Radiation Therapy to the Brain or Observation in Preventing Brain Metastases in Patients With Advanced Non-Small Cell Lung Cancer

Sponsor
National Cancer Center, Korea
Study ID
NCT00955695
Phase
PHASE3
Status
Unknown

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • erlotinib hydrochloride — DRUG
  • gefitinib — DRUG
  • questionnaire administration — OTHER
  • quality-of-life assessment — PROCEDURE
  • whole-brain radiation therapy — RADIATION

Study Details

RATIONALE: Radiation therapy to the brain may be effective in preventing brain metastases in patients with advanced non-small cell lung cancer. It is not yet known whether radiation therapy is more effective than observation in patients with advanced non-small cell lung cancer. PURPOSE: This randomized phase III trial is studying radiation therapy to the brain to see how well it works compared with observation in preventing brain metastases in patients with advanced non-small cell lung cancer.

Key Dates

First listed
Aug 10, 2009
Start date
May 31, 2009
Status verified
Jan 2010

Study Design

Enrollment
242 participants (estimated)
Allocation
RANDOMIZED
Primary purpose
PREVENTION

Primary Outcome Measure

Time to symptomatic brain metastases

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