Novel Skin Barrier Product Versus Petrolatum for Skin Barrier Dysfunction

Sponsor
Makati Medical Center
Study ID
NCT07183423
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Novel barrier repair topical product — OTHER
    Novel barrier product (containing ceramide, virgin coconut oil, cholesterol)
  • Petrolatum — OTHER
    Petrolatum application

Study Details

The goal of this clinical trial is to learn if a novel barrier topical product works to treat barrier dysfunction in adults. It will also learn about the safety of the novel barrier topical product. The main questions it aims to answer are: Does the novel barrier topical product improve skin hydration, skin sebum, redness, and pigmentation? Does it improve subjective dryness and itch? Researchers will compare the novel barrier topical product to petrolatum (a gold standard occlusive barrier repair agent) to see how they are comparable in treating skin barrier dysfunction. Participants will: Apply the novel barrier topical product or petrolatum twice a day for 28 days Visit the clinic once a week for checkups and tests Keep a diary of their application of the assigned product

Key Dates

First listed
Sep 19, 2025
Start date
Aug 31, 2025
Status verified
Sep 2025
Primary completion
Sep 30, 2025
Completion
Oct 31, 2025

Study Design

Enrollment
26 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Right Arm: Applying Test Product
  • No Intervention: Left Arm: Applying no topicals
  • Active Comparator: Petrolatum: Right Arm: Applying Petrolatum

Primary Outcome Measure

Transepidermal water loss [ Time Frame: 28 days ]

Central Contacts

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