Paid Clinical Trials in South Carolina

South Carolina has 1,226 paid clinical trials enrolling now across cities including Charleston, Greenville and Columbia. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 31, 2026.

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1,109 clinical trials

A Study of STM-416 Administered to Patients Undergoing TURBT for Recurrent Bladder Cancer

for Non-muscle-invasive Bladder Cancer

Sites in Myrtle Beach, North Charleston +17 more locations

Sponsor: SURGE Therapeutics

Sex: All·Age: 18+

Code: NCT05710848·Phase 1, Phase 2·Recruiting·Listed Feb 2023

Apply to this trial

Exactech Shoulder Post Market Clinical Follow-up Study

for Osteo Arthritis Shoulders

Sites in Charleston, Greenville +22 more locations

Sponsor: Exactech

Sex: All·Age: 21+

Code: NCT05603728·Recruiting·Listed Nov 2022

Apply to this trial

A Biospecimen Collection Study to Identify the Targets of Disease-Reactive T Cells in Patients With Autoimmune Disease

for Autoimmune Diseases

Sites in Summerville +10 more locations

Sponsor: TScan Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06587828·Recruiting·Listed Sep 2024

Apply to this trial

A Real World Study of eCoin for Urgency Urinary Incontinence: Post Approval Evaluation (RECIPE)

for Overactive Bladder

Sites in West Columbia +18 more locations

Sponsor: Valencia Technologies Corporation

Sex: All·Age: 18+

Code: NCT05685433·Recruiting·Listed Jan 2023

Apply to this trial

Serranator POINT FORCE Registry

for Peripheral Artery Disease (PAD)

Sites in Greenville +17 more locations

Sponsor: Cagent Vascular LLC

Sex: All·Age: 18+

Code: NCT06687590·Recruiting·Listed Nov 2024

Apply to this trial

Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors

for Head and Neck Squamous Cell Carcinoma

Sites in Charleston +14 more locations

Sponsor: Bicara Therapeutics

Sex: All·Age: 18+

Code: NCT04429542·Phase 1·Recruiting·Listed Jun 2020

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Intravesical Photodynamic Therapy ("PDT") in BCG-Unresponsive/Intolerant Non-Muscle Invasive Bladder Cancer ("NMIBC") Patients

for Non-Muscle Invasive Bladder Cancer ("NMIBC") Unresponsive/Intolerant to BCG

Sites in Myrtle Beach +6 more locations

Sponsor: Theralase® Technologies Inc.

Sex: All·Age: 18+

Code: NCT03945162·Phase 2·Recruiting·Listed May 2019

Apply to this trial

Total Shoulder Arthroplasty Multi-Center Registry

for Shoulder Arthroplasty

Sites in Greenville +14 more locations

Sponsor: Arthrex, Inc.

Sex: All·Age: 18 - 100

Code: NCT03511586·Recruiting·Listed Apr 2018

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Study of ORIC-114 in Patients With Advanced Solid Tumors Harboring an EGFR or HER2 Alteration

for Solid Tumors

Sites in Spartanburg +16 more locations

Sponsor: ORIC Pharmaceuticals

Sex: All·Age: 18+

Code: NCT05315700·Phase 1, Phase 2·Recruiting·Listed Apr 2022

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(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis

for Advanced Systemic Mastocytosis (AdvSM)

Sites in Charleston +8 more locations

Sponsor: Cogent Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT04996875·Phase 2·Recruiting·Listed Aug 2021

Apply to this trial

A Long-term Extension Study of ORX750 in Participants With Narcolepsy and Idiopathic Hypersomnia

for Narcolepsy Type 1

Drug: ORX750

Sites in North Charleston +18 more locations

Sponsor: Centessa Pharmaceuticals (UK) Limited

Sex: All·Age: 18 - 65

Code: NCT07096674·Phase 2·Recruiting·Listed Jul 2025

Apply to this trial

Cardiac RADIoablation Versus Repeat Catheter Ablation: a Pivotal Randomized Clinical Trial Evaluating Safety and Efficacy for Patients With High-risk Refractory Ventricular Tachycardia (RADIATE-VT)

for Tachycardia, Ventricular

Sites in Charleston +10 more locations

Sponsor: Varian, a Siemens Healthineers Company

Sex: All·Age: 18+

Code: NCT05765175·Recruiting·Listed Mar 2023

Apply to this trial

Pivotal Study for the Cardiac Performance System (CPS)

for Cardiovascular Diseases

Sites in Charleston +9 more locations

Sponsor: Sensydia Corporation

Sex: All·Age: 18+

Code: NCT06870591·Recruiting·Listed Mar 2025

Apply to this trial

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

for Brain Cancer

Sites in Charleston, Florence +14 more locations

Sponsor: Adela, Inc

Sex: All·Age: 40+·Accepts healthy volunteers

Code: NCT05366881·Recruiting·Listed May 2022

Apply to this trial

Study to Evaluate ARINA-1 in the Prevention of Bronchiolitis Obliterans Progression in Participants With Bilateral Lung Transplant

for Pre-Bronchiolitis Obliterans Syndrome

Sites in Charleston +17 more locations

Sponsor: Renovion, Inc.

Sex: All·Age: 18 - 75

Code: NCT05654922·Phase 3·Recruiting·Listed Dec 2022

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Safety, PK, and Preliminary Efficacy of MBRC-101 in Advanced Refractory Solid Tumors

for Cancer

Sites in Charleston, Greenville +13 more locations

Sponsor: MBrace Therapeutics

Sex: All·Age: 18+

Code: NCT06014658·Phase 1, Phase 2·Recruiting·Listed Aug 2023

Apply to this trial

Treatment of Pulmonary Arterial Hypertension Using the Aria CV Pulmonary Hypertension System

for Pulmonary Arterial Hypertension

Sites in Charleston +8 more locations

Sponsor: Aria CV, Inc

Sex: All·Age: 18+

Code: NCT04555161·Recruiting·Listed Sep 2020

Apply to this trial

Study Evaluating INS018_055 Administered Orally to Subjects With Idiopathic Pulmonary Fibrosis

for Idiopathic Pulmonary Fibrosis (IPF)

Sites in Columbia +11 more locations

Sponsor: InSilico Medicine Hong Kong Limited

Sex: All·Age: 40+

Code: NCT05975983·Phase 2·Recruiting·Listed Aug 2023

Apply to this trial

uTRACT Jelmyto Registry: A Registry of Patients With Upper Tract Urothelial Cancer (UTUC) Treated With Jelmyto

for Urothelial Carcinoma

Sites in Charleston +21 more locations

Sponsor: UroGen Pharma Ltd.

Sex: All·Age: 18+

Code: NCT05874921·Recruiting·Listed May 2023

Apply to this trial

A Study of AK117 in Combination With Azacitidine in Patients With Myelodysplastic Syndromes

for Higher-risk Myelodysplastic Syndromes

Sites in Charleston +13 more locations

Sponsor: Akeso

Sex: All·Age: 18+

Code: NCT06196203·Phase 2·Recruiting·Listed Jan 2024

Apply to this trial

A Retrospective Assessment of OviTex PRS (OviTex)

for Reconstructive Surgical Procedures

Sites in Columbia +6 more locations

Sponsor: Tela Bio Inc

Sex: Female·Age: 18 - 75

Code: NCT05736848·Recruiting·Listed Feb 2023

Apply to this trial

An Early Feasibility Study of the HighLife 28mm Trans-Septal Transcatheter Mitral Valve Replacement System

for Mitral Regurgitation

Sites in Charleston +7 more locations

Sponsor: HighLife SAS

Sex: All·Age: 18+

Code: NCT04029337·Recruiting·Listed Jul 2019

Apply to this trial

Nafamostat Efficacy in Phase 3 Registrational CRRT Study

for Acute Kidney Injury

Sites in Charleston +9 more locations

Sponsor: Talphera, Inc

Sex: All·Age: 18 - 80

Code: NCT06150742·Recruiting·Listed Nov 2023

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Clinical Utility of Management of Patients With Pulmonary Nodules Using the Percepta Nasal Swab Classifier

for Pulmonary Nodule, Solitary

Sites in Charleston +21 more locations

Sponsor: Veracyte, Inc.

Sex: All·Age: 29 - 85

Code: NCT06426628·Recruiting·Listed May 2024

Apply to this trial

A Study to Evaluate Efficacy and Safety of MELT-300 for Procedural Sedation in Subjects Undergoing Cataract Extraction With Lens Replacement (CELR)

for Cataract

Sites in Conway +11 more locations

Sponsor: Melt Pharmaceuticals

Sex: All·Age: 18 - 65

Code: NCT06383273·Phase 3·Recruiting·Listed Apr 2024

Apply to this trial

Post Approval Study of Liposorber LA-15 System for the Treatment of Focal Segmental Glomerulosclerosis in Children

for Focal Segmental Glomerulosclerosis

Sites in Charleston +9 more locations

Sponsor: Kaneka Medical America LLC

Sex: All·Age: Up to 21

Code: NCT02235857·Recruiting·Listed Sep 2014

Apply to this trial

Specimen Collection from Pregnant Women At Increased Risk for Fetal Aneuploidy

for Down Syndrome

Sites in Charleston +11 more locations

Sponsor: Sequenom, Inc.

Sex: Female·Age: 18+

Code: NCT01429389·Recruiting·Listed Sep 2011

Apply to this trial

Post Approval Study for Treatment of Drug-resistant Adult and Pediatric Primary FSGS Using the LIPOSORBER® LA-15 System

for Focal Segmental Glomerulosclerosis

Sites in Charleston +9 more locations

Sponsor: Kaneka Medical America LLC

Sex: All·Age: Up to 75

Code: NCT04065438·Recruiting·Listed Aug 2019

Apply to this trial

A Phase 2A Clinical Trial to Assess the Safety and Tolerability of ERX1000 in Men and Women for the Treatment of Obesity.

for Obesity & Overweight

Sites in North Charleston +2 more locations

Sponsor: ERX Pharmaceuticals

Sex: All·Age: 18 - 60

Code: NCT07570758·Phase 2·Recruiting·Listed May 2026

Apply to this trial

A Study to Investigate the Effects of Cleminorexton Compared With Placebo in the Treatment of Participants With Central Disorders of Hypersomnolence

for Narcolepsy Type 1

Sites in Columbia +9 more locations

Sponsor: Centessa Pharmaceuticals (UK) Limited

Sex: All·Age: 18 - 70

Code: NCT07598708·Phase 2, Phase 3·Recruiting·Listed May 2026

Apply to this trial

A Phase 1/2 Study of KK2430 in Participants With Hematologic Neoplasms

for Hematologic Neoplasms

1 location in Greenville

Sponsor: Kyowa Kirin Co., Ltd.

Sex: All·Age: 18+

Code: NCT07629726·Phase 1, Phase 2·Recruiting·Listed Jun 5, 2026

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Ixoberogene Soroparvovec (Ixo-vec) Contralateral Dosing Study in Participants With Neovascular Age-related Macular Degeneration

for Neovascular Age-Related Macular Degeneration (nAMD) Wet AMD

Drug: Ixo-vec

Sites in West Columbia +3 more locations

Sponsor: Adverum Biotechnologies, Inc.

Sex: All·Age: 50+

Code: NCT07630649·Phase 2·Recruiting·Listed Jun 5, 2026

Apply to this trial

A Study Evaluating Disease Characteristics and Outcomes in Participants With Asthma in Routine Clinical Practice

for Asthma

Sites in Rock Hill +50 more locations

Sponsor: Sanofi

Sex: All·Age: 6+

Code: NCT07556159·Recruiting·Listed Apr 2026

Apply to this trial

Study to Evaluate Long-Term Safety of Intravitreal OTX-TKI (Axitinib Implant) in Participants With Neovascular Age-Related Macular Degeneration Who Successfully Completed 2-Year OTX-TKI-2023-AMD-301 or OTX-TKI-2023-AMD-303 Study

for Neovascular Age-Related Macular Degeneration (nAMD)

Sites in West Columbia +7 more locations

Sponsor: Ocular Therapeutix, Inc.

Sex: All·Age: 50+

Code: NCT07516132·Phase 3·Recruiting·Listed Apr 2026

Apply to this trial

Prostate Cancer Risk Identification in a Multi-Ethnic Cohort: a Prospective US-based Multi-center Validation Study of Proclarix

for Prostate Cancer Detection

Sites in Myrtle Beach +5 more locations

Sponsor: Sequenom, Inc.

Sex: Male·Age: 40 - 75

Code: NCT07543757·Recruiting·Listed Apr 2026

Apply to this trial

A Study to Find Out if Enfortumab Vedotin Given With Pembrolizumab Helps People With Muscle-invasive Bladder Cancer Keep Their Bladder

for Muscle-invasive Bladder Cancer

Sites in Myrtle Beach +8 more locations

Sponsor: Astellas Pharma Global Development, Inc.

Sex: All·Age: 18+

Code: NCT07475806·Phase 2·Recruiting·Listed Mar 2026

Apply to this trial

Clareon TruPlus Study

for Aphakia

Sites in Mt. Pleasant +4 more locations

Sponsor: Alcon Research

Sex: All·Age: 22+

Code: NCT07502456·Recruiting·Listed Mar 2026

Apply to this trial

Post Approval Effectiveness and Durability Evaluation of the Altaviva™ Tibial Device

for Urge Urinary Incontinence

Sites in West Columbia +9 more locations

Sponsor: MedtronicNeuro

Sex: All·Age: 18+

Code: NCT07456865·Recruiting·Listed Mar 2026

Apply to this trial

Efficacy and Safety of Intravesical TARA-002 Compared With Investigator's Choice of Intravesical Chemotherapy in Participants With BCG-naïve High-grade Non-muscle Invasive Bladder Cancer

for Bladder (Urothelial, Transitional Cell) Cancer

Sites in Myrtle Beach +4 more locations

Sponsor: Protara Therapeutics

Sex: All·Age: 18+

Code: NCT07480356·Phase 3·Recruiting·Listed Mar 2026

Apply to this trial

A Phase 1 Study of the Safety and Tolerability of CTX-10726

for Gastroesophageal Cancer (GC)

Drug: CTX-10726

Sites in Greenville +5 more locations

Sponsor: Compass Therapeutics

Sex: All·Age: 18+

Code: NCT07419841·Phase 1·Recruiting·Listed Feb 2026

Apply to this trial