Paid Clinical Trials in Wilmington, NC
As of July 2026, 107 paid clinical trials are recruiting in Wilmington, North Carolina. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Wilmington offers studies at sites including Novant Health New Hanover Regional Medical Center for conditions such as Obesity, Overweight, Degenerative Disc Disease, Pregnancy Related. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Wilmington
Trials by drug in Wilmington
Filter results
Newly added in Wilmington
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
A Study to Test Whether BI 3034701 Helps People to Lose Weight Who Live With Obesity or Overweight
A Study to Find Out if the Study Drug Elecoglipron Helps Adults With Type 2 Diabetes Mellitus by Comparing it With Semaglutide, a Medicine Already Used to Treat Type 2 Diabetes Mellitus
Study to Determine if BHV-1300 is Effective and Safe in Adults With Graves' Disease
A Research Study Comparing Different Ways of Increasing the Dose of NNC0662-0419 in Participants With Obesity
A Study to Learn About How a New Pneumococcal Vaccine Works in Infants.
93 clinical trials
↓ Download CSVA Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
A Study of PF-08653945 and PF-08653944 in Adults With Overweight or Obesity (SOLIS-1)
A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight
Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) to Maridebart Cafraglutide in Adults With Obesity or Overweight (MARITIME-SWITCH)
A Study to See How Safe and Effective Alirocumab is When Given Weekly to Adult Participants Who Have Hypercholesterolemia
COMO: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME
LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis
A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin
Effectiveness and Adverse-effect Switch Evaluation of Xanomeline and Trospium Chloride (KarXT)
Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D)
A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes
A Study to Learn About a Clostridioides Difficile Vaccine in People 65 Years of Age and Older
OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
REGN7508 Versus Acetylsalicylic Acid (ASA) for Venous Thromboprophylaxis After Total Knee Arthroplasty in Adult Participants
Long-Term Safety Study of Deucravacitinib Versus Ustekinumab in Participants With Psoriasis (PRAGMATYK)
A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)
Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1-Mediated Proteinuric Kidney Disease
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
A Study of Vedolizumab in Adults With Ulcerative Colitis or Crohn's Disease in the Community Setting
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma
Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles)
Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Adults With Moderate to Severe Acne
Prophylactic Reinforcement of Ventral Abdominal Incisions Trial
Long-Term Safety and Efficacy of Plozasiran in Adults With Hypertriglyceridemia
A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)
Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)
Prevail Global Study
Prospective Study to Assess a Diagnostic Aid for Cancer
RESTORE TRIAL: A Phase 2 Study Evaluating the Efficacy and Safety of Pemvidutide in the Treatment of Alcohol-Associated Liver Disease (ALD)
A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants
C-Brace Prospective Registry
Impella RP Flex with Smart Assist
Evaluation of the Tolerability of Cagrilintide in Participants Not Tolerating GLP-1-RA Therapies Due to Gastrointestinal Adverse Events
A Master Protocol (IIBD): A Study of Multiple Drugs in Adults With Ulcerative Colitis or Crohn's Disease
A Study of LY4395089 and Mirikizumab (LY3074828) Given Together and Mirikizumab (Alone) in Adults With Crohn's Disease
AMAZE 12: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Maintain Their Weight Loss
A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
Top Research Study Locations in Wilmington
Researchers run research studies in Wilmington, NC at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Novant Health New Hanover Regional Medical Center | Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm, Acute Myeloid Leukemia Post Cytotoxic Therapy | 12 |
| PPD | Erosive Esophagitis, Heartburn, Helicobacter Pylori Infection | 4 |
| Wilmington Health | Heart Failure, Irritable Bowel Syndrome With Constipation (IBS-C), Long QT Syndrome (LQTS) 2 | 4 |
| Accellacare - Wilmington | Body Weight, Clostridioides Difficile Associated Disease, Nutrition Disorders | 3 |
| Accellacare and KDCILM, LLC | Obesity, Knee Osteoarthritis (OA), Overweight | 3 |
| Atlantic Brain and Spine | Degenerative Disc Disease, Cervical Disc Disease, Cervical Disc Herniation | 3 |
| New Hanover Regional Medical Center | Atrial Fibrillation, Intracerebral Hemorrhage, Kidney Cancer | 3 |
| Wilmington Health, PLLC | Cancer, Clostridioides Difficile Associated Disease, Ulcerative Colitis (UC) | 3 |
| Accellacare Wilmington | Obesity, Heart Failure, Type 2 Diabetes | 3 |
| Accellacare | OSA, Obesity, Overweight | 2 |
| Accellacare Research of Wilmington | Cardiovascular Disease, Obesity or Overweight | 2 |
| Accellacare of Wilmington | Heart Failure With Mildly Reduced Ejection Fraction, Heart Failure With Preserved Ejection Fraction, Hypercholesterolemia | 2 |
| Accellacare-Wilmington-67123 | Cardiovascular Diseases, Diabetes Mellitus, Type 2, Hypertension | 2 |
| Innovo Research - Wilmington Gastroenterology Associates | Crohn Disease, Colitis, Ulcerative | 2 |
| KDCILM, LLC & Accellacare US, Inc. | Diabetes Mellitus, Type 2, Obesity | 2 |
| Novant Health Cancer Institute Radiation Oncology - Wilmington | Locally Advanced Cervical Adenocarcinoma, Locally Advanced Cervical Adenosquamous Carcinoma, Locally Advanced Cervical Squamous Cell Carcinoma | 2 |
| PMG Research of Wilmington, LLC | Type 2 Diabetes, Cortisol Excess, Diabetes Mellitus | 2 |
| PPD Virtual - PPD - US | Schizophrenia, Ulcerative Colitis | 2 |
| Trial Management Associates - Wilmington - Floral Parkway | Obesity, Overweight, Acne | 2 |
| 89bio Clinical Study Site | Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis | 1 |
| ACCOMPLISH-1 Research Site | Chronic Weight Management, Obesity, Overweight | 1 |
| Accellacare - Wilmington - 1917 Tradd Court | Obesity, Overweight | 1 |
| Altimmune Clinical Study Site | Alcohol Liver Disease | 1 |
| Ambros Clinical Trial Site | Complex Regional Pain Syndrome Type I | 1 |
| Anthos Investigative | Atrial Fibrillation (AF) | 1 |
Active & Upcoming Studies in Wilmington (2026)
Recruiting trials in Wilmington grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Diabetes & metabolic (21 active studies)
- AMAZE 9: A Research Study Investigating How Well Zenagamtide Tablets Help People With Excess Body Weight Lose Weight · Phase 3 · Novo Nordisk A/S
- Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1) · Phase 3 · Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
Cancer & tumors (15 active studies)
- Incorporating Biometric Data for Patients Receiving Concurrent Chemotherapy & RT · UNC Lineberger Comprehensive Cancer Center
- Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2 · Phase 3 · AstraZeneca
Cardiovascular (10 active studies)
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
- EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease · Phase 3 · Boehringer Ingelheim
Neurology & pain (5 active studies)
- Evaluation of IV AMBTX-01 (Neridronate) for Treatment of CRPS Type 1 (CRPS-RISE) · Phase 3 · Ambros Therapeutics, Inc.
- A Study Evaluating the Effect of BRIUMVI® (Ublituximab) on Pregnancy and Infant Outcomes in Participants With Multiple Sclerosis (MS) · TG Therapeutics, Inc.
HIV / STI (2 active studies)
- A Phase 2b Study Evaluating Oral VH4524184 Regimens in Treatment Naïve Persons With HIV-1 (INNOVATE Study) · Phase 2 · ViiV Healthcare
- Antiretroviral Pregnancy Registry (APR): Multi-sponsor Registry to Detect Any Major Teratogenic Effect Involving Any of the Registry Drugs When Administered to Pregnant People. · Syneos Health
Vaccines (1 active study)
- RSV Vaccine Pregnancy Registry · CorEvitas
Mental health & behavior (1 active study)
Eye & vision (1 active study)
- COMO: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME · Phase 3 · EyePoint Pharmaceuticals, Inc.
Common conditions studied in Wilmington
- Obesity (14 active studies)
- Overweight (7 active studies)
- Cancer (3 active studies)
- Degenerative Disc Disease (3 active studies)
- Pregnancy Related (3 active studies)
- Type 2 Diabetes (3 active studies)
Leading research sponsors in Wilmington
- Novo Nordisk A/S
- AstraZeneca
- Eli Lilly and Company
- Bristol-Myers Squibb
- Pfizer
Frequently asked questions
How many paid clinical trials are currently recruiting in Wilmington?
There are approximately 107 recruiting clinical trials in Wilmington, North Carolina listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Wilmington pay participants?
Most recruiting trials in Wilmington compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Wilmington?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Wilmington?
The most common conditions under active study in Wilmington include Obesity (14), Overweight (7), Cancer (3), Degenerative Disc Disease (3), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Wilmington?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Wilmington on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Wilmington?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Wilmington?
Recruiting research sites in Wilmington include Novant Health New Hanover Regional Medical Center, PPD, Wilmington Health, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Wilmington right now?
The largest active categories in Wilmington are Diabetes & metabolic (21), Cancer & tumors (15), Cardiovascular (10). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.