Efficacy and Safety Study of BHV-7000 Monotherapy in Major Depression

Part of paid clinical trials in Phoenix, Arizona.

Sponsor
Biohaven Therapeutics Ltd.
Study ID
NCT06419608
Phase
PHASE2
Status
Completed

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 75 Years
Healthy Volunteers
Not accepted

Interventions

  • BHV-7000 — DRUG
    BHV-7000 75 mg taken once daily for 6 weeks
  • Placebo — DRUG
    Matching placebo taken once daily for 6 weeks

Study Details

The purpose of this study is to determine the efficacy and safety of BHV-7000 in participants with Major Depressive Disorder (MDD)

Key Dates

Start date
May 28, 2024
Status verified
Jan 2026
Primary completion
Nov 7, 2025
Completion
Nov 7, 2025

Study Design

Enrollment
336 participants (actual)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: BHV-7000
  • Placebo Comparator: Placebo

Primary Outcome Measure

Change in Montgomery- Åsberg Depression Rating Scale (MADRS) total score from baseline to week 6 [ Time Frame: Baseline to Week 6 ]

Locations (62)

FacilityCityStateZIPSite coordinators
IMA Clinical ResearchPhoenixArizona85012-
Pillar Clinical Research, LLCLittle RockArkansas72204-
WIRGLittle RockArkansas72211-
WRNRogersArkansas72758-
Advanced Research Center, Inc.AnaheimCalifornia92805-
CIT LABellflowerCalifornia90706-
IPMGChinoCalifornia91710-
WR-PRI EncinoEncinoCalifornia91316-
Collaborative Neuroscience Research, LLC (CenExel - CNS)Garden GroveCalifornia92845-
CalNeuro Research GroupLos AngelesCalifornia90025-
Excell Research, Inc.OceansideCalifornia92056-
NRC Research InstituteOrangeCalifornia92868-
Anderson Clinical ResearchRedlandsCalifornia92374-
CIT IERiversideCalifornia92506-
Lumos Clinical Research CenterSan JoseCalifornia95124-
StanfordStanfordCalifornia94305-
Cenexel CNSTorranceCalifornia90504-
Pacific Clinical Research Management GroupUplandCalifornia91786-
Sunwise Clinical ResearchWalnut CreekCalifornia94596-
MCB Clinical Research CentersColorado SpringsColorado80910-
UConn HealthFarmingtonConnecticut06030-
Optum Behavioral Care of Connecticut, PC dba Comprehensive Psychiatric Care of ConnecticutNorwichConnecticut06360-
Clinical Neuroscience Solutions, IncJacksonvilleFlorida32256-
Floridian Neuroscience InstituteMiami LakesFlorida33016-
Clinical Neuroscience Solutions, Inc.OrlandoFlorida32801-
K2 Medical ResearchTampaFlorida33607-
Neuroscience Research InstituteWest Palm BeachFlorida33407-
CenExel iResearch, LLCDecaturGeorgia30030-
CenExel iResearch, LLCSavannahGeorgia31405-
Uptown Research InstituteChicagoIllinois60640-
Revive Research Institute, Inc.ElginIllinois60123-
Collective Medical ResearchOverland ParkKansas66210-
Delricht ResearchNew OrleansLouisiana70115-
Headlands PharmasiteBaltimoreMaryland21208-
CBH HealthGaithersburgMaryland20877-
Boston Clinical TrialsBostonMassachusetts02131-
Copley ClinicalBostonMassachusetts02116-
Adams ClinicalWatertownMassachusetts02472-
Precise Clinical ResearchFlowoodMississippi39232-
Arch Clinical TrialsSt LouisMissouri63141-
IMA Clinical ResearchLas VegasNevada89102-
Bio Behavioral HealthToms RiverNew Jersey08755-
SPRI Clinical Trials, LLCBrooklynNew York11235-
Neurobehavioral Research, IncCedarhurstNew York11516-
Bioscience Research LLCMount KiscoNew York10549-
Berman ClinicalNew YorkNew York10029-
Icahn School of Medicine at Mount SinaiNew YorkNew York10029-
The Medical Research Network, LLCNew YorkNew York10128-
RBAStaten IslandNew York10329-
Lehigh Center for Clinical ResearchAllentownPennsylvania18104-
Suburban Research AssociatesMediaPennsylvania19063-
Scranton Medical InstituteMoosicPennsylvania18509-
Coastal Carolina Research CenterNorth CharlestonSouth Carolina29405-
Donald J. Garcia, MD, PA dba Austin Clinical Trial PartnersAustinTexas78737-
FutureSearch Trials of DallasDallasTexas75234-
Relaro Medical Trials, LLCDallasTexas75243-
InSite Clinical Research, LLCDeSotoTexas75115-
Red Oak Psychiatry Associates, PAHoustonTexas77373-
Aim TrialsPlanoTexas75093-
Grayline Research CenterWichita FallsTexas76309-
Alpine Reseach OrganizationClintonUtah84015-
Northwest Clinical Research CenterBellevueWashington98007-

Find similar trials in Phoenix, AZ

By condition
Depression
By specialty
PsychiatryMental healthBehavioral health
By research site
IMA Clinical Research· Phoenix, AZPillar Clinical Research, LLC· Little Rock, ARWIRG· Little Rock, ARWRN· Rogers, ARAdvanced Research Center, Inc.· Anaheim, CACIT LA· Bellflower, CA

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