Paid Clinical Trials in South Carolina

South Carolina has 1,217 paid clinical trials enrolling now across cities including Charleston, Greenville and Columbia. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 14, 2026.

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1,101 clinical trials

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A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes

for Obesity

Sites in Columbia, Gaffney +83 more locations

Sponsor: Ascletis Pharma (China) Co., Limited

Sex: All·Age: 18+

Code: NCT07743450·Phase 3·Recruiting·Listed Aug 3, 2026

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A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities

for Obesity

Sites in Columbia, Bluffton +65 more locations

Sponsor: Ascletis Pharma (China) Co., Limited

Sex: All·Age: 18+

Code: NCT07743463·Phase 3·Recruiting·Listed Aug 3, 2026

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A Study to Evaluate the Efficacy and Safety of Tabirafusp Tedromer Compared to Aflibercept in Participants With DME - ALTO

for Diabetic Macular Edema (DME)

Drug: Aflibercept

Sites in Charleston, West Columbia +7 more locations

Sponsor: Kodiak Sciences Inc

Sex: All·Age: 18+

Code: NCT07734844·Phase 3·Recruiting·Listed Jul 29, 2026

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An Open-Label, Single-Arm Study to Investigate the Efficacy and Safety of North Star Desiccated Porcine Thyroid Extract Tablets.

for Hypothyroidism

Sites in Charleston, North Charleston +23 more locations

Sponsor: Neuvosyn Laboratories, LLC

Sex: All·Age: 18 - 75

Code: NCT07747103·Phase 3·Recruiting·Listed Aug 5, 2026

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Specimen and Data Collection in South Carolina Medicaid-Enrolled Patients With Type 2 Diabetes (T2D) and Metabolically Healthy Controls

for Type 2 Diabetes

Sites in Orangeburg & Walhalla

Sponsor: Guardian Research Network, Inc.

Sex: All·Age: 40 - 70·Accepts healthy volunteers

Code: NCT07731399·Recruiting·Listed Jul 28, 2026

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Forward Treatment of Attention Deficit and Hyperactivity Using Solriamfetol (FOCUS-2)

for ADHD

Drug: Solriamfetol

Sites in North Charleston +22 more locations

Sponsor: Axsome Therapeutics, Inc.

Sex: All·Age: 6 - 11

Code: NCT07717879·Phase 3·Recruiting·Listed Jul 21, 2026

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Forward Treatment of Attention Deficit and Hyperactivity Using Solriamfetol (FOCUS-3)

for ADHD

Drug: Solriamfetol

Sites in North Charleston +23 more locations

Sponsor: Axsome Therapeutics, Inc.

Sex: All·Age: 12 - 17

Code: NCT07717892·Phase 3·Recruiting·Listed Jul 21, 2026

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Phase 1/2 Study of Respiratory Syncytial Virus and Human Metapneumovirus (RSV+HMPV) Vaccine Candidate in Adults 60 Years of Age and Older

for Respiratory Syncytial Virus Immunization

Sites in North Charleston +16 more locations

Sponsor: Sanofi

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT07734649·Phase 1, Phase 2·Recruiting·Listed Jul 29, 2026

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A Study to Investigate Canvuparatide Compared With Placebo in Adult Patients With Hypoparathyroidism

for Hypoparathyroidism

Sites in Summerville +11 more locations

Sponsor: MBX Biosciences

Sex: All·Age: 18+

Code: NCT07699471·Phase 3·Recruiting·Listed Jul 2026

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A Study in Patients With Metastatic Castration-Resistant Prostate Cancer

for Metastatic Castration Resistant Prostate Cancer

Sites in Myrtle Beach +9 more locations

Sponsor: Flare Therapeutics Inc.

Sex: Male·Age: 18+

Code: NCT07719361·Phase 1·Recruiting·Listed Jul 22, 2026

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Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)

for Obesity

Sites in Greenville +69 more locations

Sponsor: Amgen

Sex: All·Age: 18 - 99

Code: NCT07684235·Phase 3·Recruiting·Listed Jul 2026

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An Open-label Study to Investigate the Efficacy and Safety of Dato-DXd + Rilvegostomig vs SoC in Adult Participants With High-risk MIUC

for High-risk Muscle Invasive Urothelial Carcinoma

Drug: Rilvegostomig

Sites in Myrtle Beach +17 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07720284·Phase 3·Recruiting·Listed Jul 22, 2026

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Study of Chemosensory Enhancement Through Neuromodulation Training (SCENT): Open Label

for Olfactory Impairment

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18 - 80

Code: NCT07689773·Phase 2·Recruiting·Listed Jul 2026

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A Long-Term Safety Study of Elismetrep (K-304) in the Acute Treatment of Migraine

for Acute Migraine

Drug: Elismetrep

Sites in North Charleston +112 more locations

Sponsor: Kallyope Inc.

Sex: All·Age: 18+

Code: NCT07674654·Phase 3·Recruiting·Listed Jun 2026

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A Master Protocol to Investigate Efficacy and Safety of Elecoglipron in Participants With Obesity or Overweight With or Without T2DM

for Weight Management

Sites in Charleston, Gaffney +53 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07667803·Phase 3·Recruiting·Listed Jun 2026

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An Extension Study to Assess Safety and Efficacy of Remibrutinib in Participants With Moderate to Severe HS

for Hidradenitis Suppurativa

Drug: Remibrutinib

Sites in Charleston +12 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 100

Code: NCT07665437·Phase 3·Recruiting·Listed Jun 2026

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A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus and Impaired Renal Function on Background Dapagliflozin

for Type 2 Diabetes Mellitus

Drug: Dapagliflozin

Sites in Greenville, Gaffney +28 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07662135·Phase 3·Recruiting·Listed Jun 2026

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A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Alone or in Combination With Dapagliflozin Compared With Placebo in Adults With Type 2 Diabetes Mellitus

for Type 2 Diabetes Mellitus

Drug: Dapagliflozin

Sites in Anderson +23 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07662044·Phase 3·Recruiting·Listed Jun 2026

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A Study to Find Out if the Study Drug Elecoglipron Helps Adults With Type 2 Diabetes Mellitus by Comparing it With Semaglutide, a Medicine Already Used to Treat Type 2 Diabetes Mellitus

for Type 2 Diabetes Mellitus

Drug: Semaglutide

Sites in Myrtle Beach, North Charleston +62 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07662213·Phase 3·Recruiting·Listed Jun 2026

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A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus on Background Insulin

for Type 2 Diabetes Mellitus

Sites in Myrtle Beach +14 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07664553·Phase 3·Recruiting·Listed Jun 2026

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A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)

for Obesity

Sites in Greer +73 more locations

Sponsor: Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics

Sex: All·Age: 18 - 79·Accepts healthy volunteers

Code: NCT07654374·Phase 3·Recruiting·Listed Jun 2026

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A Study of TAK-360 in People With Narcolepsy or Idiopathic Hypersomnia

for Idiopathic Hypersomnia

Sites in Columbia +8 more locations

Sponsor: Takeda

Sex: All·Age: 18 - 71

Code: NCT07646678·Phase 2, Phase 3·Recruiting·Listed Jun 2026

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Cryoablation for Monomorphic Ventricular Tachycardia (VTS)

for Ventricular Tachycardia, Sustained

Sites in Charleston +7 more locations

Sponsor: Adagio Medical

Sex: All·Age: 18+

Code: NCT07650032·Recruiting·Listed Jun 2026

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Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1)

for Obesity

Sites in Greer +70 more locations

Sponsor: Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics

Sex: All·Age: 18 - 79

Code: NCT07654361·Phase 3·Recruiting·Listed Jun 2026

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Buprenorphine Implementation at Syringe Service Programs to Reduce Overdoses

for Opioid Use Disorder

Sites in Greenville +7 more locations

Sponsor: Montefiore Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07631598·Recruiting·Listed Jun 2026

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DReAMzz- Dronabinol and Acetazolamide Medication for Sleep Apnea (ZZ). Dose Confirmation Crossover Study for IHL-42X in Subjects With Obstructive Sleep Apnea.

for Obstructive Sleep Apnea (OSA)

Sites in Anderson +13 more locations

Sponsor: Incannex Healthcare Ltd

Sex: All·Age: 18 - 65

Code: NCT07635563·Phase 2·Recruiting·Listed Jun 2026

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A Phase III Study to Assess the Effect of FDC Laroprovstat/Rosuvastatin Compared With Laroprovstat, Rosuvastatin and Placebo on LDL-C in LLT-naïve Patients.

for Hypercholesterolaemia

Sites in Anderson +76 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT07619131·Phase 3·Recruiting·Listed Jun 2026

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A Study to Compare Elritercept to Placebo in Adults With Myelofibrosis and Anemia Who Are Taking Ruxolitinib

for Myelofibrosis

Drug: Ruxolitinib

Sites in Charleston +29 more locations

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT07623161·Phase 3·Recruiting·Listed Jun 2026

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AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)

for Metastatic Castration-resistant Prostate Cancer

Sites in Myrtle Beach +24 more locations

Sponsor: AstraZeneca

Sex: Male·Age: 18+

Code: NCT07611110·Phase 3·Recruiting·Listed May 2026

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A Phase IIb Study to Evaluate AZD8965 in Participants With IPF.

for Idiopathic Pulmonary Fibrosis (IPF)

Sites in Charleston +34 more locations

Sponsor: AstraZeneca

Sex: All·Age: 40+

Code: NCT07652658·Phase 2·Recruiting·Listed Jun 2026

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A Study to Assess the Safety, Tolerability and Efficacy of ION775

for Hypertriglyceridemia

Sites in Little River +15 more locations

Sponsor: Ionis Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT07604974·Phase 2·Recruiting·Listed May 2026

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A Study to Identify and Characterize Patients With Type 2 Diabetes Mellitus for Possible Participation in Ongoing or Future Type 2 Diabetes Mellitus Clinical Studies

for Type 2 Diabetes

Sites in Gaffney +13 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07606066·Recruiting·Listed May 2026

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BOND: Direct Breastfeeding to Enhance Maternal and Infant Health in Congenital Heart Disease

for Congenital Heart Disease (CHD)

Sites in Charleston +16 more locations

Sponsor: Carelon Research

Sex: All·Age: 18+

Code: NCT07582848·Recruiting·Listed May 2026

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Prenatally-initiated Psychological Intervention for Mothers of Infants With Congenital Heart Disease (CHD)

for Congenital Heart Disease (CHD)

Sites in Charleston +16 more locations

Sponsor: Carelon Research

Sex: All·Age: 18+

Code: NCT07582861·Recruiting·Listed May 2026

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GBPDC: Gut-Brain in PD Consortium Master Protocol

for Parkinson Disease (PD)

Sites in Charleston +6 more locations

Sponsor: Duke University

Sex: All·Age: 21 - 80·Accepts healthy volunteers

Code: NCT07567794·Recruiting·Listed May 2026

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Study of JANX014 in Subjects With Metastatic Castration-Resistant Prostate Cancer

for Prostate Cancer

Sites in Charleston, Greenville +4 more locations

Sponsor: Janux Therapeutics

Sex: Male·Age: 18+

Code: NCT07545811·Phase 1·Recruiting·Listed Apr 2026

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A Study to Evaluate the Efficacy, Safety and Tolerability of ALKS 2680 in Adults With Narcolepsy Type 1 (Brilliance NT1 - 304)

for Narcolepsy Type 1

Drug: ALKS 2680

Sites in Colombia +13 more locations

Sponsor: Alkermes, Inc.

Sex: All·Age: 18 - 70

Code: NCT07540897·Phase 3·Recruiting·Listed Apr 2026

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A Phase 3 Study to Evaluate the Efficacy and Safety of Samelisant in Patients With Narcolepsy (AWAKE)

for Narcolepsy

1 location in Columbia

Sponsor: Suven Life Sciences Limited

Sex: All·Age: 18+

Code: NCT07540364·Phase 3·Recruiting·Listed Apr 2026

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A Clinical Study to Evaluate the Efficacy and Safety of Frevecitinib (KN-002) in Patients With Severe Asthma

for Severe Asthma

Drug: Frevecitinib

Sites in Rock Hill +13 more locations

Sponsor: Kinaset Therapeutics Inc

Sex: All·Age: 18 - 75

Code: NCT07532265·Phase 2·Recruiting·Listed Apr 2026

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A Study to Evaluate the Efficacy and Safety of ALKS 2680 in Adults With Narcolepsy Type 2

for Narcolepsy Type 2

Drug: ALKS 2680

Sites in Columbia +21 more locations

Sponsor: Alkermes, Inc.

Sex: All·Age: 18 - 70

Code: NCT07502443·Phase 3·Recruiting·Listed Mar 2026

Apply to this trial