Results of Adjunctive Intraoperative Bevacizumab Injection on Trabeculectomy Outcome

Sponsor
Prince of Songkla University
Study ID
NCT01263834
Phase
PHASE2/PHASE3
Status
Completed

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 80 Years
Healthy Volunteers
Not accepted

Interventions

  • Bevacizumab — DRUG
    Bevacizumab injection of 1.25m/0.05 cc + Mitomycin C soaked cellulose dose 0.4 mg/ml with 3 minutes of application
  • Mitomycin C — DRUG
    Mitomycin C soaked cellulose dose 0.4 mg/ml with 3 minutes of application

Study Details

The purpose of this study is to evaluate the adjunctive effect of intratenon Bevacizumab on the result of trabeculectomy in primary term of intraocular pressure (IOP).

Key Dates

First listed
Dec 21, 2010
Start date
Dec 31, 2010
Status verified
Jan 2014
Primary completion
Jan 31, 2014
Completion
Jan 31, 2014

Study Design

Enrollment
39 participants (actual)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Active Comparator: Mitomycin c
    Mitomycin C soaked cellulose dose 0.4 mg/ml with 3 minutes of application
  • Experimental: Bevacizumab
    Bevacizumab injection of 1.25m/0.05 cc + Mitomycin C soaked cellulose dose 0.4 mg/ml with 3 minutes of application

Primary Outcome Measure

Intraocular pressure [ Time Frame: 6 month ]

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