Rocklatan® Evaluation

Part of paid clinical trials in Mission Hills, California.

Sponsor
Aerie Pharmaceuticals
Study ID
NCT05283395
Phase
PHASE4
Status
Completed

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Netarsudil 0.02%/latanoprost 0.005% fixed dose combination ophthalmic solution — DRUG
    Commercially available ophthalmic solution indicated for the reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension

Study Details

The objective of this study is to evaluate the IOP-lowering effect when subjects are switched from various latanoprost-based regimens to Rocklatan. Subjects will stop their IOP-lowering medical therapy regimen and dose with Rocklatan for the duration of the study (12 weeks).

Key Dates

Start date
Mar 28, 2022
Status verified
Jan 2024
Primary completion
Mar 22, 2023
Completion
Mar 22, 2023

Study Design

Enrollment
136 participants (actual)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Rocklatan
    Netarsudil 0.02%/latanoprost 0.005% fixed dose combination ophthalmic solution, one drop in each eye in the evening for 12 weeks

Primary Outcome Measure

Mean Percent Change From Baseline in Intraocular Pressure (IOP) at Week 12 [ Time Frame: Baseline (Day 0 pretreatment), Week 12 ]

Locations (21)

FacilityCityStateZIPSite coordinators
North Valley Eye Medical GroupMission HillsCalifornia91345-
Visionary Eye InstituteNewport BeachCalifornia92663-
California Eye Specialists Medical GroupPasadenaCalifornia91107-
North Bay Eye AssociatesPetalumaCalifornia94954-
Shettle Eye ResearchLargoFlorida33773-
Center For SightVeniceFlorida34285-
Georgia Eye PartnersAtlantaGeorgia30342-
Coastal Research Associates LLCRoswellGeorgia30076-
Tekwani Vision CenterSt LouisMissouri63128-
OCLI VisionManhassetNew York11030-
Mark J. Weiss, MD, Inc.TulsaOklahoma74104-
Scott & Christie and Associates, PCCranberry TownshipPennsylvania16066-
Advancing Vision ResearchGoodlettsvilleTennessee37072-
Total Eye Care, PAMemphisTennessee38199-
VRF Eye Specialty GroupMemphisTennessee38120-
Keystone ResearchAustinTexas78731-
Louis M. Alpern, M.D., M.P.H., P.AEl PasoTexas79902-
Houston Eye AssociatesHoustonTexas77025-
Emerson Clinical Research InstituteFalls ChurchVirginia22046-
Vistar Eye CenterRoanokeVirginia24016-
The Eye Centers of Racine and KenoshaRacineWisconsin53405-

Find similar trials in Mission Hills, CA

By condition
Glaucoma
By specialty
Ophthalmology
By research site
North Valley Eye Medical Group· Mission Hills, CAVisionary Eye Institute· Newport Beach, CACalifornia Eye Specialists Medical Group· Pasadena, CANorth Bay Eye Associates· Petaluma, CAShettle Eye Research· Largo, FLCenter For Sight· Venice, FL

Related Studies