Paid Clinical Trials in South Carolina

South Carolina has 1,217 paid clinical trials enrolling now across cities including Charleston, Greenville and Columbia. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 14, 2026.

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1,101 clinical trials

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Pompe Pregnancy Sub-Registry

for Glycogen Storage Disease Type II (GSD-II)

Sites in Greenville +13 more locations

Sponsor: Genzyme, a Sanofi Company

Sex: Female·Age: All ages

Code: NCT00567073·Recruiting·Listed Dec 2007

Apply to this trial

Helix Research Network

for Genetic Predisposition to Disease

Sites in Charleston +13 more locations

Sponsor: Helix, Inc

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06057181·Recruiting·Listed Sep 2023

Apply to this trial

Clinical Safety and Efficacy of the VDyne Transcatheter Tricuspid Valve Replacement System for the Treatment of Tricuspid Regurgitation ( VISTA-US)

for Tricuspid Regurgitation

Sites in Charleston +9 more locations

Sponsor: VDyne, Inc.

Sex: All·Age: 18+

Code: NCT05848284·Recruiting·Listed May 2023

Apply to this trial

The MIRROR Registry: Minimally Invasive IntRaceRebral HemORrhage Evacuation

for Supratentorial Hemorrhage

Sites in Greenville +17 more locations

Sponsor: Integra LifeSciences Corporation

Sex: All·Age: 18+

Code: NCT04494295·Recruiting·Listed Jul 2020

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52 Week Study + 24-Month Long-Term Extension of Safety, PK, & Efficacy of XYOSTED® for Testosterone Replacement in Male Adolescents With Hypogonadism

for Hypogonadism, Male

Sites in Columbia +19 more locations

Sponsor: Halozyme Therapeutics

Sex: Male·Age: 12 - 17

Code: NCT06689085·Phase 3·Recruiting·Listed Nov 2024

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A Non-interventional, Post-authorisation Safety Study of Patients Treated With Efgartigimod Alfa

for Myasthenia Gravis

Sites in Charleston +16 more locations

Sponsor: argenx

Sex: All·Age: 18+

Code: NCT06298565·Recruiting·Listed Mar 2024

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A Dose Escalation Study of AV-380 in Cancer Patients With Cachexia

for Cachexia

Sites in Charleston +11 more locations

Sponsor: AVEO Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT05865535·Phase 1·Recruiting·Listed May 2023

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Long-Term Stability of the Glide Control Strategy

for Upper Limb Amputation Above Elbow

Sites in Greenville, Anderson +8 more locations

Sponsor: Infinite Biomedical Technologies

Sex: All·Age: 18+

Code: NCT07222085·Recruiting·Listed Oct 2025

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A Study of TAK-861 for the Treatment of Selected Central Hypersomnia Conditions

for Narcolepsy Type 1

Sites in Charleston, Columbia +17 more locations

Sponsor: Takeda

Sex: All·Age: 16 - 70

Code: NCT05816382·Phase 2, Phase 3·Recruiting·Listed Apr 2023

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A Study to Evaluate the Safety and Effectiveness of the InnAVasc Arteriovenous Graft for Hemodialysis Access in Patients With End-Stage Renal Disease

for End Stage Renal Disease (ESRD)

Sites in Greenville, Orangeburg +18 more locations

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18 - 90

Code: NCT04671771·Recruiting·Listed Dec 2020

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Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

for Non Small Cell Lung Cancer

Sites in Greenville +23 more locations

Sponsor: SystImmune Inc.

Sex: All·Age: 18+

Code: NCT05983432·Phase 1·Recruiting·Listed Aug 2023

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A Study of Nipocalimab Administered to Adults With Generalized Myasthenia Gravis

for Myasthenia Gravis

Drug: Nipocalimab

Sites in Charleston +10 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT04951622·Phase 3·Recruiting·Listed Jul 2021

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Melodi Matrix™ in Breast Reconstruction

for Breast Reconstruction

Sites in Charleston +9 more locations

Sponsor: Melodi Health, Inc.

Sex: Female·Age: 22+

Code: NCT06027996·Recruiting·Listed Sep 2023

Apply to this trial

Blue Light Cystoscopy With Cysview® Registry

for Bladder Cancer

Sites in West Columbia +20 more locations

Sponsor: Photocure

Sex: All·Age: 18+

Code: NCT02660645·Recruiting·Listed Jan 2016

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(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis

for Advanced Systemic Mastocytosis (AdvSM)

Sites in Charleston +8 more locations

Sponsor: Cogent Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT04996875·Phase 2·Recruiting·Listed Aug 2021

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Maturation of Arteriovenous Fistula With Automated Sonography Assessments Trial

for Diabetes

Sites in Greenville, Orangeburg +18 more locations

Sponsor: Sonavex, Inc.

Sex: All·Age: 18 - 84

Code: NCT06190717·Recruiting·Listed Jan 2024

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VALOR: Vaginal Atrophy & Long-term Observation of Recovery

for Atrophic Vaginitis

Sites in Charleston, West Columbia +11 more locations

Sponsor: Stratpharma AG

Sex: Female·Age: 18+

Code: NCT05953090·Recruiting·Listed Jul 2023

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Phase 2 Study of Inhaled SNG001 in Mechanically Ventilated Patients With Respiratory Viral Infection

for Viral Pneumonia

Sites in Anderson +21 more locations

Sponsor: Synairgen Research Ltd.

Sex: All·Age: 18+

Code: NCT06999603·Phase 2·Recruiting·Listed May 2025

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Exactech Shoulder Post Market Clinical Follow-up Study

for Osteo Arthritis Shoulders

Sites in Charleston, Greenville +22 more locations

Sponsor: Exactech

Sex: All·Age: 21+

Code: NCT05603728·Recruiting·Listed Nov 2022

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A Biospecimen Collection Study to Identify the Targets of Disease-Reactive T Cells in Patients With Autoimmune Disease

for Autoimmune Diseases

Sites in Summerville +10 more locations

Sponsor: TScan Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06587828·Recruiting·Listed Sep 2024

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Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors

for Head and Neck Squamous Cell Carcinoma

Sites in Charleston +14 more locations

Sponsor: Bicara Therapeutics

Sex: All·Age: 18+

Code: NCT04429542·Phase 1·Recruiting·Listed Jun 2020

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Intravesical Photodynamic Therapy ("PDT") in BCG-Unresponsive/Intolerant Non-Muscle Invasive Bladder Cancer ("NMIBC") Patients

for Non-Muscle Invasive Bladder Cancer ("NMIBC") Unresponsive/Intolerant to BCG

Sites in Myrtle Beach +6 more locations

Sponsor: Theralase® Technologies Inc.

Sex: All·Age: 18+

Code: NCT03945162·Phase 2·Recruiting·Listed May 2019

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A Study of STM-416 Administered to Patients Undergoing TURBT for Recurrent Bladder Cancer

for Non-muscle-invasive Bladder Cancer

Sites in Myrtle Beach, North Charleston +17 more locations

Sponsor: SURGE Therapeutics

Sex: All·Age: 18+

Code: NCT05710848·Phase 1, Phase 2·Recruiting·Listed Feb 2023

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A Real World Study of eCoin for Urgency Urinary Incontinence: Post Approval Evaluation (RECIPE)

for Overactive Bladder

Sites in West Columbia +18 more locations

Sponsor: Valencia Technologies Corporation

Sex: All·Age: 18+

Code: NCT05685433·Recruiting·Listed Jan 2023

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Serranator POINT FORCE Registry

for Peripheral Artery Disease (PAD)

Sites in Greenville +17 more locations

Sponsor: Cagent Vascular LLC

Sex: All·Age: 18+

Code: NCT06687590·Recruiting·Listed Nov 2024

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Cardiac RADIoablation Versus Repeat Catheter Ablation: a Pivotal Randomized Clinical Trial Evaluating Safety and Efficacy for Patients With High-risk Refractory Ventricular Tachycardia (RADIATE-VT)

for Tachycardia, Ventricular

Sites in Charleston +10 more locations

Sponsor: Varian, a Siemens Healthineers Company

Sex: All·Age: 18+

Code: NCT05765175·Recruiting·Listed Mar 2023

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A Long-term Extension Study of ORX750 in Participants With Narcolepsy and Idiopathic Hypersomnia

for Narcolepsy Type 1

Drug: ORX750

Sites in North Charleston +18 more locations

Sponsor: Centessa Pharmaceuticals (UK) Limited

Sex: All·Age: 18 - 65

Code: NCT07096674·Phase 2·Recruiting·Listed Jul 2025

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Pivotal Study for the Cardiac Performance System (CPS)

for Cardiovascular Diseases

Sites in Charleston +9 more locations

Sponsor: Sensydia Corporation

Sex: All·Age: 18+

Code: NCT06870591·Recruiting·Listed Mar 2025

Apply to this trial

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

for Brain Cancer

Sites in Charleston, Florence +14 more locations

Sponsor: Adela, Inc

Sex: All·Age: 40+·Accepts healthy volunteers

Code: NCT05366881·Recruiting·Listed May 2022

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Safety, PK, and Preliminary Efficacy of MBRC-101 in Advanced Refractory Solid Tumors

for Cancer

Sites in Charleston, Greenville +13 more locations

Sponsor: MBrace Therapeutics

Sex: All·Age: 18+

Code: NCT06014658·Phase 1, Phase 2·Recruiting·Listed Aug 2023

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Treatment of Pulmonary Arterial Hypertension Using the Aria CV Pulmonary Hypertension System

for Pulmonary Arterial Hypertension

Sites in Charleston +8 more locations

Sponsor: Aria CV, Inc

Sex: All·Age: 18+

Code: NCT04555161·Recruiting·Listed Sep 2020

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Study Evaluating INS018_055 Administered Orally to Subjects With Idiopathic Pulmonary Fibrosis

for Idiopathic Pulmonary Fibrosis (IPF)

Sites in Columbia +11 more locations

Sponsor: InSilico Medicine Hong Kong Limited

Sex: All·Age: 40+

Code: NCT05975983·Phase 2·Recruiting·Listed Aug 2023

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uTRACT Jelmyto Registry: A Registry of Patients With Upper Tract Urothelial Cancer (UTUC) Treated With Jelmyto

for Urothelial Carcinoma

Sites in Charleston +21 more locations

Sponsor: UroGen Pharma Ltd.

Sex: All·Age: 18+

Code: NCT05874921·Recruiting·Listed May 2023

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A Study of AK117 in Combination With Azacitidine in Patients With Myelodysplastic Syndromes

for Higher-risk Myelodysplastic Syndromes

Sites in Charleston +13 more locations

Sponsor: Akeso

Sex: All·Age: 18+

Code: NCT06196203·Phase 2·Recruiting·Listed Jan 2024

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An Early Feasibility Study of the HighLife 28mm Trans-Septal Transcatheter Mitral Valve Replacement System

for Mitral Regurgitation

Sites in Charleston +7 more locations

Sponsor: HighLife SAS

Sex: All·Age: 18+

Code: NCT04029337·Recruiting·Listed Jul 2019

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Clinical Utility of Management of Patients With Pulmonary Nodules Using the Percepta Nasal Swab Classifier

for Pulmonary Nodule, Solitary

Sites in Charleston +21 more locations

Sponsor: Veracyte, Inc.

Sex: All·Age: 29 - 85

Code: NCT06426628·Recruiting·Listed May 2024

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Nafamostat Efficacy in Phase 3 Registrational CRRT Study

for Acute Kidney Injury

Sites in Charleston +9 more locations

Sponsor: Talphera, Inc

Sex: All·Age: 18 - 80

Code: NCT06150742·Recruiting·Listed Nov 2023

Apply to this trial

Idiopathic Pulmonary Fibrosis (IPF)-Related Chronic Cough Reduction With Nalbuphine Extended-Release (NAL ER) Tablets

for Idiopathic Pulmonary Fibrosis

Sites in Anderson +14 more locations

Sponsor: Trevi Therapeutics

Sex: All·Age: 40+

Code: NCT07671911·Phase 3·Recruiting·Listed Jun 2026

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A Phase 1/2 Study of KK2430 in Participants With Hematologic Neoplasms

for Hematologic Neoplasms

1 location in Greenville

Sponsor: Kyowa Kirin Co., Ltd.

Sex: All·Age: 18+

Code: NCT07629726·Phase 1, Phase 2·Recruiting·Listed Jun 2026

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Privosegtor Investigation in Optic Neuropathies Efficacy Evaluation Research

for Optic Neuritis

Sites in Charleston +3 more locations

Sponsor: Oculis

Sex: All·Age: 18 - 50

Code: NCT07623668·Phase 3·Recruiting·Listed Jun 2026

Apply to this trial