Clinical Trials at Washington University School of Medicine

As of August 2026, 434 paid clinical trials are recruiting at Washington University School of Medicine, located at Washington University School of Medicine, 1 Children's Pl, St. Louis, MO 63110, phone (314) 454-6215 in St Louis, Missouri. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 13, 2026.

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436 clinical trials at Washington University School of Medicine

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IDOV-Immune for Advanced Solid Tumors

for Colorectal Cancer

Sites in St Louis +2 more locations

Sponsor: ViroMissile, Inc.

Sex: All·Age: 18+

Code: NCT06910657·Phase 1·Recruiting·Listed Apr 2025

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A Feasibility Study to Evaluate the Safety of the TheraSphere Glioblastoma (GBM) Device in Patients With Recurrent GBM

for Glioblastoma Multiforme

Sites in St Louis +6 more locations

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT05303467·Phase 1·Recruiting·Listed Mar 2022

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A Study to Test Different Doses of Obrixtamig in Patients With Small Cell Lung Cancer and Other Neuroendocrine Tumours That Are Positive for DLL3

for Small Cell Lung Carcinoma and Other Neuroendocrine Neoplasms Expressing DLL3

Drug: Obrixtamig

Sites in St Louis +2 more locations

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT04429087·Phase 1·Recruiting·Listed Jun 2020

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A Study of Pasritamig (JNJ-78278343) in Combination With Other Agents for Metastatic Prostate Cancer

for Metastatic Hormone-sensitive Prostate Cancer

Drug: Pasritamig

Sites in St Louis +6 more locations

Sponsor: Janssen Research & Development, LLC

Sex: Male·Age: 18+

Code: NCT05818683·Phase 1·Recruiting·Listed Apr 2023

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A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease

for SLE (Systemic Lupus)

Sites in St Louis +6 more locations

Sponsor: CRISPR Therapeutics

Sex: All·Age: 18 - 70

Code: NCT06925542·Phase 1·Recruiting·Listed Apr 2025

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A Study to Investigate the Safety of Novel Dose Ramp-up Schedule(s) When Initiating Sonrotoclax in Participants Treated for Blood Cancers.

for Chronic Lymphocytic Leukemia

Drug: Sonrotoclax

Sites in St Louis +5 more locations

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT06697184·Phase 1, Phase 2·Recruiting·Listed Nov 2024

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A Study of Patients With Fabry Disease (US Specific)

for Fabry Disease

Sites in St Louis +7 more locations

Sponsor: Amicus Therapeutics

Sex: All·Age: 18+

Code: NCT06906367·Recruiting·Listed Apr 2025

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A Study of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SR604 in Two Participants Groups (Part A: Healthy Participants, and Part B: Participants With Hemophilia A or Hemophilia B or Factor VII Deficiency)

for Healthy Participants

Sites in St Louis +7 more locations

Sponsor: Equilibra Bioscience LLC

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT06349473·Phase 1·Recruiting·Listed Apr 2024

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Study of EXE-346 Live Biotherapeutic to Reduce High Bowel Movement Frequency in Subjects With an IPAA (PROF)

for Ileal Pouch

Sites in St Louis +7 more locations

Sponsor: Exegi Pharma, LLC

Sex: All·Age: 18+

Code: NCT05938465·Phase 1, Phase 2·Recruiting·Listed Jul 2023

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NG-350A Plus Chemoradiotherapy for Locally Advanced Rectal Cancer

for Locally Advanced Rectal Cancer (LARC)

Sites in St Louis +3 more locations

Sponsor: Akamis Bio

Sex: All·Age: 18+

Code: NCT06459869·Phase 1·Recruiting·Listed Jun 2024

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A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

for Cancer

Sites in St Louis +5 more locations

Sponsor: Angiex, Inc.

Sex: All·Age: 18+

Code: NCT06440005·Phase 1·Recruiting·Listed Jun 2024

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Endovascular Repair With Fenestrated TREO Stent-Graft System in AAA

for Abdominal Aortic Aneurysms (AAA)

Sites in St Louis +4 more locations

Sponsor: Bolton Medical

Sex: All·Age: 18+

Code: NCT07026877·Recruiting·Listed Jun 2025

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A Study of TLN-254 in Participants With Relapsed or Refractory T-cell Lymphoma

for Lymphoma

Sites in St Louis +3 more locations

Sponsor: Treeline Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT06733441·Phase 1·Recruiting·Listed Dec 2024

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A Single-arm, Pivotal Study to Evaluate Acute Device and Technical Success of the CGuard Prime Carotid Stent System When Used in Conjunction to the ENROUTE Transcarotid Neuroprotection System in Patients Undergoing Carotid Artery Stenting Via the Transcarotid Artery Revascularization Approach

for Carotid Artery Diseases

Sites in St Louis +7 more locations

Sponsor: InspireMD

Sex: All·Age: 18 - 79

Code: NCT06653387·Recruiting·Listed Oct 2024

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Study of Safety and Efficacy of RGT-61159 in Adults With Relapsed/Refractory Adenoid Cystic Carcinoma (ACC) or Colorectal Carcinoma (CRC)

for Adenoid Cystic Carcinoma

Sites in St Louis +7 more locations

Sponsor: Rgenta Therapeutics Inc

Sex: All·Age: 18+

Code: NCT06462183·Phase 1·Recruiting·Listed Jun 2024

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A Pragmatic Clinical Trial of the WE BEAT Well-Being Education Program in Adolescent Congenital Heart Disease: WE BEAT CHD Study

for Patient-Reported Outcome Measures (PROMs)

Sites in St Louis +13 more locations

Sponsor: Carelon Research

Sex: All·Age: 12 - 17

Code: NCT07525843·Recruiting·Listed Apr 2026

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Feasibility of HPV Self-Collection Kits for Cervical Cancer Screening

for Cervical Cancer

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: Female·Age: 25+·Accepts healthy volunteers

Code: NCT07453459·Recruiting·Listed Mar 2026

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Testing the Addition of Anti-Cancer Drug Sonrotoclax, to the Standard Treatment Zanubrutinib, for Previously Untreated CLL/SLL

for Chronic Lymphocytic Leukemia

Drug: Sonrotoclax

Sites in St Louis, Creve Coeur +179 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 65+

Code: NCT07321652·Phase 3·Recruiting·Listed Jan 2026

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Inflammation in Primary and Secondary Malignancies of the Central Nervous System Using [C-11]-CS1P1

for Central Nervous System Cancer

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT07462507·Phase 2·Recruiting·Listed Mar 2026

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Remote Ischemic Conditioning for PwSCI

for Spinal Cord Injuries

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT07488793·Recruiting·Listed Mar 2026

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Safety and Efficacy of CTX-009 With or Without CTX-471 for Recurrent Glioblastoma

for Glioblastoma

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT07392957·Phase 1, Phase 2·Recruiting·Listed Feb 2026

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PET Imaging of MMP Activation in AAA: Clinical Component

for Abdominal Aortic Aneurysm

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07473102·EARLY_Phase 1·Recruiting·Listed Mar 2026

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First-Line Ipilimumab Plus Nivolumab and Nogapendekin Alfa Inbakicept (N-803) in Patients With Stage IV or Recurrent Non-Small Cell Lung Cancer

for Non-small Cell Lung Cancer Stage IV

Drug: Ipilimumab

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT07355205·Phase 1, Phase 2·Recruiting·Listed Jan 2026

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5-Fluorouracil Response and Optimization STudy (The FROST Trial)

for Squamous Cell Carcinoma of Head and Neck

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT07419464·Phase 2·Recruiting·Listed Feb 2026

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Study to Enable New Diagnostics for Pulmonary Microbes in People With CF

for Cystic Fibrosis (CF)

Sites in St Louis +8 more locations

Sponsor: Chris Goss

Sex: All·Age: 16+

Code: NCT07312734·Recruiting·Listed Dec 2025

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Therapeutic RSK1 Targeting in Myelofibrosis

for Myelofibrosis

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT07379125·Phase 1·Recruiting·Listed Jan 2026

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Patient Position Monitoring System for Beam Gated Radiation Therapy of Malignancies of the Chest and Upper Abdomen

for Radiotherapy

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT07373496·Recruiting·Listed Jan 2026

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CARE Tool Study Aim 3

for Gynecologic Cancer

Sites in St Louis, Rolla +1 more location

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT07296887·Recruiting·Listed Dec 2025

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Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

for Breast Cancer

Sites in St Louis, Creve Coeur +1098 more locations

Sponsor: NRG Oncology

Sex: Female·Age: 18 - 60

Code: NCT05879926·Phase 3·Recruiting·Listed May 2023

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Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

for Lung Non-Small Cell Carcinoma

Sites in St Louis, Creve Coeur +633 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04267848·Phase 3·Recruiting·Listed Feb 2020

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Healthy Behaviors for Insomnia Prevention in People With HIV and Ongoing Pain

for Chronic Pain

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 25 - 65

Code: NCT07270406·Recruiting·Listed Dec 2025

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Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease

for Stage III Colon Cancer

Sites in St Louis, Creve Coeur +913 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05174169·Phase 2, Phase 3·Recruiting·Listed Dec 2021

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Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab

for Anatomic Stage II Breast Cancer AJCC v8

Sites in St Louis, Creve Coeur +777 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT05812807·Phase 3·Recruiting·Listed Apr 2023

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Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas

for Intracranial Meningioma

Sites in St Louis, Ballwin +444 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT02523014·Phase 2·Recruiting·Listed Aug 2015

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ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab

for Anatomic Stage I Breast Cancer AJCC v8

Sites in St Louis, Creve Coeur +591 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT06876714·Phase 3·Recruiting·Listed Mar 2025

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Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck Cancer

for Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8

Sites in St Louis, Creve Coeur +99 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07195734·Phase 2·Recruiting·Listed Sep 2025

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Health Information for Persons With Spinal Cord Injury

for Spinal Cord Injuries (SCI)

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT07386522·Recruiting·Listed Feb 2026

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Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

for Chronic Lymphocytic Leukemia

Sites in St Louis, Chesterfield +295 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04269902·Phase 3·Recruiting·Listed Feb 2020

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Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer

for Fallopian Tube Endometrioid Adenocarcinoma

Drug: Bevacizumab

Sites in St Louis, Ballwin +653 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT06580314·Phase 3·Recruiting·Listed Aug 2024

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Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

for Bladder Adenocarcinoma

Drug: Cabozantinib

Sites in St Louis, Creve Coeur +221 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT03866382·Phase 2·Recruiting·Listed Mar 2019

Apply to this trial