Schizophrenia Clinical Trials

Recruiting schizophrenia studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat schizophrenia. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting schizophrenia studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting schizophrenia trials

Within

Personalized Pharmaco-Lifestyle Interventions for Severe Mental Illnesses (LIFETRAIN)

for Severe Mental Illness

Sponsor: Ludwig-Maximilians - University of Munich

Sex: All·Age: 18 - 65

Code: NCT07586150

Developing a Virtual Reality-assisted Intervention for Emotion Regulation Difficulties in Psychosis

for Psychosis

Sponsor: King's College London

Sex: All·Age: 18+

Code: NCT07623928

Frontal Gamma Coherence Neurofeedback for Patients With Schizophrenia

for Schizophrenia

1 site in La Jolla

Sponsor: BioSignal Solutions LLC

Sex: All·Age: 18 - 55

Code: NCT07659938

Shared Decision Making for Antipsychotic Medications

for Schizophrenia

Sponsor: New York State Psychiatric Institute

Sex: All·Age: 18 - 30

Code: NCT05416658

Brain Network Mechanisms of Cognitive Impairments in Major Psychiatric Disorders and Their Clinical Applications

for Schizophrenia

Sponsor: Central South University

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT07444463

Mobile Thinking Intervention: A Inital Test

for Schizophrenia

1 site in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18 - 65

Code: NCT06909422

Feasibility and Acceptability of Mobile Mental Health App for SZ and SZA

for Schizophrenia

Sponsor: University of Pittsburgh

Sex: All·Age: 18 - 60

Code: NCT06474325

Longitudinal PET Imaging of Antipsychotic Binding to the Dopamine-3 Receptor in Schizophrenia

for Schizoaffective Disorder

Sponsor: New York State Psychiatric Institute

Sex: All·Age: 18 - 55

Code: NCT07715253·Phase 1

Digital Implementation Support to Achieve Uptake and Integration of Task-Shared Care for Schizophrenia in Primary Care in India

for Schizophrenia

Sponsor: Harvard Medical School (HMS and HSDM)

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06043778

Optimizing CBSST With Executive Function Training for Schizophrenia (R33)

for Schizophrenia

2 sites incl. San Diego

Sponsor: University of California, San Diego

Sex: All·Age: 60+

Code: NCT07658391

Relapse Prevention Trial Evaluating KarXT Treatment in Schizophrenia

for Schizophrenia

33 sites incl. Bentonville

Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Sex: All·Age: 18 - 65

Code: NCT07686263·Phase 3

Clinical Trial of an IL-23 Inhibitor for Immune Activation in Clinical Trial of an IL-23 Inhibitor for Immune Activation in People With Schizophrenia

for Schizophrenia

1 site in Catonsville

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18 - 64·Accepts healthy volunteers

Code: NCT07615075·Phase 4

Online Intervention To Improve Motivation

for Schizophrenia Prodromal

1 site in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18 - 65

Code: NCT07157293

Exploring the Genetics of Schizophrenia in Manitoba

for Schizophrenia

Sponsor: University of Manitoba

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07656870

Overnight Thalamic TES-TI to Modulate Sleep Spindles in Individuals With Schizophrenia Spectrum Disorders and Matched Healthy Controls

for Schizophrenia

1 site in Madison

Sponsor: University of Wisconsin, Madison

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT07680114

Pilot Study of Sensor-Informed Smartphone-based Mental Health Interventions for Mood in Early Psychosis

for Psychosis

1 site in Belmont

Sponsor: Mclean Hospital

Sex: All·Age: 18 - 50

Code: NCT07503093

Prucalopride for Cognitive Functioning in Schizophrenia

for Schizophrenia

Sponsor: University of Pittsburgh

Sex: All·Age: 18 - 55

Code: NCT06474286

Evaluate Pharmacokinetics, Safety, and Tolerability of AX251 LAI in Patients With Schizophrenia

for Schizophrenia

Sponsor: Anxo Pharmaceutical Co., Ltd.

Sex: All·Age: 18 - 65

Code: NCT07484204·Phase 1

Evaluating Safety and Efficacy of VV119 in Acute Schizophrenia Adults

for Schizophrenia

Sponsor: Vigonvita Life Sciences

Sex: All·Age: 18 - 65

Code: NCT07703956·Phase 2

Cognitive Strategies in Early Psychosis 2

for Psychosis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 35

Code: NCT07263022·Phase 3

tACS for Working Memory in Schizophrenia

for Schizophrenia

Sponsor: Central South University

Sex: All·Age: 18 - 50

Code: NCT07701343

Apply to this trial

Study to Evaluate the Safety and Efficacy of Ublituximab in Participants With Schizophrenia

for Schizophrenia

2 sites incl. Little Rock

Sponsor: TG Therapeutics, Inc.

Sex: All·Age: 18 - 60

Code: NCT07680946·Phase 2

Apply to this trial

Enhancing Veteran-Clinical Collaboration in VA PRRCs

for Schizophrenia

3 sites incl. San Diego

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT06898879

Eye-Movement Intervention for Cognitive Impairment Across Schizophrenia Spectrum

for Schizophrenia

Sponsor: Shanghai Mental Health Center

Sex: All·Age: 15 - 45·Accepts healthy volunteers

Code: NCT07702526

MicroRNAs as Biomarkers in First Episode Schizophrenia

for Schizophrenia Disorder

1 site in Glen Oaks

Sponsor: Northwell Health

Sex: All·Age: 15 - 40·Accepts healthy volunteers

Code: NCT07703670

Apply to this trial

Stratification and Treatment in Early Psychosis Study -ASSIST

for Treatment Resistant Psychosis

Sponsor: University of Oxford

Sex: All·Age: 16 - 50

Code: NCT07326124·Phase 3

The Effect of Comorbid Alcohol/Substance Use

for Alcohol Abuse

Sponsor: Abant Izzet Baysal University

Sex: All·Age: 18 - 65

Code: NCT07692984

Apply to this trial

Transcranial Sonography and Machine Learning for Schizophrenia Identification

for Schizophrenia

Sponsor: Taizhou Second People's Hospital

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07604129

Investigation of the Effects of Angling as Supportive Therapy in Schizophrenia Treatment on Serum Parameters, Anxiety, Depression, and Quality of Life

for Angling

Sponsor: Firat University

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT07682935

Apply to this trial

REACH Study (Recovery Environments: Assessing Cognitive & Brain Health in Community Mental Health)

for Schizophrenia

1 site in Cleveland

Sponsor: Case Western Reserve University

Sex: All·Age: 18 - 50

Code: NCT07006935

Multimodal Intervention to Support Hospital-to-Community Transition in Bipolar Disorder

for Bipolar Disorder (BD)

Sponsor: McMaster University

Sex: All·Age: 18 - 35

Code: NCT07213492

Apply to this trial

Impact of Cannabis Consumption on Psychotic Symptoms and Reality Monitoring in Patients With Schizophrenia: a Real-life Study

for Schizophrenia

Sponsor: Centre Hospitalier Charles Perrens, Bordeaux

Sex: All·Age: 18 - 65

Code: NCT07309159·Phase 1, Phase 2

A 20-Year Follow-up of First Episode Psychosis: Longitudinal Effects of Early Treatment Strategies and Relapse

for Schizophrenia

Sponsor: The University of Hong Kong

Sex: All·Age: 18 - 65

Code: NCT07616999

Apply to this trial

A Phase I Clinical Trial to Evaluate the Safety, Tolerability and Pharmacokinetic Characteristics of KR23248 Capsules in Healthy Adult Subjects

for Schizophrenia

Sponsor: Jiangxi Kvvit Pharmaceutical Co., Ltd.

Sex: All·Age: 18 - 45·Accepts healthy volunteers

Code: NCT07585383·Phase 1

The Mouth Matters in Mental Health Trial -2

for Mental Health

Sponsor: Lancashire and South Cumbria NHS Foundation Trust

Sex: All·Age: 18+

Code: NCT07470437

52-week Open Label Safety-Tolerability Study

for Schizophrenia

23 sites incl. Chandler

Sponsor: LB Pharmaceuticals Inc.

Sex: All·Age: 18 - 65

Code: NCT07369154·Phase 3

Emotional Eating, Sleep Quality, Mental State and Metabolic Syndrome

for Schizophrenia

Sponsor: Abant Izzet Baysal University

Sex: All·Age: 18 - 65

Code: NCT07411222

Venous Tourniquet vs. Arterial Tourniquet for Seizure Monitoring in ECT

for Major Depressive Disorder

Sponsor: Medipol University

Sex: All·Age: 18 - 65

Code: NCT07534475

Effects of Gamified Rehabilitation on Cognitive and Psychosocial Outcomes in Inpatients With Schizophrenia

for Schizophrenia

Sponsor: Shanghai Mental Health Center

Sex: All·Age: 18 - 45

Code: NCT07557368

Apply to this trial

The Effect of Game-Based Intervention on the Cognition of Schizophrenia Patients

for Schizophrenia

Sponsor: Shanghai Mental Health Center

Sex: All·Age: 18 - 45

Code: NCT07557381

Apply to this trial

A Study to Evaluate the Long-term Safety and Tolerability of KarXT and KarX-EC for the Treatment of Schizophrenia and Autism-Related Irritability in Adolescents, Respectively

for Schizophrenia

51 sites incl. Dothan

Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Sex: All·Age: 5 - 17

Code: NCT07424404·Phase 3

Apply to this trial

Steady-state Bioequivalence Study of Aripiprazole for Injection in Patients With Schizophrenia.

for Schizophrenia

Sponsor: CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd.

Sex: All·Age: 18 - 65

Code: NCT07547384

A Phase 2 Study to Evaluate the Efficacy and Safety of LY03020 in Acutely Psychotic Participants With Schizophrenia

for Schizophrenia

Sponsor: Luye Pharma Group Ltd.

Sex: All·Age: 18 - 65

Code: NCT07396870·Phase 2

A Long-Term Open-Label Study of ML-007C-MA in Adults With Schizophrenia

for Schizophrenia

5 sites incl. Lemon Grove

Sponsor: MapLight Therapeutics

Sex: All·Age: 18 - 65

Code: NCT07459647·Phase 2

Apply to this trial

Effects of Action-Based Cognitive Remediation on Substance Misuse in Early Phase Psychosis

for Psychosis

Sponsor: Nova Scotia Health Authority

Sex: All·Age: 16 - 30

Code: NCT07056894

Apply to this trial

A Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-5)

for Alzheimer Disease

5 sites incl. Gilbert

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 55 - 90

Code: NCT06947941·Phase 3

Apply to this trial

Study to Evaluate LB-102 for the Treatment of Adult Patients With Acute Schizophrenia

for Schizophrenia

13 sites incl. Bentonville

Sponsor: LB Pharmaceuticals Inc.

Sex: All·Age: 18 - 65

Code: NCT07363577·Phase 3

Apply to this trial

A Study to Detect the Radioactivity of 14C-SEP-380135 in Urine and Feces in Healthy Male Adults

for Schizophrenia

1 site in Lincoln

Sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc.

Sex: Male·Age: 18 - 55·Accepts healthy volunteers

Code: NCT07455084·Phase 1

Study to Assess the Safety, Tolerability, and Treatment Response of GXV813 in Hospitalized Adults With Schizophrenia

for Schizophrenia

7 sites incl. Bentonville

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 65

Code: NCT07467993·Phase 2

Apply to this trial

Incentives and Long-Acting Injectable Adherence After Involuntary Hospitalization

for Schizophrenia Disorder

5 sites in Pittsburgh

Sponsor: Stanford University

Sex: All·Age: 18 - 65

Code: NCT07130500

LRFN5 and OLFM4 in Schizoaffective Disorder

for Schizoaffective Disorder

Sponsor: Elazığ Mental Health and Diseases Hospital

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07447960

A Study of the Feasibility, Safety and Tolerability of Aticaprant as Adjunctive Treatment in Participants With Schizophrenia

for Schizophrenia

8 sites incl. Garden Grove

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18 - 55

Code: NCT07615426·Phase 1

Apply to this trial

Improving Health Literacy in Patients With Schizophrenia Spectrum Disorder

for Schizophrenia Disorder

1 site in New Orleans

Sponsor: Louisiana State University Health Sciences Center in New Orleans

Sex: All·Age: 18 - 65

Code: NCT07488156

Stratification and Treatment in Early Psychosis Study - ENHANCE

for Psychosis

Sponsor: University of Oxford

Sex: All·Age: 16 - 40

Code: NCT06778564·Phase 3

Effectiveness and Adverse-effect Switch Evaluation of Xanomeline and Trospium Chloride (KarXT)

for Schizophrenia

52 sites incl. Bryant

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07379827

Apply to this trial

A Case Series of Culturally-adapted CBTp for Black People in the UK

for Psychosis

Sponsor: University of Manchester

Sex: All·Age: 16+

Code: NCT07252206

Apply to this trial

Effectiveness of Exercise Alone and tDCS+Exercise on Cognitive Function Improvement in Patients With Treatment Resistant Schizophrenia

for Schizophrenia

Sponsor: Kit Wa Chan

Sex: All·Age: 18 - 60

Code: NCT07404319

Evaluation of NBI-1117570 in Inpatient Adults With Schizophrenia

for Schizophrenia

Sponsor: Neurocrine Biosciences

Sex: All·Age: 18 - 55

Code: NCT07288333·Phase 2

Apply to this trial

PQQ for Cognitive and Negative Symptoms

for Schizophrenia

Sponsor: Tianjin Anding Hospital

Sex: All·Age: 18 - 50

Code: NCT07393464

Comparison of Accelerated Intermittent Theta Burst Stimulation vs High Frequency Transcranial Magnetic Stimulation (Hf-rTMS) on Cognitivesymptoms in Treatment-resistant Schizophrenia

for Psychosis

Sponsor: All India Institute of Medical Sciences, Bhubaneswar

Sex: All·Age: 18 - 60

Code: NCT07445620

Schizophrenia clinical trials — common questions

Are schizophrenia clinical trials free to join?

Yes. Participating in a schizophrenia clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a schizophrenia clinical trial?

Each schizophrenia study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a schizophrenia trial near me?

Use the location controls above. We'll show recruiting schizophrenia trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many schizophrenia trials are recruiting right now?

We're currently tracking roughly 120 recruiting schizophrenia trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Schizophrenia trials by city

Little Rock, AR San Diego, CA Los Angeles, CA Birmingham, AL Garden Grove, CA Anaheim, CA La Jolla, CA Palo Alto, CA San Francisco, CA Aurora, CO

Related specialties

Psychiatry Mental health Behavioral health