Avera Cancer Sequencing and Analytics Protocol (ASAP)
for Cancer
Sites in Sioux Falls, Yankton +4 more locations
Sponsor: Avera McKennan Hospital & University Health Center
Sex: All·Age: 18+
Code: NCT05142033·Recruiting·Listed Dec 2021
Oncology Clinical Trials in Sioux Falls, SD
As of August 2026, 88 paid clinical trials are recruiting for Oncology in Sioux Falls, South Dakota. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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88 clinical trials for Oncology
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A Study of Azenosertib (ZN-c3) Versus Investigator's Choice Chemotherapy in Subjects With Platinum-Resistant High-Grade Serous Ovarian, Primary Peritoneal, or Fallopian Tube Cancers Positive for Cyclin E1 Protein Expression
for Ovarian Cancer
Sites in Sioux Falls +11 more locations
Sponsor: K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc
Sex: Female·Age: 18+
Code: NCT07546500·Phase 3·Recruiting·Listed Apr 2026
Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2
for Gastric Cancer
Drug: Sonesitatug vedotin
Sites in Sioux Falls +71 more locations
Sponsor: AstraZeneca
Sex: All·Age: 18+
Code: NCT07431281·Phase 3·Recruiting·Listed Feb 2026
A Study of Rilvegostomig or Durvalumab Plus Chemotherapy for First-Line Treatment of Biliary Tract Cancer (ARTEMIDE-Biliary02)
for Biliary Tract Cancer
Drug: Rilvegostomig
Sites in Sioux Falls, Pierre +34 more locations
Sponsor: AstraZeneca
Sex: All·Age: 18+
Code: NCT07221253·Phase 3·Recruiting·Listed Oct 2025
DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer
for Endometrial Cancer
Drug: Rilvegostomig
Sites in Sioux Falls +47 more locations
Sponsor: AstraZeneca
Sex: Female·Age: 18+
Code: NCT06989112·Phase 3·Recruiting·Listed May 2025
Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)
for Endometrial Cancer
Sites in Sioux Falls +66 more locations
Sponsor: AstraZeneca
Sex: Female·Age: 18+
Code: NCT07044336·Phase 3·Recruiting·Listed Jun 2025
A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)
for Non-small Cell Lung Cancer
Drug: Rilvegostomig
Sites in Sioux Falls +64 more locations
Sponsor: AstraZeneca
Sex: All·Age: 18+
Code: NCT06692738·Phase 3·Recruiting·Listed Nov 2024
Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations
for Non-Small Cell Lung Cancer
Drug: Rilvegostomig
Sites in Sioux Falls +48 more locations
Sponsor: AstraZeneca
Sex: All·Age: 18+
Code: NCT06357533·Phase 3·Recruiting·Listed Apr 2024
Conditions in Oncology (Sioux Falls, SD)
Breast cancer· 14Non-small cell lung cancer (NSCLC)· 14Ovarian cancer· 11Solid tumor· 11Endometrial cancer· 8Cancer (any)· 5Colorectal cancer· 4Gastroesophageal junction cancer· 4Fallopian tube cancer· 4Acute myeloid leukemia (AML)· 4Non-Hodgkin lymphoma· 4Diffuse large B-cell lymphoma (DLBCL)· 4Melanoma· 4Metastatic breast cancer· 3Esophageal cancer· 3Chronic lymphocytic leukemia (CLL)· 3Hematologic malignancy· 3Head and neck cancer· 3Neuroblastoma· 3Triple-negative breast cancer· 2Pancreatic cancer· 2Prostate cancer· 2Kidney cancer· 2Acute lymphoblastic leukemia· 2Leukemia (other)· 2Myelodysplastic syndromes (MDS)· 2Hodgkin lymphoma· 2Mantle cell lymphoma· 2HER2-positive breast cancer· 1HER2-negative breast cancer· 1Lung cancer· 1Colon cancer· 1Rectal cancer· 1Gastric cancer· 1Biliary tract cancer· 1Gynecologic cancer· 1Multiple myeloma· 1Myeloproliferative neoplasm· 1Follicular lymphoma· 1Small lymphocytic lymphoma· 1Burkitt lymphoma· 1Sarcoma· 1Osteosarcoma· 1Ewing sarcoma· 1