EMPagliflozin outcomE tRial in Patients With chrOnic heaRt Failure With Reduced Ejection Fraction (EMPEROR-Reduced)

Part of paid clinical trials in La Mesa, California.

Sponsor
Boehringer Ingelheim
Study ID
NCT03057977
Phase
PHASE3
Status
Completed

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

Study Details

The aim of the study is to investigate the safety and efficacy of empagliflozin versus placebo on top of guideline-directed medical therapy in patients with heart failure with reduced ejection fraction.

Key Dates

Start date
Mar 6, 2017
Status verified
Apr 2021
Primary completion
May 1, 2020
Completion
May 28, 2020

Study Design

Enrollment
3,730 participants (actual)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Empagliflozin
  • Placebo Comparator: Placebo

Primary Outcome Measure

Time to the First Event of Adjudicated Cardiovascular (CV) Death or Adjudicated Hospitalisation for Heart Failure (HHF) [ Time Frame: From randomisation until completion of the planned treatment period, up to 1040 days. ]

Locations (92)

FacilityCityStateZIPSite coordinators
La Mesa Cardiac CenterLa MesaCalifornia91942-
Long Beach Center for Clinical ResearchLong BeachCalifornia90807-
VA Greater Los Angeles Healthcare SystemLos AngelesCalifornia90073-
Merced Vein and Vascular CenterMercedCalifornia95340-
University of California IrvineOrangeCalifornia92865-
Covigilant Research, LLCRiversideCalifornia92506-
University of CaliforniaTorranceCalifornia90502-
Orange County Research CenterTustinCalifornia92780-
Blue Coast CardiologyVistaCalifornia92083-
South Denver Cardiology Associates, PCLittletonColorado80120-
Integrated Heart CareBoca RatonFlorida33434-
Morton Plant Mease Health CareClearwaterFlorida33756-
Nature Coast Clinical ResearchCrystal RiverFlorida34429-
Avail Clinical Research, LLCDeLandFlorida32720-
Holy Cross HospitalFort LauderdaleFlorida33308-
Integrative Research AssociatesFort LauderdaleFlorida33312-
Nature Coast Clinical ResearchInvernessFlorida34452-
East Coast Institute for Research, LLCJacksonvilleFlorida32216-
Jacksonville Center for Clinical ResearchJacksonvilleFlorida32216-
Cardiovascular Research Center of South FloridaMiamiFlorida33173-
Peninsula Research, Inc.Ormond BeachFlorida32174-
Cardiology Consultants, IncPensacolaFlorida32501-
Sarasota Memorial HospitalSarasotaFlorida34239-
Grady Clinical Research CenterAtlantaGeorgia30303-
Augusta UniversityAugustaGeorgia30912-
Columbus Regional Research InstituteColumbusGeorgia31904-
Cardiovascular Group PCLawrencevilleGeorgia30046-
Meridian Clinical Research, LLCSavannahGeorgia31406-
Northwest Heart Clinical Research, LLCArlington HeightsIllinois60005-
University of ChicagoChicagoIllinois60637-
Captain James A. Lovell Federal Health Care CenterNorth ChicagoIllinois60064-
Rockford Cardiovascular AssociatesRockfordIllinois61107-
Midwest Cardiovascular Research and Education FoundationElkhartIndiana46514-
St. Francis Medical Group-Indiana Heart Physicians, IncIndianapolisIndiana46237-
Reid HospitalRichmondIndiana47374-
Beacon Medical Group Clinical ResearchSouth BendIndiana46601-
Research Integrity, LLCOwensboroKentucky42303-
Cambridge Medical TrialsAlexandriaLouisiana71301-
Louisiana Heart CenterCovingtonLouisiana70433-
Clinical Trials of America, LLCMonroeLouisiana71201-
Tulane University Hospital and ClinicNew OrleansLouisiana70112-
Anne Arundel Medical CenterAnnapolisMaryland21401-
Johns Hopkins University Hospital School of MedicineBaltimoreMaryland21205-
MedStar Health Research InstituteBaltimoreMaryland21237-
Metropolitan Cardiovascular ConsultantsBeltsvilleMaryland20705-
Spectrum Clinical ResearchTowsonMaryland21204-
Tufts Medical CenterBostonMassachusetts02111-
East Mountain Medical Associates, PCGreat BarringtonMassachusetts01230-
Alpena General HospitalAlpenaMichigan49707-
Regions HospitalSaint PaulMinnesota55101-
Saint Louis UniversitySt LouisMissouri63110-
SLHVSt LouisMissouri63136-
Palm Research CenterLas VegasNevada89148-
Advanced Heart Care, LLCBridgewaterNew Jersey08807-
Trinity Medical WNY, PCCheektowagaNew York14227-
Northwell HealthGreat NeckNew York11021-
Mount Sinai School of MedicineLake SuccessNew York11041-
Harlem CardiologyNew YorkNew York10035-
St. Luke's Roosevelt HospitalNew YorkNew York10025-
Stony Brook University Medical CenterStony BrookNew York11794-
Cardiac Care and Vascular Medicine, PLLCThe BronxNew York10469-
Asheville Cardiology AssociatesAshevilleNorth Carolina28803-
Kernodle Clinic WestBurlingtonNorth Carolina27215-
The University of North Carolina at Chapel HillChapel HillNorth Carolina27599-5021-
Novant Health Heart and Vascular InstituteCharlotteNorth Carolina28204-
Duke University Medical CenterDurhamNorth Carolina27609-
Clinical Research of GastoniaGastoniaNorth Carolina28054-
Clinical Trials of America, IncLenoirNorth Carolina28645-
Rama Research LLCMarionOhio43302-
University of ToledoToledoOhio43614-
South Oklahoma Heart Research GroupOklahoma CityOklahoma73135-
Doylestown Health CardiologyDoylestownPennsylvania18901-
York Hospital, WellSpan HealthYorkPennsylvania17403-
AnMed Health Clinical ResearchAndersonSouth Carolina29621-
Ralph H. Johnson VA Medical CenterCharlestonSouth Carolina29401-
Palmetto HealthColumbiaSouth Carolina29203-
William Jennings Bryan Dorn VA Medical CenterColumbiaSouth Carolina29209-
Clinical Research of Rock HillRock HillSouth Carolina29732-
Palmetto Research Center, LLCSpartanburgSouth Carolina29302-
Methodist University HospitalMemphisTennessee38104-
Baylor Heart and Vascular HospitalDallasTexas75226-
Soltero Cardiovascular Research CenterDallasTexas75226-
University of Texas Southwestern Medical CenterDallasTexas75390-8837-
University of North Texas Health Science CenterFort WorthTexas76107-
The Methodist HospitalHoustonTexas77030-
The Heart HospitalPlanoTexas75093-
Alpine Research OrganizationFarmingtonUtah84025-
Cardiac Health Management Network, P.C.ChesterVirginia23836-
Hunter Holmes McGuire VA Medical CenterRichmondVirginia23249-
Roanoke Heart Institute PLCRoanokeVirginia24014-
Salem VA Medical CenterSalemVirginia24153-
Marshfield ClinicMarshfieldWisconsin54449-

Find similar trials in La Mesa, CA

By condition
Heart failure
By specialty
CardiologyHeart disease
By research site
La Mesa Cardiac Center· La Mesa, CALong Beach Center for Clinical Research· Long Beach, CAVA Greater Los Angeles Healthcare System· Los Angeles, CAMerced Vein and Vascular Center· Merced, CAUniversity of California Irvine· Orange, CACovigilant Research, LLC· Riverside, CA

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