Paid Clinical Trials in South Carolina

South Carolina has 1,217 paid clinical trials enrolling now across cities including Charleston, Greenville and Columbia. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 14, 2026.

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1,101 clinical trials

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Platform Clinical Study for Conquering Scleroderma

for Interstitial Lung Disease Due to Systemic Disease

Sites in Charleston +23 more locations

Sponsor: Scleroderma Research Foundation, Inc.

Sex: All·Age: 18+

Code: NCT06195072·Phase 2·Recruiting·Listed Jan 2024

Apply to this trial

COPEWeb Training for Providers

for PTSD

1 location in Charleston

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05812131·Recruiting·Listed Apr 2023

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Optimizing Pain Treatment in Children On Mechanical Ventilation

for Mechanical Ventilation

Sites in Charleston +15 more locations

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 2 Months - 17

Code: NCT06994442·Phase 3·Recruiting·Listed May 2025

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Biologics in Chronic Rhinosinusitis With Nasal Polyposis

for Chronic Sinusitis

Sites in Charleston +1 more location

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT06824649·Phase 4·Recruiting·Listed Feb 2025

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Surgical Thromboprophylaxis Practices in Oncology Patients Within the NCORP Network, STOP-VTE Study

for Malignant Digestive System Neoplasm

Sites in Charleston, Greenville +56 more locations

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07215624·Recruiting·Listed Oct 2025

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Accelerated rTMS vs. Sham for Stroke Apathy

for Apathy

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 40+

Code: NCT07113067·Phase 1, Phase 2·Recruiting·Listed Aug 2025

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Systemic Lupus Erythematosus in Gullah Health

for Systemic Lupus Erythematosus

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 2+·Accepts healthy volunteers

Code: NCT00756769·Recruiting·Listed Sep 2008

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Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)

for Lung Non-Small Cell Carcinoma

Sites in Charleston +242 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06116682·Phase 2·Recruiting·Listed Nov 2023

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Behavioral Activation Delivered Via Home-based Telehealth to Improve Functioning in Cardiovascular Disease Patients Recently Discharged From Inpatient Care

for Depression

1 location in Charleston

Sponsor: VA Office of Research and Development

Sex: All·Age: 21+

Code: NCT04877197·Recruiting·Listed May 2021

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Finding the Best Tamoxifen Dose for Breast Cancer Risk Reduction in Premenopausal Women, RENAISSANCE Trial

for Breast Atypical Ductal Hyperplasia

Sites in Charleston +9 more locations

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18 - 55

Code: NCT06184750·Phase 2·Recruiting·Listed Dec 2023

Apply to this trial

Precision Rehabilitation for Veterans With (HFpEF)

for Heart Failure

1 location in Columbia

Sponsor: Columbia VA Health Care System

Sex: All·Age: 18+

Code: NCT07493915·Recruiting·Listed Mar 2026

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Advanced SPinal Innovations With Robotics and Enabling Technology Registry

for Spine Deformity

Sites in Charleston +9 more locations

Sponsor: Boston Children's Hospital

Sex: All·Age: 0 - 21·Accepts healthy volunteers

Code: NCT05071144·Recruiting·Listed Oct 2021

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Efficacy of Intramuscular Steroid Injection for Chronic Cough.

for Chronic Cough (CC)

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT06634823·EARLY_Phase 1·Recruiting·Listed Oct 2024

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Healing, Equity, Advocacy and Respect for Mamas

for Postpartum Complication

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: Female·Age: 16 - 49

Code: NCT06273436·Recruiting·Listed Feb 2024

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Impact of Cigarette and E-cigarette Menthol Regulation on Current Smokers of Menthol Cigarettes

for Smoking Prevention and Control

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT05896033·Recruiting·Listed Jun 2023

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RECOVERS - Realigning Emotion and COgnition Via prEcision Regulation networkS

for Depression

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT05977439·Recruiting·Listed Aug 2023

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Nephrotic Syndrome Study Network

for Minimal Change Disease (MCD)

Sites in Charleston +33 more locations

Sponsor: University of Michigan

Sex: All·Age: Up to 80

Code: NCT01209000·Recruiting·Listed Sep 2010

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Randomized Trial Comparing Immediate vs. Deferred Surgery for Symptomatic ERM

for Epiretinal Membrane

Sites in Hilton Head Island +46 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 50+

Code: NCT05145491·Recruiting·Listed Dec 2021

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CGM for Management of Type 2 Diabetes in Pregnancy

for Type 2 Diabetes Mellitus (T2DM)

Sites in Greenville +6 more locations

Sponsor: University of Alabama at Birmingham

Sex: Female·Age: 18 - 50

Code: NCT06628453·Recruiting·Listed Oct 2024

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Hypofractionated Radiotherapy With a Focal Microboost for High-Risk and Locally Advanced Prostate Cancer

for Prostate Cancer

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: Male·Age: 18+

Code: NCT07325721·Phase 2·Recruiting·Listed Jan 2026

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Anticoagulation in ICH Survivors for Stroke Prevention and Recovery

for Intracerebral Hemorrhage

Sites in Charleston, Greenville +140 more locations

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT03907046·Phase 3·Recruiting·Listed Apr 2019

Apply to this trial

Optimizing Care for Cancer Survivors With Depression: Project 3

for Cancer

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT06930729·Recruiting·Listed Apr 2025

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Pancreatic Cancer Detection Consortium

for Pancreatic Cancer

Sites in Rock Hill +8 more locations

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06388967·Recruiting·Listed Apr 2024

Apply to this trial

Switch or Quit R01

for Cigarette Smoking

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT06373679·Recruiting·Listed Apr 2024

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Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

for Breast Carcinoma

Sites in Charleston, Greenville +462 more locations

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT06418204·Recruiting·Listed May 2024

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Pulmonary Embolism - Thrombus Removal With Catheter-Directed Therapy

for Pulmonary Embolism

Sites in Charleston +39 more locations

Sponsor: NYU Langone Health

Sex: All·Age: 18+

Code: NCT05591118·Phase 3·Recruiting·Listed Oct 2022

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Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors

for Colorectal Cancer Stage II

Sites in Charleston, Greenville +373 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07018869·Phase 3·Recruiting·Listed Jun 2025

Apply to this trial

QL vs LAI for Palatoplasty

for Post-operative Pain

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 6 - 18

Code: NCT06420336·Recruiting·Listed May 2024

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Wrist Extensor MEP Up-conditioning for Individuals With Incomplete Spinal Cord Injury

for Spinal Cord Injuries

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT05321017·Recruiting·Listed Apr 2022

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Atomoxetine and Executive Function in PTSD

for Posttraumatic Stress Disorder With Attention Defic

1 location in Charleston

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT06573970·Phase 4·Recruiting·Listed Aug 2024

Apply to this trial

Young Adult Tobacco/Nicotine and Cannabis Co-use

for Tobacco Use Disorder

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18 - 25·Accepts healthy volunteers

Code: NCT06239350·Recruiting·Listed Feb 2024

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Evaluation of Low and High Nicotine Tobacco Free Nicotine Pouches

for Cigarette Smoking

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT06678789·Recruiting·Listed Nov 2024

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Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI

for Carcinoma, Hepatocellular

Sites in Charleston, Columbia +31 more locations

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 75

Code: NCT05486572·Recruiting·Listed Aug 2022

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Study of Orally Administered AG-120 in Subjects With Advanced Hematologic Malignancies With an IDH1 Mutation

for Relapsed or Refractory Acute Myeloid Leukemia (AML)

Sites in Charleston +2 more locations

Sponsor: Institut de Recherches Internationales Servier

Sex: All·Age: 18+

Code: NCT02074839·Phase 1·Recruiting·Listed Feb 2014

Apply to this trial

International Registry for Men With Advanced Prostate Cancer (IRONMAN)

for Prostate Cancer

Sites in Charleston +34 more locations

Sponsor: Prostate Cancer Clinical Trials Consortium

Sex: Male·Age: 21+

Code: NCT03151629·Recruiting·Listed May 2017

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The PIVATAL Study -Study of Ventricular Arrhythmia (VTA) Ablation in Left Ventricular Assist Device (LVAD) Patients

for Arrythmia

Sites in Charleston +18 more locations

Sponsor: University of Rochester

Sex: All·Age: 18+

Code: NCT05034432·Phase 4·Recruiting·Listed Sep 2021

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Prediction Augmented Screening Initiative

for Lung Cancer

Sites in Charleston +3 more locations

Sponsor: VA Office of Research and Development

Sex: All·Age: 50 - 80

Code: NCT06538636·Recruiting·Listed Aug 2024

Apply to this trial

Epilepsy Journey-An Executive Functioning Intervention for Teens With Epilepsy

for Epilepsy in Children

Sites in Charleston +2 more locations

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 13 - 17

Code: NCT06608966·Recruiting·Listed Sep 2024

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Induction in the Dark

for Anesthesia Induction

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 2 - 6

Code: NCT06144177·Phase 4·Recruiting·Listed Nov 2023

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CBD for Breast Cancer Primary Tumors

for Breast Cancer

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT06148038·Phase 1·Recruiting·Listed Nov 2023

Apply to this trial