Paid Clinical Trials in South Carolina

South Carolina has 1,283 paid clinical trials enrolling now across cities including Charleston, Greenville and Columbia. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 17, 2026.

Filter results

State

City

Phase

Study type

Intervention

Recruitment status

Condition

Sex

Age

Healthy volunteers only

1,283 clinical trials

↓ Download CSV

A Study of BLB-201 RSV Vaccine in Infants and Children

for Respiratory Syncytial Virus Infections

15 locations incl. La Mesa

Sponsor: Blue Lake Biotechnology Inc.

Sex: All·Age: 6 Months - 5·Accepts healthy volunteers

Code: NCT05655182·Phase 1, Phase 2·Recruiting

Apply to this trial

A Study to Assess the Long-Term Safety and Efficacy of Lebrikizumab (LY3650150) in Participants 6 Months to <18 Years of Age With Moderate-to-Severe Atopic Dermatitis

for Atopic Dermatitis

21 locations incl. Birmingham

Sponsor: Eli Lilly and Company

Sex: All·Age: 6 Months - 18

Code: NCT05735483·Phase 3·Enrolling By Invitation

Investigating Novel Smoking Cessation Primary Care Interventions in Rural Environments

for Smoking Cessation

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05764759·Recruiting

Apply to this trial

Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein

for Alpha1-Antitrypsin Deficiency

37 locations incl. Birmingham

Sponsor: Takeda

Sex: All·Age: 18 - 75

Code: NCT05677971·Phase 3·Recruiting

Apply to this trial

Testing the Use of Ado-Trastuzumab Emtansine Compared to the Usual Treatment (Chemotherapy With Docetaxel Plus Trastuzumab) or Trastuzumab Deruxtecan for Recurrent, Metastatic, or Unresectable HER2-Expressing Salivary Gland Cancers

for Metastatic Salivary Gland Carcinoma

150 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05408845·Phase 2·Recruiting

Apply to this trial

A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma

for High Grade Osteosarcoma

Drug: Cabozantinib

177 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 40

Code: NCT05691478·Phase 2, Phase 3·Recruiting

Apply to this trial

A Study of Baricitinib (LY3009104) in Children From 6 Years to Less Than 18 Years of Age With Alopecia Areata

for Areata Alopecia

Drug: Baricitinib

44 locations incl. Birmingham

Sponsor: Eli Lilly and Company

Sex: All·Age: 6 - 17

Code: NCT05723198·Phase 3·Recruiting

Apply to this trial

A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss

for Childhood Medulloblastoma

101 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 4 - 21

Code: NCT05382338·Phase 3·Recruiting

Apply to this trial

Safety Study of Tenapanor for the Treatment of Pediatric Patients (6 to Less Than 18 Years Old) With IBS-C

for Irritable Bowel Syndrome With Constipation (IBS-C)

Drug: Tenapanor

27 locations incl. Foley

Sponsor: Ardelyx

Sex: All·Age: 6 - 18

Code: NCT05905926·Phase 3·Enrolling By Invitation

3D-Printed Versus Laboratory-Fabricated Hyrax Expanders

for Maxillary Expansion

2 locations incl. Pittsburgh

Sponsor: Ildeu Andrade Jr.

Sex: All·Age: 8 - 13·Accepts healthy volunteers

Code: NCT05743127·Recruiting

Apply to this trial

Building a Renewed ImaGe After Head & Neck Cancer Treatment (BRIGHT) Multi-Site RCT

for Head and Neck Cancer

5 locations incl. Detroit

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT05442957·Recruiting

Apply to this trial

A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures

for Primary Generalized Tonic-Clonic Seizures

Drug: XEN1101

59 locations incl. Mobile

Sponsor: Xenon Pharmaceuticals Inc.

Sex: All·Age: 12+

Code: NCT05667142·Phase 3·Recruiting

Apply to this trial

PUSH-IT Continuing Enteral Feeds for Tracheostomy

for Tracheostomy Complication

6 locations incl. Danbury

Sponsor: State University of New York at Buffalo

Sex: All·Age: 18+

Code: NCT05906472·Recruiting

Apply to this trial

Pilot/Pivotal Study of DBS+Rehab After Stroke

for Stroke

10 locations incl. Phoenix

Sponsor: Enspire DBS Therapy, Inc.

Sex: All·Age: 21+

Code: NCT05701280·Recruiting

Apply to this trial

Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial

for Metastatic Renal Cell Carcinoma

313 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05327686·Phase 2·Recruiting

Apply to this trial

mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma

for Advanced Esophageal Adenocarcinoma

Drug: Nivolumab

785 locations incl. Birmingham

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT05677490·Phase 3·Recruiting

Apply to this trial

The Impact of MeMed BV® on Management of Patients With Suspected Lower Respiratory Tract Infections (LRTI) in the Emergency Department (ED) and Urgent Care Center (UCC) ("JUPITER" TRIAL)

for Lower Respiratory Tract Infection

8 locations incl. Jacksonville

Sponsor: MeMed Diagnostics Ltd.

Sex: All·Age: 18 - 99

Code: NCT05762302·Recruiting

Apply to this trial

Non-interventional Study of Seroprevalence of Pre-existing Antibodies Against Adenovirus-associated Virus Vector (AAV9) and the Progression of Disease in Patients With Plakophilin 2 (PKP2)-Associated Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)

for Arrhythmogenic Right Ventricular Cardiomyopathy

8 locations incl. San Francisco

Sponsor: Tenaya Therapeutics

Sex: All·Age: 14 - 65

Code: NCT06311708·Recruiting

Apply to this trial

A Real World Study of eCoin for Urgency Urinary Incontinence: Post Approval Evaluation (RECIPE)

for Overactive Bladder

22 locations incl. Homewood

Sponsor: Valencia Technologies Corporation

Sex: All·Age: 18+

Code: NCT05685433·Recruiting

Apply to this trial

CARS: Cannabis and Alcohol Reduction Study

for Cannabis Use

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 13 - 17

Code: NCT05486234·Recruiting

Apply to this trial

Surveillance vs. Endoscopic Therapy for Barrett's Esophagus With Low-grade Dysplasia

for Barretts Esophagus With Dysplasia

23 locations incl. Los Angeles

Sponsor: University of Colorado, Denver

Sex: All·Age: 18 - 89

Code: NCT05753748·Recruiting

Apply to this trial

FORAGER-1: A Study of LOXO-435 (LY3866288) in Participants With Cancer With a Change in a Gene Called FGFR3

for Urinary Bladder Neoplasms

41 locations incl. Tucson

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT05614739·Phase 1·Recruiting

Apply to this trial

Alleviant ALLAY-HF Study

for Heart Failure

53 locations incl. Birmingham

Sponsor: Alleviant Medical, Inc.

Sex: All·Age: 40+

Code: NCT05685303·Enrolling By Invitation

Study of Dapansutrile Tablets in Subjects With an Acute Gout Flare

for Acute Gout Flare

25 locations incl. Birmingham

Sponsor: Olatec Therapeutics LLC

Sex: All·Age: 18+

Code: NCT05658575·Phase 2, Phase 3·Recruiting

Apply to this trial

DEFIANCE: RCT of ClotTriever System Versus Anticoagulation In Deep Vein Thrombosis

for Venous Thromboembolism

48 locations incl. Scottsdale

Sponsor: Inari Medical

Sex: All·Age: 18+

Code: NCT05701917·Recruiting

Apply to this trial

Endurant Stent Graft System vs Excluder Endoprothesis: ADVANCE Trial

for Abdominal Aortic Aneurysm

32 locations incl. Loma Linda

Sponsor: Medtronic Cardiovascular

Sex: All·Age: 20+

Code: NCT05378347·Recruiting

Apply to this trial

Improving the Collaborative Health of Minority COVID-19 Survivor and Carepartner Dyads

for SARS- CoV-2

1 location in Columbia

Sponsor: University of South Carolina

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05370014·Recruiting

Apply to this trial

A Biospecimen Collection Study to Identify the Targets of Disease-Reactive T Cells in Patients With Autoimmune Disease

for Autoimmune Diseases

12 locations incl. Orange

Sponsor: TScan Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06587828·Recruiting

Apply to this trial

Study of ONCOFID-P-B (PACLITAXEL-HYALURONIC ACID)

for Bladder Carcinoma in Situ (CIS)

6 locations incl. Gilbert

Sponsor: Fidia Farmaceutici s.p.a.

Sex: All·Age: 18+

Code: NCT05024773·Phase 3·Recruiting

Apply to this trial

Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)

for Atrial Fibrillation (AF)

Drug: Abelacimab

150 locations incl. Birmingham

Sponsor: Anthos Therapeutics, Inc.

Sex: All·Age: 65+

Code: NCT05712200·Phase 3·Recruiting

Apply to this trial

A Study to Evaluate Efficacy, Safety, and PK of XEMBIFY®+Standard Medical Treatment (SMT) Compared to Placebo+SMT to Prevent Infections in Participants With HGG and Recurrent or Severe Infections Associated With B-cell Chronic Lymphocytic Leukemia, Multiple Myeloma, and Non-Hodgkin Lymphoma

for Hypogammaglobulinemia

7 locations incl. Huntington Park

Sponsor: Grifols Therapeutics LLC

Sex: All·Age: 18+

Code: NCT05645107·Phase 3·Recruiting

Apply to this trial

Tebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)

for Advanced Melanoma

Drug: Tebentafusp

25 locations incl. Phoenix

Sponsor: Immunocore Ltd

Sex: All·Age: 18+

Code: NCT05549297·Phase 3·Recruiting

Apply to this trial

Multi-Center Molecular Diagnosis and Host Response of Respiratory Viral Infections in Pediatric Transplant Recipients

for Hematopoietic Cell Transplant

27 locations incl. Birmingham

Sponsor: Arkansas Children's Hospital Research Institute

Sex: All·Age: Up to 18

Code: NCT05550298·Recruiting

Apply to this trial

Efficacy and Safety of Tozorakimab in Patients Hospitalised for Viral Lung Infection Requiring Supplemental Oxygen

for Viral Lung Infection and Acute Respiratory Failure

68 locations incl. Mobile

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT05624450·Phase 3·Recruiting

Apply to this trial

Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)

for Triple Negative Breast Cancer

184 locations incl. Birmingham

Sponsor: Gilead Sciences

Sex: All·Age: 18+

Code: NCT05633654·Phase 3·Recruiting

Apply to this trial

Fracture Recovery for Returning to Duty (Teriparatide STRONG)

for Stress Fracture of Tibia or Fibula

1 location in Columbia

Sponsor: University of South Carolina

Sex: All·Age: All ages

Code: NCT04589819·Phase 4·Enrolling By Invitation

An Extension Study to Assess Long-Term Safety of Eplontersen in Adults With Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR-CM)

for Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR CM)

46 locations incl. Scottsdale

Sponsor: Ionis Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT05667493·Phase 3·Enrolling By Invitation

Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

for Endometrial Carcinoma

403 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT05256225·Phase 3·Recruiting

Apply to this trial

Masupirdine for the Treatment of Agitation in Dementia of the Alzheimer's Type

for Agitation

27 locations incl. Anaheim

Sponsor: Suven Life Sciences Limited

Sex: All·Age: 50 - 90

Code: NCT05397639·Phase 3·Recruiting

Apply to this trial

A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma

for Multiple Myeloma

Drug: Daratumumab

67 locations incl. Gilbert

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT05552222·Phase 3·Recruiting

Apply to this trial