Paid Clinical Trials in South Carolina

South Carolina has 1,217 paid clinical trials enrolling now across cities including Charleston, Greenville and Columbia. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 14, 2026.

Filter results

State

City

Recruitment status

Phase

Study type

Intervention

Condition

Sex

Age

Healthy volunteers only

1,101 clinical trials

Get a weekly email when new trials open in Charleston, SC.

Pulmonary Hemodynamics During Exercise - Research Network

for Pulmonary Circulation Diseases

Sites in Charleston +7 more locations

Sponsor: Medical University of Graz

Sex: All·Age: 18+

Code: NCT03954574·Recruiting·Listed May 2019

Apply to this trial

Mirikizumab Real World Protocol

for Ulcerative Colitis

Sites in Charleston +7 more locations

Sponsor: University of North Carolina, Chapel Hill

Sex: All·Age: 18+

Code: NCT06696014·Recruiting·Listed Nov 2024

Apply to this trial

Prospective Registry of Patients Undergoing Cardiac CT With NAEOTOM Alpha PCD-CT Before TAVI Procedure

for Coronary Artery Disease

1 location in Charleston

Sponsor: Semmelweis University

Sex: All·Age: 18+

Code: NCT07016477·Recruiting·Listed Jun 2025

Apply to this trial

A Randomized Crossover Trial of Bright Light Therapy in Crohn's Disease on Intestinal Barrier Homeostasis

for Inflammatory Bowel Disease

Sites in Charleston +1 more location

Sponsor: Rush University Medical Center

Sex: All·Age: 18+

Code: NCT05579392·Recruiting·Listed Oct 2022

Apply to this trial

Multi-Center Molecular Diagnosis and Host Response of Respiratory Viral Infections in Pediatric Transplant Recipients

for Hematopoietic Cell Transplant

Sites in Charleston +26 more locations

Sponsor: Arkansas Children's Hospital Research Institute

Sex: All·Age: Up to 18

Code: NCT05550298·Recruiting·Listed Sep 2022

Apply to this trial

HF2 Registry - Hemodynamic Frontiers in Heart Failure Registry

for Heart Failure

Sites in Columbia +11 more locations

Sponsor: University of Kansas Medical Center

Sex: All·Age: 18 - 100

Code: NCT06425848·Recruiting·Listed May 2024

Apply to this trial

Increasing Affordable Fruits and Vegetables for Families With Food Insecurity

for Diet

1 location in Columbia

Sponsor: University of South Carolina

Sex: All·Age: 2 - 10·Accepts healthy volunteers

Code: NCT06828445·Phase 1·Recruiting·Listed Feb 2025

Apply to this trial

Transdiagnostic Behavior Therapy Vs TAU for Adjustment Disorder Following Traumatic Event Exposure

for Adjustment Disorders

1 location in Charleston

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: 18+

Code: NCT06433271·Recruiting·Listed May 2024

Apply to this trial

Development of an mHealth Behavioral Sleep Medicine Intervention for Use During Medication Assisted Treatment for MOUD

for Opioid Use Disorder

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT06157840·Recruiting·Listed Dec 2023

Apply to this trial

Ivosidenib Plus Durvalumab and Gemcitabine/Cisplatin as First-Line Therapy in Participants With Locally Advanced or Metastatic Cholangiocarcinoma With an IDH1 Mutation

for Locally Advanced, Unresectable or Metastatic Cholangiocarcinoma With an IDH1 Mutation

Drug: Durvalumab

Sites in Spartanburg +7 more locations

Sponsor: Institut de Recherches Internationales Servier

Sex: All·Age: 18+

Code: NCT06501625·Phase 1, Phase 2·Recruiting·Listed Jul 2024

Apply to this trial

Physiological Responses to Heat Stress During High-risk Events

for Thermoregulation

Sites in Fort Jackson +1 more location

Sponsor: United States Army Research Institute of Environmental Medicine

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06907225·Recruiting·Listed Apr 2025

Apply to this trial

Healthy Kids Beyond the Bell: Investigating the Impact of After-School and Summer Programs

for Health Status Disparities

1 location in Columbia

Sponsor: University of South Carolina

Sex: All·Age: 5 - 12·Accepts healthy volunteers

Code: NCT05880901·Phase 2·Recruiting·Listed May 2023

Apply to this trial

Determining the Optimal Amount of Structured Environments for Healthy Kids

for Health Status Disparities

1 location in Columbia

Sponsor: University of South Carolina

Sex: All·Age: 5 - 12·Accepts healthy volunteers

Code: NCT06158594·Phase 2·Recruiting·Listed Dec 2023

Apply to this trial

The Pediatric Lupus Nephritis Mycophenolate Mofetil (PLUMM) Study

for Lupus Nephritis

Sites in Charleston +18 more locations

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 8 - 20

Code: NCT05538208·Phase 2·Recruiting·Listed Sep 2022

Apply to this trial

A Prospective Analysis of Long-Term Clinical Outcomes and 3D Spine Growth in Anterior Vertebral Body Tethering

for Scoliosis Idiopathic

Sites in Charleston +10 more locations

Sponsor: Pediatric Spine Foundation

Sex: All·Age: Up to 18

Code: NCT04914507·Recruiting·Listed Jun 2021

Apply to this trial

A Pilot Study of a Remote ADHD Monitoring Program

for Attention-deficit/Hyperactivity Disorder

Sites in Charleston +1 more location

Sponsor: IDeA States Pediatric Clinical Trials Network

Sex: All·Age: 5 - 11·Accepts healthy volunteers

Code: NCT06743425·Recruiting·Listed Dec 2024

Apply to this trial

Closed-loop rTMS-EEG During Visuomotor Integration.

for Visuomotor Skills

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT07249801·Recruiting·Listed Nov 2025

Apply to this trial

Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem or Local Occlusion Thrombectomy Trial

for Acute Ischemic Stroke

Sites in Charleston +50 more locations

Sponsor: Mercy Health Ohio

Sex: All·Age: 18 - 79

Code: NCT05611242·Phase 3·Recruiting·Listed Nov 2022

Apply to this trial

Pulmonary Hypertension Association Registry

for Pulmonary Arterial Hypertension

Sites in Anderson +51 more locations

Sponsor: Pulmonary Hypertension Association, Inc.

Sex: All·Age: 0+

Code: NCT04071327·Recruiting·Listed Aug 2019

Apply to this trial

Modulating Anxious Coping

for Anxiety Disorders

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18 - 65

Code: NCT04824105·Recruiting·Listed Apr 2021

Apply to this trial

Transcutaneous Electrical Nerve Stimulation for Pain Mitigation During Intrauterine Device Placement

for Pain

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: Female·Age: 18+

Code: NCT06991075·Recruiting·Listed May 2025

Apply to this trial

Arcuate Incisions With Light Adjustable Lens for Astigmatism Correction in Lens Surgery

for Astigmatism

Sites in Mt. Pleasant +1 more location

Sponsor: Center For Sight

Sex: All·Age: 21+

Code: NCT07140653·Phase 4·Recruiting·Listed Aug 2025

Apply to this trial

National Collaborative to Improve Care of Children With Complex Congenital Heart Disease

for Hypoplastic Left Heart Syndrome (HLHS)

Sites in Charleston +58 more locations

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: Up to 15 Months

Code: NCT02852031·Recruiting·Listed Aug 2016

Apply to this trial

VIBRANT: VIB4920 for Active Lupus Nephritis

for Lupus Nephritis

Sites in Charleston +16 more locations

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18+

Code: NCT05201469·Phase 2·Recruiting·Listed Jan 2022

Apply to this trial

Intracervical Vasopressin

for Retained Products of Conception

1 location in Greenville

Sponsor: Prisma Health-Upstate

Sex: Female·Age: 18 - 51

Code: NCT07102615·Phase 4·Recruiting·Listed Aug 2025

Apply to this trial

Preoperative Acetazolamide

for Post Operative Pain

1 location in Greenville

Sponsor: Prisma Health-Upstate

Sex: Female·Age: 21 - 65

Code: NCT07101250·Phase 4·Recruiting·Listed Aug 2025

Apply to this trial

APPROVE Trial: Evaluating a Prescription Digital Therapeutic for Treatment of OAB in Women

for Overactive Bladder (OAB)

Sites in Charleston +8 more locations

Sponsor: Medstar Health Research Institute

Sex: Female·Age: 22+

Code: NCT06797245·Recruiting·Listed Jan 2025

Apply to this trial

Accelerated TMS for Seizure-Type Functional Neurologic Disorders

for Functional Neurological Symptom Disorder

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18 - 65

Code: NCT07059325·EARLY_Phase 1·Recruiting·Listed Jul 2025

Apply to this trial

Comparison of Two Different Sperm Processing Methods and Their Effects on Sperm DNA Fragmentation and Embryo Development

for DNA Damage

1 location in Greenville

Sponsor: Richard Kordus, PhD, HCLD (ABB)

Sex: All·Age: 18 - 34·Accepts healthy volunteers

Code: NCT06990841·Recruiting·Listed May 2025

Apply to this trial

Evaluation of Trauma Center-Based Intervention for Adolescent Traumatic Injury Survivors

for Traumatic Injury

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 12 - 17·Accepts healthy volunteers

Code: NCT05086757·Recruiting·Listed Oct 2021

Apply to this trial

Suvorexant: A Dual Orexin Receptor Antagonist for Treating Sleep Disturbance in Posttraumatic Stress

for Sleep Initiation and Maintenance Disorders

Sites in Charleston +3 more locations

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 75

Code: NCT03642028·Phase 4·Recruiting·Listed Aug 2018

Apply to this trial

Implementation Supports for Improving Identification and Delivery of School-based Mental Health Supports for Middle Schools Students

for Mental Health Issue

Sites in Columbia +2 more locations

Sponsor: University of Virginia

Sex: All·Age: 10 - 99·Accepts healthy volunteers

Code: NCT06047041·Recruiting·Listed Sep 2023

Apply to this trial

Electrical DN as an Adjunct to Eccentric Exercise, Stretching + MT for Achilles Tendinopathy

for Achilles Tendinopathy

1 location in Columbia

Sponsor: Alabama Physical Therapy & Acupuncture

Sex: All·Age: 18+

Code: NCT03968614·Recruiting·Listed May 2019

Apply to this trial

Improving the Collaborative Health of Minority COVID-19 Survivor and Carepartner Dyads

for SARS- CoV-2

1 location in Columbia

Sponsor: University of South Carolina

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05370014·Recruiting·Listed May 2022

Apply to this trial

Near Infrared Spectroscopy (NIRS) as a Method for Measuring Oxidative Capacity of Skeletal Muscle Mitochondria in Breast Cancer and All Gynecological Cancer Patients

for Breast Cancer

1 location in Greenville

Sponsor: University of South Carolina

Sex: Female·Age: 20+

Code: NCT06672497·Recruiting·Listed Nov 2024

Apply to this trial

Core Semantic Systems TMS

for Lexical Access in Neurotypicals

1 location in Columbia

Sponsor: University of South Carolina

Sex: All·Age: 18 - 40·Accepts healthy volunteers

Code: NCT06870552·Recruiting·Listed Mar 2025

Apply to this trial

Galactagogue Use in Lactating Women With Low Milk Supply

for Breast Milk Expression

1 location in Rock Hill

Sponsor: Winthrop University

Sex: Female·Age: 18 - 40·Accepts healthy volunteers

Code: NCT05398367·Recruiting·Listed Jun 2022

Apply to this trial

Blood Warming in Preterm Infants to Decrease Hypothermia

for Preterm Birth

1 location in Columbia

Sponsor: University of South Carolina

Sex: All·Age: 24 Weeks - 32 Weeks·Accepts healthy volunteers

Code: NCT05170633·Recruiting·Listed Dec 2021

Apply to this trial

A Research Study to Compare Two Different Versions of Injectable Cagrilintide and Placebo in People With Excess Body Weight

for Overweight

Sites in North Charleston +10 more locations

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07745504·Phase 3·Recruiting·Listed Aug 4, 2026

Apply to this trial

A Phase II Study of Biomarker-Guided De-escalation Using Anthracycline-Free Neoadjuvant Chemoimmunotherapy in Early-Stage Triple Negative Breast Cancer (TNBC) Patients With High Tumor-Infiltrating Lymphocytes (TILs)

for Triple Negative Breast Cancer (TNBC)

Sites in Charleston +1 more location

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT07743190·Phase 2·Recruiting·Listed Aug 3, 2026

Apply to this trial