Huntington disease Clinical Trials

Recruiting huntington disease studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat huntington disease. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting huntington disease studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting huntington disease trials

Within

Pridopidine Phase 3 Study in Huntington's Disease

for Huntington Disease

Sponsor: Prilenia

Sex: All·Age: 23 - 65

Code: NCT07609108·Phase 3

Mass Balance Study of [14C] LPM3770164 in Healthy Participants

for Huntington Disease

Sponsor: Luye Pharma Group Ltd.

Sex: Male·Age: 18 - 45·Accepts healthy volunteers

Code: NCT07516899·Phase 1

Optimizing Parameters of Low-Intensity Focused Ultrasound for Pallidal Modulation in Huntington's Disease

for Huntington Disease

Sponsor: First Affiliated Hospital of Fujian Medical University

Sex: All·Age: 18 - 75

Code: NCT07513844

Apply to this trial

Safety and Tolerability Study of Human Neural Stem Cells for Huntington's Disease

for Huntington Disease

1 site in Irvine

Sponsor: Leslie Thompson

Sex: All·Age: 18 - 65

Code: NCT07451613·Phase 1, Phase 2

Apply to this trial

Autobiographical Memory, Future Thought, and Eye Movements in Huntington's Disease

for Huntington Disease

Sponsor: University Hospital, Angers

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07409597

A Study to Investigate the Efficacy, Safety and Tolerability of Votoplam in Participants With Huntington's Disease

for Huntington Disease

21 sites incl. La Jolla

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 21 - 70

Code: NCT07326709·Phase 3

Apply to this trial

iMagemHTT-009- FIH Evaluation of Novel Mutant Huntingtin PET Radioligand [11C]CHDI-00491009

for Huntington Disease

Sponsor: CHDI Foundation, Inc.

Sex: All·Age: 18 - 64·Accepts healthy volunteers

Code: NCT06634628·EARLY_Phase 1

Apply to this trial

Multi-Modal Digital Monitoring of Disease Symptoms Huntington's Disease

for Huntington Disease

2 sites incl. Rochester

Sponsor: BioSensics

Sex: All·Age: 25 - 65·Accepts healthy volunteers

Code: NCT07315984

Study to Evaluate the Pharmacodynamics, Safety and Efficacy of SKY-0515 in Participants With Huntington's Disease

for Huntington Disease

Sponsor: Skyhawk Therapeutics, Inc.

Sex: All·Age: 25+

Code: NCT07378644·Phase 2, Phase 3

Apply to this trial

Evaluation of Three Tests to Assess Social Cognition in Huntington Disease

for Huntington Disease

Sponsor: Region Skane

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT07253038

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Home-based TDCS (Transcranial Direct Current Stimulation) for Cognitive and Behavioral Symptoms in Huntington's Disease

for Huntington Disease

1 site in San Antonio

Sponsor: The University of Texas Health Science Center at San Antonio

Sex: All·Age: 18 - 85

Code: NCT06843252

Apply to this trial

Hinting Task for Huntington's Disease

for Huntington Disease

Sponsor: University Medical Center Groningen

Sex: All·Age: 18 - 74

Code: NCT06774443

Apply to this trial

Transcranial Static Magnetic Stimulation (tSMS) in Huntington's Disease (HD)

for Huntington Disease

Sponsor: Neuromed IRCCS

Sex: All·Age: All ages

Code: NCT06976983

Gut Microbiomes in HD

for Huntington Disease

1 site in Orlando

Sponsor: University of Central Florida

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06448546

Apply to this trial

Cognitive Assessment Tools for Huntington's Disease.

for Huntington Disease

1 site in Columbus

Sponsor: Ohio State University

Sex: All·Age: 30 - 65

Code: NCT06546488

Apply to this trial

Digital Measures for Clinical Trial Endpoints in Huntington's Disease

for Huntington Disease

1 site in Rochester

Sponsor: University of Rochester

Sex: All·Age: 25 - 65·Accepts healthy volunteers

Code: NCT07010705

Apply to this trial

The NAD-HD Study: A Study to Investigate Efficacy and Safety of Nicotinamide Riboside Compared With Placebo in Huntington's Disease

for Huntington Disease

Sponsor: Oslo University Hospital

Sex: All·Age: 18 - 80

Code: NCT06853743·Phase 2

Apply to this trial

A Randomized Study of SPK-10001 Gene Therapy in Participants With Huntington's Disease

for Huntington Disease

5 sites incl. Boston

Sponsor: Hoffmann-La Roche

Sex: All·Age: 25 - 65

Code: NCT06826612·Phase 1, Phase 2

Apply to this trial

Early Biomarkers in Premanifest Huntington's Disease Gene Carriers: a Pilot Study

for Huntington Disease

Sponsor: University Hospital, Grenoble

Sex: All·Age: 18 - 70·Accepts healthy volunteers

Code: NCT06626308

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Huntington's Disease and Pain

for Huntington Disease

Sponsor: Leiden University Medical Center

Sex: All·Age: 21+

Code: NCT06693466

Comparison Between [11C]UCB-J and [18F]SynVest-1 PET in HD.

for Huntington Disease

Sponsor: Universitaire Ziekenhuizen KU Leuven

Sex: All·Age: 20 - 75·Accepts healthy volunteers

Code: NCT05360082

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Development of Non-Invasive Prenatal Diagnosis for Single Gene Disorders

for Invasive PreNatal Diagnosis in a Context of Family History of Single-gene Disorders, Including

Sponsor: Assistance Publique - Hôpitaux de Paris

Sex: Female·Age: 18+

Code: NCT06147414

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Study to Evaluate Music Therapy on Irritability and Impulsivity in Patients With Huntington's Disease (MUSIC-HD)

for Huntington Disease

Sponsor: Poitiers University Hospital

Sex: All·Age: 18+

Code: NCT06414967

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Gene Therapy Development and Validation for Huntington's Disease Fibro TG-HD

for Huntington Disease

Sponsor: University Hospital, Angers

Sex: All·Age: 18 - 70

Code: NCT06444217

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Frequency of Selected Single Nucleotide Polymorphisms in Huntington Disease Gene Expansion Carriers

for Huntington Disease

1 site in Nashville

Sponsor: Hoffmann-La Roche

Sex: All·Age: 25 - 60

Code: NCT06667414

Apply to this trial

Longitudinal Endpoint Assessment of Disease Burden in HD

for Huntington Disease

1 site in Rochester

Sponsor: Huntington Study Group

Sex: All·Age: 18+

Code: NCT06475898

Apply to this trial

FLOWER: Following Longitudinal Outcomes With Epidemiology for Rare Diseases

for Alpha-Thalassemia

1 site in Los Altos

Sponsor: xCures

Sex: All·Age: All ages

Code: NCT06539169

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A Randomised Controlled Trial, Of N-Acetyl Cysteine (NAC), for Premanifest Huntingtin Gene Expansion Carriers

for Huntington Disease

Sponsor: Western Sydney Local Health District

Sex: All·Age: 18+

Code: NCT05509153·Phase 2

Apply to this trial

Huntington's Disease Biobank: Advancing Remote Monitoring and Deep Phenotyping

for Huntington Disease

1 site in Palo Alto

Sponsor: Stanford University

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT06941662

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Gait Analysis Parameter and Upper Limb Evaluation in Adult Patients With Neurological or Metabolic Pathology

for Neuromuscular Diseases

Sponsor: Centre Hospitalier Universitaire de Liege

Sex: All·Age: 18+

Code: NCT07136844

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Innovative Imaging and Cognitive BIOmarkers to Predict Huntington's Disease Progression

for Huntington Disease

Sponsor: Assistance Publique - Hôpitaux de Paris

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT05808153

Apply to this trial

Long Term Follow-up Grafted Huntington's Disease Patients

for Huntington Disease

Sponsor: Assistance Publique - Hôpitaux de Paris

Sex: All·Age: 18+

Code: NCT06194006

Extracellular Vesicles for HD

for Huntington Disease

1 site in Orlando

Sponsor: University of Central Florida

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT06082713

Apply to this trial

Home-based Transcranial Direct Current Stimulation Open Trial for Behavioral and Cognitive Symptoms in Huntington's Disease

for Huntington Disease

1 site in Houston

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: 18 - 80

Code: NCT05326451

Apply to this trial

Trial of the Combined Use of Thiamine and Biotin in Patients With Huntington's Disease

for Huntington Disease

Sponsor: Fundación Pública Andaluza para la gestión de la Investigación en Sevilla

Sex: All·Age: 18+

Code: NCT04478734·Phase 2

Apply to this trial

A Safety and Pharmacokinetics Trial of VO659 in SCA1, SCA3 and HD

for Spinocerebellar Ataxia Type 1

Sponsor: Vico Therapeutics B. V.

Sex: All·Age: 25 - 60

Code: NCT05822908·Phase 1, Phase 2

Apply to this trial

NYSCF Scientific Discovery Biobank

for ALS

1 site in New York

Sponsor: New York Stem Cell Foundation Research Institute

Sex: All·Age: 30 Days+

Code: NCT06203106

Apply to this trial

IMarkHD: in Vivo Longitudinal Imaging of HD Pathology

for Huntington Disease

Sponsor: King's College London

Sex: All·Age: 21 - 75·Accepts healthy volunteers

Code: NCT03434548

Apply to this trial

Study of BDNF Pathway Biomarkers in the Cerebrospinal Fluid in Patients With Huntington's Disease

for Huntington Disease

Sponsor: University Hospital, Montpellier

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04012411

Apply to this trial

Retinal Imaging in Neurodegenerative Disease

for Alzheimer's Disease

1 site in Durham

Sponsor: Duke University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT03233646

Apply to this trial

Huntington disease clinical trials — common questions

Are huntington disease clinical trials free to join?

Yes. Participating in a huntington disease clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a huntington disease clinical trial?

Each huntington disease study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a huntington disease trial near me?

Use the location controls above. We'll show recruiting huntington disease trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many huntington disease trials are recruiting right now?

We're currently tracking roughly 20 recruiting huntington disease trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Huntington disease trials by city

Orlando, FL Boston, MA Columbus, OH Irvine, CA La Jolla, CA Palo Alto, CA

Related specialties

Neurology Brain disorders