Pain and Autonomic Symptoms in Parkinson's Disease and Atypical Parkinsonisms

Sponsor
Istituti Clinici Scientifici Maugeri SpA
Study ID
NCT05748028
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Rehabilitation — OTHER
    All patients included in the study will undergo a basic evaluation with a neurological examination, a rehabilitation program to improve strength, coordination, balance, endurance, and the ability to perform activities of daily life.
  • Administration of Clinical scales — OTHER
    All patients included in the study will be evaluated by clinical scales assessing the disease stage, clinical severity, freezing, motor and non-motor impairment, cognitive impairment, depression, quality of life, autonomic dysfunction, pain.

Study Details

The goal of this observational study is to learn about the impact of the different types of pain and of the domains involved in the autonomic disorders of inpatients and outpatients diagnosed with Parkinson disease (PD) and multiple system atrophy (MSA) admitted to Istituti Clinici Scientifici Maugeri Centers. The main aims are: Evaluate the prevalence of pain and characterize it in Parkinson's disease and atypical parkinsonisms (MSA) Evaluate the effect of rehabilitation on pain and autonomic symptoms Evaluate the prevalence of autonomic symptoms in Parkinson's disease and atypical parkinsonisms (MSA) Assess the impact of pain and autonomic symptoms on quality of life. Participants will perform neurological examination, rehabilitation program and clinical scales. Researchers will compare the two groups of patients (PD and MSA) and the effect of the rehabilitation on pain, autonomic symptoms and quality of life.

Key Dates

First listed
Feb 28, 2023
Start date
Jun 15, 2019
Status verified
Apr 2026
Primary completion
Sep 30, 2026
Completion
Dec 30, 2026

Study Design

Enrollment
280 participants (estimated)

Arms

  • Arm: Parkinson Disease
    Patients affected by Parkinson's disease admitted for rehabilitation in Maugeri Clinical Scientific Institutes
  • Arm: Multiple System Atrophy
    Patients affected by Multiple System Atrophy admitted for rehabilitation in Maugeri Clinical Scientific Institutes

Primary Outcome Measure

Prevalence and Characterization of Pain [ Time Frame: At the recruitment ]

Central Contacts

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