RAD001 Plus Bevacizumab in Metastatic Melanoma

Part of paid clinical trials in Fort Myers, Florida.

Sponsor
SCRI Development Innovations, LLC
Study ID
NCT00591734
Phase
PHASE2
Status
Completed

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Bevacizumab — DRUG
    15 mg/kg of bevacizumab intravenously (IV) once every 3 weeks.
  • Everolimus — DRUG
    10 mg by mouth daily

Study Details

This is a non-randomized, open label Phase II study comparing bevacizumab and everolimus in the treatment of metastatic melanoma.

Key Dates

First listed
Jan 11, 2008
Start date
Jan 31, 2008
Status verified
Nov 2021
Primary completion
Oct 31, 2010
Completion
Oct 31, 2011

Study Design

Enrollment
57 participants (actual)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Intervention
    All patients received bevacizumab 15 mg/kg, administered by intravenous (IV) infusion on day 1 of each 21 day course. In addition, patients received everolimus 10 mg orally on a daily basis.

Primary Outcome Measure

Progression-free Survival [ Time Frame: 13 months ]

Locations (15)

FacilityCityStateZIPSite coordinators
Florida Cancer SpecialistsFort MyersFlorida33901-
Watson Clinic Center for Cancer Care and ResearchLakelandFlorida33805-
Florida Hospital Cancer InstituteOrlandoFlorida32804-
Gulfcoast Oncology AssociatesSt. PetersburgFlorida33705-
Northeast Georgia Medical CenterGainesvilleGeorgia30501-
Oncology Hematology Associates of SW IndianaEvansvilleIndiana47714-
Center for Cancer and Blood DisordersBethesdaMaryland20817-
Grand Rapids Clinical Oncology ProgramGrand RapidsMichigan49503-
St. Louis Cancer CareChesterfieldMissouri63017-
Methodist Cancer CenterOmahaNebraska68114-
Consultants in Medical Oncology and HematologyDrexel HillPennsylvania19026-
Chattanooga Oncology & Hematology AssociatesChattanoogaTennessee37404-
Tennessee Oncology, PLLCNashvilleTennessee37023-
South Texas Oncology and HematologySan AntonioTexas78258-
Virginia Cancer InstituteRichmondVirginia23235-

Find similar trials in Fort Myers, FL

By condition
Melanoma
By specialty
OncologySkin cancerDermatology
By research site
Florida Cancer Specialists· Fort Myers, FLWatson Clinic Center for Cancer Care and Research· Lakeland, FLFlorida Hospital Cancer Institute· Orlando, FLGulfcoast Oncology Associates· St. Petersburg, FLNortheast Georgia Medical Center· Gainesville, GAOncology Hematology Associates of SW Indiana· Evansville, IN

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