Lung oncology Clinical Trials

Recruiting lung oncology studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat lung oncology. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting lung oncology studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting lung oncology trials

Within

PulmoSalud: Multimodal Program for Prehabilitation and Early Home Rehabilitation in Patients With Lung Cancer

for Lung Cancer

Sponsor: FranciscoVeraSerrano

Sex: All·Age: 18+

Code: NCT07478276

Antigen-specific T Cells Against Lung Cancer

for Lung Cancer

Sponsor: Shenzhen Geno-Immune Medical Institute

Sex: All·Age: 18 - 80

Code: NCT03356808·Phase 1, Phase 2

Multinational Observational Study to Describe Diagnostic Stage Shift in Patients With Lung Cancer Using Medical Records

for Lung Cancer

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06842056

Testing the Impact of an Anti-Cancer Drug, Atezolizumab, After Surgery to Prevent Early Stage Non-small Cell Lung Cancer From Returning, AASI-NSCLC Trial

for Lung Non-Small Cell Carcinoma

59 sites incl. Beverly Hills

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07388524·Phase 3

Apply to this trial

Lung Functional Avoidance Radiotherapy Using Hyperpolarized Xenon MRI

for Carcinoma, Non-Small-Cell Lung

Sponsor: Xemed LLC

Sex: All·Age: 18 - 85

Code: NCT07355231·Phase 1, Phase 2

Witness Project Lung

for Lung Cancer

1 site in Nutley

Sponsor: Hackensack Meridian Health

Sex: All·Age: 50 - 80·Accepts healthy volunteers

Code: NCT07792824

ctDNA-Guided Intraventricular Therapy for CNS Malignancies

for Leptomeningeal Disease

Sponsor: Alireza Mansouri

Sex: All·Age: 18 - 120

Code: NCT07689721

Dissemination Of Lung Cancer Screening Education Through Tobacco Quitlines

for Lung Cancer

1 site in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT07720141

A Multicenter Randomized Open-Label Trial Evaluating ctDNA-Guided Interruption Versus Standard of Care Immune-Checkpoint Inhibitor (ICI) Therapy In Patients With Advanced / Metastatic Solid Tumors.

for NSCLC (Advanced Non-small Cell Lung Cancer)

Sponsor: Natera, Inc.

Sex: All·Age: 18+

Code: NCT07689812

Respiratory Muscle Training in Patients Undergoing Lung Cancer Surgery

for Lung Cancer

Sponsor: Saglik Bilimleri Universitesi

Sex: All·Age: 18 - 70

Code: NCT07499986

A Study Evaluating The Combination of Immunotherapy With Radiotherapy in Non-Small Cell Lung Cancer

for Non-Small Cell Lung Cancer

1 site in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+

Code: NCT07603856·Phase 2

Apply to this trial

3-Dimensional Virtual Reality Modelling With Intravascular Indocyanine Green Fluorescence Mapping for Targeted Pulmonary Segmental Resection Trial

for Non Small Cell Lung Cancer

Sponsor: St. Joseph's Healthcare Hamilton

Sex: All·Age: 18+

Code: NCT06638125·Phase 1, Phase 2

A Study of LG00313112 in Participants With Advanced Solid Malignancies Harboring a TP53 Y220C Mutation

for Ovarian Cancer

Sponsor: LG Chem

Sex: All·Age: 18+

Code: NCT07752875·Phase 1, Phase 2

Phase II Study of Upfront SRT Plus Ivonescimab/Chemotherapy vs Ivonescimab/Chemotherapy in NSCLC Brain Mets

for Non Small Cell Lung Cancer

Sponsor: European Organisation for Research and Treatment of Cancer - EORTC

Sex: All·Age: 18+

Code: NCT07234877·Phase 2

Ph1/2 Trial Of Navlimetostat With Pumitamig In MTAP-Deficient Advanced Non-Small Cell Lung Cancer

for Non-Small Cell Lung Cancer

1 site in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT07579221·Phase 1, Phase 2

Adjuvant ctDNA-Adapted Treatment With Zipalertinib in Early-Stage Atypical EGFR-Mutant NSCLC

for EGFR

Sponsor: Stanford University

Sex: All·Age: 18+

Code: NCT07802834·Phase 2

Prospective Multiomic Analysis in Small-Cell Lung Cancer

for Small Cell Cancer Of The Lung

1 site in Columbus

Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT07795411

An Educational Intervention (Lung Toolkit) for Improving Knowledge About Lung Cancer and Screening Among American Indian and Alaskan Native Cigarette Smokers, Lung PATHS Trial

for Lung Carcinoma

1 site in Seattle

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 50 - 80·Accepts healthy volunteers

Code: NCT07615764

Cemiplimab for Clinical Stage I, 2-3.9cm, Non-Small Cell Lung Cancer

for Non-Small Cell Lung Cancer

1 site in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18 - 80

Code: NCT07720167·Phase 2

A Real World Study of Participants With Non-Small Cell Lung Cancer (NSCLC) With Epidermal Growth Factor Receptor Mutation (EGFRm)

for Carcinoma, Non-Small-Cell Lung

Sponsor: Janssen-Cilag Farmaceutica Ltda.

Sex: All·Age: 18+

Code: NCT07680907

Analysis of Breath Volatile Organic Compounds Using Mass Spectrometry

for Pancreas Cancer

1 site in Oklahoma City

Sponsor: University of Oklahoma

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07732686

OPTIMISE Lung SABR

for Non Small Cell Lung Cancer

Sponsor: Cancer Trials Ireland

Sex: All·Age: 18+

Code: NCT07777614·Phase 2

Impact of Using a GLP1 on Treatment Related Side Effects of Lung Cancer Patients Receiving Lorlatinib

for Lung Cancer

1 site in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+

Code: NCT07782359·Phase 1

A Phase 1, Multicenter Imaging Study of LNTH-2403 in Participants With Locally Advanced or Metastatic Solid Tumors.

for Imaging

Sponsor: Radiopharm Theranostics, Ltd

Sex: All·Age: 18+

Code: NCT07272642·Phase 1

A Study of Targeted Post-Surgery Radiation Therapy for Non-Small Cell Lung Cancer With Remaining Lymph Node Cancer After Treatment

for Lung Non-Small Cell Carcinoma

97 sites incl. Jonesboro

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT07293247·Phase 2

Apply to this trial

Lung Cancer and Aging: Improving Well-being for Older Adults With Lung Cancer

for Lung Cancer

1 site in Durham

Sponsor: Duke University

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT06636721

Surgery After Verifying Existing Disease in Locally Advanced Operable Lung Cancer: A Pilot Study

for Non-Small Cell Lung Cancer

Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)

Sex: All·Age: 18+

Code: NCT06743555·Phase 1

Testing the SurVaxM Vaccine for Lung Cancer Prevention

for Lung Carcinoma

4 sites incl. Aurora

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07169617·Phase 2

SX-682 and Atezolizumab for the Treatment of Advanced or Metastatic, Recurrent Non-small Cell Lung Cancer

for Advanced Lung Non-Small Cell Carcinoma

1 site in Seattle

Sponsor: University of Washington

Sex: All·Age: 18+

Code: NCT07322341·Phase 2

Apply to this trial

Concurrent Immunotherapy and Systemic Therapy With Stereotactic Body Radiation Therapy (SBRT) for Stage IV Cancers (COINSSS IV)

for Head and Neck Cancer

1 site in Lexington

Sponsor: Mark Bernard

Sex: All·Age: 18 - 99

Code: NCT07770100·Phase 2

Totally Robotic Versus Surgeon-Assisted Robotic Lung Resection For Early-Stage NSCLC

for Lung Cancer

Sponsor: St. Joseph's Healthcare Hamilton

Sex: All·Age: 18 - 120

Code: NCT06348030

The Selective Personalized Radio-Immunotherapy for Locally Advanced Non-Small Cell Lung Cancer Trial 2

for Non-small Cell Lung Cancer

1 site in The Bronx

Sponsor: Montefiore Medical Center

Sex: All·Age: 18+

Code: NCT07146230·Phase 2

Fecal Microbiota Transplant(FMT) Combination With Tislelizumab in Advanced or Metastatic NSCLC

for Non Small Cell Lung Cancer

Sponsor: Se-Hoon Lee

Sex: All·Age: 19+·Accepts healthy volunteers

Code: NCT07432984·Phase 2

Study of Izalontamab Brengitecan (BMS-986507) in Combination With Osimertinib Versus Osimertinib Monotherapy or Osimertinib in Combination With Platinum-based Chemotherapy for EGFRmt Non-small Cell Lung Cancer (IZABRIGHT-Lung02)

for Non-Small Cell Lung Cancer

36 sites incl. Beverly Hills

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07680790·Phase 3

A Multicenter Observational PMS Study Assessing Durvalumab Safety in Indian Adults With Resectable NSCLC

for Carcinoma, Non-Small-Cell Lung

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07760519

Prospective Study on Radiation Induced Cardiotoxicity Assessed By PET-CT for Locally Advanced Non-Small Cell Lung Cancer (NSCLC)

for Non Small Cell Lung Cancer

1 site in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 18+

Code: NCT07761910·Phase 2

Apply to this trial

Innovative and Cooperative Pathway Integrating Oncogeriatric, Pharmaceutical and Pharmacological Follow-up in Elderly Patients.

for Elderly

Sponsor: Gustave Roussy, Cancer Campus, Grand Paris

Sex: All·Age: 70+

Code: NCT07802847·Phase 4

DAREON®-36: A Study to Test Obrixtamig in Combination With ZL-1310 in People With Advanced Small Cell Lung Cancer or Other Neuroendocrine Cancers

for Small Cell Lung Cancer

3 sites incl. Washington D.C.

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT07707895·Phase 1, Phase 2

A Study to Assess Intravenous ABBV-1480 Combined With Chemotherapy Versus Pembrolizumab Combined With Chemotherapy for the First Line Treatment of Locally Advanced/Metastatic Non-Small Cell Lung Cancer in Adult Participants

for Non-Small Cell Lung Cancer

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07756645·Phase 3

Lumbar Punctures for the Detection of ctDNA in the Cerebrospinal Fluid of Patients With Stage III and IV Non-Small Cell Lung Cancer

for Lung Non-Small Cell Carcinoma

1 site in Columbus

Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All·Age: All ages

Code: NCT06816979

Tailored Patient Navigation to Improve the Uptake of Lung Cancer Screening in Tribal Communities in Western Washington State, SACRED LUNGS Trial

for Lung Carcinoma

2 sites incl. Auburn

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07176000

Apply to this trial

Study for Evaluating the Safety and Feasibility of Fecal Microbiota Transplant in Stage II-III NSCLC Patients Using ICI Responders as Donors (MIGRANT)

for Non Small Cell Lung Cancer

Sponsor: Fundación GECP

Sex: All·Age: 18+

Code: NCT07247786·Phase 2

Home-Based Respiratory Muscle Training and Aerobic Exercise Programs to Improve Lung Health in Current and Former Cigarette Smokers

for Lung Carcinoma

1 site in Buffalo

Sponsor: Roswell Park Cancer Institute

Sex: All·Age: 50+·Accepts healthy volunteers

Code: NCT07553819

A PET Imaging Agent (64Cu-DOTA-Pembrolizumab) for Determining Treatment Response Among Patients With Stage IV Non-small Cell Lung Cancer Receiving Pembrolizumab

for Metastatic Lung Non-Small Cell Carcinoma

1 site in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT07619599·Phase 1

Apply to this trial

A Study of a Side Effects and Resource Navigation Program for People With Cancer

for Kidney Cancer

8 sites incl. Basking Ridge

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT07646847

Apply to this trial

SMARCA4/2 Inhibitor for POU2F3-Positive SCLC

for Small Cell Lung Cancer

1 site in Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT07551635·Phase 2

Vapor Ablation for Localized Cancer Lesions

for Non Small Cell Lung Cancer

Sponsor: Uptake Medical Technology, Inc.

Sex: All·Age: 18+

Code: NCT03514329

DK222 Study at Hopkins

for Non-Small Cell Lung Cancer

1 site in Baltimore

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: 18+

Code: NCT07140315·Phase 1

Apply to this trial

A New Way to Share Radiation Therapy Plans Between Doctors, CORRECT Trial

for Lung Carcinoma

1 site in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07282444

SPARC - Screening for Lung Cancer With Platelets Via an AI-enabled RNA-based Classifier

for Lung Cancer

2 sites in Salt Lake City

Sponsor: University of Utah

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT07460440

Apply to this trial

A Restorative Justice-Based Lung Cancer Screening Decision-Making Support Intervention Tailored for Black Individuals to Increase Lung Cancer Screening Among Black Community Members, RESTORE Trial

for Lung Carcinoma

1 site in Seattle

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 50 - 77·Accepts healthy volunteers

Code: NCT07490860

Apply to this trial

A Study to Evaluate the Efficacy and Safety of Divarasib Compared With Investigator's Choice of Immunotherapy or Observation in Participants With Resected Stage II-III KRAS G12C-Positive Non-Small Cell Lung Cancer (NSCLC)

for Non-small Cell Lung Cancer

1 site in Clovis

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT07541170·Phase 3

Apply to this trial

Low Dose, Reduced Frequency Nivolumab for the Treatment of Unresectable or Metastatic Cancer, AFFORD IO Trial

for Clinical Stage III Cutaneous Melanoma AJCC v8

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 18+

Code: NCT07576725·Phase 2

A Non-interventional, Real-world Study on the Adjuvant Treatment of Chinese EGFR-positive Stage IA NSCLC Patients With High-risk Factors Using Third-generation EGFR-TKIs.

for Non-Small Cell Lung Cancer

Sponsor: First Affiliated Hospital of Guangxi Medical University

Sex: All·Age: 18+

Code: NCT07686185

In Vitro NSCLC EGFR-Mutant Models for Drug Sensitivity Testing

for Carcinoma, Non-Small-Cell Lung

Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Sex: All·Age: 18+

Code: NCT07697716

Adaptive Chemotherapy for Pd-l1 High REsEctablE NSCLC: A Chemo-PHREE Trial

for Nsclc

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18+

Code: NCT07746388·Phase 2

Feasibility and Uptake of Low-Dose CT Lung Cancer Screening in Kuwait

for Lung Cancer

Sponsor: Sulaiman Khadadah

Sex: All·Age: 50 - 80·Accepts healthy volunteers

Code: NCT07766538

Lung Cancer Screening Implementation Project in the Brazilian Public Health Care System (LUSIP)

for Lung Cancer

Sponsor: AstraZeneca

Sex: All·Age: 50 - 80

Code: NCT07279948

Tarlatamab for SCLC Brain Metastases

for Small Cell Lung Cancer

Sponsor: Maastricht University Medical Center

Sex: All·Age: 18+

Code: NCT07402343·Phase 2

Apply to this trial

TCR1188-ABC Cells in KRAS-mutated Cancers

for Cholangiocarcinoma

1 site in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT07594067·Phase 1

Apply to this trial

New trials in Los Angeles, CA?

Pick a condition and we'll email you once a week when a new study starts recruiting in Los Angeles, CA. Unsubscribe anytime.

Lung oncology clinical trials — common questions

Are lung oncology clinical trials free to join?

Yes. Participating in a lung oncology clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a lung oncology clinical trial?

Each lung oncology study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a lung oncology trial near me?

Use the location controls above. We'll show recruiting lung oncology trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many lung oncology trials are recruiting right now?

We're currently tracking roughly 579 recruiting lung oncology trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Lung oncology trials by city

Los Angeles, CA Boston, MA Duarte, CA Birmingham, AL Chicago, IL Aurora, CO Orange, CA Beverly Hills, CA La Jolla, CA Sacramento, CA Seattle, WA Columbus, OH

Conditions in this area

Lung cancer Non-small cell lung cancer (NSCLC)Small cell lung cancer Mesothelioma