Long Term Follow-up Grafted Huntington's Disease Patients

Sponsor
Assistance Publique - Hôpitaux de Paris
Study ID
NCT06194006
Status
Not Yet Recruiting

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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Follow-up — OTHER
    Follow-up grafted patients as long as their condition allows

Study Details

Long-term follow-up of Huntington's disease patients treated with intrastriatal allografts is essential to assess the benefit/risk ratio of grafts as well as their effectiveness. Indeed, some patients are likely to develop adverse effects and the impact of alloimmunisation phenomena remains to be explored.

Key Dates

First listed
Jan 8, 2024
Start date
Jan 1, 2024
Status verified
May 2023
Primary completion
Jan 1, 2034
Completion
Jan 1, 2034

Study Design

Enrollment
39 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER

Arms

  • Other: Long term follow-up
    * Formalized and standardized follow-up * Retrospective data collection * Biological collections * Biological collections's centralisation

Primary Outcome Measure

Progression of the Unified Huntington's Disease Rating Scale (UHDRS) motor score [ Time Frame: From the end of participation at MIGHD's study until the death from any cause or assessed up to 10 years after consentement signed ]

Central Contacts

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