunction

Drug: Finerenone

Sites in North Charleston +21 more locations

Sponsor: Bayer

Sex: All·Age: Up to 18

Code: NCT07192952·Phase 3·Recruiting·Listed Sep 2025

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A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction

for Left Ventricular Systolic Dysfunction

Drug: Finerenone

Sites in North Charleston +21 more locations

Sponsor: Bayer

Sex: All·Age: 6 Months - 17

Code: NCT07188805·Phase 3·Recruiting·Listed Sep 2025

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Brivekimig for the Treatment of Moderate to Severe Hidradenitis Suppurativa

for Hidradenitis Suppurativa

Drug: Brivekimig

Sites in Myrtle Beach +14 more locations

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT07170917·Phase 2·Recruiting·Listed Sep 2025

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A Study to Test Whether Nerandomilast Can Help Slow Down Changes in the Lung in People With a Family History of Pulmonary Fibrosis

for Familial Pulmonary Fibrosis

Drug: Nerandomilast

Sites in Charleston +12 more locations

Sponsor: Boehringer Ingelheim

Sex: All·Age: 40+

Code: NCT07201922·Phase 3·Recruiting·Listed Oct 2025

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A Study of BLB-201 RSV Vaccine in Infants and Children

for Respiratory Syncytial Virus Infections

Sites in Greenville +15 more locations

Sponsor: Blue Lake Biotechnology Inc.

Sex: All·Age: 6 Months - 5·Accepts healthy volunteers

Code: NCT05655182·Phase 1, Phase 2·Recruiting·Listed Dec 2022

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A Study of Zasocitinib in Adults With Nonsegmental Vitiligo

for Nonsegmental Vitiligo

Drug: Zasocitinib

Sites in Charleston +20 more locations

Sponsor: Takeda

Sex: All·Age: 18 - 75

Code: NCT07108283·Phase 2·Recruiting·Listed Aug 2025

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A Study of Dupilumab in Small Children With an Allergic Condition of the Esophagus (Food Pipe): Eosinophilic Esophagitis

for Eosinophilic Esophagitis (EoE)

Drug: Dupilumab

Sites in Charleston +10 more locations

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 6 Months - 6

Code: NCT07112378·Phase 3·Recruiting·Listed Aug 2025

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The ArtixASCEND Study

for Acute Lower Limb Arterial Occlusion

Sites in Spartanburg, Myrtle Beach +15 more locations

Sponsor: Inari Medical

Sex: All·Age: 18+

Code: NCT07135895·Recruiting·Listed Aug 2025

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Study of TDXd, Chemotherapy, Pembrolizumab, and Trastuzumab in First-Line Metastatic HER2-Positive Gastric or Gastroesophageal Junction Cancer

for Gastric Cancer

Sites in Greenville +14 more locations

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT06731478·Phase 3·Recruiting·Listed Dec 2024

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A Study to Learn More About How Risankizumab Works in Young Participants With Ulcerative Colitis

for Ulcerative Colitis

Drug: Risankizumab

Sites in Greenville +10 more locations

Sponsor: AbbVie

Sex: All·Age: 2 - 17

Code: NCT07071519·Phase 3·Recruiting·Listed Jul 2025

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Pivotal Study of the Velocity™ pAVF System

for Chronic Kidney Disease

Sites in Orangeburg +11 more locations

Sponsor: Venova Medical

Sex: All·Age: 18 - 80

Code: NCT07153939·Recruiting·Listed Sep 2025

Apply to this trial

Evaluation of Treatment Satisfaction and KarXT Utilization Registry (RESKU)

for Schizophrenia

Drug: KarXT

Sites in Fort Mill +16 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07101094·Recruiting·Listed Aug 2025

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Abbott Cephea Mitral Valve Disease Registry

for Mitral Regurgitation

Sites in Charleston +22 more locations

Sponsor: Abbott Medical Devices

Sex: All·Age: 18+

Code: NCT07069673·Recruiting·Listed Jul 2025

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A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)

for Obesity

Sites in Charleston +50 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 6 - 17

Code: NCT06672549·Phase 3·Recruiting·Listed Nov 2024

Apply to this trial

Evaluation of a Non-Implanted Electrical Stimulation Device for Overactive Bladder (OAB)

for Overactive Bladder (OAB)

Sites in West Columbia +14 more locations

Sponsor: FemPulse Corporation

Sex: Female·Age: 21+

Code: NCT07195656·Recruiting·Listed Sep 2025

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A Clinical Study of MK-8527 to Prevent Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8527-011)

for Human Immunodeficiency Virus (HIV)

Sites in Columbia +22 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 16+·Accepts healthy volunteers

Code: NCT07044297·Phase 3·Recruiting·Listed Jun 2025

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A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors

for Metastatic Solid Tumor

Sites in Greenville +17 more locations

Sponsor: Coherus Oncology, Inc.

Sex: All·Age: 18+

Code: NCT06657144·Phase 1·Recruiting·Listed Oct 2024

Apply to this trial

Efficacy and Safety of Zanidatamab With Standard-of-care Therapy Against Standard-of-care Therapy for Advanced HER2-positive Biliary Tract Cancer

for Biliary Tract Cancer

Sites in Greenville +12 more locations

Sponsor: Jazz Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06282575·Phase 3·Recruiting·Listed Feb 2024

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Sacral Neuromodulation for Male Overactive Bladder (MOAB)

for Overactive Bladder

Sites in North Charleston +18 more locations

Sponsor: Axonics, Inc.

Sex: Male·Age: 18+

Code: NCT06511141·Recruiting·Listed Jul 2024

Apply to this trial