The Purpose of This Study is to Evaluate the Effects of Ruxolitinib Cream on Adults With Atopic Dermatitis Experiencing Sleep Disturbance.

Part of paid clinical trials in Fountain Valley, California.

Sponsor
Incyte Corporation
Study ID
NCT05696392
Phase
PHASE4
Status
Terminated

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • ruxolitinib cream — DRUG
    ruxolitinib cream 1.5% will be applied twice daily as a thin film

Study Details

The purpose of the study is to evaluate the effect of ruxolitinib cream on sleep disturbances with participants with Atopic Dermatitis.

Key Dates

Start date
Mar 16, 2023
Status verified
Dec 2025
Primary completion
Jan 22, 2025
Completion
Jan 22, 2025

Study Design

Enrollment
47 participants (actual)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Treatment Group: Ruxolitinib
    ruxolitinib cream 1.5% will be applied twice daily (BID) as a thin film.

Primary Outcome Measure

Change From Baseline in Total Sleep Time (TST) as Measured by Ōura Ring Wearable Device at Week 8 [ Time Frame: Baseline; Week 8 ]

Locations (30)

FacilityCityStateZIPSite coordinators
First Oc DermatologyFountain ValleyCalifornia92708-
Ark Clinical ResearchLong BeachCalifornia90815-
Gw Training CenterWashington D.C.District of Columbia20037-
Skin Care Research, LlcBoca RatonFlorida33486-
Driven Research LlcCoral GablesFlorida33134-
University of Florida Health Dermatology-SpringhillGainesvilleFlorida32606-
Skin Care Research, Llc Scr HollywoodHollywoodFlorida33021-
Ciocca Dermatology PaMiamiFlorida33173-
Trueblue Clinical ResearchTampaFlorida33609-
Dermatology Specialists Research IndianaClarksvilleIndiana47129-
Dawes Fretzin Clinical Research Group LlcIndianapolisIndiana46250-
Skin Sciences PllcLouisvilleKentucky40217-
Beth Israel Deaconess Medical Center (Bidmc)BostonMassachusetts02215-
Northeast Dermatology AssociatesMethuenMassachusetts01844-
Essential DermatologyNatickMassachusetts01760-
Washington University School of Medicine DermatologySt LouisMissouri63110-
Suny Downstate Health Sciences UniversityBrooklynNew York11203-
Empire DermatologyEast SyracuseNew York13057-
Sadick DermatologyNew YorkNew York10075-
Skin Search of RochesterRochesterNew York14623-
Ohio Pediatric Research AssociationDaytonOhio45414-
Knight Cancer Institute At Oregon Health and Science UniversityPortlandOregon97239-
Oregon Dermatology and Research CenterPortlandOregon97210-
University of PittsburghPittsburghPennsylvania15213-
Clinical Research Center of the CarolinasCharlestonSouth Carolina29407-
Arlington Research CenterArlingtonTexas76011-
Jordan Valley Dermatology CenterSouth JordanUtah84095-
Pi Coor Clinical Research LlcBurkeVirginia22015-
Clinical Research Partners LlcRichmondVirginia23226-
Dermatology Specialists of SpokaneSpokaneWashington99202-

Find similar trials in Fountain Valley, CA

By condition
Atopic dermatitis / eczema
By specialty
DermatologyRheumatologyAutoimmune disease
By research site
First Oc Dermatology· Fountain Valley, CAArk Clinical Research· Long Beach, CAGw Training Center· Washington D.C., DCSkin Care Research, Llc· Boca Raton, FLDriven Research Llc· Coral Gables, FLUniversity of Florida Health Dermatology-Springhill· Gainesville, FL

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