Paid Clinical Trials in South Carolina

South Carolina has 1,277 paid clinical trials enrolling now across cities including Charleston, Greenville and Columbia. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 16, 2026.

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1,277 clinical trials

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iAmHealthy Clinical Practice Guideline (CPG)

for Pediatric Obesity

4 locations incl. Kansas City

Sponsor: University of Kansas Medical Center

Sex: All·Age: 6 - 11

Code: NCT06888011·Recruiting

Apply to this trial

Phase 2 Study of Inhaled SNG001 in Mechanically Ventilated Patients With Respiratory Viral Infection

for Viral Pneumonia

22 locations incl. Sacramento

Sponsor: Synairgen Research Ltd.

Sex: All·Age: 18+

Code: NCT06999603·Phase 2·Recruiting

Apply to this trial

Accelerated TMS for Seizure-Type Functional Neurologic Disorders

for Functional Neurological Symptom Disorder

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18 - 65

Code: NCT07059325·EARLY_Phase 1·Recruiting

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Arcuate Incisions With Light Adjustable Lens for Astigmatism Correction in Lens Surgery

for Astigmatism

2 locations incl. Venice

Sponsor: Center For Sight

Sex: All·Age: 21+

Code: NCT07140653·Phase 4·Recruiting

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Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a)

for Elevated Lp(a)

Drug: Muvalaplin

121 locations incl. Gilbert

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07157774·Phase 3·Recruiting

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A Study of Pasritamig Versus Placebo in Late Line Metastatic Castration-resistant Prostate Cancer (mCRPC)

for Metastatic Castration-resistant Prostate Neoplasms

Drug: Pasritamig

50 locations incl. La Jolla

Sponsor: Janssen Research & Development, LLC

Sex: Male·Age: 18+

Code: NCT07164443·Phase 3·Recruiting

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Advanced Wireless Augmented Reality-Enhanced Exposure Therapy for Posttraumatic Stress Disorder

for PTSD

1 location in Charleston

Sponsor: Wayne State University

Sex: All·Age: 18+

Code: NCT06740487·Recruiting

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Pistachio Snacking and Metabolic Flexibility

for Overweight (BMI &gt

1 location in Columbia

Sponsor: University of South Carolina

Sex: All·Age: 25 - 45·Accepts healthy volunteers

Code: NCT07340125·Recruiting

Apply to this trial

Mobile Supportive Teams for Reinforcing Increased Daily Exercise Study

for Physical Activity

1 location in Columbia

Sponsor: University of South Carolina

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06662292·Recruiting

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A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

for Advanced Pancreatic Carcinoma

109 locations incl. Birmingham

Sponsor: Sameek Roychowdhury

Sex: All·Age: 18+

Code: NCT06906562·Phase 2·Recruiting

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Development of an mHealth Behavioral Sleep Medicine Intervention for Use During Medication Assisted Treatment for MOUD

for Opioid Use Disorder

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT06157840·Recruiting

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Clinical Alternatives for Reducing Harm Using E-cigarettes

for Smoking

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT07039292·Enrolling By Invitation

BEATRIX: A Study to Learn About a Group B Streptococcus Vaccine in Healthy Pregnant Women and Their Babies

for Healthy

114 locations incl. Birmingham

Sponsor: Pfizer

Sex: All·Age: 1 Day - 49·Accepts healthy volunteers

Code: NCT07160244·Phase 3·Recruiting

Apply to this trial

Telerehabilitation In The Home After Stroke

for Stroke

27 locations incl. Downey

Sponsor: University of California, Los Angeles

Sex: All·Age: 18 - 80

Code: NCT06682429·Recruiting

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OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events

for Cardiovascular Disease

Drug: Olpasiran

204 locations incl. Alexander City

Sponsor: Amgen

Sex: All·Age: 50 - 105

Code: NCT07136012·Phase 3·Recruiting

Apply to this trial

Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer

for Locally Advanced Unresectable Pancreatic Ductal Adenocarcinoma

279 locations incl. Gilbert

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT06958328·Phase 3·Recruiting

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AGENT DCB STANCE: Safety and Effectiveness Study of AGENT Drug-Coated Balloon Compared to Standard of Care Percutaneous Coronary Intervention (PCI) Treatment for de Novo Coronary Lesions

for Coronary Arterial Disease (CAD)

42 locations incl. La Jolla

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT06959524·Recruiting

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Cognitive Decline Following Deep Brain Stimulation: A DBS-fMRI Study

for Deep Brain Stimulation

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06960096·Recruiting

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A Clinical Trial to Evaluate Efficacy and Safety of Xeomin® Injections for Preventing Episodic Migraine

for Episodic Migraine

Drug: Xeomin

46 locations incl. Chandler

Sponsor: Merz Therapeutics GmbH

Sex: All·Age: 18+

Code: NCT07018700·Phase 3·Recruiting

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A Clinical Trial to Evaluate Efficacy and Safety of Xeomin® Injections for Preventing Chronic Migraine

for Chronic Migraine

Drug: Xeomin

46 locations incl. Chandler

Sponsor: Merz Therapeutics GmbH

Sex: All·Age: 18+

Code: NCT07018713·Phase 3·Recruiting

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Real Life Evaluation of the LibAirty Airway Clearance System in Adults With Bronchiectasis (RELACS)

for Bronchiectasis Adult

3 locations incl. Birmingham

Sponsor: Synchrony-Medical, Ltd

Sex: All·Age: 21+

Code: NCT07135284·Recruiting

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Evaluating the Feasibility and Preliminary Effects of BE+

for Lung Cancer (Non-Small Cell)

1 location in Columbia

Sponsor: University of South Carolina

Sex: All·Age: 21+

Code: NCT07214441·Enrolling By Invitation

MiREA-AC for Reducing Problematic Alcohol and Marijuana Use in College Students

for Alcohol Misuse

2 locations incl. Charlotte

Sponsor: mHealth Systems Inc.

Sex: All·Age: 18 - 26·Accepts healthy volunteers

Code: NCT07339150·Recruiting

Apply to this trial

Abbott Cephea Mitral Valve Disease Registry

for Mitral Regurgitation

22 locations incl. Phoenix

Sponsor: Abbott Medical Devices

Sex: All·Age: 18+

Code: NCT07069673·Recruiting

Apply to this trial

Optimizing Care for Cancer Survivors With Depression: Project 3

for Cancer

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT06930729·Recruiting

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Rademikibart Add-on Treatment of an Acute COPD Exacerbation (Seabreeze STAT COPD)

for COPD Acute Exacerbation

22 locations incl. Birmingham

Sponsor: Connect Biopharm LLC

Sex: All·Age: 40 - 80

Code: NCT06940154·Phase 2·Recruiting

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A Long-term Extension Study of ORX750 in Participants With Narcolepsy and Idiopathic Hypersomnia

for Narcolepsy Type 1

Drug: ORX750

19 locations incl. Auburn

Sponsor: Centessa Pharmaceuticals (UK) Limited

Sex: All·Age: 18 - 65

Code: NCT07096674·Phase 2·Recruiting

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Comparison of Two Different Sperm Processing Methods and Their Effects on Sperm DNA Fragmentation and Embryo Development

for DNA Damage

1 location in Greenville

Sponsor: Richard Kordus, PhD, HCLD (ABB)

Sex: All·Age: 18 - 34·Accepts healthy volunteers

Code: NCT06990841·Recruiting

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A Research Study to See How a Weekly Insulin, Insulin Icodec, Helps in Reducing the Blood Sugar Compared to Daily Insulin Glargine, Both in Combination With Insulin Aspart, in Adults With Type 1 Diabetes

for Diabetes Mellitus, Type 1

109 locations incl. Cullman

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07076199·Phase 3·Recruiting

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Saline Enhanced Radiofrequency (SERF) Needle Ablation for Refractory VT

for Refractory Ventricular Tachycardia

5 locations incl. Birmingham

Sponsor: Thermedical, Inc.

Sex: All·Age: 18+

Code: NCT05337241·Recruiting

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Rademikibart Add-on Treatment of an Acute Asthma Exacerbation (Seabreeze STAT Asthma)

for Asthma Acute

22 locations incl. Palo Alto

Sponsor: Connect Biopharm LLC

Sex: All·Age: 12 - 75

Code: NCT06940141·Phase 2·Recruiting

Apply to this trial

Accelerated rTMS vs. Sham for Stroke Apathy

for Apathy

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 40+

Code: NCT07113067·Phase 1, Phase 2·Recruiting

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Direct vs. Conventional SLT in Open-Angle Glaucoma: A RCT

for GLAUCOMA 1, OPEN ANGLE, D (Disorder)

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT06925477·Enrolling By Invitation

A Study to Assess Efficacy and Safety of Baxdrostat in Participants With Primary Aldosteronism

for Primary Hyperaldosteronism

Drug: Baxdrostat

21 locations incl. Los Angeles

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07007793·Phase 3·Recruiting

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A Phase 3 Single-arm Study of UGN-104 for the Treatment of Low-grade Upper Tract Urothelial Cancer

for Upper Urinary Tract Urothelial Carcinoma

23 locations incl. Homewood

Sponsor: UroGen Pharma Ltd.

Sex: All·Age: 18+

Code: NCT06774131·Phase 3·Recruiting

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A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation

for Prostate Cancer

Drug: Saruparib

42 locations incl. Phoenix

Sponsor: AstraZeneca

Sex: Male·Age: 18+

Code: NCT06952803·Phase 3·Recruiting

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Physical Capacity Building for Chronic Stroke

for Stroke

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18 - 80

Code: NCT07039305·Recruiting

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Study to Evaluate the Efficacy and Safety of Deuruxolitinib in Adolescents With Severe Alopecia Areata

for Alopecia Areata

54 locations incl. Birmingham

Sponsor: Sun Pharmaceutical Industries, Inc.

Sex: All·Age: 12 - 17

Code: NCT07133308·Phase 3·Recruiting

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A Study of Dotinurad Versus Allopurinol in Tophaceous Gout

for Tophaceous Gout

Drug: Dotinurad

86 locations incl. Birmingham

Sponsor: Crystalys Therapeutics

Sex: All·Age: 18 - 75

Code: NCT07089888·Phase 3·Recruiting

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A Study of Dotinurad Versus Allopurinol in Participants With Gout

for Gout

Drug: Dotinurad

80 locations incl. Birmingham

Sponsor: Crystalys Therapeutics

Sex: All·Age: 18 - 75

Code: NCT07089875·Phase 3·Recruiting

Apply to this trial