Paid Clinical Trials in South Carolina

South Carolina has 1,226 paid clinical trials enrolling now across cities including Charleston, Greenville and Columbia. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 31, 2026.

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1,109 clinical trials

CGM for Management of Type 2 Diabetes in Pregnancy

for Type 2 Diabetes Mellitus (T2DM)

Sites in Greenville +6 more locations

Sponsor: University of Alabama at Birmingham

Sex: Female·Age: 18 - 50

Code: NCT06628453·Recruiting·Listed Oct 2024

Apply to this trial

Randomized Trial Comparing Immediate vs. Deferred Surgery for Symptomatic ERM

for Epiretinal Membrane

Sites in Hilton Head Island +46 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 50+

Code: NCT05145491·Recruiting·Listed Dec 2021

Apply to this trial

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

for Breast Carcinoma

Sites in Charleston, Greenville +462 more locations

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT06418204·Recruiting·Listed May 2024

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A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

for Ovarian Carcinoma

Sites in Charleston, Greenville +471 more locations

Sponsor: NRG Oncology

Sex: Female·Age: 35 - 50

Code: NCT04251052·Recruiting·Listed Jan 2020

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International Registry for Men With Advanced Prostate Cancer (IRONMAN)

for Prostate Cancer

Sites in Charleston +34 more locations

Sponsor: Prostate Cancer Clinical Trials Consortium

Sex: Male·Age: 21+

Code: NCT03151629·Recruiting·Listed May 2017

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Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

for Metastatic Malignant Neoplasm in the Lung

Sites in Charleston, Greenville +209 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 50

Code: NCT05235165·Phase 3·Recruiting·Listed Feb 2022

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A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)

for Stage I Mixed Cell Type Kidney Wilms Tumor

Sites in Greenville, Columbia +144 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 30

Code: NCT06401330·Phase 3·Recruiting·Listed May 2024

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Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI

for Carcinoma, Hepatocellular

Sites in Charleston, Columbia +31 more locations

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 75

Code: NCT05486572·Recruiting·Listed Aug 2022

Apply to this trial

Optimizing Care for Cancer Survivors With Depression: Project 3

for Cancer

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT06930729·Recruiting·Listed Apr 2025

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Study of Orally Administered AG-120 in Subjects With Advanced Hematologic Malignancies With an IDH1 Mutation

for Relapsed or Refractory Acute Myeloid Leukemia (AML)

Sites in Charleston +2 more locations

Sponsor: Institut de Recherches Internationales Servier

Sex: All·Age: 18+

Code: NCT02074839·Phase 1·Recruiting·Listed Feb 2014

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A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT

for Central Nervous System Nongerminomatous Germ Cell Tumor

Sites in Charleston, Greenville +132 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 3 - 29

Code: NCT04684368·Phase 2·Recruiting·Listed Dec 2020

Apply to this trial

Biologics in Chronic Rhinosinusitis With Nasal Polyposis

for Chronic Sinusitis

Sites in Charleston +1 more location

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT06824649·Phase 4·Recruiting·Listed Feb 2025

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Systemic Lupus Erythematosus in Gullah Health

for Systemic Lupus Erythematosus

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 2+·Accepts healthy volunteers

Code: NCT00756769·Recruiting·Listed Sep 2008

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Behavioral Activation Delivered Via Home-based Telehealth to Improve Functioning in Cardiovascular Disease Patients Recently Discharged From Inpatient Care

for Depression

1 location in Charleston

Sponsor: VA Office of Research and Development

Sex: All·Age: 21+

Code: NCT04877197·Recruiting·Listed May 2021

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Finding the Best Tamoxifen Dose for Breast Cancer Risk Reduction in Premenopausal Women, RENAISSANCE Trial

for Breast Atypical Ductal Hyperplasia

Sites in Charleston +9 more locations

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18 - 55

Code: NCT06184750·Phase 2·Recruiting·Listed Dec 2023

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Intravitreal Faricimab Injections or Fluocinolone Acetonide (0.19 mg) Intravitreal Implants vs Observation for Prevention of VA Loss Due to Radiation Retinopathy

for Radiation Retinopathy

Sites in Greenville +24 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 18+

Code: NCT05844982·Phase 3·Recruiting·Listed May 2023

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Tele-PCIT for Healthy Relationships in Families At-Risk

for Disruptive Behavior

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 2 - 7

Code: NCT07225010·Recruiting·Listed Nov 2025

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High Dose Testosterone for ATM, CDK12 or CHEK2 Altered Prostate Cancers

for Metastatic Prostate Cancer

Sites in Charleston +16 more locations

Sponsor: VA Office of Research and Development

Sex: Male·Age: 18+

Code: NCT05011383·Phase 2·Recruiting·Listed Aug 2021

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Efficacy of Intramuscular Steroid Injection for Chronic Cough.

for Chronic Cough (CC)

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT06634823·EARLY_Phase 1·Recruiting·Listed Oct 2024

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Healing, Equity, Advocacy and Respect for Mamas

for Postpartum Complication

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: Female·Age: 16 - 49

Code: NCT06273436·Recruiting·Listed Feb 2024

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Impact of Cigarette and E-cigarette Menthol Regulation on Current Smokers of Menthol Cigarettes

for Smoking Prevention and Control

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT05896033·Recruiting·Listed Jun 2023

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RECOVERS - Realigning Emotion and COgnition Via prEcision Regulation networkS

for Depression

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT05977439·Recruiting·Listed Aug 2023

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Pancreatic Cancer Detection Consortium

for Pancreatic Cancer

Sites in Rock Hill +8 more locations

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06388967·Recruiting·Listed Apr 2024

Apply to this trial

Switch or Quit R01

for Cigarette Smoking

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT06373679·Recruiting·Listed Apr 2024

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A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients With Heart Failure Who Are Intolerant or Not Eligible for Treatment With Steroidal Mineralocorticoid Receptor Antagonists

for Heart Failure

Drug: Finerenone

Sites in Orangeburg +53 more locations

Sponsor: Colorado Prevention Center

Sex: All·Age: 18+

Code: NCT06033950·Phase 3·Recruiting·Listed Sep 2023

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QL vs LAI for Palatoplasty

for Post-operative Pain

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 6 - 18

Code: NCT06420336·Recruiting·Listed May 2024

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Antibiotic Cement Bead Pouch Versus Negative Pressure Wound Therapy

for Open tíbia Fracture

Sites in Greenville, Columbia +25 more locations

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18+

Code: NCT05615844·Phase 3·Recruiting·Listed Nov 2022

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Wrist Extensor MEP Up-conditioning for Individuals With Incomplete Spinal Cord Injury

for Spinal Cord Injuries

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT05321017·Recruiting·Listed Apr 2022

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Atomoxetine and Executive Function in PTSD

for Posttraumatic Stress Disorder With Attention Defic

1 location in Charleston

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT06573970·Phase 4·Recruiting·Listed Aug 2024

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A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients

for Heart Failure

Drug: Finerenone

Sites in Charleston +79 more locations

Sponsor: Colorado Prevention Center

Sex: All·Age: 18+

Code: NCT06008197·Phase 3·Recruiting·Listed Aug 2023

Apply to this trial

Young Adult Tobacco/Nicotine and Cannabis Co-use

for Tobacco Use Disorder

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18 - 25·Accepts healthy volunteers

Code: NCT06239350·Recruiting·Listed Feb 2024

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A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia

for B Acute Lymphoblastic Leukemia Associated With Down Syndrome

Sites in Greenville, Columbia +67 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 6 - 39

Code: NCT05702645·Recruiting·Listed Jan 2023

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The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation

for Atrial Fibrillation

Sites in Charleston, Columbia +85 more locations

Sponsor: Johns Hopkins University

Sex: All·Age: 22 - 85

Code: NCT05836987·Phase 3·Recruiting·Listed May 2023

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Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM Study

for Extensive Stage Lung Small Cell Carcinoma

Sites in Greenville, Greer +144 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06769126·Phase 2·Recruiting·Listed Jan 2025

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Telerehabilitation In The Home After Stroke

for Stroke

Sites in Charleston +26 more locations

Sponsor: University of California, Los Angeles

Sex: All·Age: 18 - 80

Code: NCT06682429·Recruiting·Listed Nov 2024

Apply to this trial

Prediction Augmented Screening Initiative

for Lung Cancer

Sites in Charleston +3 more locations

Sponsor: VA Office of Research and Development

Sex: All·Age: 50 - 80

Code: NCT06538636·Recruiting·Listed Aug 2024

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Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma

for Pleuropulmonary Blastoma

Sites in Greenville +75 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT06647953·Phase 3·Recruiting·Listed Oct 2024

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The PIVATAL Study -Study of Ventricular Arrhythmia (VTA) Ablation in Left Ventricular Assist Device (LVAD) Patients

for Arrythmia

Sites in Charleston +18 more locations

Sponsor: University of Rochester

Sex: All·Age: 18+

Code: NCT05034432·Phase 4·Recruiting·Listed Sep 2021

Apply to this trial

Epilepsy Journey-An Executive Functioning Intervention for Teens With Epilepsy

for Epilepsy in Children

Sites in Charleston +2 more locations

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 13 - 17

Code: NCT06608966·Recruiting·Listed Sep 2024

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Comparing Cooling and/or Compression Approaches of Limbs for Prevention of Chemotherapy-Induced Peripheral Neuropathy

for Malignant Solid Neoplasm

Sites in Spartanburg, Greer +31 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05642611·Phase 3·Recruiting·Listed Dec 2022

Apply to this trial