Paid Clinical Trials in Wilmington, NC
As of September 2026, 112 paid clinical trials are recruiting in Wilmington, North Carolina. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Wilmington offers studies at sites including Novant Health New Hanover Regional Medical Center for conditions such as Obesity, Overweight, Pregnancy Related, Degenerative Disc Disease. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Wilmington
Trials by drug in Wilmington
Filter results
Newly added in Wilmington
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
Comparative Self-collection for Cervical Cancer Screening Pivotal Study
A Study to Investigate Outcomes With Elecoglipron Compared With Placebo in Adult Participants With Chronic Kidney Disease.
A Study to Evaluate Sequential Administration of Injections of AGN-151586 Followed by BOTOX in Adult Participants for Treatment of Glabellar Lines
Safety and Efficacy of ABBV-295 in Adults With Obesity or Overweight With Weight-Related Comorbidities
A Research Study to Compare Two Different Versions of Injectable Cagrilintide and Placebo in People With Excess Body Weight
98 clinical trials
A Research Study Comparing How Well Different Doses of the Medicine UBT251 Lower Blood Sugar in People With Type 2 Diabetes
A Study to Learn About How a New Pneumococcal Vaccine Works in Infants.
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
A Study of PF-08653945 and PF-08653944 in Adults With Overweight or Obesity (SOLIS-1)
Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) to Maridebart Cafraglutide in Adults With Obesity or Overweight (MARITIME-SWITCH)
A Study to See How Safe and Effective Alirocumab is When Given Weekly to Adult Participants Who Have Hypercholesterolemia
LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis
A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin
A Study to Learn About a Clostridioides Difficile Vaccine in People 65 Years of Age and Older
Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D)
Effectiveness and Adverse-effect Switch Evaluation of Xanomeline and Trospium Chloride (KarXT)
A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events
A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)
Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1-Mediated Proteinuric Kidney Disease
Long-Term Safety Study of Deucravacitinib Versus Ustekinumab in Participants With Psoriasis (PRAGMATYK)
REGN7508 Versus Acetylsalicylic Acid (ASA) for Venous Thromboprophylaxis After Total Knee Arthroplasty in Adult Participants
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Adults With Moderate to Severe Acne
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
A Study of Vedolizumab in Adults With Ulcerative Colitis or Crohn's Disease in the Community Setting
A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles)
A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)
Long-Term Safety and Efficacy of Plozasiran in Adults With Hypertriglyceridemia
Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)
Prevail Global Study
A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants
Prospective Study to Assess a Diagnostic Aid for Cancer
C-Brace Prospective Registry
Impella RP Flex with Smart Assist
A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity
A Research Study Comparing Different Ways of Increasing the Dose of NNC0662-0419 in Participants With Obesity
Evaluation of the Tolerability of Cagrilintide in Participants Not Tolerating GLP-1-RA Therapies Due to Gastrointestinal Adverse Events
Evaluation of the Fully Closed Loop Omnipod® System in Type 2 Diabetes
A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
A Study to Assess the Safety and Efficacy of Different Doses of ELV001 to Treat Active Rheumatoid Arthritis in Patients With an Inadequate Response to Methotrexate and Tumor Necrosis Factor Inhibition (START SYNERGY)
AMAZE 1: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Lose Weight
Top Research Study Locations in Wilmington
Researchers run research studies in Wilmington, NC at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Novant Health New Hanover Regional Medical Center | Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm, Acute Myeloid Leukemia Post Cytotoxic Therapy | 11 |
| Accellacare - Wilmington | Obesity, Overweight, Overweight and/or Obesity | 5 |
| PPD | Erosive Esophagitis, Heartburn, Helicobacter Pylori Infection | 4 |
| Wilmington Health | Heart Failure, Irritable Bowel Syndrome With Constipation (IBS-C), Long QT Syndrome (LQTS) 2 | 4 |
| Accellacare | OSA, Obesity, Overweight | 3 |
| Atlantic Brain and Spine | Degenerative Disc Disease, Cervical Disc Disease, Cervical Disc Herniation | 3 |
| KDCILM, LLC & Accellacare US, Inc. | Obesity, Diabetes Mellitus, Type 2, Overweight | 3 |
| Wilmington Health, PLLC | Cancer, Clostridoides Difficile Associated Disease, Ulcerative Colitis (UC) | 3 |
| Trial Management Associates - Wilmington - Floral Parkway | Overweight, Obesity, Obesity, Abdominal | 3 |
| Wilmington Dermatology Center | Acne Scars, Forehead Lines, Glabellar Lines | 3 |
| Accellacare Research of Wilmington | Cardiovascular Disease, Obesity or Overweight | 2 |
| Accellacare and KDCILM, LLC | Obesity, Knee Osteoarthritis (OA) | 2 |
| Accellacare of Wilmington | Heart Failure With Mildly Reduced Ejection Fraction, Heart Failure With Preserved Ejection Fraction, Hypercholesterolemia | 2 |
| New Hanover Regional Medical Center | Atrial Fibrillation, Intracerebral Hemorrhage, Kidney Cancer | 2 |
| Novant Health Cancer Institute Radiation Oncology - Wilmington | Locally Advanced Cervical Adenocarcinoma, Locally Advanced Cervical Adenosquamous Carcinoma, Locally Advanced Cervical Squamous Cell Carcinoma | 2 |
| PPD Virtual - PPD - US | Schizophrenia, Ulcerative Colitis | 2 |
| Accellacare Wilmington | Heart Failure, Obesity, Hypothyroidism | 2 |
| 89bio Clinical Study Site | Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis | 1 |
| ACCOMPLISH-1 Research Site | Chronic Weight Management, Obesity, Overweight | 1 |
| Accellacare - Tradd Court - Wilmington | Obesity, Overweight | 1 |
| Accellacare - Wilmington - 1917 Tradd Court | Obesity, Overweight | 1 |
| Accellacare-Wilmington-67123 | Cardiovascular Diseases, Diabetes Mellitus, Type 2, Hypertension | 1 |
| Ambros Clinical Trial Site | Complex Regional Pain Syndrome Type I | 1 |
| Anthos Investigative | Atrial Fibrillation (AF) | 1 |
| Atlantic Brain & Spine | Brain Tumor, Brain Tumor - Metastatic, Brain Tumor, Adult Meningioma | 1 |
Active & Upcoming Studies in Wilmington (2026)
Recruiting trials in Wilmington grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Diabetes & metabolic (21 active studies)
- A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity · Phase 3 · Eli Lilly and Company
- A Research Study to Compare Two Different Versions of Injectable Cagrilintide and Placebo in People With Excess Body Weight · Phase 3 · Novo Nordisk A/S
Cancer & tumors (16 active studies)
- Effectiveness of Medical and Environmental Interventions to Reduce Cystoscopy Discomfort (CystoDiscomfort) · Phase 3 · Florian Schroeck
- Incorporating Biometric Data for Patients Receiving Concurrent Chemotherapy & RT · UNC Lineberger Comprehensive Cancer Center
Cardiovascular (12 active studies)
Neurology & pain (5 active studies)
- Evaluation of IV AMBTX-01 (Neridronate) for Treatment of CRPS Type 1 (CRPS-RISE) · Phase 3 · Ambros Therapeutics, Inc.
- A Study Evaluating the Effect of BRIUMVI® (Ublituximab) on Pregnancy and Infant Outcomes in Participants With Multiple Sclerosis (MS) · TG Therapeutics, Inc.
HIV / STI (2 active studies)
- A Phase 2b Study Evaluating Oral VH4524184 Regimens in Treatment Naïve Persons With HIV-1 (INNOVATE Study) · Phase 2 · ViiV Healthcare
- Antiretroviral Pregnancy Registry (APR): Multi-sponsor Registry to Detect Any Major Teratogenic Effect Involving Any of the Registry Drugs When Administered to Pregnant People. · Syneos Health
Vaccines (1 active study)
- RSV Vaccine Pregnancy Registry · CorEvitas
Mental health & behavior (1 active study)
Common conditions studied in Wilmington
- Obesity (13 active studies)
- Overweight (9 active studies)
- Pregnancy Related (4 active studies)
- Cancer (3 active studies)
- Degenerative Disc Disease (3 active studies)
- Heart Failure (3 active studies)
Leading research sponsors in Wilmington
- AstraZeneca
- Novo Nordisk A/S
- AbbVie
- Pfizer
- Bristol-Myers Squibb
Frequently asked questions
How many paid clinical trials are currently recruiting in Wilmington?
There are approximately 112 recruiting clinical trials in Wilmington, North Carolina listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Wilmington pay participants?
Most recruiting trials in Wilmington compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Wilmington?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Wilmington?
The most common conditions under active study in Wilmington include Obesity (13), Overweight (9), Pregnancy Related (4), Cancer (3), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Wilmington?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Wilmington on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Wilmington?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Wilmington?
Recruiting research sites in Wilmington include Novant Health New Hanover Regional Medical Center, Accellacare - Wilmington, PPD, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Wilmington right now?
The largest active categories in Wilmington are Diabetes & metabolic (21), Cancer & tumors (16), Cardiovascular (12). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.