Clinical Trials at Washington University

As of August 2026, 122 paid clinical trials are recruiting at Washington University, located at 1225 SOUTH GRAND, 2L, DOOR 1, ST LOUIS, MO 63104, phone (314) 977-4440 in St Louis, Missouri. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 13, 2026.

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123 clinical trials at Washington University

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Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer

for Advanced Solid Tumor

Sites in St Louis +10 more locations

Sponsor: Aulos Bioscience, Inc.

Sex: All·Age: 18+

Code: NCT05267626·Phase 1, Phase 2·Recruiting·Listed Mar 2022

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A Study of LY4175408 in Participants With Advanced Cancer

for Carcinoma, Non-Small-Cell Lung

Drug: LY4175408

Sites in St Louis +14 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07046923·Phase 1·Recruiting·Listed Jul 2025

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SLV-154 Treatment of Advanced Cancers

for Advanced Cancer

Sites in St Louis +9 more locations

Sponsor: Solve Therapeutics

Sex: All·Age: 12+

Code: NCT06771219·Phase 1·Recruiting·Listed Jan 2025

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A Study of TYRA-300 in Children With Achondroplasia: BEACH301

for Achondroplasia

Sites in St Louis, Columbia +10 more locations

Sponsor: Tyra Biosciences, Inc

Sex: All·Age: 3 - 10

Code: NCT06842355·Phase 2·Recruiting·Listed Feb 2025

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The Pivotal Study of RapidPulseTM Aspiration System

for Acute Ischemic Stroke

Sites in St Louis +14 more locations

Sponsor: RapidPulse, Inc

Sex: All·Age: 18 - 80

Code: NCT06029491·Recruiting·Listed Sep 2023

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SPEARHEAD-3 Pediatric Study

for Synovial Sarcoma

Sites in St Louis +9 more locations

Sponsor: USWM CT, LLC

Sex: All·Age: 2 - 21

Code: NCT05642455·Phase 1, Phase 2·Recruiting·Listed Dec 2022

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A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

for Solid Tumor, Adult

Sites in St Louis +11 more locations

Sponsor: A2 Biotherapeutics Inc.

Sex: All·Age: 18+

Code: NCT06051695·Phase 1, Phase 2·Recruiting·Listed Sep 2023

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Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

for Solid Tumor, Adult

Sites in St Louis +12 more locations

Sponsor: A2 Biotherapeutics Inc.

Sex: All·Age: 18+

Code: NCT04981119·Recruiting·Listed Jul 2021

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Study of mRNA-4359 Administered Alone and in Combination With Immune Checkpoint Blockade in Participants With Advanced Solid Tumors

for Advanced Solid Tumors

Sites in St Louis +13 more locations

Sponsor: ModernaTX, Inc.

Sex: All·Age: 12+

Code: NCT05533697·Phase 1, Phase 2·Recruiting·Listed Sep 2022

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Targeted Alpha-Particle Therapy for Advanced Somatostatin Receptor Type 2 (SSTR2) Positive Tumors

for Neuroendocrine Tumors Unresectable

Sites in St Louis +18 more locations

Sponsor: Perspective Therapeutics

Sex: All·Age: 18 - 90

Code: NCT05636618·Phase 1, Phase 2·Recruiting·Listed Dec 2022

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Acellular Dermal Matrix Investigation in Breast Reconstruction

for Breast Reconstruction

Sites in St Louis +12 more locations

Sponsor: RTI Surgical

Sex: Female·Age: 22+·Accepts healthy volunteers

Code: NCT06456554·Recruiting·Listed Jun 2024

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First in Human Study of TUB-030 in Patients With Advanced Solid Tumors

for Advanced Solid Tumors

Sites in St Louis +11 more locations

Sponsor: Tubulis GmbH

Sex: All·Age: 18+

Code: NCT06657222·Phase 1, Phase 2·Recruiting·Listed Oct 2024

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The FLOTILLA Study: Providing Continued Access to The Study Medicines Encorafenib and Binimetinib for Participants in Prior Clinical Trials

for Solid Tumors

Sites in St Louis +14 more locations

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT05203172·Phase 4·Recruiting·Listed Jan 2022

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A Study to Assess Adverse Events and Change in Disease Activity of Intravenously (IV) Infused ABBV-324 in Adult Participants With Hepatocellular Cancer (HCC) or Squamous-Cell Non-Small Cell Lung Cancer (LUSC)

for Hepatocellular Cancer

Sites in St Louis +9 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT06858813·Phase 1·Recruiting·Listed Mar 2025

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Pompe Pregnancy Sub-Registry

for Glycogen Storage Disease Type II (GSD-II)

Sites in St Louis +13 more locations

Sponsor: Genzyme, a Sanofi Company

Sex: Female·Age: All ages

Code: NCT00567073·Recruiting·Listed Dec 2007

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Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors

for Solid Tumor Malignancies

Sites in St Louis +12 more locations

Sponsor: Tasca Therapeutics

Sex: All·Age: 18+

Code: NCT07030257·Phase 1, Phase 2·Recruiting·Listed Jun 2025

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A Study of NVL-330 in Patients With Advanced or Metastatic HER2-altered NSCLC (HEROEX-1)

for Locally Advanced Solid Tumor

Sites in St Louis +16 more locations

Sponsor: Nuvalent Inc.

Sex: All·Age: 18+

Code: NCT06521554·Phase 1·Recruiting·Listed Jul 2024

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A Safety, Tolerability, and Biomarker Trial of VS-041 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)

for Heart

Sites in St Louis +20 more locations

Sponsor: Vasa Therapeutics

Sex: All·Age: 50+

Code: NCT07219511·Phase 1·Recruiting·Listed Oct 2025

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A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression

for Solid Tumor, Adult

Sites in St Louis +9 more locations

Sponsor: A2 Biotherapeutics Inc.

Sex: All·Age: 18+

Code: NCT06682793·Phase 1, Phase 2·Recruiting·Listed Nov 2024

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Cardiac RADIoablation Versus Repeat Catheter Ablation: a Pivotal Randomized Clinical Trial Evaluating Safety and Efficacy for Patients With High-risk Refractory Ventricular Tachycardia (RADIATE-VT)

for Tachycardia, Ventricular

Sites in St Louis, Columbia +9 more locations

Sponsor: Varian, a Siemens Healthineers Company

Sex: All·Age: 18+

Code: NCT05765175·Recruiting·Listed Mar 2023

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Study Evaluating the Efficacy of KITE-753 Versus Axicabtagene Ciloleucel in Participants With Relapsed or Refractory Large B-Cell Lymphoma After First-Line Therapy

for Relapsed or Refractory Large B-cell Lymphoma

Sites in St Louis +9 more locations

Sponsor: Kite, A Gilead Company

Sex: All·Age: 18+

Code: NCT07479797·Phase 3·Recruiting·Listed Mar 2026

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A Clinical Trial Investigating the Safety and Biological Activity of the Antibody BNT351 in Adults Living Without and With HIV

for HIV -1 Infection

Drug: BNT351

Sites in St Louis +3 more locations

Sponsor: BioNTech SE

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07392372·Phase 1·Recruiting·Listed Feb 2026

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Phase 2 Study of SAT-3247 in Pediatric Ambulatory Patients

for Duchenne Muscular Dystrophy

Sites in St Louis +6 more locations

Sponsor: Satellos Bioscience, Inc.

Sex: Male·Age: 7 - 9

Code: NCT07287189·Phase 2·Recruiting·Listed Dec 2025

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Study of ONC206 (JZP3507) in Advanced Pheochromocytoma and Paraganglioma

for Advanced Pheochromocytoma and Paraganglioma

Sites in St Louis +8 more locations

Sponsor: Jazz Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07282587·Phase 2·Recruiting·Listed Dec 2025

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Danon Disease Natural History Study

for Danon Disease

Sites in St Louis +8 more locations

Sponsor: Rocket Pharmaceuticals Inc.

Sex: All·Age: 8+

Code: NCT06214507·Recruiting·Listed Jan 2024

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A Study to Compare the Efficacy and Safety of TachoSil and Surgicel Original as an Adjunct to Control Mild to Moderate Soft Tissue Bleeding During Surgery

for Hemorrhage

Sites in St Louis +8 more locations

Sponsor: Corza Medical GmbH

Sex: All·Age: 1 Month+

Code: NCT06664775·Phase 3·Recruiting·Listed Oct 2024

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Evaluation of Neoadjuvant Xaluritamig in Localized Prostate Cancer

for Prostate Cancer

Sites in St Louis +6 more locations

Sponsor: Amgen

Sex: Male·Age: 18+

Code: NCT06613100·Phase 1·Recruiting·Listed Sep 2024

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EPIK-P4: A Phase II Single-arm Study to Assess the Efficacy, Safety and Pharmacokinetics of Alpelisib (BYL719) in Pediatric and Adult Patients With PIK3CA-related Overgrowth Spectrum (PROS)

for PIK3CA-related Overgrowth Spectrum (PROS)

Sites in St Louis +5 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 2 - 100

Code: NCT06997588·Phase 2·Recruiting·Listed May 2025

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Gene Correction in Autologous CD34+ Hematopoietic Stem Cells (HbS to HbA) to Treat Severe Sickle Cell Disease

for Sickle Cell Disease

Sites in St Louis +5 more locations

Sponsor: Kamau Therapeutics

Sex: All·Age: 12 - 50

Code: NCT04819841·Phase 1, Phase 2·Recruiting·Listed Mar 2021

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Study of Intravenously (IV) Infused Etentamig in Combination With an Oral Cereblon E3 Ligase Modulatory Drug (CELMoD) Agent Assessing Adverse Events and Change in Disease Activity in Adult Participants With Relapsed or Refractory Multiple Myeloma

for Multiple Myeloma

Drug: Etentamig

Sites in St Louis +6 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT06896916·Phase 1·Recruiting·Listed Mar 2025

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Clinical Evaluation of BCDx for Monitoring of Recurrence in Non-Muscle Invasive Bladder Cancer

for Bladder Cancer

Sites in St Louis +2 more locations

Sponsor: Early is Good Inc.

Sex: All·Age: 18+

Code: NCT05982561·Recruiting·Listed Aug 2023

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SLV-324 Treatment of Metastatic Solid Tumors

for Metastatic Solid Tumors

Sites in St Louis +6 more locations

Sponsor: Solve Therapeutics

Sex: All·Age: 18+

Code: NCT07108114·Phase 1·Recruiting·Listed Aug 2025

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A Study of KK2269 in Adult Participants With Solid Tumors

for Advanced Solid Tumor

Sites in St Louis +6 more locations

Sponsor: Kyowa Kirin Co., Ltd.

Sex: All·Age: 18+

Code: NCT06266299·Phase 1·Recruiting·Listed Feb 2024

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JAB-2485 Activity in Adult Patients With Advanced Solid Tumors

for Solid Tumors

Sites in St Louis +3 more locations

Sponsor: Jacobio Pharmaceuticals Co., Ltd.

Sex: All·Age: 18+

Code: NCT05490472·Phase 1, Phase 2·Recruiting·Listed Aug 2022

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JAB-23E73 in Adult Participants With Advanced Solid Tumors With KRAS Alteration

for Advanced Solid Tumors

Sites in St Louis +3 more locations

Sponsor: Jacobio Pharmaceuticals Co., Ltd.

Sex: All·Age: 18+

Code: NCT06973564·Phase 1, Phase 2·Recruiting·Listed May 2025

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A Safety and Efficacy Study Evaluating CTX112 in Subjects With Relapsed or Refractory B-Cell Malignancies

for B-cell Lymphoma

Sites in St Louis +3 more locations

Sponsor: CRISPR Therapeutics AG

Sex: All·Age: 18+

Code: NCT05643742·Phase 1, Phase 2·Recruiting·Listed Dec 2022

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Study of Enhanced Programming Stimulation with the Enterra® Therapy System

for Gastroparesis

Sites in St Louis +5 more locations

Sponsor: Enterra Medical, Inc.

Sex: All·Age: 18 - 70

Code: NCT06560307·Recruiting·Listed Aug 2024

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PREcision MEDicine In Achalasia (PREMEDIA) - Cohort

for Type III Achalasia

Sites in St Louis +14 more locations

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT07293689·Recruiting·Listed Dec 2025

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PREcision MEDicine In Achalasia (PREMEDIA)

for Type I Achalasia

Sites in St Louis +14 more locations

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT07293650·Phase 3·Recruiting·Listed Dec 2025

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Idiopathic Pulmonary Fibrosis and Interstitial Lung Disease Prospective Outcomes Registry

for Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease

Sites in St Louis +38 more locations

Sponsor: Duke University

Sex: All·Age: 21+

Code: NCT01915511·Recruiting·Listed Aug 2013

Apply to this trial