Breast oncology Clinical Trials in Seattle, WA
As of July 2026, 39 paid clinical trials are recruiting for Breast oncology in Seattle, Washington. Breast oncology research tests new hormone therapies, HER2-targeted agents, PARP inhibitors, antibody-drug conjugates, and immunotherapy combinations across early-stage and metastatic disease. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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39 clinical trials for Breast oncology
·Clear filters·↓ Download CSVA Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment.
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer
A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)
A Study of Disitamab Vedotin in Adults With HER2 Expressing Advanced Breast Cancer
A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer
Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)
Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread
A Study of Emiltatug Ledadotin (Emi-Le) in Participants With Solid Tumors
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
A Phase 1/1b Study of IAM1363 in HER2 Cancers
MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
Phase 1/2 Study of ETX-636 in Participants With Advanced Solid Tumors
Phase 3 Study of Gedatolisib as First-Line Treatment for Patients With HR-Positive, HER2-Negative Advanced Breast Cancer (VIKTORIA-2)
A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors
A Study to Evaluate the Efficacy and Safety of Inavolisib in Combination With Phesgo Versus Placebo in Combination With Phesgo in Participants With PIK3CA-Mutated HER2-Positive Locally Advanced or Metastatic Breast Cancer
Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors
Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers
A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies
A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation
Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors
A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression
An Investigational Study of BG-75202 Alone and in Combination With Other Therapeutic Agents in Adults With Advanced Solid Tumors
BGB-21447 (Bcl-2 Inhibitor) Combinations for Adults With Hormone-Receptor Positive (HR+)/Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Metastatic Breast Cancer
A Study Evaluating the Safety, Pharmacokinetics and Early Efficacy of AVA6000 in Solid Tumours
A Registry Study of Breast Microseed Treatment
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Survivors
Axillary Radiotherapy or Axillary Lymph Node Dissection in Patients With Clinically Node- Positive Breast Cancer Undergoing Upfront Tailored Axillary Surgery
Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics
Hippocampal Avoidance in Craniospinal Irradiation for the Treatment of Leptomeningeal Metastases From Breast Cancer or Non-small Cell Lung Cancer
[18F]FTT Positron Emission Tomography for the Measurement of PARP Tumor Expression in Patients With Metastatic Breast Cancer
Avelumab or Hydroxychloroquine With or Without Palbociclib to Eliminate Dormant Breast Cancer
Quantitative MRI Assessment of Breast Cancer Therapy Response
Neoadjuvant INBRX-106 in Combination With Pembrolizumab for Stage II/III TNBC Patients
About research studies in Seattle
Seattle has approximately 1,297 recruiting research studies across a wide range of therapeutic areas. Washington hosts Fred Hutchinson Cancer Center, UW Medicine, and Seattle Children's — widely recognized for leadership in bone marrow transplantation, immunotherapy, and infectious disease research.
Top Research Study Locations in Seattle
Researchers run research studies in Seattle, WA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Seattle Children's Hospital | Diffuse Intrinsic Pontine Glioma, Cystic Fibrosis, High Grade Glioma | 192 |
| University of Washington | Amyotrophic Lateral Sclerosis, Multiple Myeloma, Spinal Cord Injuries | 186 |
| Fred Hutchinson Cancer Center | Breast Cancer, Colorectal Cancer, Acute Myeloid Leukemia | 142 |
| Fred Hutch/University of Washington Cancer Consortium | Acute Myeloid Leukemia, Hematopoietic and Lymphatic System Neoplasm, Mixed Phenotype Acute Leukemia | 104 |
| Swedish Medical Center-First Hill | Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, Malignant Solid Neoplasm | 66 |
| University of Washington Medical Center | Cystic Fibrosis, Heart Transplant, Tricuspid Regurgitation | 50 |
| Swedish Medical Center | ARDS, ARDS (Acute Respiratory Distress Syndrome), Acute Respiratory Distress Syndrome | 41 |
| University of Washington Medical Center - Montlake | Prostate Adenocarcinoma, Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8 | 38 |
| Swedish Cancer Institute | Breast Cancer, Endometrial Cancer, Breast Neoplasms | 37 |
| Fred Hutchinson Cancer Research Center | Advanced Solid Tumor, Chronic Lymphocytic Leukemia, Chronic Graft-versus-host-disease | 36 |
| Swedish Medical Center-Ballard Campus | Malignant Solid Neoplasm, Breast Cancer, Ovarian Carcinoma | 33 |
| Swedish Medical Center-Cherry Hill | Malignant Solid Neoplasm, Breast Cancer, Ovarian Carcinoma | 32 |
| Virginia Mason Medical Center | Breast Cancer, Hearing Loss, Unilateral, Pain | 29 |
| Harborview Medical Center | Ischemic Stroke, Spinal Cord Injuries, Abdominal Aortic Aneurysms | 20 |
| VA Puget Sound Health Care System Seattle Division, Seattle, WA | Lower Extremity Amputation, Obesity, Adult Growth Hormone Deficiency | 20 |
| Seattle Children's | Suicidal Ideation, Acute Kidney Injury, Becker Muscular Dystrophy | 18 |
| FHCC at Northwest Hospital | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIB Breast Cancer AJCC v8 | 14 |
| VA Puget Sound Health Care System | Parkinson's Disease, Amputation, Barrett's Esophagus | 13 |
| Fred Hutch Cancer Center | Colon Cancer, Colorectal Cancer, Advanced Adenocarcinoma | 12 |
| GSK Investigational Site | HIV Infections, Non-alcoholic Fatty Liver Disease, Gastrointestinal Neoplasms | 10 |
| Seattle Children's Research Institute | ADA SCID, Adolescent Behavior, Brain Concussion | 8 |
| Benaroya Research Institute | Acute Pancreatitis, Type 1 Diabetes Mellitus, Diabetes Mellitus, Type 1 | 7 |
| Seattle Cancer Care Alliance | Acute Myeloid Leukemia, Breast Cancer, Chronic Myelomonocytic Leukemia | 7 |
| University of Washington - Harborview Medical Center | Aneurysm, Intracranial, Brain Aneurysm, CPAP | 7 |
| Seattle Clinical Research Center | Obesity, Overweight, Acute Migraine | 6 |
Active & Upcoming Studies in Seattle (2026)
Recruiting trials in Seattle grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (496 active studies)
- ²¹¹At-OKT10-B10 and Fludarabine Alone or in Combination With Cyclophosphamide and Low-Dose TBI Before Donor Stem Cell Transplant for the Treatment of Newly Diagnosed, Recurrent, or Refractory High-Risk Multiple Myeloma · Phase 1 · Fred Hutchinson Cancer Center
- Enfortumab Vedotin, Pembrolizumab and Quemliclustat for the Treatment of Unresectable Locally Advanced and Metastatic Urothelial Cancer · Phase 1, Phase 2 · Fred Hutchinson Cancer Center
Neurology & pain (69 active studies)
- Morphine or Ketamine for Analgesia · Phase 3 · Columbia University
- My MS Toolkit: An Internet-Based Depression Self-Management Program for Adults Living With Multiple Sclerosis · University of Washington
Diabetes & metabolic (58 active studies)
- A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide · Phase 3 · Novo Nordisk A/S
- Inherited and Environmental Risks Acting on Body Weight · University of Washington
Cardiovascular (48 active studies)
- Tiprelestat Versus Placebo When Added to Standard of Care for the Treatment of Pulmonary Arterial Hypertension (PAH) · Phase 2 · Stanford University
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
Pediatric (29 active studies)
- Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG). · Phase 2 · BrainChild Bio, Inc
- Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion · EARLY_Phase 1 · Nationwide Children's Hospital
Mental health & behavior (27 active studies)
- VOCALE LBD: Online Peer Support for Caregivers of People With Lewy Body Dementia · University of Washington
- A Smartphone Application (QuitBot) for the Improvement of Smoking Cessation Among American Indians and Alaska Natives, NAITIVE Trial · Fred Hutchinson Cancer Center
HIV / STI (18 active studies)
- Optimizing Medications and Lung Health in People With HIV Through Pharmacist-led Proactive E-Consults · Seattle Institute for Biomedical and Clinical Research
- A Trial to Evaluate the Safety and Tolerability of DV700P-RNA and DV701B1.1-RNA Immunization in Combination With Antiretroviral Analytical Treatment Interruption (ATI) in People Living With HIV for Elicitation of V3-glycan Antibodies · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
Vaccines (11 active studies)
- A Study of Investigational RSV/hMPV Combination and Investigational hMPV Vaccines in Younger and Older Adults · Phase 1, Phase 2 · GlaxoSmithKline
- A Study on the Safety and Immune Response of Investigational mRNA Seasonal Flu/COVID-19 Combination Vaccine in Adults · Phase 1 · GlaxoSmithKline
Eye & vision (2 active studies)
- Disulfiram for Treatment of Retinal Degeneration · Phase 1, Phase 2 · University of Washington
- The Myelin Disorders Biorepository Project · Children's Hospital of Philadelphia
Common conditions studied in Seattle
- Acute Myeloid Leukemia (34 active studies). Leukemia trials evaluate targeted inhibitors, CAR-T cell therapies, and novel combinations for acute and chronic forms of the disease.
- Breast Cancer (22 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Colorectal Cancer (19 active studies). Colorectal cancer trials explore novel chemotherapy combinations, targeted agents, and immunotherapy for microsatellite-instability-high tumors.
- Ovarian Cancer (17 active studies). Ovarian cancer research examines PARP inhibitors, maintenance therapies, and antibody-drug conjugates for recurrent and platinum-resistant disease.
- Multiple Myeloma (15 active studies). Recruiting Multiple Myeloma studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Cancer (14 active studies). Recruiting Cancer studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
Leading research sponsors in Seattle
- University of Washington
- Fred Hutchinson Cancer Center
- National Cancer Institute (NCI)
- Seattle Children's Hospital
- Children's Oncology Group
Local regulations and guidelines
Clinical trials in Washington are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Studies in Washington must also comply with the My Health My Data Act, which adds consumer-health-data protections on top of federal HIPAA requirements.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Seattle. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Seattle
Hipa.ai aggregates every recruiting study in Seattle from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Seattle?
There are approximately 1,297 recruiting clinical trials in Seattle, Washington listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Seattle pay participants?
Most recruiting trials in Seattle compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Seattle?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Seattle?
The most common conditions under active study in Seattle include Acute Myeloid Leukemia (34), Breast Cancer (22), Colorectal Cancer (19), Ovarian Cancer (17), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Seattle?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Seattle on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Seattle?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Seattle?
Recruiting research sites in Seattle include Seattle Children's Hospital, University of Washington, Fred Hutchinson Cancer Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Seattle right now?
The largest active categories in Seattle are Cancer & tumors (496), Neurology & pain (69), Diabetes & metabolic (58). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.