Auditory Functions in Patients With Multiple Sclerosis

Sponsor
University of Catania
Study ID
NCT06164483
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
20 Years - 40 Years
Healthy Volunteers
Accepted

Interventions

  • Auditory test — DIAGNOSTIC_TEST
    The patients will perform: Pure Tone Auditory test + Tympanometry and Stapedial Reflex * Speech Perception test * In case of tinnitus: tinnitus questionnaire and acuphenometry * DPOAEs * ABR
  • CSF sampling — OTHER
    Cerebrospinal Fluid will be collected by lumbar puncture and analyzed

Study Details

The study will analyze the auditory functions of patients with Multiple Sclerosis using auditory tests like pure tone auditory test, speech perception test, Auditory Brain Response (ABR) and Distortion Product Otoacustic Emission (DPOAE). CSF will be collected by lumbar puncture and analyzed looking for inflammatory markers. The results of DPOAE and CSF will be correlated to identify statistically significant correlation.

Key Dates

First listed
Dec 11, 2023
Start date
May 11, 2026
Status verified
May 2026
Primary completion
Dec 30, 2027
Completion
Dec 30, 2028

Study Design

Enrollment
30 participants (estimated)

Arms

  • Arm: Control
    Healthy patients between 20 and 40 years
  • Arm: MS group
    Patient with Relapsing Remitting MS age between 20 and 40 years

Primary Outcome Measure

Auditory functions and correlation with CSF findings [ Time Frame: 12 months ]

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