Bevacizumab Plus Capecitabine (Xeloda) in Patients With Untreated Metastatic Colorectal Cancer

Part of paid clinical trials in Alhambra, California.

Sponsor
Translational Oncology Research International
Study ID
NCT00203411
Phase
PHASE2
Status
Completed

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Capecitabine (Xeloda) — DRUG
    1000mg/m\^2 administered orally twice daily for two weeks followed by one week rest period
  • Bevacizumab — DRUG
    7.5 mg/kg IV will be administered every 3 weeks

Study Details

The purpose of this study is to evaluate the safety and effectiveness of the bevacizumab and capecitabine combination in frail patients with untreated metastatic colorectal cancer.

Key Dates

First listed
Sep 20, 2005
Start date
Mar 31, 2006
Status verified
Mar 2016
Primary completion
Mar 31, 2011
Completion
Mar 31, 2011

Study Design

Enrollment
45 participants (actual)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Bevacizumab Plus Capecitabine
    Bevacizumab 7.5 mg/kg every 3 weeks will be administered interavenously (IV) to the enrolled patients. Oral capecitabine 1000 mg/m\^2 twice daily for 14 days followed by 7 days off every 21 days. Treatment will continue until disease progression, unacceptable toxicity, or withdrawal of patient consent.

Primary Outcome Measure

Time to Disease Progression [ Time Frame: 12 months ]

Locations (12)

FacilityCityStateZIPSite coordinators
Central Hematology Oncology Medical Group, Inc.AlhambraCalifornia91801-
Comprehensive Blood and Cancer CenterBakersfieldCalifornia93309-
Virginia K. Crosson Cancer CenterFullertonCalifornia92835-
Pacific Shores Medical GroupLong BeachCalifornia90813-
UCLA Medical CenterLos AngelesCalifornia90095-
North Valley Hematology/Oncology Medical GroupNorthridgeCalifornia91328-
Ventura County Hematology-Oncology SpecialistsOxnardCalifornia93030-
Wilshire Oncology Medical Group, Inc.PomonaCalifornia91767-
Cancer Care Associates Medical Group, Inc.Redondo BeachCalifornia90277-
Santa Barbara Hematology Oncology Medical Group, Inc.Santa BarbaraCalifornia93105-
Central Coast Medical Oncology CorporationSanta MariaCalifornia93454-
Comprehensive Cancer Centers of NevadaLas VegasNevada89109-

Find similar trials in Alhambra, CA

By condition
Colorectal cancer
By specialty
OncologyGI oncology
By research site
Central Hematology Oncology Medical Group, Inc.· Alhambra, CAComprehensive Blood and Cancer Center· Bakersfield, CAVirginia K. Crosson Cancer Center· Fullerton, CAPacific Shores Medical Group· Long Beach, CAUCLA Medical Center· Los Angeles, CANorth Valley Hematology/Oncology Medical Group· Northridge, CA

Related Studies