Paid Clinical Trials in South Carolina

South Carolina has 1,226 paid clinical trials enrolling now across cities including Charleston, Greenville and Columbia. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 31, 2026.

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1,109 clinical trials

A Study Using Nivolumab, in Combination With Chemotherapy Drugs to Treat Nasopharyngeal Carcinoma (NPC)

for Stage II Nasopharyngeal Carcinoma AJCC v8

Drug: Nivolumab

Sites in Greenville, Columbia +73 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 21

Code: NCT06064097·Phase 2·Recruiting·Listed Oct 2023

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Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)

for Recurrent Lung Non-Small Cell Carcinoma

Drug: Cemiplimab

Sites in Charleston, Spartanburg +379 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06616584·Phase 2, Phase 3·Recruiting·Listed Sep 2024

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Intraoperative Molecular Imaging Using ICG for Head and Neck Tumors

for Squamous Cell Carcinoma Head and Neck Cancer (HNSCC)

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT07149207·Phase 2·Recruiting·Listed Aug 2025

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A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss

for Childhood Medulloblastoma

Sites in Greenville, Columbia +99 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 4 - 21

Code: NCT05382338·Phase 3·Recruiting·Listed May 2022

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Testing the Addition of Venetoclax or Gemtuzumab Ozogamicin (GO) to Usual Treatment Regimen (Cytarabine and Daunorubicin, "7+3") for Core Binding Factor Acute Myeloid Leukemia (CBF-AML) to Improve Response (A MYELOMATCH Treatment Trial)

for Core Binding Factor Acute Myeloid Leukemia

Drug: Venetoclax

Sites in Greenville, Greer +34 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 59

Code: NCT06917911·Phase 2·Recruiting·Listed Apr 2025

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Standardizing Treatments for Pulmonary Exacerbations - Aminoglycoside Study

for Cystic Fibrosis

Sites in Charleston +58 more locations

Sponsor: Chris Goss

Sex: All·Age: 6+

Code: NCT05548283·Phase 4·Recruiting·Listed Sep 2022

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DECIDE: A Comparative Effectiveness Trial of Metformin Versus Insulin for the Treatment of Gestational Diabetes

for Gestational Diabetes Mellitus

Sites in Greenville +20 more locations

Sponsor: Ohio State University

Sex: Female·Age: 18+

Code: NCT06445946·Phase 4·Recruiting·Listed Jun 2024

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Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

for Cognitive Impairment, Mild

Sites in Charleston, Columbia +89 more locations

Sponsor: Duke University

Sex: All·Age: 75+·Accepts healthy volunteers

Code: NCT04262206·Phase 4·Recruiting·Listed Feb 2020

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The Society for Obstetric Anesthesia and Perinatology Research Network General Anesthesia Registry

for Cesarean Delivery

Sites in Charleston +32 more locations

Sponsor: Yale University

Sex: Female·Age: 15 - 55·Accepts healthy volunteers

Code: NCT06030063·Recruiting·Listed Sep 2023

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Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)

for Recurrent Lung Non-Small Cell Carcinoma

Sites in Anderson +240 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18 Minutes+

Code: NCT06031688·Phase 2·Recruiting·Listed Sep 2023

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Primary Subtalar Arthrodesis for Calcaneal Fractures

for Calcaneus Fracture

Sites in Greenville +16 more locations

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT06249126·Recruiting·Listed Feb 2024

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Rett Syndrome Registry

for Rett Syndrome

Sites in Greenwood +18 more locations

Sponsor: International Rett Syndrome Foundation

Sex: All·Age: 0 - 99

Code: NCT05432349·Recruiting·Listed Jun 2022

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S1703 Serum Tumor Marker Directed Disease Monitoring in Patients With Hormone Receptor Positive Her2 Negative Metastatic Breast Cancer

for Anatomic Stage IV Breast Cancer AJCC v8

Sites in Greenville, Greer +584 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT03723928·Recruiting·Listed Oct 2018

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Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

for Coronavirus Infection (COVID-19)

Sites in Charleston +23 more locations

Sponsor: Duke University

Sex: All·Age: 0 - 20·Accepts healthy volunteers

Code: NCT04278404·Recruiting·Listed Feb 2020

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Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial

for Castration-Resistant Prostate Carcinoma

Sites in Spartanburg, Greer +100 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT06632977·Phase 2·Recruiting·Listed Oct 2024

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Recombinant Factor VIIa (rFVIIa) for Hemorrhagic Stroke Trial - Part 2

for Intracerebral Hemorrhage

Sites in Charleston, Greenville +46 more locations

Sponsor: Joseph Broderick, MD

Sex: All·Age: 18 - 80

Code: NCT07227246·Phase 3·Recruiting·Listed Nov 2025

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Phase 3 Study of Teclistamab in Combination With Lenalidomide and Teclistamab Alone Versus Lenalidomide Alone in Participants With Newly Diagnosed Multiple Myeloma as Maintenance Therapy Following Autologous Stem Cell Transplantation

for Multiple Myeloma

Drug: Teclistamab

Sites in Charleston, Spartanburg +39 more locations

Sponsor: European Myeloma Network B.V.

Sex: All·Age: 18+

Code: NCT05243797·Phase 3·Recruiting·Listed Feb 2022

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Accelerated rTMS vs. Sham for Stroke Apathy

for Apathy

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 40+

Code: NCT07113067·Phase 1, Phase 2·Recruiting·Listed Aug 2025

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Naxitamab Added to Induction for Newly Diagnosed High-Risk Neuroblastoma

for Neuroblastoma

Sites in Charleston +18 more locations

Sponsor: Giselle Sholler

Sex: All·Age: 12 Months - 21

Code: NCT05489887·Phase 2·Recruiting·Listed Aug 2022

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Streamlined Treatment of Pulmonary Exacerbations in Pediatrics

for Cystic Fibrosis

Sites in Charleston +30 more locations

Sponsor: University of Washington, the Collaborative Health Studies Coordinating Center

Sex: All·Age: 3 - 18

Code: NCT06654752·Recruiting·Listed Oct 2024

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Ribociclib And Endocrine Treatment of Physician's Choice for Locoregional Recurrent, Resected Hormone Receptor Positive HER2 Negative Breast Cancer

for Locoregional Recurrence

Drug: Ribociclib

Sites in Charleston +18 more locations

Sponsor: Oana Danciu

Sex: All·Age: 18+

Code: NCT05467891·Phase 2·Recruiting·Listed Jul 2022

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Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis- Magnetic Resonance Imaging

for Stroke

Sites in Columbia +27 more locations

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT05907629·Recruiting·Listed Jun 2023

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Electronic Cigarettes as a Harm Reduction Strategy Among People With Opioid Use Disorder on Buprenorphine

for Tobacco-flavored EC

1 location in Greenville

Sponsor: Prisma Health-Upstate

Sex: All·Age: 21+

Code: NCT07202039·Recruiting·Listed Oct 2025

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Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)

for Lung Non-Small Cell Carcinoma

Sites in Charleston +242 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06116682·Phase 2·Recruiting·Listed Nov 2023

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Prevention of Ototoxicity in NTM Patients Treated With IV Amikacin

for Ototoxicity, Drug-Induced

Sites in Charleston +7 more locations

Sponsor: Kevin Winthrop

Sex: All·Age: 18 - 80

Code: NCT05730283·Phase 2·Recruiting·Listed Feb 2023

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Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors

for Colorectal Cancer Stage II

Sites in Charleston, Greenville +373 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07018869·Phase 3·Recruiting·Listed Jun 2025

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Anticoagulation in ICH Survivors for Stroke Prevention and Recovery

for Intracerebral Hemorrhage

Sites in Charleston, Greenville +140 more locations

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT03907046·Phase 3·Recruiting·Listed Apr 2019

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Neural Bases of Vocal Sensorimotor Impairment in Aphasia

for Aphasia

Sites in Columbia +2 more locations

Sponsor: The University of Texas at Dallas

Sex: All·Age: 21 - 75·Accepts healthy volunteers

Code: NCT04742894·Recruiting·Listed Feb 2021

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GLP1 Fasting Status and Gastric Retention Using Gastric Ultrasound

for Gastric Retention

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT07251803·Recruiting·Listed Nov 2025

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Improving Needs Among Older Adults

for Critical Illness

Sites in Charleston +3 more locations

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT06588556·Recruiting·Listed Sep 2024

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Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer

for Fallopian Tube Endometrioid Adenocarcinoma

Drug: Bevacizumab

Sites in Spartanburg, Greer +643 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT06580314·Phase 3·Recruiting·Listed Aug 2024

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Advanced SPinal Innovations With Robotics and Enabling Technology Registry

for Spine Deformity

Sites in Charleston +9 more locations

Sponsor: Boston Children's Hospital

Sex: All·Age: 0 - 21·Accepts healthy volunteers

Code: NCT05071144·Recruiting·Listed Oct 2021

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Combining rTMS & Aerobic Exercise to Treat Depression and Improve Post-Stroke Walking

for Stroke

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 21 - 70

Code: NCT07050355·Recruiting·Listed Jul 2025

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Nephrotic Syndrome Study Network

for Minimal Change Disease (MCD)

Sites in Charleston +33 more locations

Sponsor: University of Michigan

Sex: All·Age: Up to 80

Code: NCT01209000·Recruiting·Listed Sep 2010

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Pulmonary Embolism - Thrombus Removal With Catheter-Directed Therapy

for Pulmonary Embolism

Sites in Charleston +39 more locations

Sponsor: NYU Langone Health

Sex: All·Age: 18+

Code: NCT05591118·Phase 3·Recruiting·Listed Oct 2022

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Evaluation of Tirzepatide as an Adjunct to Buprenorphine for the Treatment of Opioid Use Disorder

for Opioid Use Disorder

Drug: Tirzepatide

Sites in Greenville +8 more locations

Sponsor: T. John Winhusen, PhD

Sex: All·Age: 18+

Code: NCT06651177·Phase 2·Recruiting·Listed Oct 2024

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Project: Every Child for Younger Patients With Cancer

for Adrenal Gland Pheochromocytoma

Sites in Charleston, Greenville +231 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 25

Code: NCT02402244·Recruiting·Listed Mar 2015

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Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML)

for Acute Myeloid Leukemia

Drug: Venetoclax

Sites in Columbia +44 more locations

Sponsor: PedAL BCU, LLC

Sex: All·Age: 29 Days - 21

Code: NCT05183035·Phase 3·Recruiting·Listed Jan 2022

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Optimizing Pain Treatment in Children On Mechanical Ventilation

for Mechanical Ventilation

Sites in Charleston +15 more locations

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 2 Months - 17

Code: NCT06994442·Phase 3·Recruiting·Listed May 2025

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A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT

for Anaplastic Kidney Wilms Tumor

Sites in Charleston, Greenville +169 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 30

Code: NCT04322318·Phase 2·Recruiting·Listed Mar 2020

Apply to this trial