Irinotecan Plus Cyclosporine and Phenobarbital in Treating Patients With Solid Tumors or Lymphoma
Part of paid clinical trials in Chicago, Illinois.
- Sponsor
- National Cancer Institute (NCI)
- Study ID
- NCT00002759
- Phase
- PHASE1
- Status
- Completed
Conditions
- Drug/Agent Toxicity by Tissue/Organ
- Lymphoma
- Neutropenia
- Small Intestine Cancer
- Unspecified Adult Solid Tumor, Protocol Specific
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - N/A
- Healthy Volunteers
- Not accepted
Interventions
- cyclosporine — DRUG
- irinotecan hydrochloride — DRUG
- phenobarbital — DRUG
Study Details
Phase I trial to study the effectiveness of irinotecan plus cyclosporine and phenobarbital in treating patients who have solid tumors or lymphoma that is refractory to standard therapy. Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Cyclosporine and phenobarbital may enhance the effectiveness of irinotecan.
Key Dates
- Start date
- Jun 30, 1996
- Status verified
- May 2006
- Primary completion
- Apr 30, 2002
Study Design
- Enrollment
- 3 participants (actual)
- Allocation
- NA
- Intervention model
- SINGLE_GROUP
- Primary purpose
- TREATMENT
Arms
- Experimental: Arm ISee detailed description.
Locations (1)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| University of Chicago Cancer Research Center | Chicago | Illinois | 60637-1470 | - |
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