Parkinson's disease Clinical Trials

Recruiting parkinson's disease studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat parkinson's disease. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting parkinson's disease studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting parkinson's disease trials

Within

Double-Blind Clinical Trial of Subthalamic Nucleus Deep Brain Stimulation in Early-Stage Parkinson's Disease

for Parkinson Disease

Sponsor: Mallory Hacker

Sex: All·Age: 50 - 75

Code: NCT06008717

Gastrointestinal Dopamine Decarboxylase and Levodopa Pharmacokinetics

for Parkinson's Disease

1 site in Boston

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: All ages

Code: NCT07793461·Phase 4

A Study of AB-1005 Gene Therapy in Japanese Adults With Moderate Parkinson's Disease (J-REGENERATE-PD)

for Parkinson Disease

Sponsor: Bayer

Sex: All·Age: 45 - 75

Code: NCT07566429·Phase 2

Low Intensity Focused Ultrasound for Parkinson's Disease

for Parkinson Disease

Sponsor: Ali Rezai

Sex: All·Age: 45 - 80

Code: NCT06763692

A Behavioral Digital Intervention For Parkinson's Disease

for Parkinson Disease

Sponsor: Egas Moniz - Cooperativa de Ensino Superior, CRL

Sex: All·Age: 18+

Code: NCT07705620

The Effects of Ischemic Conditioning in Individuals With Parkinson's Disease

for Parkinson Disease

Sponsor: Hospital Israelita Albert Einstein

Sex: All·Age: 40 - 90

Code: NCT06293118

Behavioral and/or Mirabegron to Treat Urinary Symptoms in Parkinson Disease

for Overactive Bladder

3 sites incl. Decatur

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT07187466·Phase 4

Brain Dopamine Biomarker

for Parkinson Disease

Sponsor: University of South Florida

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07748715

Smartshoes for Freezing of Gait in Parkinson's Disease

for Parkinson Disease

1 site in Palo Alto

Sponsor: Stanford University

Sex: All·Age: 40 - 80·Accepts healthy volunteers

Code: NCT07001072

Study of Transanal Irrigation vs Standard Care for Constipation, Gut Microbiota, and Motor Disorders in Parkinson's Disease

for Parkinson Disease

Sponsor: University Hospital of Ferrara

Sex: All·Age: 18+

Code: NCT07716553

Unilateral and Staged Bilateral Pallidothalamic Tractotomy Using Exablate MRgFUS in Advanced Parkinson's Disease.

for Parkinson Disease

Sponsor: InSightec

Sex: All·Age: 30+

Code: NCT07764874

Study to Test Effects and Safety of RO7568282 in Early Parkinson's Disease

for Parkinson's Disease

Sponsor: Hoffmann-La Roche

Sex: All·Age: 40 - 85

Code: NCT07781644·Phase 1, Phase 2

Decoding the Neural Mechanisms Underlying Postural Instability and Gait Dysfunction in Parkinson's Disease

for Parkinson Disease

1 site in Cleveland

Sponsor: The Cleveland Clinic

Sex: All·Age: 18+

Code: NCT07748962

Accelerated rTMS for Apathy in Parkinson's Disease

for Parkinson Disease

1 site in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 45 - 85

Code: NCT07399496

Apply to this trial

Remote Monitoring in Progressive Supranuclear Palsy (PSP)

for Progressive Supranuclear Palsy

2 sites incl. Baltimore

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 89

Code: NCT04753320

Function-based Accelerated Stimulation Therapy (FAST-therapy) for Freezing of Gait (FOG) After Parkinson's Disease (PD)

for Parkinson Disease

1 site in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 45 - 90

Code: NCT05509842

Mild Cognitive Impairment Community Screening and Early Intervention Via Stem Cell Therapy and Wearable Brain Computer Interface Device.

for Mild Cognitive Impairment (MCI)

1 site in Palisades Park

Sponsor: Noah Tech, Corp.

Sex: All·Age: 55+·Accepts healthy volunteers

Code: NCT07214974·EARLY_Phase 1

Gamification and Physical Activity in PD

for Parkinson Disease

1 site in Philadelphia

Sponsor: VA Office of Research and Development

Sex: All·Age: 50 - 89

Code: NCT07286994

Terazosin And Metabolic Engagement in Parkinson's Disease

for Parkinson's Disease

Sponsor: Nandakumar Narayanan

Sex: All·Age: 40 - 90

Code: NCT07288450·Phase 1, Phase 2

Prevention of Medical, Social, and Psychosocial Risks Following a Parkinson's Disease Diagnosis: A Pilot Study

for Parkinson Disease

Sponsor: University Hospital, Toulouse

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07578272

Fecal Microbiota Transplantation in Parkinson's Disease.

for Parkinson's Disease

Sponsor: Chang Gung Memorial Hospital

Sex: All·Age: 18+

Code: NCT07597421

Segmental Laser Acupuncture for Constipation and Sleep in Patients With Parkinson's Disease

for Parkinson's Disease

Sponsor: China Medical University Hospital

Sex: All·Age: 50+

Code: NCT07790094

Effects of Lemborexant on Motor-sleep Comorbidity in Parkinson's Disease

for Parkinson's Disease

Sponsor: YangPan

Sex: All·Age: 50+

Code: NCT07384429·Phase 4

Effects of Targeted Temporal Interference Stimulation of Cerebellar Nuclei on Tremor and Gait Disturbance in Parkinson's Disease Patients

for Parkinson's Disease

Sponsor: YangPan

Sex: All·Age: 50+

Code: NCT07384442

Cross-System Effects of Acute Intermittent Hypercapnia-Based Interventions in PD

for Parkinson Disease

2 sites in Gainesville

Sponsor: University of Florida

Sex: All·Age: 40 - 75

Code: NCT07674264

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NAD Supplementation in Parkinson's Disease

for Parkinson's Disease

1 site in Oklahoma City

Sponsor: University of Oklahoma

Sex: All·Age: 55 - 85

Code: NCT07703137

Phase I/II Clinical Trial of UX-DA003 Injection for the Treatment of Patients With Parkinson's Disease

for Parkinson's Disease

Sponsor: Shanghai UniXell Biotechnology Co., Ltd

Sex: All·Age: 30 - 75

Code: NCT07733349·Phase 1, Phase 2

Superior Parietal iTBS for PD-MCI

for Parkinson Disease

1 site in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 50 - 85

Code: NCT07701785

Apply to this trial

Fecal MicrobiotaTransplant for the Treatment of Parkinson's Disease

for Parkinson Disease

1 site in Ventura

Sponsor: ProgenaBiome

Sex: All·Age: 18 - 85

Code: NCT06647277·Phase 1

Characterization of the Involvement of the Subthalamic Nucleus During Wakefulness and Sleep in Parkinson's Disease: Contribution of Deep Brain Stimulation

for Parkinson Disease

Sponsor: University Hospital, Grenoble

Sex: All·Age: 18+

Code: NCT07637955

An Unblinded, Single Arm, Pilot Observational Study to Test the Safety, Tolerability, Immunogenicity and the Biological Effects of TRB-001 Vaccination in Individuals Who Have Previously Undergone aSyn Immunotherapy

for Parkinson's Disease

Sponsor: Tridem Bioscience FlexCo

Sex: All·Age: 18+

Code: NCT07777484·Phase 1

Apply to this trial

A US Study That Observes How Parkinson's Disease Changes Over Time in Patients Who Still Have Movement Symptoms Despite Taking Parkinson's Medications

for Parkinson's Disease

26 sites incl. Phoenix

Sponsor: Bayer

Sex: All·Age: 45 - 75

Code: NCT07330258

Apply to this trial

Neural Mechanisms of Aerobic Exercise Benefits in PD With DBS

for Parkinson's Disease

1 site in Cleveland

Sponsor: The Cleveland Clinic

Sex: All·Age: 18+

Code: NCT07442747·Phase 2

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Temporal Interference Noninvasive Deep Brain Stimulation for Idiopathic Parkinson's Disease and Parkinsonian Syndromes: Effects and Target Exploration

for Parkinson's Disease

Sponsor: Ruijin Hospital

Sex: All·Age: 40 - 80

Code: NCT07698236

Efficacy of a Prediction Model-based Algorithm to PREVENT Drug-induced Impulse Control Disorders in Parkinson's Disease

for Parkinson Disease

Sponsor: Assistance Publique - Hôpitaux de Paris

Sex: All·Age: 18+

Code: NCT07505394

HF-rTMS Primed Balance Training on Corticomotor Excitability, Balance, and Gait in Parkinson's

for Parkinson's Disease

Sponsor: Chung Shan Medical University

Sex: All·Age: 40 - 80

Code: NCT07653256

The Efficacy and Safety of Transcutaneous Auricular Vagus Nerve Stimulation for Depression in PD

for Parkinson Disease

Sponsor: The First Affiliated Hospital with Nanjing Medical University

Sex: All·Age: 40 - 80·Accepts healthy volunteers

Code: NCT07679529

Low-dose Carbon Monoxide (HBI-002) Trial to Evaluate Safety, Tolerability, PK, and Biomarkers in Parkinson's Disease

for Parkinson Disease

5 sites incl. Fountain Valley

Sponsor: Hillhurst Biopharmaceuticals, Inc.

Sex: All·Age: 40 - 80

Code: NCT07005180·Phase 2

Apply to this trial

A Trial Investigating Lu AF28996 in Adults With Parkinson's Disease Who Have Motor Fluctuations

for Parkinson's Disease

Sponsor: H. Lundbeck A/S

Sex: All·Age: 40 - 85

Code: NCT07514858·Phase 2

Motor and Cognitive Telerehabilitation in a Virtual Environment in Patients With Post-stroke Sequelae and Parkinson's Disease

for Ictus

Sponsor: Azienda Usl di Bologna

Sex: All·Age: 18+

Code: NCT07582497

Evaluation of the Impact of Virtual Park on Training Motivation in Adult Patients

for Post-stroke

Sponsor: Marta Mondellini

Sex: All·Age: 18+

Code: NCT07616050

Evaluation of a Soft Elbow Exoskeleton and a Haptic Armband in Post-stroke and Parkinson's Disease Patients

for Stroke

Sponsor: IRCCS San Raffaele Roma

Sex: All·Age: 18+

Code: NCT07637123

Monoamine Oxidase B PET/CT in Various MAO-B-Related Disease

for Parkinson Disease

Sponsor: Tianjin Medical University

Sex: All·Age: 18 - 90·Accepts healthy volunteers

Code: NCT07685873

Apply to this trial

Telerehabilitation Versus Face-to-Face LSVT BIG in Individuals With Parkinson Disease

for PARKINSON DISEASE (Disorder)

Sponsor: Bezmialem Vakif University

Sex: All·Age: All ages

Code: NCT07630792

Upper Extremity Skills, Trunk Control, and Body Awareness in Parkinson's Disease

for Parkinson Disease

Sponsor: Baskent University

Sex: All·Age: 50 - 80·Accepts healthy volunteers

Code: NCT07639463

Deep Brain Stimulation in Parkinson's Disease: Motor and Functional Outcomes

for Parkinson Disease

Sponsor: Federal University of Minas Gerais

Sex: All·Age: All ages

Code: NCT07567599

Artificial Intelligence-assisted MDS-UPDRS Assessment for Parkinson's Disease

for Parkinson Disease

Sponsor: Hong Kong University of Science and Technology

Sex: All·Age: 18 - 95

Code: NCT07381751

Apply to this trial

At-home taVNS for Neurorehabilitation in Parkinson's Disease

for Parkinson's Disease

1 site in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 40 - 85

Code: NCT07536022

Apply to this trial

RESvEraTrol in Parkinson's Disease (RESET)

for Parkinson's Disease

Sponsor: Georgetown University

Sex: All·Age: 55 - 85

Code: NCT07592767·Phase 2

Depression, Anxiety and Sleep in Parkinson's Disease

for Parkinson's Disease

Sponsor: Sohag University

Sex: All·Age: 50+

Code: NCT07622303

Impact of Diet on the Microbiome-Immune-Brain Axis in Parkinson's Disease

for Parkinson Disease

Sponsor: University of Kiel

Sex: All·Age: 50 - 80

Code: NCT06463769

Amyloid Monoclonal Antibody Treatment in PD Patients With Coexistent AD Pathology

for Parkinson Disease

Sponsor: Yonsei University

Sex: All·Age: 50 - 90

Code: NCT07544953

A Study to Evaluate the Efficacy and Safety of Monosialotetrahexosylganglioside Sodium Injection in Parkinson's Disease Participants With Motor Fluctuations

for Parkinson's Disease

Sponsor: Qilu Pharmaceutical Co., Ltd.

Sex: All·Age: 30+

Code: NCT07585565·Phase 2

Effectiveness of Virtual Reality in Parkinson's Disease: Effects on Balance, Fall Risk, and Exercise Capacity.

for Parkinson Disease

Sponsor: University of Valencia

Sex: All·Age: 55 - 75

Code: NCT07251231

Efficacy, Safety, Tolerability, and Biomarker Effects of GT-02287 in Early Parkinson's Disease

for Parkinson Disease

Sponsor: Gain Therapeutics, Inc.

Sex: All·Age: 30 - 85

Code: NCT07280299·Phase 2

Phase 1 Clinical Trial to Evaluate the Safety, Efficacy, and Pharmacokinetics of IPS101A in Parkinson's Disease Patients

for Parkinson Disease

Sponsor: Innopeutics Corporation

Sex: All·Age: 50 - 80

Code: NCT07371338·Phase 1

Apply to this trial

A Long-Term Follow-up Study of the Severe Parkinson's Disease Patients Administered the IPS101A Gene Therapy Product.

for Parkinson Disease

Sponsor: Innopeutics Corporation

Sex: All·Age: 50 - 80

Code: NCT07629115

Apply to this trial

A Trial of Lu AF28996 in Participants With Parkinson's Disease (PD)

for Parkinson Disease

Sponsor: H. Lundbeck A/S

Sex: All·Age: 35 - 85

Code: NCT07513441·Phase 1

Apply to this trial

"Turkish Validity and Reliability of the Heat Sensitivity Scale for Individuals With Parkinson's Disease"

for Parkinson Disease

Sponsor: Acibadem University

Sex: All·Age: 40 - 85

Code: NCT07710625

Apply to this trial

A Pilot Study of In-lab Dynamic Standing in Parkinson's Disease

for Parkinson Disease

1 site in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 50+

Code: NCT07543861·Phase 1

Apply to this trial

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Parkinson's disease clinical trials — common questions

Are parkinson's disease clinical trials free to join?

Yes. Participating in a parkinson's disease clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a parkinson's disease clinical trial?

Each parkinson's disease study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a parkinson's disease trial near me?

Use the location controls above. We'll show recruiting parkinson's disease trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many parkinson's disease trials are recruiting right now?

We're currently tracking roughly 221 recruiting parkinson's disease trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Parkinson's disease trials by city

Birmingham, AL Boston, MA Cleveland, OH Ann Arbor, MI San Francisco, CA Stanford, CA Aurora, CO Gainesville, FL Los Angeles, CA Portland, OR Newark, DE Chicago, IL

Related specialties

Neurology Brain disorders