Problem Adaptation Therapy for Mild Cognitive Impairment and Depression

Part of paid clinical trials in Baltimore, Maryland.

Sponsor
Weill Medical College of Cornell University
Study ID
NCT03043573
Status
Completed

Conditions

Eligibility Criteria

Sex
ALL
Age
60 Years - 85 Years
Healthy Volunteers
Not accepted

Interventions

  • PATH-MCI — BEHAVIORAL
    Problem Adaptation Therapy for Mild Cognitively Impaired Adults (PATH-MCI) differs from standard of care psychotherapy by offering a combination of emotion regulation techniques with the provision of environmental adaptation tools (notes, checklists, calendars, etc.), the use of the WellPATH app, and the participation of a willing and available caregiver.
  • Supportive Therapy — BEHAVIORAL
    ST focuses on: 1. facilitating expression of affect; 2. conveying to the patient that he or she is understood; 3. offering empathy; and 4. highlighting positive experiences. The ST manual aims to standardize nonspecific therapeutic factors.

Study Details

The present collaborative R01 study, between Cornell and Johns Hopkins, aims to compare Problem Adaptation Therapy for Mild Cognitively Impaired Older Adults (PATH-MCI) vs. Supportive Therapy for Cognitively Impaired Older Adults (ST-CI) in improving cognitive, affective, and functioning outcomes.

Key Dates

Start date
Jul 1, 2017
Status verified
Jul 2025
Primary completion
Sep 19, 2024
Completion
Sep 19, 2024

Study Design

Enrollment
80 participants (actual)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION

Arms

  • Experimental: PATH-MCI
    Problem Adaptation Therapy for Mild Cognitively Impaired Adults (PATH-MCI) differs from standard of care psychotherapy by offering a combination of emotion regulation techniques with the provision of environmental adaptation tools (notes, checklists, calendars, etc.), the use of the WellPATH app, and the participation of a willing and available caregiver.
  • Active Comparator: Supportive Therapy
    Supportive Therapy focuses on: 1. Facilitating expression of affect; 2. Conveying to the patient that he or she is understood; 3. Offering empathy; and 4. Highlighting positive experiences. The ST manual aims to standardize nonspecific therapeutic factors.

Primary Outcome Measure

Change in Global Cognition Assessed by RBANS [ Time Frame: Baseline, 12, 24, and 52 Weeks ]

Locations (4)

FacilityCityStateZIPSite coordinators
Johns Hopkins University School of MedicineBaltimoreMaryland21224-
Weill Cornell MedicineNew YorkNew York10065-
Montefiore Medical CenterThe BronxNew York10461-
Weill Cornell Institute of Geriatric Psychiatry, Weill Cornell MedicineWhite PlainsNew York10605-

Find similar trials in Baltimore, MD

By condition
Depression
By specialty
PsychiatryMental healthBehavioral health
By research site
Johns Hopkins University School of Medicine· Baltimore, MDWeill Cornell Medicine· New York, NYMontefiore Medical Center· The Bronx, NYWeill Cornell Institute of Geriatric Psychiatry, Weill Cornell Medicine· White Plains, NY

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