Paid Clinical Trials in Wilmington, NC

As of September 2026, 112 paid clinical trials are recruiting in Wilmington, North Carolina. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 11, 2026.

Filter results

Filter results

State

City

Facility

Recruitment status

Phase

Study type

Intervention

Condition

Sex

Age

Healthy volunteers only

98 clinical trials

Get a weekly email when new trials open in Wilmington, NC.

A Study to Evaluate the Effectiveness of IDCT (Intradiscal Cell Therapy) in Subjects With One Level, Symptomatic Mild to Moderate Lumbar Degenerative Disc Disease

for Degenerative Disc Disease

Sites in Wilmington, Winston-Salem +25 more locations

Sponsor: DiscGenics, Inc.

Sex: All·Age: 18 - 75

Code: NCT07254806·Phase 3·Recruiting·Listed Nov 2025

Apply to this trial

Study of AGN-151607-DP to Assess Adverse Events and Change in Disease Activity in Adult Participants Undergoing Open Abdominal Ventral Hernia Repair

for Ventral Hernia

Sites in Wilmington +10 more locations

Sponsor: AbbVie

Sex: All·Age: 18 - 80

Code: NCT07226791·Phase 2·Recruiting·Listed Nov 2025

Apply to this trial

AtraUmatic Laparoscopic HerNia Repair Clinical Investigation to Evaluate the Safety and Performance of The ECLIPSIUM System for Mesh Fixation IDE

for Hernia

Sites in Wilmington, Durham +10 more locations

Sponsor: Tissium

Sex: All·Age: 22+

Code: NCT07277946·Recruiting·Listed Dec 2025

Apply to this trial

Evaluation of IV AMBTX-01 (Neridronate) for Treatment of CRPS Type 1 (CRPS-RISE)

for Complex Regional Pain Syndrome Type I

Sites in Wilmington, Charlotte +25 more locations

Sponsor: Ambros Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07210515·Phase 3·Recruiting·Listed Oct 2025

Apply to this trial

Study of Plozasiran in Adults With Severe Hypertriglyceridemia at Risk of Acute Pancreatitis

for Severe Hypertriglyceridemia

Drug: Plozasiran

Sites in Wilmington, Greensboro +15 more locations

Sponsor: Arrowhead Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06880770·Phase 3·Recruiting·Listed Mar 2025

Apply to this trial

A Study to Assess the Safety and Effectiveness of ELAPR002f Injectable Gel in Adult Participants With Atrophic Acne Scars

for Acne Scars

Sites in Wilmington +9 more locations

Sponsor: AbbVie

Sex: All·Age: 22+

Code: NCT07207369·Phase 3·Recruiting·Listed Oct 2025

Apply to this trial

Evaluation of Efficacy and Safety of THRV-1268 in Long QT Syndrome Type 2 (LQTS 2)

for Long QT Syndrome (LQTS) 2

Sites in Wilmington +8 more locations

Sponsor: Thryv Therapeutics, Inc.

Sex: All·Age: 15+

Code: NCT07277582·Phase 2, Phase 3·Recruiting·Listed Dec 2025

Apply to this trial

A Study to Train a Machine Learning Algorithm for an Evaluation of the Use of Biometric Data Captured at the Wrist for the Identification of Acute Opioid Use Events and the Quantification of Opioid Withdrawal in Opioid Dependent Individuals

for Treatment for Opioid Use Disorder

Sites in Wilmington +3 more locations

Sponsor: OpiAID

Sex: All·Age: 22+·Accepts healthy volunteers

Code: NCT07405398·Recruiting·Listed Feb 2026

Apply to this trial

MOVE: Tenosynovial Giant Cell Tumor (TGCT) Real-World Participant Experience With Vimseltinib

for Tenosynovial Giant Cell Tumor

1 location in Wilmington

Sponsor: Deciphera Pharmaceuticals, LLC

Sex: All·Age: 18+

Code: NCT07075471·Recruiting·Listed Jul 2025

Apply to this trial

Odevixibat Pregnancy and Lactation Surveillance Program: A Study to Evaluate the Safety of Odevixibat During Pregnancy and/or Lactation

for Pregnancy Related

1 location in Wilmington

Sponsor: Ipsen

Sex: Female·Age: All ages

Code: NCT06258902·Recruiting·Listed Feb 2024

Apply to this trial

A Study Evaluating the Effect of BRIUMVI® (Ublituximab) on Pregnancy and Infant Outcomes in Participants With Multiple Sclerosis (MS)

for Multiple Sclerosis

1 location in Wilmington

Sponsor: TG Therapeutics, Inc.

Sex: Female·Age: 15 - 50

Code: NCT06433765·Recruiting·Listed May 2024

Apply to this trial

A Study Evaluating the Presence and Concentration of BRIUMVI™ (Ublituximab) in Breast Milk

for Relapsing Multiple Sclerosis

Sites in Wilmington +4 more locations

Sponsor: TG Therapeutics, Inc.

Sex: Female·Age: 18+

Code: NCT06143514·Recruiting·Listed Nov 2023

Apply to this trial

Real-World Efgartigimod Effectiveness in CIDP: A Prospective Study

for Chronic Inflammatory Demyelinating Polyradiculoneuropathy

1 location in Wilmington

Sponsor: argenx

Sex: All·Age: 18+

Code: NCT07264426·Recruiting·Listed Dec 2025

Apply to this trial

Safety and Effectiveness Evaluation of the High-intensity Focused Ultrasound Device for Lifting Lax Submental and Neck Tissue

for Skin Laxity (Submental and Neck)

Sites in Wilmington, Charlotte +3 more locations

Sponsor: CLASSYS Inc.

Sex: All·Age: 30 - 65·Accepts healthy volunteers

Code: NCT07229430·Recruiting·Listed Nov 2025

Apply to this trial

A Study of Ozanimod in Pregnant Women With Ulcerative Colitis and Their Offspring

for Ulcerative Colitis

1 location in Wilmington

Sponsor: Bristol-Myers Squibb

Sex: Female·Age: All ages

Code: NCT05953402·Recruiting·Listed Jul 2023

Apply to this trial

Observational Study to Assess Maternal, Fetal and Infant Outcomes Following Exposure to Rimegepant

for Migraine

Drug: Rimegepant

1 location in Wilmington

Sponsor: Pfizer

Sex: Female·Age: 0+

Code: NCT05046613·Recruiting·Listed Sep 2021

Apply to this trial

A Study Assessing Safety, Tolerability, and Efficacy of INNA-051 in Preventing Respiratory Illness Due to Viral Infections in Healthy Adults 18 to 45 Years of Age

for Viral Respiratory Infection

Sites in Wilmington, Raleigh +3 more locations

Sponsor: ENA Respiratory Pty Ltd

Sex: All·Age: 18 - 45·Accepts healthy volunteers

Code: NCT07222670·Phase 2·Recruiting·Listed Oct 2025

Apply to this trial

A Global, Multicenter Study to Assess Maternal, Fetal and Infant Outcomes of Exposure to Palynziq® (Pegvaliase) During Pregnancy and Breastfeeding

for Phenylketonuria, Maternal

Drug: Pegvaliase

1 location in Wilmington

Sponsor: BioMarin Pharmaceutical

Sex: Female·Age: All ages

Code: NCT05579548·Recruiting·Listed Oct 2022

Apply to this trial

Mavacamten Pregnancy Surveillance Program

for Breastfeeding

Drug: Mavacamten

1 location in Wilmington

Sponsor: Bristol-Myers Squibb

Sex: Female·Age: 15+

Code: NCT05939700·Recruiting·Listed Jul 2023

Apply to this trial

Relugolix Pregnancy Registry: An Observational Study of the Safety of Relugolix-Containing Therapy Exposure in Pregnant Women and Their Offspring

for Pregnancy Related

Drug: Relugolix

1 location in Wilmington

Sponsor: Sumitomo Pharma Switzerland GmbH

Sex: Female·Age: 0+

Code: NCT05739123·Recruiting·Listed Feb 2023

Apply to this trial

A Study of the Safety of Vonoprazan Exposure in Pregnant Women and Their Offspring

for Erosive Esophagitis

1 location in Wilmington

Sponsor: Phathom Pharmaceuticals, Inc.

Sex: Female·Age: 15 - 50

Code: NCT06660342·Recruiting·Listed Oct 2024

Apply to this trial

SUNOSI® (Solriamfetol) Pregnancy Registry

for Narcolepsy

Drug: Solriamfetol

Sites in Wilmington & Morrisville

Sponsor: Axsome Therapeutics, Inc.

Sex: Female·Age: All ages

Code: NCT06413420·Recruiting·Listed May 2024

Apply to this trial

Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer

for Locally Advanced Cervical Adenocarcinoma

Sites in Wilmington, Raleigh +318 more locations

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT07061977·Phase 3·Recruiting·Listed Jul 2025

Apply to this trial

Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer

for Locally Advanced Lung Non-Small Cell Carcinoma

Sites in Wilmington, Raleigh +444 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05624996·Phase 3·Recruiting·Listed Nov 2022

Apply to this trial

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

for Acute Myeloid Leukemia

Sites in Wilmington, Greenville +326 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05564390·Phase 2·Recruiting·Listed Oct 2022

Apply to this trial

A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

for Ovarian Carcinoma

Sites in Wilmington, Raleigh +479 more locations

Sponsor: NRG Oncology

Sex: Female·Age: 35 - 50

Code: NCT04251052·Recruiting·Listed Jan 2020

Apply to this trial

Anticoagulation in ICH Survivors for Stroke Prevention and Recovery

for Intracerebral Hemorrhage

Sites in Wilmington, Greenville +140 more locations

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT03907046·Phase 3·Recruiting·Listed Apr 2019

Apply to this trial

Isa-Rd for Frail and/or Much Older Patients With Newly Diagnosed Multiple Myeloma

for Multiple Myeloma

Sites in Wilmington, Durham +3 more locations

Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT05145400·Phase 2·Recruiting·Listed Dec 2021

Apply to this trial

Designing Visual Tools to Enhance Cancer Surgeon Decision-making

for Prostate Cancer

Sites in Wilmington & Chapel Hill

Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT06965192·Recruiting·Listed May 2025

Apply to this trial

IBD Pregnancy Registry

for Inflammatory Bowel Disease (IBD)

1 location in Wilmington

Sponsor: CorEvitas

Sex: Female·Age: 18 - 50

Code: NCT06910553·Recruiting·Listed Apr 2025

Apply to this trial

RSV Vaccine Pregnancy Registry

for Respiratory Syncytial Virus (RSV)

1 location in Wilmington

Sponsor: CorEvitas

Sex: Female·Age: 18 - 50·Accepts healthy volunteers

Code: NCT06521944·Recruiting·Listed Jul 2024

Apply to this trial

Antiretroviral Pregnancy Registry (APR): Multi-sponsor Registry to Detect Any Major Teratogenic Effect Involving Any of the Registry Drugs When Administered to Pregnant People.

for HIV Infections

1 location in Wilmington

Sponsor: Syneos Health

Sex: Female·Age: 12 - 60

Code: NCT00404989·Recruiting·Listed Nov 2006

Apply to this trial

A Study to Assess the Safety and Efficacy of AGN-151586 Injections for the Treatment of Moderate to Severe Forehead Lines (FHL) in Adult Participants

for Forehead Lines

Sites in Wilmington +4 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07730554·Phase 2·Recruiting·Listed Jul 28, 2026

Apply to this trial

Study to Determine if BHV-1300 is Effective and Safe in Adults With Graves' Disease

for Graves Disease

Sites in Wilmington, Morehead City +42 more locations

Sponsor: Biohaven Therapeutics Ltd.

Sex: All·Age: 18 - 70

Code: NCT07661056·Phase 3·Recruiting·Listed Jun 2026

Apply to this trial

A Study to Find Out if the Study Drug Elecoglipron Helps Adults With Type 2 Diabetes Mellitus by Comparing it With Semaglutide, a Medicine Already Used to Treat Type 2 Diabetes Mellitus

for Type 2 Diabetes Mellitus

Drug: Semaglutide

Sites in Wilmington, Morehead City +62 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07662213·Phase 3·Recruiting·Listed Jun 2026

Apply to this trial

Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1)

for Obesity

Sites in Wilmington, New Bern +69 more locations

Sponsor: Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics

Sex: All·Age: 18 - 79

Code: NCT07654361·Phase 3·Recruiting·Listed Jun 2026

Apply to this trial

A Phase III Study to Assess the Effect of FDC Laroprovstat/Rosuvastatin Compared With Laroprovstat, Rosuvastatin and Placebo on LDL-C in LLT-naïve Patients.

for Hypercholesterolaemia

Sites in Wilmington, Morehead City +75 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT07619131·Phase 3·Recruiting·Listed Jun 2026

Apply to this trial

Elafibranor Pregnancy Surveillance Program: A Study to Evaluate the Safety of Elafibranor During Pregnancy

for Pregnancy Related

Drug: Elafibranor

1 location in Wilmington

Sponsor: Ipsen

Sex: Female·Age: All ages

Code: NCT07556913·Recruiting·Listed Apr 2026

Apply to this trial

Dose Ranging Study of ORKA-002 in Patients With Moderate-to-Severe Plaque Psoriasis

for Plaque Psoriasis

Sites in Wilmington +28 more locations

Sponsor: Oruka Therapeutics, Inc.

Sex: All·Age: 18 - 79

Code: NCT07474792·Phase 2·Recruiting·Listed Mar 2026

Apply to this trial

Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2

for Gastric Cancer

Drug: Sonesitatug vedotin

Sites in Wilmington, Charlotte +78 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07431281·Phase 3·Recruiting·Listed Feb 2026

Apply to this trial