Rheumatology Clinical Trials

Recruiting rheumatology studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat rheumatology. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting rheumatology studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting rheumatology trials

Within

Effect of S. Aureus Skin Decolonization on Disease Severity in Atopic Dermatitis Patients

for Atopic Dermatitis

1 site in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 6+

Code: NCT06397781·Phase 4

Autoimmune Disease Treatment With Mesenchymal Stem Cells (MSCs) and CAR-T Cells

for Autoimmune Diseases

Sponsor: Shenzhen Geno-Immune Medical Institute

Sex: All·Age: 18 - 75

Code: NCT06435897·Phase 1, Phase 2

CAR-T Cells Targeting Autoimmune Diseases

for Autoimmune Diseases

Sponsor: Shenzhen Geno-Immune Medical Institute

Sex: All·Age: 18 - 75

Code: NCT05459870·Phase 1, Phase 2

Determine the Dose-dependent Efficacy and Safety of EC-18 in Patients With Moderate to Severe Atopic Dermatitis

for Atopic Dermatitis

Sponsor: Enzychem Lifesciences Corporation

Sex: All·Age: 19 - 79

Code: NCT06487000·Phase 2

Safety and Preliminary Efficacy of HN2302 in Patients With Autoimmune Diseases

for Autoimmune Disease

Sponsor: Shenzhen MagicRNA Biotechnology Co., Ltd

Sex: All·Age: 18 - 69

Code: NCT07523282·Phase 1

Continued Access to Deucravacitinib for Adult SLE/SjD and Pediatric PsO/PsA Study Completers

for Systemic Lupus Erythematosus

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 4 - 75

Code: NCT07791199·Phase 3

Apremilast and Adalimumab in Psoriatic Arthritis Patients

for Psoriatic Arthritis

Sponsor: Tanta University

Sex: All·Age: 18 - 70

Code: NCT07398651

Safety and Tolerability of a Single Intravenous Infusion of BX-U001 in Refractory Rheumatoid Arthritis

for Rheumatoid Arthritis

Sponsor: Baylx Inc.

Sex: All·Age: 18 - 70

Code: NCT03828344·Phase 1

An AI-Based Erythema Measurement System for Psoriasis Lesions

for Psoriasis

Sponsor: Khon Kaen University

Sex: All·Age: 18 - 100

Code: NCT07494396

Assessing Psoriasis Treatment Outcomes

for Psoriasis

1 site in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT07391423

Serum Asprosin, Metabolic Syndrome, and Cardiometabolic Risk in Rheumatoid Arthritis

for Rheumatoid Arthritis

Sponsor: Assiut University

Sex: All·Age: 18+

Code: NCT07793747

Disease Impact and Its Correlation With Disease Activity in Psoriatic Arthritis

for Psoriatic Arthritis

Sponsor: Assiut University

Sex: All·Age: 18+

Code: NCT07793773

Subclinical Hypothyroidism and Disease Activity in Rheumatoid Arthritis

for Rheumatoid Arthritis

Sponsor: Assiut University

Sex: All·Age: 18+

Code: NCT07793786

Study to Characterise Pharmacokinetics (PK), Pharmacodynamics (PD), and Safety of Anifrolumab Administered Subcutaneously (SC) or Intravenously (IV)

for Systemic Lupus Erythematosus

Sponsor: AstraZeneca

Sex: All·Age: 18 - 70

Code: NCT07688980·Phase 1

A Study to Evaluate the Equivalence of IBI3027 and Dupilumab Injection in Participants With Moderate to Severe Atopic Dermatitis

for Atopic Dermatitis

Sponsor: Innovent Biologics (Suzhou) Co. Ltd.

Sex: All·Age: 18 - 75

Code: NCT07754786·Phase 3

A Study of Early Secukinumab Treatment in Moderate to Severe Hidradenitis Suppurativa Patients

for Hidradenitis Suppurativa

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07690319

A Study to Investigate the Efficacy and Safety Profile of GM-XANTHO [GM-XAN003] in Patients With Psoriasis

for Psoriasis

Sponsor: Xantho Biotechnology Co., LTD

Sex: All·Age: 20+

Code: NCT06620692·Phase 2

Saphnelo Use in Females of Child-bearing Potential

for Systemic Lupus Erythematosus

Sponsor: AstraZeneca

Sex: Female·Age: 15 - 50

Code: NCT07431775

Evaluation of Serum IL-41 Level in Patients With Ankylosing Spondylitis and Psoriatic Arthritis

for Ankylosing Spondylitis

Sponsor: Assiut University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07648836

Development and Evaluation of the Effectiveness of the SMART-HAND Protocol for Hand Rehabilitation in Patients With Rheumatoid Arthritis

for Rheumatoid Arthritis

Sponsor: Istanbul University - Cerrahpasa

Sex: All·Age: 18+

Code: NCT07754552

Capillary Sampling in Clinical Populations Undergoing Monitoring

for Chronic Kidney Disease

Sponsor: University of Edinburgh

Sex: All·Age: 6+

Code: NCT07802665

A Randomised Controlled Trial of ePROM-Guided Flexible Scheduling in Dermatology

for Chronic Dermatological Conditions

Sponsor: National University Hospital, Singapore

Sex: All·Age: 16+

Code: NCT07481019

Disulfiram in Rheumatoid Arthritis

for Rheumatoid Arthritis

1 site in Oklahoma City

Sponsor: University of Oklahoma

Sex: All·Age: 18 - 75

Code: NCT07534332·Phase 2

Effectiveness of Upadacitinib and Biologics for the Achievement of Minimal Disease Activity in Adults With Moderate-to-Severe Atopic Dermatitis (RAMpUp)

for Atopic Dermatitis

Sponsor: AbbVie

Sex: All·Age: 18 - 64

Code: NCT07741838

Inflammation, Autoimmunity and Healthy Ageing in Menopause Transition. An Observational, Cross-sectional Study

for Autoimmune Diseases

Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia

Sex: Female·Age: 40 - 60

Code: NCT07784400

Mediterranean Dietary Intervention for HS

for Hidradenitis Suppurativa

1 site in Chapel Hill

Sponsor: University of North Carolina, Chapel Hill

Sex: All·Age: 18+

Code: NCT07800416

Randomized, Double-blind, Placebo-controlled Study of Nemolizumab in Chinese Subjects With Moderate-to-severe Atopic Dermatitis

for Atopic Dermatitis

Sponsor: Galderma R&D

Sex: All·Age: 12+

Code: NCT07762833·Phase 3

A Real-world Study of Patients With Hidradenitis Suppurativa and High Cardiovascular Risk or Established Coronary Plaque Treated With Secukinumab

for Hidradenitis Suppurativa

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 75

Code: NCT07454889

A Trial in Healthy Adult Participants and Adults With Autoimmune Disease to Test How HBM7020 is Tolerated and Absorbed in the Body

for Rheumatoid Arthritis

Sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc.

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT07649265·Phase 1

A Study of Guselkumab Given After Ustekinumab in Participants With Moderate to Severe Psoriasis in Routine Clinical Practice

for Psoriasis

Sponsor: Janssen-Cilag Kft.

Sex: All·Age: 18+

Code: NCT07746583

Apply to this trial

A Study to Learn About a Medicine Called PF-08154225 in Participants With Autoimmune Diseases

for Systemic Lupus Erythematosus

Sponsor: Pfizer

Sex: All·Age: 18 - 70

Code: NCT07782450·Phase 1, Phase 2

Deciphering the Genetic Architecture of Autoimmune Diseases

for Autoimmune Diseases

Sponsor: National Human Genome Research Institute (NHGRI)

Sex: All·Age: 18 - 115

Code: NCT06948110

Apply to this trial

Evaluating the Safety and Tolerability of Baricitinib in Patients With Job Syndrome With Lupus-Like Disease and/or Atopic Dermatitis

for Hyper IgE Syndrome From STAT3 Mutation

1 site in Bethesda

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 12 - 120

Code: NCT07262983·Phase 1

Apply to this trial

Phase 1 Study of QX-4533 in Healthy Volunteers and Patients With Moderate-to-Severe Atopic Dermatitis

for Atopic Dermatitis

Sponsor: QuantX Biosciences, Inc.

Sex: All·Age: 18 Months - 65·Accepts healthy volunteers

Code: NCT07800104·Phase 1

Safety and Efficacy of ONT01 in Lupus

for Lupus Nephritis (LN)

1 site in New York

Sponsor: Hospital for Special Surgery, New York

Sex: All·Age: 18+

Code: NCT07107659·EARLY_Phase 1

Apply to this trial

Retention of Vernix Caseosa in Newborns for Primary Prevention of Atopic Dermatitis

for Atopic Dermatitis

Sponsor: Pontificia Universidad Catolica de Chile

Sex: All·Age: 0 Days+·Accepts healthy volunteers

Code: NCT07333378

A Study of ATG-201 in Adult Participants With Autoimmune Diseases

for Systemic Lupus Erythematosus

Sponsor: Antengene Biologics Limited

Sex: All·Age: 18+

Code: NCT07732309·Phase 1

Inflammatory Disease Biobank for Immunophenotyping and Cardiovascular Research

for Pericarditis

Sponsor: Assistance Publique - Hôpitaux de Paris

Sex: All·Age: 18+

Code: NCT07737470

Efficacy and Safety of Telitacicept in the Treatment of Refractory Rheumatoid Arthritis

for Difficult-to-treat Rheumatoid Arthritis

Sponsor: Peking University People's Hospital

Sex: All·Age: 18+

Code: NCT07796516·Phase 2

Apply to this trial

The ROOT Study: Scaling the 'Standard of Care Plus' Obstetric Nutrition Model to Optimize Maternal and Infant Health

for Preterm Birth

Sponsor: GrowBaby Life Project

Sex: Female·Age: 18+

Code: NCT07559773

Opzelura Experience Study

for Atopic Dermatitis

1 site in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 2+

Code: NCT07661979·Phase 4

Efficacy and Tolerability of a Probiotic Ointment

for Atopic Dermatitis

Sponsor: BioGaia AB

Sex: All·Age: 6 Months - 15

Code: NCT07701447

A Clinical Trial of TQH3906 Capsules in Adult Patients With Moderate to Severe Plaque Psoriasis

for Psoriasis

Sponsor: Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd.

Sex: All·Age: 18 - 75

Code: NCT07724366·Phase 3

SNC116 Therapy for Refractory Systemic Lupus Erythematosus

for Systemic Lupus Erythematosus

Sponsor: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

Sex: All·Age: 18 - 65

Code: NCT07748156·EARLY_Phase 1

Study of PTC844 in Participants With Active Rheumatoid Arthritis

for Rheumatoid Arthritis

Sponsor: PTC Therapeutics

Sex: All·Age: 18 - 70

Code: NCT07779616·Phase 2

A Study Evaluating TRIV-573 in Atopic Dermatitis

for Atopic Dermatitis

Sponsor: Triveni Bio

Sex: All·Age: 18 - 75

Code: NCT07782333·Phase 2

A Study to Test CRT-402 in Refractory Autoimmune Disease

for Autoimmune Diseases

Sponsor: Myeloid Therapeutics

Sex: All·Age: 18+

Code: NCT07778446·Phase 1, Phase 2

SII and SIRI as Prognostic Biomarkers in Lupus Nephritis

for Lupus Nephritis

Sponsor: Assiut University

Sex: All·Age: 18 - 70

Code: NCT07780045

A Study to Learn About the Study Medicine Called Tilrekimig in People With Moderate-to Severe Eczema

for Atopic Dermatitis

1 site in Tulsa

Sponsor: Pfizer

Sex: All·Age: 12+

Code: NCT07783425·Phase 3

Combined Fractional CO₂ Laser and Topical Corticosteroid Versus Topical Corticosteroid Only in the Treatment of Palmoplantar Psoriasis

for Psoriasis

Sponsor: Cairo University

Sex: All·Age: 18 - 60

Code: NCT07713212·Phase 4

Digital Mindfulness Meditation in Adolescents With Atopic Dermatitis

for Atopic Dermatitis

2 sites in New York

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 12 - 17

Code: NCT07746427

Apply to this trial

A Study to Learn About the Study Medicine Called Tilrekimig in People With Moderate-to-Severe Eczema

for Atopic Dermatitis

Sponsor: Pfizer

Sex: All·Age: 12+

Code: NCT07765888·Phase 3

A Phase 1 Study to Evaluate the Safety and Effects of a Single Dose of HCXT-2001 Tablets and HCXT-2001 Tablets(A) in Healthy Adults.

for Psoriasis

Sponsor: Shanghai Peptidstar Therapeutics Limited

Sex: All·Age: 18 - 45·Accepts healthy volunteers

Code: NCT07792928·Phase 1

A Study of QLS2404 Injection in Healthy Participants and Participants With Rheumatic Autoimmune Diseases

for Systemic Lupus Erythematosus

Sponsor: Qilu Pharmaceutical Co., Ltd.

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07751315·Phase 1

Music-4-MS to Improve Cognition in People Living With Multiple Sclerosis: A Feasibility Study

for Multiple Sclerosis

1 site in Austin

Sponsor: University of Texas at Austin

Sex: All·Age: 18 - 80

Code: NCT07759115

Apply to this trial

A Study to Assess Concentration of TREMFYA in Breast Milk of Lactating Women Who Are Receiving TREMFYA Therapeutically

for Psoriasis

1 site in Chapel Hill

Sponsor: Janssen Research & Development, LLC

Sex: Female·Age: 18+

Code: NCT07654751·Phase 4

Apply to this trial

Phase II Clinical Trial of SHR-1139 Injection in Patients With Psoriasis

for Psoriasis

Sponsor: Guangdong Hengrui Pharmaceutical Co., Ltd

Sex: All·Age: 18+

Code: NCT07719530·Phase 2

Apply to this trial

Utilization of a Microdevice for Psoriasis and Atopic Dermatitis

for Psoriasis

1 site in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT07352566·Phase 4

Nailfold Capillaroscopic Changes in Psoriasis

for Psoriasis

Sponsor: Al-Azhar University

Sex: All·Age: All ages

Code: NCT07693595

Apply to this trial

Azithromycin in Atopic Dermatitis

for Atopic Dermatitis

Sponsor: Cairo University

Sex: All·Age: 3 - 12

Code: NCT07713186·Phase 4

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Rheumatology clinical trials — common questions

Are rheumatology clinical trials free to join?

Yes. Participating in a rheumatology clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a rheumatology clinical trial?

Each rheumatology study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a rheumatology trial near me?

Use the location controls above. We'll show recruiting rheumatology trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many rheumatology trials are recruiting right now?

We're currently tracking roughly 268 recruiting rheumatology trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Rheumatology trials by city

Birmingham, AL San Francisco, CA Boston, MA Chicago, IL Sacramento, CA Ann Arbor, MI Beverly Hills, CA Cleveland, OH Columbus, OH Fountain Valley, CA La Jolla, CA Los Angeles, CA

Conditions in this area

Rheumatoid arthritis Psoriatic arthritis Lupus (SLE)Psoriasis Atopic dermatitis / eczema Hidradenitis suppurativa Autoimmune diseases (general)