Rheumatology Clinical Trials

Q: Are rheumatology clinical trials free to join?

Yes. Participating in a rheumatology clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Q: Who can join a rheumatology clinical trial?

Each rheumatology study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

Q: How do I find a rheumatology trial near me?

Use the location controls above. We'll show recruiting rheumatology trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

Q: How many rheumatology trials are recruiting right now?

We're currently tracking roughly 268 recruiting rheumatology trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Recruiting rheumatology studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat rheumatology. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting rheumatology studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting rheumatology trials

Within

Effect of S. Aureus Skin Decolonization on Disease Severity in Atopic Dermatitis Patients

for Atopic Dermatitis

1 site in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 6+

Code: NCT06397781·Phase 4

Apremilast and Adalimumab in Psoriatic Arthritis Patients

for Psoriatic Arthritis

Sponsor: Tanta University

Sex: All·Age: 18 - 70

Code: NCT07398651

Safety and Tolerability of a Single Intravenous Infusion of BX-U001 in Refractory Rheumatoid Arthritis

for Rheumatoid Arthritis

Sponsor: Baylx Inc.

Sex: All·Age: 18 - 70

Code: NCT03828344·Phase 1

Study to Characterise Pharmacokinetics (PK), Pharmacodynamics (PD), and Safety of Anifrolumab Administered Subcutaneously (SC) or Intravenously (IV)

for Systemic Lupus Erythematosus

Sponsor: AstraZeneca

Sex: All·Age: 18 - 70

Code: NCT07688980·Phase 1

A Study of Early Secukinumab Treatment in Moderate to Severe Hidradenitis Suppurativa Patients

for Hidradenitis Suppurativa

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07690319

Saphnelo Use in Females of Child-bearing Potential

for Systemic Lupus Erythematosus

Sponsor: AstraZeneca

Sex: Female·Age: 15 - 50

Code: NCT07431775

Evaluation of Serum IL-41 Level in Patients With Ankylosing Spondylitis and Psoriatic Arthritis

for Ankylosing Spondylitis

Sponsor: Assiut University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07648836

A Randomised Controlled Trial of ePROM-Guided Flexible Scheduling in Dermatology

for Chronic Dermatological Conditions

Sponsor: National University Hospital, Singapore

Sex: All·Age: 16+

Code: NCT07481019

A Trial in Healthy Adult Participants and Adults With Autoimmune Disease to Test How HBM7020 is Tolerated and Absorbed in the Body

for Rheumatoid Arthritis

Sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc.

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT07649265·Phase 1

Safety and Efficacy of ONT01 in Lupus

for Lupus Nephritis (LN)

1 site in New York

Sponsor: Hospital for Special Surgery, New York

Sex: All·Age: 18+

Code: NCT07107659·EARLY_Phase 1

Apply to this trial

Nailfold Capillaroscopic Changes in Psoriasis

for Psoriasis

Sponsor: Al-Azhar University

Sex: All·Age: All ages

Code: NCT07693595

The ROOT Study: Scaling the 'Standard of Care Plus' Obstetric Nutrition Model to Optimize Maternal and Infant Health

for Preterm Birth

Sponsor: GrowBaby Life Project

Sex: Female·Age: 18+

Code: NCT07559773

Opzelura Experience Study

for Atopic Dermatitis

1 site in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 2+

Code: NCT07661979·Phase 4

Efficacy and Tolerability of a Probiotic Ointment

for Atopic Dermatitis

Sponsor: BioGaia AB

Sex: All·Age: 6 Months - 15

Code: NCT07701447

Combined Fractional CO₂ Laser and Topical Corticosteroid Versus Topical Corticosteroid Only in the Treatment of Palmoplantar Psoriasis

for Psoriasis

Sponsor: Cairo University

Sex: All·Age: 18 - 60

Code: NCT07713212·Phase 4

Utilization of a Microdevice for Psoriasis and Atopic Dermatitis

for Psoriasis

1 site in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT07352566·Phase 4

Azithromycin in Atopic Dermatitis

for Atopic Dermatitis

Sponsor: Cairo University

Sex: All·Age: 3 - 12

Code: NCT07713186·Phase 4

US Zamto-cel Autoimmune Diseases

for Lupus Nephritis

1 site in Milwaukee

Sponsor: Miltenyi Biomedicine GmbH

Sex: All·Age: 18+

Code: NCT06708845·Phase 1

Apply to this trial

Assessing Psoriasis Treatment Outcomes

for Psoriasis

1 site in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT07391423

A Real-world Study of Patients With Hidradenitis Suppurativa and High Cardiovascular Risk or Established Coronary Plaque Treated With Secukinumab

for Hidradenitis Suppurativa

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 75

Code: NCT07454889

RD06-05 Universal CD19/BCMA CAR-T for Refractory Pediatric Autoimmune Diseases

for Autoimmune Diseases

Sponsor: The Children's Hospital of Zhejiang University School of Medicine

Sex: All·Age: 5 - 20

Code: NCT07674147·EARLY_Phase 1

A Study of C-CAR168 in the Treatment of Autoimmune Diseases Refractory to Standard Therapy

for Multiple Sclerosis (MS)

Sponsor: The Affiliated Hospital of Qingdao University

Sex: All·Age: 18 - 70

Code: NCT07676266·Phase 1

A Clinical Study of HRS-8797 in Healthy Participants

for Atopic Dermatitis

Sponsor: Chengdu Suncadia Medicine Co., Ltd.

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT07698756·Phase 1

A Study to Investigate Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Anifrolumab in Pediatric Participants 5 to < 18 Years of Age With Systemic Lupus Erythematosus

for Systemic Lupus Erythematosus

Sponsor: AstraZeneca

Sex: All·Age: 5 - 17

Code: NCT07630714·Phase 2

Deciphering the Genetic Architecture of Autoimmune Diseases

for Autoimmune Diseases

Sponsor: National Human Genome Research Institute (NHGRI)

Sex: All·Age: 18 - 115

Code: NCT06948110

Apply to this trial

Evaluating the Safety and Tolerability of Baricitinib in Patients With Job Syndrome With Lupus-Like Disease and/or Atopic Dermatitis

for Hyper IgE Syndrome From STAT3 Mutation

1 site in Bethesda

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 12 - 120

Code: NCT07262983·Phase 1

Apply to this trial

A Phase 1, First-in-Human Study of CND319 in Healthy Participants and Patients With Rheumatic Diseases

for Healthy Participants Study

Sponsor: Candid Therapeutics

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07712939·Phase 1

Apply to this trial

Natrunix in Combination With Methotrexate for Rheumatoid Arthritis Treatment

for Rheumatoid Arthritis

Sponsor: XBiotech, Inc.

Sex: All·Age: 18+

Code: NCT06590090·Phase 2

An Extension Study to Assess Safety and Efficacy of Remibrutinib in Participants With Moderate to Severe HS

for Hidradenitis Suppurativa

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 100

Code: NCT07665437·Phase 3

Apply to this trial

Phase 1b/2 Study of IV Sarilumab in Adult With RA

for Rheumatoid Arthritis

2 sites incl. Hollywood

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT07704580·Phase 1, Phase 2

Apply to this trial

Therapeutic Drug Monitoring of Mycophenolate Mofetil in Lupus Nephritis

for Systemic Lupus Erythematosus

Sponsor: Federal University of Maranhao

Sex: All·Age: 18+

Code: NCT07493655

A Phase 2, Open-Label, Single-Arm Trial of FT819 in Participants With Lupus Nephritis

for Lupus Nephritis

Sponsor: Fate Therapeutics

Sex: All·Age: 12 - 70

Code: NCT07570862·Phase 2

A Study to Evaluate the Safety, Tolerability, Cellular Kinetics, Pharmacodynamics, and Efficacy of P-CD19CD20-ALLO1 in Participants With Severe, Treatment-refractory Systemic Lupus Erythematosus (SLE)

for Systemic Lupus Erythematosus

2 sites incl. Birmingham

Sponsor: Genentech, Inc.

Sex: All·Age: 18 - 75

Code: NCT06984341·Phase 1

Crisaborole 2% Versus Tacrolimus 0.1% in Children With Mild to Moderate Atopic Dermatitis

for Atopic Dermatitis

Sponsor: Shalamar Institute of Health Sciences

Sex: All·Age: 2 - 18

Code: NCT07162896·Phase 3

Study of ADSTEM Injection for Patients With Moderate to Severe Subacute and Chronic Atopic Dermatitis

for Atopic Dermatitis

Sponsor: EHL Bio Co., Ltd.

Sex: All·Age: 19 - 70

Code: NCT07377838·Phase 3

Study of S-4321 in Participants With an Autoimmune or Immune-mediated Disease

for Autoimmune Diseases

Sponsor: Seismic Therapeutic AU Pty Ltd

Sex: All·Age: 18 - 75

Code: NCT07455578·Phase 1

Apply to this trial

Metformin Combined With Secukinumab for Moderate-to-Severe Plaque Psoriasis in Overweight or Obese Chinese Patients

for Psoriasis

Sponsor: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Sex: All·Age: 18 - 75

Code: NCT07485764·Phase 4

Proof of Concept Study Evaluating the Efficacy and Safety of ATH-063 Treatment in Patients With Relapsed/Refractory Moderately to Severely Active Ulcerative Colitis (UC)

for Ulcerative Colitis

2 sites incl. Miami

Sponsor: Athos Therapeutics Inc

Sex: All·Age: 18 - 75

Code: NCT07513181·Phase 2

Inflammation Digital Biomarkers Validation Study

for Psoriatic Arthritis

Sponsor: University of Oxford

Sex: All·Age: All ages

Code: NCT07594054

A Phase 2b Dose-Ranging Study to Evaluate the Efficacy and Safety of ENV-294 in Adults With Moderate-to-Severe Atopic Dermatitis

for Atopic Dermatitis

1 site in Encinitas

Sponsor: Enveda Therapeutics

Sex: All·Age: 18+

Code: NCT07643766·Phase 2

Intra-Articular Adelmidrol 2%/Hyaluronic Acid 1% With or Without m/umPEA, in Knee Pain Due to Joint Degeneration.

for Degenerative Joint Disease of Knee

Sponsor: Universita di Verona

Sex: All·Age: 40+

Code: NCT07680101

METabolic MODulation to Enhance Insulin Sensitivity and Mitochondrial Function in Type 1 Diabetes (MetMod-T1D)

for Type 1 Diabetes (T1D)

1 site in Seattle

Sponsor: University of Washington

Sex: All·Age: 18 - 69

Code: NCT07699380·Phase 2

Apply to this trial

Immun4Cure Cohort of Autoimmune Diseases

for Rheumatoid Arthritis

Sponsor: University Hospital, Montpellier

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07515638

Apply to this trial

The Impact of Dietary Salt on the Severity of Eczema

for Eczema

2 sites in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07447063·Phase 4

The Impact of Salt Intake on Sodium in the Skin and Inflammatory Skin Disease

for Atopic Dermatitis (Eczema)

2 sites in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07487831·Phase 4

A Clinical Trial on the Efficacy and Safety of TQH3906 in the Treatment of Systemic Lupus Erythematosus

for Systemic Lupus Erythematosus

Sponsor: Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Sex: All·Age: 18 - 74

Code: NCT07509892·Phase 2

Apply to this trial

Pentoxifylline Add-On Therapy for Mild-to-Moderate Plaque Psoriasis

for Psoriasis

Sponsor: Wasuchon Chaichan

Sex: All·Age: 18 - 65

Code: NCT07626788

Faecal Microbiota Transplantation in Patients With Refractory Rheumatoid Arthritis

for Rheumatoid Arthritis

Sponsor: Peking Union Medical College Hospital

Sex: All·Age: 18 - 65

Code: NCT07639177·Phase 2

A Study to Assess Concentration of TREMFYA in Breast Milk of Lactating Women Who Are Receiving TREMFYA Therapeutically

for Psoriasis

1 site in Chapel Hill

Sponsor: Janssen Research & Development, LLC

Sex: Female·Age: 18+

Code: NCT07654751·Phase 4

Biomarker Development for Autoimmune Disorders Involving the Kidneys

for Lupus Nephritis

Sponsor: Oslo University Hospital

Sex: All·Age: 18+

Code: NCT07666711

Apply to this trial

Sirolimus in Patients With Systemic Lupus Erythematosus-Associated Immune Thrombocytopenia

for Systemic Lupus Erythematosus

Sponsor: Chinese SLE Treatment And Research Group

Sex: All·Age: 18 - 65

Code: NCT07657793·Phase 2, Phase 3

Apply to this trial

Anifrolumab Pregnancy Study

for Systemic Lupus Erythematosus

1 site in Cary

Sponsor: AstraZeneca

Sex: Female·Age: 18 - 130

Code: NCT07049653

Apply to this trial

A Study to Evaluate D-2570 in Participants With Moderate to Severe Plaque Psoriasis

for Psoriasis

20 sites incl. Birmingham

Sponsor: InventisBio Co., Ltd

Sex: All·Age: 18 - 70

Code: NCT07489885·Phase 2

Apply to this trial

An Extension Study to Assess Long-Term Safety and Efficacy of Afimkibart in Participants With Rheumatoid Arthritis

for Rheumatoid Arthritis

1 site in Tomball

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT07620392·Phase 2

Apply to this trial

Transcutaneous Auricular Vagus Nerve Stimulation in Psoriatic Arthritis

for Psoriatic Arthritis

Sponsor: Marmara University

Sex: All·Age: 18 - 65

Code: NCT07653009

Apply to this trial

CAR-T Cells Targeting Autoimmune Diseases

for Autoimmune Diseases

Sponsor: Shenzhen Geno-Immune Medical Institute

Sex: All·Age: 18 - 75

Code: NCT05459870·Phase 1, Phase 2

Apply to this trial

A Randomized Controlled Trial Comparing the Effectiveness and Safety of Topical Tacrolimus 0.03% Versus Crisaborole 2% in Patients With Mild to Moderate Atopic Dermatitis Over 8 Weeks

for Atopic Dermatitis

Sponsor: Foundation University Islamabad

Sex: All·Age: 2 - 20

Code: NCT07519174

Tdose Binding and Tocilizumab

for Rheumatoid Arthritis

Sponsor: Centre Hospitalier Universitaire de Nice

Sex: All·Age: 18+

Code: NCT07582185·Phase 4

A Multicenter, Randomized, Double-blind, Vehicle Controlled Phase II Clinical Study to Evaluate the Efficacy and Safety of VC005 Gel in Adult Subjects With Mild to Moderate Atopic Dermatitis

for Atopic Dermatitis

Sponsor: Jiangsu vcare pharmaceutical technology co., LTD

Sex: All·Age: 18+

Code: NCT07598383·Phase 2

Apply to this trial

Safety and Efficacy of KSVCBD Injection in Autoimmune Diseases

for Autoimmune Diseases

Sponsor: Chinese PLA General Hospital

Sex: All·Age: 18 - 65

Code: NCT07613411·EARLY_Phase 1