Paid Clinical Trials in South Carolina

South Carolina has 1,226 paid clinical trials enrolling now across cities including Charleston, Greenville and Columbia. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 31, 2026.

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1,109 clinical trials

A Study of GEN1106 in Participants With Solid Tumors

for Solid Tumors

Drug: GEN1106

Sites in Myrtle Beach +3 more locations

Sponsor: Genmab

Sex: All·Age: 18+

Code: NCT07416123·Phase 1·Recruiting·Listed Feb 2026

Apply to this trial

Ambulatory Long Length URodynamics Evaluation

for Urology

Sites in West Columbia +6 more locations

Sponsor: Bright Uro

Sex: All·Age: 22+

Code: NCT07425015·Recruiting·Listed Feb 2026

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Paclitaxel-Coated Balloon Treatment of Chronic Rhinosinusitis

for Chronic Rhinosinusitis (CRS) With and Without Nasal Polyps

Sites in Charleston +9 more locations

Sponsor: Airiver Medical, Inc.

Sex: All·Age: 18+

Code: NCT07290140·Recruiting·Listed Dec 2025

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A Study to Test Inavolisib Treatment in Participants With Metastatic Castration-Resistant Prostate Cancer

for Metastatic Castration-Resistant Prostate Cancer

Sites in Myrtle Beach +5 more locations

Sponsor: Hoffmann-La Roche

Sex: Male·Age: 18+

Code: NCT07287150·Phase 2·Recruiting·Listed Dec 2025

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A Study of TSRA-196 in Adults With PiZZ Alpha-1 Antitrypsin Deficiency (AATD)

for Alpha-1 Antitrypsin Deficiency (AATD)

Sites in Charleston +2 more locations

Sponsor: Tessera Therapeutics, Inc.

Sex: All·Age: 18 - 70

Code: NCT07227207·Phase 1, Phase 2·Recruiting·Listed Nov 2025

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A Biomarker Study in Men With Localized Prostate Cancer Treated With Aglatimagene Besadenovec

for Prostate Cancer Patients Treated by Radiotherapy

Sites in Myrtle Beach +6 more locations

Sponsor: Candel Therapeutics, Inc.

Sex: Male·Age: 18+

Code: NCT07332000·Phase 2·Recruiting·Listed Jan 2026

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Evaluating ER-100 for Safety in People With Glaucoma or Non-Arteritic Anterior Ischemic Optic Neuropathy (Optic Nerve Conditions)

for Open Angle Glaucoma (OAG)

Sites in Charleston +3 more locations

Sponsor: Life Biosciences Inc.

Sex: All·Age: 40 - 85

Code: NCT07290244·Phase 1·Recruiting·Listed Dec 2025

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A Study of Valemetostat (DS-3201b) in Combination With Darolutamide in Metastatic Castration Resistant Prostate Cancer (mCRPC)

for Metastatic Castration-resistant Prostate Cancer

Sites in Myrtle Beach +8 more locations

Sponsor: Daiichi Sankyo

Sex: Male·Age: 18+

Code: NCT07244341·Phase 1·Recruiting·Listed Nov 2025

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REVEAL Study - Diagnostic Testing for PTSD Using the Senseye Diagnostic Tool

for PTSD - Post Traumatic Stress Disorder

Sites in Charleston +4 more locations

Sponsor: Senseye, Inc.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07280065·Phase 3·Recruiting·Listed Dec 2025

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A Clinical Study of MK-3120 in People With Bladder Cancer (MK-3120-003)

for Bladder Cancer

Sites in Myrtle Beach +1 more location

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT07222488·Phase 1, Phase 2·Recruiting·Listed Oct 2025

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Managing Pain Using Optimized Sequences by Adjusting Parameters With Independent Current Control

for Chronic Pain

Sites in Greenville +6 more locations

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT07190807·Recruiting·Listed Sep 2025

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Study Evaluating the Safety, Tolerability, and Efficacy of Xaluritamig in Combination With Androgen Receptor Pathway Inhibitors in Participants With Metastatic Hormone-sensitive Prostate Cancer

for Metastatic Hormone-sensitive Prostate Cancer (mHSPC)

Sites in Myrtle Beach +7 more locations

Sponsor: Amgen

Sex: Male·Age: 18+

Code: NCT07140900·Phase 1·Recruiting·Listed Aug 2025

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A Study to Evaluate the Efficacy and Safey of PTP-001 (MOTYS™) in Knee Osteoarthritis Patients

for Knee Osteoarthritis

Sites in North Charleston +7 more locations

Sponsor: Doron Therapeutics Inc.

Sex: All·Age: 40 - 80

Code: NCT07219771·Phase 3·Recruiting·Listed Oct 2025

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Early Feasibility Study (EFS) Evaluating Percutaneous Repair of the Atrial Septum With a Novel PFO Occluder: The PROTEA-PFO Study

for PFO

Sites in Greenville +4 more locations

Sponsor: Recross Cardio, Inc.

Sex: All·Age: 18 - 65

Code: NCT07172464·Recruiting·Listed Sep 2025

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TulmiSTAR-02: A Phase I/II Open-label Study of Tulmimetostat in Combination With Darolutamide vs. Darolutamide, and Tulmimetostat With Abiraterone in Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)

for Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)

Drug: Tulmimetostat

Sites in Charleston, Myrtle Beach +6 more locations

Sponsor: Novartis Pharmaceuticals

Sex: Male·Age: 18+

Code: NCT07190300·Phase 1, Phase 2·Recruiting·Listed Sep 2025

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A Prospective, Post-Market, Clinical Follow-up Study of the Incompass™ Total Ankle System

for Post Traumatic Arthritis

Sites in Charleston +4 more locations

Sponsor: Stryker Trauma and Extremities

Sex: All·Age: 21+

Code: NCT07118501·Recruiting·Listed Aug 2025

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SAINT in Postpartum Depression (PPD)

for Postpartum Depression (PPD)

Sites in Charleston +3 more locations

Sponsor: Magnus Medical

Sex: Female·Age: 18 - 45

Code: NCT07210255·Recruiting·Listed Oct 2025

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A Phase 1 AAV Gene Therapy Trial Evaluating Safety and Preliminary Efficacy of RP-A701 in Subjects With BAG3 Dilated Cardiomyopathy

for Dilated Cardiomyopathy (DCM)

Sites in Charleston +2 more locations

Sponsor: Rocket Pharmaceuticals Inc.

Sex: All·Age: 18 - 65

Code: NCT07137338·Phase 1·Recruiting·Listed Aug 2025

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EVERO Drug-coated Balloon (DCB) Randomized Trial

for Peripheral Vascular Disease

Sites in Greenville +6 more locations

Sponsor: Cook Research Incorporated

Sex: All·Age: 18+

Code: NCT07144150·Recruiting·Listed Aug 2025

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A Long-term Study of the Medicine Called Abrocitinib in Children Aged 2 Years and Older With Moderate to Severe Eczema

for Atopic Dermatitis

Sites in Charleston, Greenville +7 more locations

Sponsor: Pfizer

Sex: All·Age: 2 - 11

Code: NCT06807281·Phase 3·Recruiting·Listed Feb 2025

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Study of 30-Minute Stimulation With the Neuspera Sacral Neuromodulation (SNM) System

for Urinary Urge Incontinence

1 location in West Columbia

Sponsor: Neuspera Medical, Inc.

Sex: All·Age: 22+

Code: NCT07247136·Recruiting·Listed Nov 2025

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Trial Investigating Visugromab in Combination With Immunochemotherapy in 1L Treatment of Participants With Metastatic NSCLC

for Metastatic Non-Squamous Non-Small Cell Lung Cancer

Sites in Charleston +6 more locations

Sponsor: CatalYm GmbH

Sex: All·Age: 18+

Code: NCT07098988·Phase 2·Recruiting·Listed Aug 2025

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GORE® ENFORM Biomaterial Product Study

for Hernia, Ventral

Sites in Greenville +6 more locations

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18+

Code: NCT04718168·Recruiting·Listed Jan 2021

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A Study in Adults to Learn About Inherited Alpha-1 Antitrypsin Deficiency (AATD) and AATD Related Liver Problems

for Alpha1-Antitrypsin Deficiency

Sites in Charleston +2 more locations

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT06512454·Recruiting·Listed Jul 2024

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The TRICURE EFS Study

for Tricuspid Valve Regurgitation

Sites in Charleston +7 more locations

Sponsor: TRiCares

Sex: All·Age: 18+

Code: NCT06506942·Recruiting·Listed Jul 2024

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Integrity Implant System Post Market Clinical Follow-Up Study

for Rotator Cuff Tears of the Shoulder

Sites in Greenville +8 more locations

Sponsor: Anika Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06741527·Recruiting·Listed Dec 2024

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SPI-1005 in Adults Receiving Cochlear Implant

for Hearing Loss

Sites in Charleston +5 more locations

Sponsor: Sound Pharmaceuticals, Incorporated

Sex: All·Age: 18+

Code: NCT06340633·Phase 2·Recruiting·Listed Apr 2024

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NV PSR INSPIRE-A Pipeline™ Vantage Post Approval Study

for Intracranial Aneurysm

Sites in Greenville +6 more locations

Sponsor: Medtronic Neurovascular Clinical Affairs

Sex: All·Age: 22+

Code: NCT06604884·Recruiting·Listed Sep 2024

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A First-In-Human, Phase 1 Study Evaluating Oral TACC3 PPI Inhibitor, AO-252, in Advanced Solid Tumors With or Without Brain Metastases

for Solid Tumor Malignancies

Sites in Charleston +5 more locations

Sponsor: A2A Pharmaceuticals Inc.

Sex: All·Age: 18+

Code: NCT06136884·Phase 1·Recruiting·Listed Nov 2023

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Study of Patritumab Deruxtecan With Other Anticancer Agents in Participants With HER2 Positive Breast Cancer That Has Spread and Cannot Be Surgically Removed (MK-1022-009)

for Breast Neoplasms

Sites in Greenville +4 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06686394·Phase 1, Phase 2·Recruiting·Listed Nov 2024

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Real Life Evaluation of the LibAirty Airway Clearance System in Adults With Bronchiectasis (RELACS)

for Bronchiectasis Adult

Sites in Charleston +2 more locations

Sponsor: Synchrony-Medical, Ltd

Sex: All·Age: 21+

Code: NCT07135284·Recruiting·Listed Aug 2025

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Post Market Study for VasQ, an External Support Implant for Arteriovenous Fistula

for End Stage Renal Disease

Sites in Columbia +7 more locations

Sponsor: Laminate Medical Technologies

Sex: All·Age: 18 - 80

Code: NCT06516653·Recruiting·Listed Jul 2024

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Evaluation of Neoadjuvant Xaluritamig in Localized Prostate Cancer

for Prostate Cancer

Sites in Myrtle Beach +6 more locations

Sponsor: Amgen

Sex: Male·Age: 18+

Code: NCT06613100·Phase 1·Recruiting·Listed Sep 2024

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A Study to Evaluate the Safety and Efficacy of BEAM-302 in Adult Patients With Alpha-1 Antitrypsin Deficiency (AATD)

for Alpha 1-Antitrypsin Deficiency

Sites in Charleston +2 more locations

Sponsor: Beam Therapeutics Inc.

Sex: All·Age: 18 - 70

Code: NCT06389877·Phase 1, Phase 2·Recruiting·Listed Apr 2024

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Contour Neurovascular System™ ContiNued Access Investigational Device EXempTion (IDE) Trial (NEXT Trial)

for Cerebral Aneurysms

Sites in Charleston +8 more locations

Sponsor: Cerus Endovascular, Inc.

Sex: All·Age: 18 - 75

Code: NCT06693011·Recruiting·Listed Nov 2024

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An Engineered Sirpα Fused to Anti-Pd-L1 And Tgf-β Fusion Protein (HCB301) in Subjects With Selected Advanced Tumors

for Advanced Solid Tumor

1 location in Greenville

Sponsor: FBD Biologics Limited

Sex: All·Age: 18+

Code: NCT06487624·Phase 1·Recruiting·Listed Jul 2024

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Phase 1 Study of ACE-232 to Treat Patients With Metastatic Castration-Resistant Prostate Cancer

for Prostate Cancer (Adenocarcinoma)

Sites in Myrtle Beach +7 more locations

Sponsor: Acerand Therapeutics (Hong Kong) Limited

Sex: Male·Age: 18+

Code: NCT06801236·Phase 1·Recruiting·Listed Jan 2025

Apply to this trial

MiREA-AC for Reducing Problematic Alcohol and Marijuana Use in College Students

for Alcohol Misuse

Sites in Columbia +1 more location

Sponsor: mHealth Systems Inc.

Sex: All·Age: 18 - 26·Accepts healthy volunteers

Code: NCT07339150·Recruiting·Listed Jan 2026

Apply to this trial

Development of Optical Biometer

for Cataract and IOL Surgery

1 location in Hilton Head Island

Sponsor: Cassini Technologies

Sex: All·Age: 18+

Code: NCT07325162·Recruiting·Listed Jan 2026

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EndoForce Post Approval Study

for End Stage Renal Disease (ESRD)

Sites in Spartanburg & Orangeburg

Sponsor: Phraxis, Inc.

Sex: All·Age: 18+

Code: NCT07146854·Recruiting·Listed Aug 2025

Apply to this trial