A Study Comparing Bevacizumab Therapy With or Without Erlotinib for First-Line Treatment of Non-Small Cell Lung Cancer (ATLAS)

Part of paid clinical trials in Mobile, Alabama.

Sponsor: Genentech, Inc.
Study ID: NCT00257608
Phase: PHASE3
Status: Completed

Conditions

Non-Small Cell Lung Cancer

Eligibility Criteria

Sex: ALL
Age: 18 Years - N/A
Healthy Volunteers: Not accepted

Interventions

bevacizumab — DRUG
Intravenous repeating dose
placebo — DRUG
Oral repeating dose
erlotinib HCl — DRUG
Oral repeating dose

Study Details

This is a Phase IIIb, multicenter, randomized, placebo-controlled trial to evaluate the safety and efficacy of chemotherapy+bevacizumab followed by bevacizumab+erlotinib versus bevacizumab+erlotinib placebo in subjects with locally advanced or metastatic NSCLC.

Key Dates

First listed: Nov 23, 2005
Start date: Jan 31, 2006
Status verified: Mar 2016
Primary completion: Nov 30, 2014
Completion: Nov 30, 2014

Study Design

Enrollment: 1,145 participants (actual)
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Arms

Experimental: 1
Placebo Comparator: 2

Primary Outcome Measure

Progression-free Survival (PFS) [ Time Frame: Approximately 3 years ]

Locations (177)

Facility	City	State	ZIP	Site coordinators
Sacred Heart Medical Onc Group	Mobile	Alabama	36608	-
St. Edward Mercy Medical Ctr	Fort Smith	Arizona	72917	-
Mayo Clinic	Scottsdale	Arizona	85259	-
Arizona Cancer Center	Tucson	Arizona	85724	-
Central Hem/Onc Medical Group	Alhambra	California	91801	-
Comp Blood & Cancer Center	Bakersfield	California	93309	-
South Bay Oncology	Campbell	California	95008	-
Bay Area Cancer Research Grp	Concord	California	94598	-
Pacific Onc & Hem Assoc	Encinitas	California	92024	-
Pacific Coast Hem/Onc	Fountain Valley	California	92708	-
Cancer Care Associates	Fresno	California	93720	-
St. Jude Heritage Med Group	Fullerton	California	92835	-
Ronald H. Yanagihara	Gilroy	California	95020	-
Glendale Adventist Medical Ctr	Glendale	California	91206	-
Scipps Clinic	La Jolla	California	92037-1027	-
Loma Linda Univ Medical Center	Loma Linda	California	92354	-
Pacific Shores Medical Group	Long Beach	California	90813	-
Kenmar Research Institute LLC	Los Angeles	California	90057	-
UCLA Medical Ctr	Los Angeles	California	90095	-
Sutter Gould Med Foundation	Modesto	California	95355	-
North Valley Hem Onc Med Grp	Northridge	California	91325	-
Hem Onc Med Grp Orange Cty	Orange	California	92868	-
Medical Oncology Care Assoc	Orange	California	92868	-
Ventura Co Hem-Onc Specialists	Oxnard	California	93030	-
Wilshire Oncology Medical Grp	Pomona	California	91767	-
Mercy General Hospital	Sacramento	California	95819	-
Sutter Cancer Center	Sacramento	California	95816	-
Los Palos Oncology & Hem	Salinas	California	93901	-
Kaiser Permanente	San Diego	California	92120	-
Naval Medical Center	San Diego	California	92134	-
Pacific Hematology Oncology	San Francisco	California	94115	-
Kaiser Permanente Santa Teresa	San Jose	California	95119	-
Sansum Medical Clinic, Inc.	Santa Barbara	California	93105	-
Santa Barbara Hem Onc Med Grp	Santa Barbara	California	93105	-
Central Coast Medical Oncology	Santa Maria	California	93454	-
The Angeles Clinic	Santa Monica	California	90404	-
Redwood Regional Med Grp	Santa Rosa	California	95403	-
Cancer Care Associates	Torrance	California	90505	-
Mile High Oncology	Denver	Colorado	80210	-
Front Range Cancer Specialists	Fort Collins	Colorado	80524	-
Washington Onc Hem Center PC	Washington D.C.	District of Columbia	20037	-
Center for Hematology-Oncology	Boca Raton	Florida	33486	-
Halifax Medical Center	Daytona Beach	Florida	32115	-
Florida Wellcare Alliance	Inverness	Florida	34452	-
Baptist Cancer Institute	Jacksonville	Florida	32207	-
Jackson Memorial Hospital	Miami	Florida	33136	-
Mid-Florida Hem Oncology Ctr	Orange City	Florida	32763	-
Integrated Comm Onc Network	Orange Park	Florida	32073	-
Hematology Onc Treasure Coast	Port Saint Lucie	Florida	34952	-
Phoebe Putney Cancer Center	Albany	Georgia	31701	-
Northeast Georgia Cancer Care	Athens	Georgia	30607	-
Suburban Hem-Onc Associates	Lawrenceville	Georgia	30045	-
Northwest Georgia Onc Centers	Marietta	Georgia	30060	-
Chicagoland Hematology Onc	Arlington Heights	Illinois	60005	-
Weiss-Strauss Oncology Center	Chicago	Illinois	60640	-
LaGrange Oncology Associates	Geneva	Illinois	54301	-
La Grange Oncology Associates	LaGrange	Illinois	60525	-
Associates in Medical Oncology	Oak Lawn	Illinois	60453	-
Onc Hem Assoc of Central IL	Peoria	Illinois	61615	-
West Suburban Cancer Center	River Forest	Illinois	60305	-
OSF St. Anthony Med Ctr	Rockford	Illinois	61108	-
Community Hospital	Munster	Indiana	46321	-
Providence Medical Group	Terre Haute	Indiana	47802	-
Hematology Oncology Associates	Bettendorf	Iowa	52722	-
Siouxland Hem-Onc Assoc LLP	Sioux City	Iowa	51101	-
Covenant Clinic	Waterloo	Iowa	50702	-
Gajera & Patel, PLLC	Hopkinsville	Kentucky	42240	-
Consultants in Blood Disorders	Louisville	Kentucky	40207	-
Kentuckiana Cancer Center	Louisville	Kentucky	40202	-
University of Louisville	Louisville	Kentucky	40202	-
Owensboro Medical Health Sys	Owensboro	Kentucky	42303	-
Willis-Knighton Cancer Center	Shreveport	Louisiana	71103	-
H&J Weinberg Cancer Institute	Baltimore	Maryland	21237	-
Oncology Hematology Associates	Clinton	Maryland	20735	-
Maryland Oncology/Hema PA	Columbia	Maryland	21044	-
Frederick Memorial Hospital	Frederick	Maryland	21701	-
Caritas St. Elizabeth Med Ctr	Boston	Massachusetts	02135	-
Dana Farber Cancer Institute	Boston	Massachusetts	02115	-
Lahey Clinic Med Ctr	Burlington	Massachusetts	01805	-
Metrowest Cancer Center	Framingham	Massachusetts	01702	-
Baystate Medical Center	Springfield	Massachusetts	01107	-
Spectrum Health	Grand Rapids	Michigan	49503	-
Kalamazoo Hem & Onc	Kalamazoo	Michigan	49048	-
Marquette General Health Sys	Marquette	Michigan	49855	-
St. Joseph Mercy Oakland	Pontiac	Michigan	48341	-
William Beaumont Hospital	Royal Oak	Michigan	48073	-
Virginia Piper Cancer Inst	Minneapolis	Minnesota	55407	-
Ellis Fischel Cancer Center	Columbia	Missouri	65203	-
Freeman Cancer Institute	Joplin	Missouri	64804	-
Missouri Cancer Center, PC	Saint Charles	Missouri	63301	-
St. Louis Univ Care Center	St Louis	Missouri	63117	-
Arch Medical Services	Washington	Missouri	63090	-
Billings Clinic	Billings	Montana	59101	-
Big Sky Oncology	Great Falls	Montana	59405	-
Montana Cancer Specialists	Missoula	Montana	59802	-
NE Hematology Oncology, PC	Lincoln	Nebraska	68506	-
Nebraska Methodist Hospital	Omaha	Nebraska	68114	-
Comp Cancer Centers of Nevada	Las Vegas	Nevada	89109	-
Ctr for Cancer & Hem Disease	Cherry Hill	New Jersey	08003	-
Forte, Attas & Schleider	Englewood	New Jersey	07631	-
Hunterdon Medical Center	Flemington	New Jersey	08822	-
Central State Medical Center	Freehold	New Jersey	07728	-
St. Barnabas Health Care Sys	Livingston	New Jersey	07039	-
Mountainside Hospital	Montclair	New Jersey	07042	-
Morristown Memorial Hospital	Morristown	New Jersey	07962	-
Hematology Oncology Assoc SJ	Mount Holly	New Jersey	08060	-
Jersey Shore Medical Center	Neptune City	New Jersey	07754	-
Cancer Institute of New Jersey	New Brunswick	New Jersey	08901	-
The Valley Hospital	Paramus	New Jersey	07652	-
Overlook Hospital	Summit	New Jersey	07902	-
Holy Name Hospital	Teaneck	New Jersey	07666	-
San Juan Onco Assoc	Farmington	New Mexico	87401	-
Zale P Bernstein MD - PP	Buffalo	New York	14215	-
Bassett Cancer Center	Cooperstown	New York	13326	-
Adriondack Cancer Care	Glen Falls	New York	12801	-
BRANY	Great Neck	New York	11021	-
Queens Cancer Center	Jamaica	New York	11432	-
Crystal Run Health Care	Middletown	New York	10941	-
Mem Sloan Kettering Cancer Ctr	New York	New York	10021	-
NYU Medical Center	New York	New York	10016	-
SUNY Upstate	Syracuse	New York	13210	-
Presbyterian Hospital	Charlotte	North Carolina	28204	-
NorthEast Medical Center	Concord	North Carolina	28025	-
Moses Cone Reg Cncr Ctr	Greensboro	North Carolina	27403	-
Emerywood Hematology Oncology	High Point	North Carolina	27262	-
Carolina BioOncology Institute	Huntersville	North Carolina	28078	-
Kinston Medical Specialists	Kinston	North Carolina	28501	-
Beaufort County Hospital	Washington	North Carolina	27889	-
Akron General Medical Center	Akron	Ohio	44307	-
Summa Health System	Akron	Ohio	44304	-
Aultman Hospital	Canton	Ohio	44710	-
Gabrail Cancer Center	Canton	Ohio	44718	-
Onc/Hem Care Clin Trials LLC	Cincinnati	Ohio	45242	-
MetroHealth Medical Center	Cleveland	Ohio	44109	-
Mid Ohio Onc Hematology Inc	Columbus	Ohio	43213	-
Riverside Methodist Hospital	Columbus	Ohio	43214	-
Dayton Clinical Oncology Prog	Dayton	Ohio	45429	-
Ohio Cancer Specialists	Mansfield	Ohio	44907	-
Signal Point Hem/Oncology Inc	Middletown	Ohio	45042	-
Toledo Community Hospital	Toledo	Ohio	43623	-
Forum Health Cancer Care Ctr	Youngstown	Ohio	44501	-
Providence Portland Med Center	Portland	Oregon	97213	-
Ephrata Cancer Center	Ephrata	Pennsylvania	17543	-
Armstrong County Memorial Hosp	Kittanning	Pennsylvania	16201	-
Hem Onc Assoc Phys Lancaster	Lancaster	Pennsylvania	17604	-
University of Pennsylvania	Philadelphia	Pennsylvania	19104	-
Scranton Hematology Oncology	Scranton	Pennsylvania	18510	-
Assoc in Hematology Oncology	Upland	Pennsylvania	19013	-
Lankenau Medical Office Bldg	Wynnewood	Pennsylvania	19096	-
Charleston Cancer Center	Charleston	South Carolina	29406	-
Palmetto Hematology Oncology	Spartanburg	South Carolina	29303	-
Erlanger Health Systems	Chattanooga	Tennessee	37403	-
The Jones Clinic	Germantown	Tennessee	38138	-
Jackson-Madsion County Hosp	Jackson	Tennessee	38301	-
Clopton Clinic	Memphis	Tennessee	38138	-
Sarah Cannon Cancer Center	Nashville	Tennessee	37203-1632	-
Vanderbilt University Medical	Nashville	Tennessee	37232	-
Lone Star Oncology Consultants	Austin	Texas	78759	-
Coastal Bend Cancer Center	Corpus Christi	Texas	78404	-
Texas Cancer Associates	Dallas	Texas	75231	-
Texas Hematology Oncology	Dallas	Texas	75234	-
JPS Center for Cancer Care	Fort Worth	Texas	76104	-
Univ of Texas Medical Branch	Galveston	Texas	77555	-
Wilford Hall Medical Center	Lackland Air Force Base	Texas	78236	-
SW Vermont Healthcare Onc Asoc	Bennington	Vermont	05201	-
Vermont Ctr Cancer Medicine	Colchester	Vermont	05446	-
Community Cancer Center	Rutland	Vermont	05701	-
Peninsula Cancer Institute	Newport News	Virginia	23606	-
SW Virginia Hem Onc	Roanoke	Virginia	24014	-
Cascade Cancer Center	Kirkland	Washington	98034	-
Northwest Medical Specialists	Tacoma	Washington	98405	-
Univ Physicians Internal Med	Huntington	West Virginia	25701	-
West Virginia University	Morgantown	West Virginia	26506	-
Oncology Alliance	Glendale	Wisconsin	53212	-
Dean Clinic	Madison	Wisconsin	53715	-
Medical Consultants LTD	Milwaukee	Wisconsin	53215	-
All Saints Cancer Center	Racine	Wisconsin	53405	-

Find similar trials in Mobile, AL

By condition

Lung cancer

By specialty

Oncology Lung oncology Lung disease

By research site

Sacred Heart Medical Onc Group· Mobile, AL St. Edward Mercy Medical Ctr· Fort Smith, AZ Mayo Clinic· Scottsdale, AZ Arizona Cancer Center· Tucson, AZ Central Hem/Onc Medical Group· Alhambra, CA Comp Blood & Cancer Center· Bakersfield, CA

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