Fluorouracil and Leucovorin With or Without Irinotecan in Treating Patients With Metastatic Colorectal Cancer

Sponsor
European Organisation for Research and Treatment of Cancer - EORTC
Study ID
NCT00004885
Phase
PHASE3
Status
Completed

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

Study Details

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known whether fluorouracil and leucovorin plus irinotecan is more effective than fluorouracil and leucovorin alone for colorectal cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of fluorouracil and leucovorin with or without irinotecan in treating patients who have metastatic colorectal cancer.

Key Dates

Start date
Jul 31, 1999
Status verified
Sep 2012
Primary completion
Jul 31, 2001

Study Design

Enrollment
430 participants (actual)
Allocation
RANDOMIZED
Primary purpose
TREATMENT

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