Background of Different Phenotypes of Coeliac Disease

Sponsor
Tampere University Hospital
Study ID
NCT05597904
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • Genetic predisposition — GENETIC
    Assessment of genetic predisposition to various celiac disease phenotypes. No intervention.

Study Details

The main purpose of this study is to investigate genetic, serological, immunological and microbiata diversities between different coeliac disease phenotypes and to discover applicable prognostic markers for specific phenotypes.

Key Dates

First listed
Oct 28, 2022
Start date
Nov 8, 2022
Status verified
Sep 2025
Primary completion
Dec 31, 2027
Completion
Dec 31, 2030

Study Design

Enrollment
3,500 participants (estimated)

Arms

  • Arm: Coeliac disease patients
    Adult (18 years or over) patients with previous coeliac disease or dermatitis herpetiformis diagnosis
  • Arm: Healthy controls
    500 adult (18 years or over) friends or non-related family members of coeliac disease or dermatitis herpetiformis patients participating in the study, no previous coeliac disease or dermatitis herpetiformis diagnosis. In addition 1000 controls will be included from Biobank

Primary Outcome Measure

Non-HLA variant association [ Time Frame: baseline ]

Central Contacts

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