Repetitive Transcranial Alternating Current Stimulation (rtACS) for the Treatment of Optic Neuropathies

Sponsor
National Taiwan University Hospital
Study ID
NCT07145073
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • DC-Stimulator MC — DEVICE
    Experimental：Participants will receive 10 days of repeated transcranial alternating current stimulation treatment in hospital.
  • DC-Stimulator MC — DEVICE
    Sham Comparator：Participants will receive 10 days of repeated transcranial alternating current stimulation treatment (no active stimulation) in hospital.

Study Details

The goal of this study is to see whether repeated transcranial alternating current stimulation can activate impaired retinal ganglion cells and improve both structural and functional outcomes in patients with glaucoma.

Key Dates

First listed
Aug 28, 2025
Start date
Jan 26, 2026
Status verified
Aug 2025
Primary completion
Dec 31, 2027
Completion
Dec 31, 2028

Study Design

Enrollment
188 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Repetitive Transcranial Alternating Current Stimulation treatment
    Participants will receive 10 days of repeated transcranial alternating current stimulation in hospital.
  • Sham Comparator: Sham Repetitive Transcranial Alternating Current Stimulation
    Participants will receive 10 days of repeated transcranial alternating current stimulation treatment (no active stimulation) in hospital.

Primary Outcome Measure

Change in visual field mean deviation (MD) from baseline to post-treatment [ Time Frame: From treatment initiation to 26 days after treatment initiation ]

Central Contacts

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