Paid Clinical Trials in Springfield, IL

As of August 2026, 171 paid clinical trials are recruiting in Springfield, Illinois. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 24, 2026.

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168 clinical trials

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Study to Test OBI-3424 in Patients With T-Cell Acute Lymphoblastic Leukemia (T-ALL) or T-Cell Lymphoblastic Lymphoma (T-LBL)

for Recurrent T Acute Lymphoblastic Leukemia

Sites in Springfield, Chicago +112 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 12+

Code: NCT04315324·Phase 1, Phase 2·Recruiting·Listed Mar 2020

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Efficacy of Simbrinza and Rocklatan vs Cosopt and Latanoprost

for Open Angle Glaucoma

1 location in Springfield

Sponsor: Prairie Eye Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06883123·Phase 4·Recruiting·Listed Mar 2025

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A Phase 2b Clinical Trial of YN001 in Adults With Coronary Atherosclerosis

for Atherosclerosis

Sites in Springfield +11 more locations

Sponsor: Beijing Inno Medicine Co., Ltd.

Sex: All·Age: 18 - 80

Code: NCT07521007·Phase 2·Recruiting·Listed Apr 2026

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A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous ABBV-706 Versus Standard of Care in Adult Participants With Relapsed/Refractory Small Cell Lung Cancer

for Small Cell Lung Cancer

Sites in Springfield, Peoria +25 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07365241·Phase 3·Recruiting·Listed Jan 2026

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Study of MAR001 in Adults With Elevated Triglycerides and Remnant Cholesterol

for Hypertriglyceridemia

Sites in Springfield, Park Ridge +24 more locations

Sponsor: Marea Therapeutics

Sex: All·Age: 18 - 75

Code: NCT07028749·Phase 2·Recruiting·Listed Jun 2025

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Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

for Endometrial Carcinoma

Sites in Springfield, Decatur +327 more locations

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT05256225·Phase 3·Recruiting·Listed Feb 2022

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Evaluation of Sonelokimab in Patients With Active Psoriatic Arthritis and Anti-TNFα Inadequate Response

for Arthritis, Psoriatic

Sites in Springfield +35 more locations

Sponsor: MoonLake Immunotherapeutics AG

Sex: All·Age: 18+

Code: NCT06641089·Phase 3·Recruiting·Listed Oct 2024

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Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACS

for Acute Coronary Syndrome

Sites in Springfield, Chicago +146 more locations

Sponsor: DalCor Pharmaceuticals

Sex: All·Age: 45+

Code: NCT05918861·Phase 3·Recruiting·Listed Jun 2023

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