Clinical Trials at Washington University in St. Louis

As of September 2026, 71 paid clinical trials are recruiting at Washington University in St. Louis, located at Siteman Care Cancer Center Washington University in St. Louis, 4500 Forest Park Ave, St. Louis, MO 63108, phone (314) 362-7509 in St Louis, Missouri. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 24, 2026.

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73 clinical trials at Washington University in St. Louis

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Evaluation of a Novel Technology to Support Tailored Health Behavior Counseling in Rural Primary Care Clinics

for Cardiovascular Diseases

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18 - 64

Code: NCT06397729·Recruiting·Listed May 2024

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Adapting and Testing a Novel Digital Health Tool (PREVENT) to Improve Health Behavior Counseling and Cardiovascular Health in Rural Primary Care Clinics

for Obesity

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18 - 64

Code: NCT06063564·Recruiting·Listed Oct 2023

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This Study Involves a Positron Emission Tomography (PET) Scan Using a New Investigational Radioactive Tracer, [18F]-FZTA, to Detect Inflammation in the Brain. The Tracer Will be Tested in Healthy Younger Adults and Individuals With Multiple Sclerosis.

for Multiple Sclerosis

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07115017·Recruiting·Listed Aug 2025

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TSC Biosample Repository and Natural History Database

for Tuberous Sclerosis

Sites in St Louis, Kansas City +21 more locations

Sponsor: National Tuberous Sclerosis Association

Sex: All·Age: All ages

Code: NCT05676099·Recruiting·Listed Jan 2023

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Pulmonary Embolism - Thrombus Removal With Catheter-Directed Therapy

for Pulmonary Embolism

Sites in St Louis +39 more locations

Sponsor: NYU Langone Health

Sex: All·Age: 18+

Code: NCT05591118·Phase 3·Recruiting·Listed Oct 2022

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Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women

for Heart Diseases

Sites in St Louis +40 more locations

Sponsor: Weill Medical College of Cornell University

Sex: Female·Age: 18+

Code: NCT04124120·Recruiting·Listed Oct 2019

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Investigations of Dementia in Parkinson Disease

for Parkinsons

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 50+·Accepts healthy volunteers

Code: NCT02763683·Recruiting·Listed May 2016

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Early Intervention to Promote Cardiovascular Health of Mothers and Children

for Cardiovascular Health

Sites in St Louis +8 more locations

Sponsor: JHSPH Center for Clinical Trials

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT06272045·Recruiting·Listed Feb 2024

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RESTORE: REducing Future fractureS and Improving ouTcOmes of fRagility fracturE

for Osteoporosis

Sites in St Louis, Columbia +21 more locations

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 50+

Code: NCT06455085·Recruiting·Listed Jun 2024

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Stroke Thrombectomy and Aneurysm Registry

for Stroke

Sites in St Louis +53 more locations

Sponsor: Medical University of South Carolina

Sex: All·Age: 1 - 120

Code: NCT04994756·Recruiting·Listed Aug 2021

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Study of Biodistribution, Metabolism, Excretion and Brain Uptake11C-M503

for Tauopathies

Sites in St Louis +2 more locations

Sponsor: University of Pennsylvania

Sex: All·Age: 40 - 85·Accepts healthy volunteers

Code: NCT06303921·EARLY_Phase 1·Recruiting·Listed Mar 2024

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Nerve Transfer to Improve Function in High Level Tetraplegia

for Cervical Spinal Cord Injury

Sites in St Louis +8 more locations

Sponsor: Washington University School of Medicine

Sex: All·Age: 18 - 80

Code: NCT06288763·Recruiting·Listed Mar 2024

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Black and African Americans Connections to Parkinson's Disease (BLAAC PD)

for Parkinson Disease

Sites in St Louis +10 more locations

Sponsor: Michael J. Fox Foundation for Parkinson's Research

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06719583·Recruiting·Listed Dec 2024

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Montalcino Aortic Consortium: Precision Medicine for Heritable Thoracic Aortic Disease

for Aortic Aneurysm

Sites in St Louis +13 more locations

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT04005976·Recruiting·Listed Jul 2019

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Prevention/Reduction of ASRs and PTSD to Sustain Civilian Performance With Sublingual Cyclobenzaprine HCl (TNX-102 SL)

for Acute Stress Reaction

Sites in St Louis +8 more locations

Sponsor: University of North Carolina, Chapel Hill

Sex: All·Age: 18 - 55

Code: NCT06636786·Phase 2·Recruiting·Listed Oct 2024

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CANF-Comb-II PET-MR in Atherosclerosis Multisite

for Carotid Atherosclerosis

Sites in St Louis +1 more location

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT05838547·Recruiting·Listed May 2023

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Optimal Ventilation for Cardiac Arrest

for Cardiac Arrest (CA)

Sites in St Louis +19 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 37 Weeks - 18

Code: NCT07114510·Recruiting·Listed Aug 2025

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Compass 3: A Novel Transition Program to Reduce Disability After Stroke

for Stroke

Sites in St Louis & Columbia

Sponsor: Washington University School of Medicine

Sex: All·Age: 55+

Code: NCT07069660·Recruiting·Listed Jul 2025

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Dissemination of the Donor Application: Utilizing Social Media to Identify Potential Live Organ Donors

for End Stage Renal Disease

Sites in St Louis +5 more locations

Sponsor: Johns Hopkins University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT03803423·Recruiting·Listed Jan 2019

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Rare and Atypical Diabetes Network

for Diabetes Mellitus

Sites in St Louis +12 more locations

Sponsor: University of South Florida

Sex: All·Age: All ages

Code: NCT05544266·Recruiting·Listed Sep 2022

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Multi-Site Trial of Navigation vs Treatment as Usual to Improve Initiation of Timely Adjuvant Therapy

for Head and Neck Cancer

Sites in St Louis +3 more locations

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT05793151·Recruiting·Listed Mar 2023

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Adapting, Implementing and Evaluating the Effectiveness of HARP for People With Disabilities

for Disabilities Physical

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 45 - 64

Code: NCT07033897·Recruiting·Listed Jun 2025

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Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort

for Huntington's Disease

Sites in St Louis +51 more locations

Sponsor: CHDI Foundation, Inc.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT01574053·Recruiting·Listed Apr 2012

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Clinical Utility of Residual Hearing in the Cochlear Implant Ear

for Hearing Loss, Sensorineural

Sites in St Louis +4 more locations

Sponsor: Ohio State University

Sex: All·Age: 18 - 79

Code: NCT04707885·Recruiting·Listed Jan 2021

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BXCL501 After Stress to Increase Recovery Success

for Acute Stress Reaction

Sites in St Louis +2 more locations

Sponsor: University of North Carolina, Chapel Hill

Sex: All·Age: 18 - 65

Code: NCT06943404·Phase 2·Recruiting·Listed Apr 2025

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Pulmonary Hypertension Association Registry

for Pulmonary Arterial Hypertension

Sites in St Louis +51 more locations

Sponsor: Pulmonary Hypertension Association, Inc.

Sex: All·Age: 0+

Code: NCT04071327·Recruiting·Listed Aug 2019

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A Trial Evaluating the Effect of NIO752 on Tau Synthesis Measured by a Process Known as SILK

for Alzheimer Disease

Drug: NIO752

1 location in St Louis

Sponsor: University College, London

Sex: All·Age: 21 - 80

Code: NCT06372821·Phase 1·Recruiting·Listed Apr 2024

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Domatinostat With Sirolimus for Relapsed, Refractory Sarcoma and Osteosarcoma

for Sarcoma

Sites in St Louis +3 more locations

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 12 - 40

Code: NCT07725380·Phase 1, Phase 2·Recruiting·Listed Jul 2026

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Cardiac Magnetic Resonance and Echocardiography Study With Acoramidis

for Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM)

Drug: Acoramidis

1 location in St Louis

Sponsor: Eidos Therapeutics, a BridgeBio company

Sex: All·Age: 18 - 80

Code: NCT07695701·Phase 4·Recruiting·Listed Jul 2026

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Eating Disorder Chatbot Optimization

for Eating Disorders

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT07218302·Phase 2·Recruiting·Listed Oct 2025

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Efficacy of a Multi-level School Intervention for LGBTQ Youth

for Depression

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 12 - 20·Accepts healthy volunteers

Code: NCT05541406·Recruiting·Listed Sep 2022

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