Transcranial Direct Current Stimulation Therapy for Bipolar Depression

Sponsor
University of East London
Study ID
NCT05436613
Status
Completed

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Transcranial Direct Current Stimulation — DEVICE
    tDCS at 2mA in 30 minute sessions for 5 sessions per week for 3 weeks and then 2 sessions per week for 3 weeks.

Study Details

Bipolar disorder is a severe and disabling disorder. The course of illness is often progressive but is highly heterogeneous between individuals and within the lifetime for an individual. The most common treatments are medications. However, for many individuals, combinations of medications are often required, and full recovery is infrequent. The novel brain stimulation treatment, transcranial direct current stimulation (tDCS), is a potential first-line treatment for bipolar depression. The present research question is whether tDCS can be provided as a home-based treatment for bipolar depression for adults with bipolar disorder.

Key Dates

Start date
May 1, 2022
Status verified
Jul 2025
Primary completion
May 30, 2024
Completion
May 30, 2024

Study Design

Enrollment
44 participants (actual)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Device: transcranial direct current stimulation
    6-week course of active tDCS treatment, consisting of 5 sessions per week for the first 3 weeks followed by 2 sessions per week for 3 weeks, for a total of 21 tDCS sessions. The duration of each session is 30 minutes.

Primary Outcome Measure

Number of Participants With Clinical Response [ Time Frame: At 6 Weeks Following Course of tDCS Treatment ] [ Time Frame: 6 weeks ]

Related Studies