Cognitive Fitness for Depression in Older Adults

Part of paid clinical trials in Farmington, Connecticut.

Sponsor
UConn Health
Study ID
NCT04790630
Status
Completed

Conditions

Eligibility Criteria

Sex
ALL
Age
60 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Computerized Cognitive Remediation of Executive Functioning (CCR-EF) — OTHER
    computerized experimental brain-training treatment
  • Active Control — OTHER
    computerized intervention that follows recommendations for cognitive fitness

Study Details

This research is being done to determine if computerized administered cognitive fitness activities will improve thinking and depression in older depressed adults who are being treated with antidepressants. The investigators are also interested in whether participating in the treatment will result in changes to brain activity measured with magnetic resonance imaging (MRI).

Key Dates

Start date
Nov 15, 2020
Status verified
Apr 2026
Primary completion
Oct 15, 2024
Completion
Oct 15, 2024

Study Design

Enrollment
38 participants (actual)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Computerized Cognitive Remediation of Executive Functioning (CCR-EF)
    Initially 10 hours of processing speed exercises from "Brain HQ", (the 3 exercises are auditory tone sweep, visual processing \[Double Decision\], visual sweep). Following the 8-10 hours of Brain HQ, participants complete 8-10 hours of "Ultimate Word Master" before completing 16-20 hours of "Neurogrow" (formerly called "Catch the Ball"). Participants are asked to complete approximately 28-42 hours of computerized brain training over 4-6 weeks.
  • Active Comparator: Active Control
    Patients in the active control arm will complete three activities according to a standard protocol: 1) play a visuospatially oriented computer game (Myst), 2) watch computer-based educational programs on art, history, literature, and 3) play computer games online through the Brain HQ platform; games include crossword puzzles, soduko, paddleboard, and word search. Participants will complete a total of 32-42 hours of training over 4-6 weeks. Time spent on each task will be evenly divided (15 minutes of each task everday).

Primary Outcome Measure

Trail Making Part B Test [ Time Frame: Pre-treatment and six weeks later when treatment has ended ]

Locations (1)

FacilityCityStateZIPSite coordinators
UConn HealthFarmingtonConnecticut06030-

Find similar trials in Farmington, CT

By condition
Depression
By specialty
PsychiatryMental healthBehavioral health
By research site
UConn Health· Farmington, CT

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