Optimizing Cognitive Remediation

Part of paid clinical trials in San Diego, California.

Sponsor
VA Office of Research and Development
Study ID
NCT04395157
Status
Completed

Conditions

  • Generalized Anxiety Disorder
  • Mood Disorders
  • Schizophrenia
  • Stress Disorders, Post-Traumatic

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Study Details

Veterans with mental illness face challenges with community reintegration, including achieving vocational success, attaining their educational goals and going back to school, and maintaining a high quality of life. VA Mental Health Residential Rehabilitation Treatment Programs, Psychosocial Rehabilitation and Recovery Centers and other mental health treatment programs are designed to help Veterans overcome these barriers, but cognitive impairment often seen in Veterans with mental illness limits gains from these settings. Cognitive remediation interventions can be helpful, but they are either "one-size fits all," and thus may not be useful for all Veterans with mental illness, or are too narrow in scope, focusing on specific mental illnesses, limiting generalizability. This project will test whether an objective neurophysiological biomarker, mismatch negativity (MMN), can better match the "right" Veteran to the "right" cognitive remediation treatment regardless of their specific mental health diagnosis.

Key Dates

Start date
Dec 1, 2020
Status verified
Feb 2026
Primary completion
Jan 1, 2025
Completion
Apr 30, 2025

Study Design

Enrollment
100 participants (actual)

Arms

  • Arm: Veterans engaged in VA mental health rehabilitation/recovery
    Veterans must be within 6 weeks of discharge from or current receive mental health treatment services in a VA San Diego Healthcare System psychosocial rehabilitation and recovery center (PRRC), mental health residential rehabilitation treatment program (RRTP), general mental health outpatient treatment, or recent acute mental health inpatient hospitalization.

Primary Outcome Measure

MATRICS Consensus Cognitive Battery Global Composite T-score (MCCB-C) [ Time Frame: Baseline visit ]

Locations (1)

FacilityCityStateZIPSite coordinators
VA San Diego Healthcare System, San Diego, CASan DiegoCalifornia92161-0002-

Find similar trials in San Diego, CA

By condition
Schizophrenia
By specialty
PsychiatryMental healthBehavioral health
By research site
VA San Diego Healthcare System, San Diego, CA· San Diego, CA

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