A Study of Disitamab Vedotin in Adults With HER2 Expressing Advanced Breast Cancer
for Breast Cancer
Sites in Trumbull, Fairfield +132 more locations
Sponsor: Pfizer
Sex: All·Age: 18+
Code: NCT06966453·Phase 1, Phase 2·Recruiting·Listed May 2025
Paid Clinical Trials in Trumbull, CT
As of August 2026, 62 paid clinical trials are recruiting in Trumbull, Connecticut. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Trumbull offers studies at sites including Smilow Cancer Hospital Care Center-Trumbull for conditions such as Stage IV Lung Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Breast Cancer, Extensive Stage Lung Small Cell Carcinoma. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Trumbull
Trials by drug in Trumbull
Filter results
Filter results
62 clinical trials
A Study of the Efficacy and Safety of Adjuvant Autogene Cevumeran Plus Atezolizumab and mFOLFIRINOX Versus mFOLFIRINOX Alone in Participants With Resected PDAC
for Adenocarcinoma, Pancreatic Ductal
Drug: Atezolizumab
Sites in Trumbull, New Haven +28 more locations
Sponsor: Genentech, Inc.
Sex: All·Age: 18+
Code: NCT05968326·Phase 2·Recruiting·Listed Aug 2023
A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors
for Advanced/Metastatic Solid Tumors
Sites in Trumbull, New Haven +19 more locations
Sponsor: Pfizer
Sex: All·Age: 18+
Code: NCT07090499·Phase 1·Recruiting·Listed Jul 2025
Phase 1 Study of PF-08046033 in Advanced Solid Tumors
for Non-Small-Cell Lung
Sites in Trumbull, New Haven +9 more locations
Sponsor: Pfizer
Sex: All·Age: 18+
Code: NCT07519655·Phase 1·Recruiting·Listed Apr 2026
Sustained Acoustic Medicine (SAM) for Symptomatic Treatment of Pain Related to Bone Fracture
for Bone Fracture
Sites in Trumbull +1 more location
Sponsor: ZetrOZ, Inc.
Sex: All·Age: 18 - 80·Accepts healthy volunteers
Code: NCT05883241·Phase 1·Recruiting·Listed May 2023
Testing Addition of an Anti-cancer Drug, Vorasidenib to Temozolomide, After Radiation for Advanced Brain Cancer
for Astrocytoma, IDH-Mutant, Grade 3
Drug: Vorasidenib
Sites in Trumbull, New Haven +95 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 12+
Code: NCT07215910·Phase 3·Recruiting·Listed Oct 2025
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
for Breast Cancer
Sites in Trumbull, Bridgeport +1098 more locations
Sponsor: NRG Oncology
Sex: Female·Age: 18 - 60
Code: NCT05879926·Phase 3·Recruiting·Listed May 2023
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
for Lung Non-Small Cell Carcinoma
Sites in Trumbull, Fairfield +632 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT04267848·Phase 3·Recruiting·Listed Feb 2020
Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
for Stage III Colon Cancer
Sites in Trumbull, Fairfield +913 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT05174169·Phase 2, Phase 3·Recruiting·Listed Dec 2021
Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab
for Anatomic Stage II Breast Cancer AJCC v8
Sites in Trumbull, Bridgeport +777 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT05812807·Phase 3·Recruiting·Listed Apr 2023
Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas
for Intracranial Meningioma
Sites in Trumbull, New Haven +444 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT02523014·Phase 2·Recruiting·Listed Aug 2015
ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab
for Anatomic Stage I Breast Cancer AJCC v8
Sites in Trumbull, Fairfield +591 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT06876714·Phase 3·Recruiting·Listed Mar 2025
Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial
for Advanced Hepatocellular Carcinoma
Sites in Trumbull, Fairfield +136 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT07166406·Phase 3·Recruiting·Listed Sep 2025
Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
for Fallopian Tube Endometrioid Adenocarcinoma
Drug: Bevacizumab
Sites in Trumbull, Fairfield +653 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT06580314·Phase 3·Recruiting·Listed Aug 2024
Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer
for Advanced Lung Non-Squamous Non-Small Cell Carcinoma
Drug: Bevacizumab
Sites in Trumbull, Fairfield +325 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT04181060·Phase 3·Recruiting·Listed Nov 2019
Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer
for Anatomic Stage II Breast Cancer AJCC v8
Drug: Durvalumab
Sites in Trumbull, Fairfield +532 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06058377·Phase 3·Recruiting·Listed Sep 2023
Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery
for Head and Neck Squamous Cell Carcinoma
Sites in Trumbull, New Haven +464 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: 18+
Code: NCT02734537·Phase 2·Recruiting·Listed Apr 2016
Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trial
for Extensive Stage Lung Small Cell Carcinoma
Drug: Atezolizumab
Sites in Trumbull, Fairfield +268 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT04402788·Phase 2, Phase 3·Recruiting·Listed May 2020
Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer
for Clear Cell Renal Cell Carcinoma
Sites in Trumbull, Bridgeport +406 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT06661720·Phase 3·Recruiting·Listed Oct 2024
Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study
for Muscle Invasive Bladder Urothelial Carcinoma
Sites in Trumbull, Bridgeport +445 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT05987241·Phase 2, Phase 3·Recruiting·Listed Aug 2023
Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer
for Locally Advanced Unresectable Pancreatic Ductal Adenocarcinoma
Sites in Trumbull, Fairfield +314 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT06958328·Phase 3·Recruiting·Listed May 2025
Study of Targeted Therapy vs. Chemotherapy in Patients With Thyroid Cancer
for Refractory Differentiated Thyroid Gland Carcinoma
Sites in Trumbull, Fairfield +284 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: 18+
Code: NCT06475989·Phase 3·Recruiting·Listed Jun 2024
Testing Continuous Versus Intermittent Treatment With the Study Drug Zanubrutinib for Older Patients With Previously Untreated Mantle Cell Lymphoma
for Mantle Cell Lymphoma
Sites in Trumbull, Fairfield +228 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 60+
Code: NCT05976763·Phase 3·Recruiting·Listed Aug 2023
Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial
for Advanced Esophageal Adenocarcinoma
Drug: Nivolumab
Sites in Trumbull, Fairfield +339 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06203600·Phase 2, Phase 3·Recruiting·Listed Jan 2024
A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab
for Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8
Drug: Nivolumab
Sites in Trumbull, Fairfield +378 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 5 - 60
Code: NCT05675410·Phase 3·Recruiting·Listed Jan 2023
Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma
for Smoldering Plasma Cell Myeloma
Drug: Daratumumab
Sites in Trumbull, Fairfield +486 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: 18+
Code: NCT03937635·Phase 3·Recruiting·Listed May 2019
The CDK4/6 Inhibitor Dosing Knowledge (CDK) Study
for Metastatic Breast Cancer
Sites in Trumbull, Fairfield +71 more locations
Sponsor: American Society of Clinical Oncology
Sex: All·Age: 65+
Code: NCT06377852·Phase 3·Recruiting·Listed Apr 2024
Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas
for Metastatic Dedifferentiated Liposarcoma
Sites in Trumbull, Fairfield +237 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06422806·Phase 3·Recruiting·Listed May 2024
Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment
for Plasma Cell Myeloma
Sites in Trumbull, Fairfield +387 more locations
Sponsor: SWOG Cancer Research Network
Sex: All·Age: All ages
Code: NCT05561387·Phase 3·Recruiting·Listed Sep 2022
Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer
for Previously Treated Non-Small Cell Lung Cancer
Sites in Trumbull, Fairfield +948 more locations
Sponsor: SWOG Cancer Research Network
Sex: All·Age: 18+
Code: NCT03851445·Phase 2, Phase 3·Recruiting·Listed Feb 2019
Comparing the Clinical Impact of Pancreatic Cyst Surveillance Programs and Associated Biomarkers
for Pancreatic Neoplasm
Sites in Trumbull, Fairfield +334 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: 50 - 75
Code: NCT04239573·Recruiting·Listed Jan 2020
Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)
for Recurrent Lung Non-Small Cell Carcinoma
Sites in Trumbull, Fairfield +370 more locations
Sponsor: SWOG Cancer Research Network
Sex: All·Age: 18+
Code: NCT05642572·Phase 2·Recruiting·Listed Dec 2022
Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma
for Recurrent Head and Neck Squamous Cell Carcinoma
Sites in Trumbull, New Haven +127 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18 - 79
Code: NCT04671667·Phase 2·Recruiting·Listed Dec 2020
Comparing Sentinel Lymph Node (SLN) Biopsy With Standard Neck Dissection for Patients With Early-Stage Oral Cavity Cancer
for Buccal Mucosa Squamous Cell Carcinoma
Sites in Trumbull, New Haven +85 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT04333537·Phase 2, Phase 3·Recruiting·Listed Apr 2020
Testing the Combination of the Anticancer Drug Durvalumab With Chemotherapy (Gemcitabine and Cisplatin) at Improving Outcomes for High-Risk Resectable Liver Cancer Before Surgery
for Resectable Intrahepatic Cholangiocarcinoma
Drug: Durvalumab
Sites in Trumbull, Fairfield +50 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06050252·Phase 2·Recruiting·Listed Sep 2023
Observation or Radiation Therapy in Treating Patients With Newly Diagnosed Grade II Meningioma That Has Been Completely Removed by Surgery
for Grade 2 Meningioma
Sites in Trumbull, Hartford +110 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT03180268·Phase 3·Recruiting·Listed Jun 2017
Treatment With Amivantamab and Hyaluronidase or Cetuximab for Advanced Skin Cancer in People With a Weakened Immune System
for Locally Recurrent Skin Squamous Cell Carcinoma
Drug: Amivantamab
Sites in Trumbull, New Haven +40 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT07042295·Phase 2·Recruiting·Listed Jun 2025
Testing the Addition of an Anti-Cancer Drug, Triapine, to the Usual Radiation Therapy for Recurrent Glioblastoma or Astrocytoma
for Astrocytoma, IDH-Mutant, Grade 2
Sites in Trumbull, New Haven +33 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06860594·Phase 1·Recruiting·Listed Mar 2025
QuantifyHER: Quantitative Immunofluorescence and/or RT-qPCR for Measuring HER2 in HER2-low Metastatic Breast Cancer
for HER2-positive Metastatic Breast Cancer
Sites in Trumbull, Fairfield +35 more locations
Sponsor: Abramson Cancer Center at Penn Medicine
Sex: All·Age: 18+
Code: NCT06551116·Recruiting·Listed Aug 2024
Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung Cancer
for Extensive Stage Lung Small Cell Carcinoma
Drug: Atezolizumab
Sites in Trumbull, New Haven +38 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06287775·Phase 1, Phase 2·Recruiting·Listed Mar 2024
Top Research Study Locations in Trumbull
Researchers run research studies in Trumbull, CT at 8 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Smilow Cancer Hospital Care Center-Trumbull | Stage IV Lung Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Extensive Stage Lung Small Cell Carcinoma | 51 |
| Smilow Cancer Hospital - Trumbull | Esophageal Cancer, Advanced Non-Small Cell Lung Cancer, Advanced/Metastatic Solid Tumors | 3 |
| Smilow Cancer Hospital Care Center - Trumbull | Metastatic Breast Cancer, Non-small Cell Lung Cancer | 2 |
| Smilow Cancer Hospital Care Center at Trumbull | Adenocarcinoma, Pancreatic Ductal, Breast Cancer, HER2-positive Breast Cancer | 2 |
| Rett Syndrome Research Trust | Rett Syndrome | 1 |
| Smilow Cancer Hospital Care Center | HER2-positive Metastatic Breast Cancer | 1 |
| Yale New Haven Health Park Avenue Medical Center | Cancer, Chemotherapy-induced Peripheral Neuropathy, Childhood Cancer | 1 |
| ZetrOZ Systems LLC | Bone Fracture, Fresh Fracture | 1 |
Active & Upcoming Studies in Trumbull (2026)
Recruiting trials in Trumbull grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (49 active studies)
- Phase 1 Study of PF-08046033 in Advanced Solid Tumors · Phase 1 · Pfizer
- Treatment With Amivantamab and Hyaluronidase or Cetuximab for Advanced Skin Cancer in People With a Weakened Immune System · Phase 2 · National Cancer Institute (NCI)
Common conditions studied in Trumbull
- Stage IV Lung Cancer AJCC v8 (5 active studies)
- Anatomic Stage II Breast Cancer AJCC v8 (4 active studies)
- Breast Cancer (3 active studies)
- Extensive Stage Lung Small Cell Carcinoma (3 active studies)
- Recurrent Lung Non-Small Cell Carcinoma (3 active studies)
- Advanced Malignant Solid Neoplasm (2 active studies)
Leading research sponsors in Trumbull
- National Cancer Institute (NCI)
- SWOG Cancer Research Network
- NRG Oncology
- Alliance for Clinical Trials in Oncology
- ECOG-ACRIN Cancer Research Group
Frequently asked questions
How many paid clinical trials are currently recruiting in Trumbull?
There are approximately 62 recruiting clinical trials in Trumbull, Connecticut listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Trumbull pay participants?
Most recruiting trials in Trumbull compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Trumbull?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Trumbull?
The most common conditions under active study in Trumbull include Stage IV Lung Cancer AJCC v8 (5), Anatomic Stage II Breast Cancer AJCC v8 (4), Breast Cancer (3), Extensive Stage Lung Small Cell Carcinoma (3), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Trumbull?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Trumbull on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Trumbull?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Trumbull?
Recruiting research sites in Trumbull include Smilow Cancer Hospital Care Center-Trumbull, Smilow Cancer Hospital - Trumbull, Smilow Cancer Hospital Care Center - Trumbull, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Trumbull right now?
The largest active categories in Trumbull are Cancer & tumors (49). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
Browse more clinical trials
Other cities in Connecticut
New Haven, CT(852)Hartford, CT(232)Stamford, CT(83)Waterbury, CT(63)West Haven, CT(62)Farmington, CT(57)Waterford, CT(56)North Haven, CT(53)Greenwich, CT(52)Guilford, CT(51)Fairfield, CT(48)Derby, CT(43)Torrington, CT(39)Glastonbury, CT(33)Bridgeport, CT(29)Hamden, CT(28)Norwalk, CT(24)Danbury, CT(22)New Britain, CT(19)Norwich, CT(17)Cromwell, CT(15)Manchester, CT(15)Orange, CT(14)Storrs, CT(14)Meriden, CT(10)Milford, CT(10)Bristol, CT(7)Avon, CT(6)Westport, CT(6)Branford, CT(5)Darien, CT(5)West Hartford, CT(5)Middlebury, CT(4)Bloomfield, CT(3)Middletown, CT(3)New London, CT(2)Old Saybrook, CT(2)Plainville, CT(2)Brookfield, CT(1)Cheshire, CT(1)Enfield, CT(1)Long Ridge, CT(1)New Britian, CT(1)Ridgefield, CT(1)Southport, CT(1)Storrs Mansfield, CT(1)Willimantic, CT(1)Wilton, CT(1)